Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2)

Biochemistry

Volumn 44, Issue 24, 2005, Pages 8908-8917

  Banerjee, Antara ^a   Ray, Abhijit ^a   Chang, Cheng ^b   Swaan, Peter W ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; ORGANIC ACIDS; PROTEINS; SALTS; SUBSTRATES;

BILE SALTS; CYSTEIN; EXTRACELLULAR RESIDUES; METHANETHIOSULFONYL (MTS); SITE-DIRECETD MUTAGENESIS;

MUTAGENESIS;

ALANINE; BILE ACID; BILE SALT; CARRIER PROTEIN; CHENODEOXYCHOLIC ACID; CYSTEINE DERIVATIVE; MESYLIC ACID DERIVATIVE; PROTEIN SCL10A2; REAGENT; SCAFFOLD PROTEIN; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL ENGINEERING; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONJUGATION; GENE MUTATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; BILE ACIDS AND SALTS; DNA PRIMERS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS; THIOSULFONIC ACIDS;

EID: 20544471895     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050553s     Document Type: Article

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