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Volumn 47, Issue 12, 2008, Pages 3606-3614

Cytosolic half of transmembrane domain IV of the human bile acid transporter hASBT (SLC10A2) forms part of the substrate translocation pathway

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE EXPRESSION LEVELS; HUMAN BILE ACID TRANSPORTER (HASBT); SUBSTRATE TRANSLOCATION;

EID: 41149180595     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702498w     Document Type: Article
Times cited : (20)

References (34)
  • 3
  • 6
    • 0028866988 scopus 로고
    • Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity
    • Wong, M. H., Oelkers, P., and Dawson, P. A. (1995) Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity. J. Biol. Chem. 270, 27228-27234.
    • (1995) J. Biol. Chem , vol.270 , pp. 27228-27234
    • Wong, M.H.1    Oelkers, P.2    Dawson, P.A.3
  • 7
    • 0028039878 scopus 로고
    • Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter
    • Wong, M. H., Oelkers, P., Craddock, A. L., and Dawson, P. A. (1994) Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter. J. Biol. Chem. 269, 1340-1347.
    • (1994) J. Biol. Chem , vol.269 , pp. 1340-1347
    • Wong, M.H.1    Oelkers, P.2    Craddock, A.L.3    Dawson, P.A.4
  • 8
    • 0034718614 scopus 로고    scopus 로고
    • Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties
    • Lazaridis, K. N., Tietz, P., Wu, T., Kip, S., Dawson, P. A., and LaRusso, N. F. (2000) Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties. Proc. Natl. Acad. Sci. U.S.A. 97, 11092-11097.
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 11092-11097
    • Lazaridis, K.N.1    Tietz, P.2    Wu, T.3    Kip, S.4    Dawson, P.A.5    LaRusso, N.F.6
  • 9
    • 0032567523 scopus 로고    scopus 로고
    • Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic
    • Weinman, S. A., Carruth, M. W., and Dawson, P. A. (1998) Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic. J. Biol. Chem. 273, 34691-34695.
    • (1998) J. Biol. Chem , vol.273 , pp. 34691-34695
    • Weinman, S.A.1    Carruth, M.W.2    Dawson, P.A.3
  • 10
    • 31044434123 scopus 로고    scopus 로고
    • Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains
    • Banerjee, A., and Swaan, P. W. (2006) Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains. Biochemistry 45, 943-953.
    • (2006) Biochemistry , vol.45 , pp. 943-953
    • Banerjee, A.1    Swaan, P.W.2
  • 11
    • 4444299420 scopus 로고    scopus 로고
    • Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2)
    • Zhang, E. Y., Phelps, M. A., Banerjee, A., Khantwal, C. M., Chang, C., Helsper, F., and Swaan, P. W. (2004) Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2). Biochemistry 43, 11380-11392.
    • (2004) Biochemistry , vol.43 , pp. 11380-11392
    • Zhang, E.Y.1    Phelps, M.A.2    Banerjee, A.3    Khantwal, C.M.4    Chang, C.5    Helsper, F.6    Swaan, P.W.7
  • 13
    • 0037827787 scopus 로고    scopus 로고
    • Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter
    • Chen, F., Ma, L., Dawson, P. A., Sinal, C. J., Sehayek, E., Gonzalez, F. J., Breslow, J., Ananthanarayanan, M., and Shneider, B. L. (2003) Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. J. Biol. Chem. 278, 19909-19916.
    • (2003) J. Biol. Chem , vol.278 , pp. 19909-19916
    • Chen, F.1    Ma, L.2    Dawson, P.A.3    Sinal, C.J.4    Sehayek, E.5    Gonzalez, F.J.6    Breslow, J.7    Ananthanarayanan, M.8    Shneider, B.L.9
  • 14
    • 3042828426 scopus 로고    scopus 로고
    • Bile acid-induced negative feedback regulation of the human ileal bile acid transporter
    • Neimark, E., Chen, F., Li, X., and Shneider, B. L. (2004) Bile acid-induced negative feedback regulation of the human ileal bile acid transporter. Hepatology 40, 149-156.
    • (2004) Hepatology , vol.40 , pp. 149-156
    • Neimark, E.1    Chen, F.2    Li, X.3    Shneider, B.L.4
  • 15
    • 0029068229 scopus 로고
    • Inhibition of ileal sodium-dependent bile acid transport by 2164U90
    • Root, C., Smith, C. D., Winegar, D. A., Brieaddy, L. E., and Lewis, M. C. (1995) Inhibition of ileal sodium-dependent bile acid transport by 2164U90. J. Lipid Res. 36, 1106-1115.
    • (1995) J. Lipid Res , vol.36 , pp. 1106-1115
    • Root, C.1    Smith, C.D.2    Winegar, D.A.3    Brieaddy, L.E.4    Lewis, M.C.5
  • 16
    • 0034646603 scopus 로고    scopus 로고
    • Farnesoid X receptor responds to bile acids and represses cholesterol 7α-hydroxylase gene (CYP7A1) transcription
    • Chiang, J. Y., Kimmel, R., Weinberger, C., and Stroup, D. (2000) Farnesoid X receptor responds to bile acids and represses cholesterol 7α-hydroxylase gene (CYP7A1) transcription. J. Biol. Chem. 275, 10918-10924.
    • (2000) J. Biol. Chem , vol.275 , pp. 10918-10924
    • Chiang, J.Y.1    Kimmel, R.2    Weinberger, C.3    Stroup, D.4
  • 18
    • 0344309204 scopus 로고    scopus 로고
    • SC-435, an ileal apical sodium codependent bile acid transporter (ASBT) inhibitor lowers plasma cholesterol and reduces atherosclerosis in guinea pigs
    • West, K. L., Zern, T. L., Butteiger, D. N., Keller, B. T., and Fernandez, M. L. (2003) SC-435, an ileal apical sodium codependent bile acid transporter (ASBT) inhibitor lowers plasma cholesterol and reduces atherosclerosis in guinea pigs. Atherosclerosis 171, 201-210.
    • (2003) Atherosclerosis , vol.171 , pp. 201-210
    • West, K.L.1    Zern, T.L.2    Butteiger, D.N.3    Keller, B.T.4    Fernandez, M.L.5
  • 19
    • 24944565175 scopus 로고    scopus 로고
    • Tremont, S. J., Lee, L. F., Huang, H. C., Keller, B. T., Banerjee, S. C., Both, S. R., Carpenter, A. J., Wang, C. C., Garland, D. J., Huang, W., Jones, C., Koeller, K. J., Kolodziej, S. A., Li, J., Manning, R. E., Mahoney, M. W., Miller, R. E., Mischke, D. A., Rath, N. P., Fletcher, T., Reinhard, E. J., Tollefson, M. B., Vernier, W. F., Wagner, G. M., Rapp, S. R., Beaudry, J., Glenn, K., Regina, K., Schuh, J. R., Smith, M. E., Trivedi, J. S., and Reitz, D. B. (2005) Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (part 1). J. Med. Chem. 48, 5837-5852.
    • Tremont, S. J., Lee, L. F., Huang, H. C., Keller, B. T., Banerjee, S. C., Both, S. R., Carpenter, A. J., Wang, C. C., Garland, D. J., Huang, W., Jones, C., Koeller, K. J., Kolodziej, S. A., Li, J., Manning, R. E., Mahoney, M. W., Miller, R. E., Mischke, D. A., Rath, N. P., Fletcher, T., Reinhard, E. J., Tollefson, M. B., Vernier, W. F., Wagner, G. M., Rapp, S. R., Beaudry, J., Glenn, K., Regina, K., Schuh, J. R., Smith, M. E., Trivedi, J. S., and Reitz, D. B. (2005) Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (part 1). J. Med. Chem. 48, 5837-5852.
  • 20
    • 24744470290 scopus 로고    scopus 로고
    • Huang, H. C., Tremont, S. J., Lee, L. F., Keller, B. T., Carpenter, A. J., Wang, C. C., Banerjee, S. C., Both, S. R., Fletcher, T., Garland, D. J., Huang, W., Jones, C., Koeller, K. J., Kolodziej, S. A., Li, J., Manning, R. E., Mahoney, M. W., Miller, R. E., Mischke, D. A., Rath, N. P., Reinhard, E. J., Tollefson, M. B., Vernier, W. F., Wagner, G. M., Rapp, S. R., Beaudry, J., Glenn, K., Regina, K., Schuh, J. R., Smith, M. E., Trivedi, J. S., and Reitz, D. B. (2005) Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (part 2). J. Med. Chem. 48, 5853-5868.
    • Huang, H. C., Tremont, S. J., Lee, L. F., Keller, B. T., Carpenter, A. J., Wang, C. C., Banerjee, S. C., Both, S. R., Fletcher, T., Garland, D. J., Huang, W., Jones, C., Koeller, K. J., Kolodziej, S. A., Li, J., Manning, R. E., Mahoney, M. W., Miller, R. E., Mischke, D. A., Rath, N. P., Reinhard, E. J., Tollefson, M. B., Vernier, W. F., Wagner, G. M., Rapp, S. R., Beaudry, J., Glenn, K., Regina, K., Schuh, J. R., Smith, M. E., Trivedi, J. S., and Reitz, D. B. (2005) Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (part 2). J. Med. Chem. 48, 5853-5868.
  • 21
    • 0031193858 scopus 로고    scopus 로고
    • Enhanced transepithelial transport of peptides by conjugation to cholic acid
    • Swaan, P. W., Hillgren, K. M., Szoka, F. C., Jr., and Oie, S. (1997) Enhanced transepithelial transport of peptides by conjugation to cholic acid. Bioconjugate Chem. 8, 520-525.
    • (1997) Bioconjugate Chem , vol.8 , pp. 520-525
    • Swaan, P.W.1    Hillgren, K.M.2    Szoka Jr., F.C.3    Oie, S.4
  • 22
    • 4544232586 scopus 로고    scopus 로고
    • Increased acyclovir oral bioavailability via a bile acid conjugate
    • Tolle-Sander, S., Lentz, K. A., Maeda, D. Y., Coop, A., and Polli, J. E. (2004) Increased acyclovir oral bioavailability via a bile acid conjugate. Mol. Pharm. 1, 40-48.
    • (2004) Mol. Pharm , vol.1 , pp. 40-48
    • Tolle-Sander, S.1    Lentz, K.A.2    Maeda, D.Y.3    Coop, A.4    Polli, J.E.5
  • 23
    • 33751290454 scopus 로고    scopus 로고
    • Transmembrane domain VII of the human apical sodium-dependent bile acid transporter ASBT (SLC10A2) lines the substrate translocation pathway
    • Hussainzada, N., Banerjee, A., and Swaan, P. W. (2006) Transmembrane domain VII of the human apical sodium-dependent bile acid transporter ASBT (SLC10A2) lines the substrate translocation pathway. Mol. Pharmacol. 70, 1565-1574.
    • (2006) Mol. Pharmacol , vol.70 , pp. 1565-1574
    • Hussainzada, N.1    Banerjee, A.2    Swaan, P.W.3
  • 24
    • 0037062563 scopus 로고    scopus 로고
    • Organization of the membrane domain of the human liver sodium/bile acid cotransporter
    • Hallen, S., Mareninova, O., Branden, M., and Sachs, G. (2002) Organization of the membrane domain of the human liver sodium/bile acid cotransporter. Biochemistry 41, 7253-7266.
    • (2002) Biochemistry , vol.41 , pp. 7253-7266
    • Hallen, S.1    Mareninova, O.2    Branden, M.3    Sachs, G.4
  • 25
    • 0030944084 scopus 로고    scopus 로고
    • Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)
    • Oelkers, P., Kirby, L. C., Heubi, J. E., and Dawson, P. A. (1997) Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). J. Clin. Invest. 99, 1880-1887.
    • (1997) J. Clin. Invest , vol.99 , pp. 1880-1887
    • Oelkers, P.1    Kirby, L.C.2    Heubi, J.E.3    Dawson, P.A.4
  • 26
    • 20544471895 scopus 로고    scopus 로고
    • Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2)
    • Banerjee, A., Ray, A., Chang, C., and Swaan, P. W. (2005) Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2). Biochemistry 44, 8908-8917.
    • (2005) Biochemistry , vol.44 , pp. 8908-8917
    • Banerjee, A.1    Ray, A.2    Chang, C.3    Swaan, P.W.4
  • 27
    • 0034612365 scopus 로고    scopus 로고
    • Inhibition of the human sodium/bile acid cotransporters by side-specific methanethiosulfonate sulfhydryl reagents: Substrate-controlled accessibility of site of inactivation
    • Hallen, S., Fryklund, J., and Sachs, G. (2000) Inhibition of the human sodium/bile acid cotransporters by side-specific methanethiosulfonate sulfhydryl reagents: Substrate-controlled accessibility of site of inactivation. Biochemistry 39, 6743-6750.
    • (2000) Biochemistry , vol.39 , pp. 6743-6750
    • Hallen, S.1    Fryklund, J.2    Sachs, G.3
  • 29
    • 33745194374 scopus 로고    scopus 로고
    • Identification of functionally relevant residues of the rat ileal apical sodium-dependent bile acid cotransporter
    • Sun, A. Q., Balasubramaniyan, N., Chen, H., Shahid, M., and Suchy, F. J. (2006) Identification of functionally relevant residues of the rat ileal apical sodium-dependent bile acid cotransporter. J. Biol. Chem. 281, 16410-16418.
    • (2006) J. Biol. Chem , vol.281 , pp. 16410-16418
    • Sun, A.Q.1    Balasubramaniyan, N.2    Chen, H.3    Shahid, M.4    Suchy, F.J.5
  • 30
    • 38549107239 scopus 로고    scopus 로고
    • Conformational flexibility of helix VI is essential for substrate permeation of the human apical sodium-dependent bile acid transporter (ASBT)
    • Hussainzada, N., Khandewal, A., and Swaan, P. W. (2008) Conformational flexibility of helix VI is essential for substrate permeation of the human apical sodium-dependent bile acid transporter (ASBT). Mol. Pharmacol. 73, 305-313.
    • (2008) Mol. Pharmacol , vol.73 , pp. 305-313
    • Hussainzada, N.1    Khandewal, A.2    Swaan, P.W.3
  • 31
    • 33751290454 scopus 로고    scopus 로고
    • Transmembrane domain VII of the human apical sodium-dependent bile acid transporter ASBT (SLC10A2) lines the substrate translocation pathway
    • Hussainzada, N., Banerjee, A., and Swaan, P. W. (2006) Transmembrane domain VII of the human apical sodium-dependent bile acid transporter ASBT (SLC10A2) lines the substrate translocation pathway. Mol. Pharmacol. 70, 1565-1574.
    • (2006) Mol. Pharmacol , vol.70 , pp. 1565-1574
    • Hussainzada, N.1    Banerjee, A.2    Swaan, P.W.3
  • 32
    • 0036314934 scopus 로고    scopus 로고
    • Structural mimicry of proline kinks: Tertiary packing interactions support local structural distortions
    • Ceruso, M. A., and Weinstein, H. (2002) Structural mimicry of proline kinks: Tertiary packing interactions support local structural distortions. J. Mol. Biol. 318, 1237-1249.
    • (2002) J. Mol. Biol , vol.318 , pp. 1237-1249
    • Ceruso, M.A.1    Weinstein, H.2
  • 33
    • 33748486707 scopus 로고    scopus 로고
    • Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA
    • Hassan, K. A., Galea, M., Wu, J., Mitchell, B. A., Skurray, R. A., and Brown, M. H. (2006) Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA. FEMS Microbiol. Lett. 263, 76-85.
    • (2006) FEMS Microbiol. Lett , vol.263 , pp. 76-85
    • Hassan, K.A.1    Galea, M.2    Wu, J.3    Mitchell, B.A.4    Skurray, R.A.5    Brown, M.H.6
  • 34
    • 0036430199 scopus 로고    scopus 로고
    • Proline-induced distortions of transmembrane helices
    • Cordes, F. S., Bright, J. N., and Sansom, M. S. (2002) Proline-induced distortions of transmembrane helices. J. Mol. Biol. 323, 951-960.
    • (2002) J. Mol. Biol , vol.323 , pp. 951-960
    • Cordes, F.S.1    Bright, J.N.2    Sansom, M.S.3


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