Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7α-hydroxylase

Metabolism: Clinical and Experimental

Volumn 53, Issue 7, 2004, Pages 927-932

  Li, Hai ^a   Xu, Guorong ^b   Shang, Quan ^c   Pan, Luxing ^c   Shefer, Sarah ^c   Batta, Ashok K ^c   Bollineni, Jaya ^c   Tint, G Stephen ^c   Keller, Brad T ^c   Salen, Gerald ^c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

APICAL SODIUM DEPENDENT BILE ACID COTRANSPORTER; BILE ACID; BILE SALT; BINDING PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; COTRANSPORTER; CYTOCHROME P450; FARNESOID X RECEPTOR; MESSENGER RNA; PROTEIN INHIBITOR; SC 435; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BILE ACID METABOLISM; BILE ACID SYNTHESIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENTEROHEPATIC CIRCULATION; GENE EXPRESSION; GENE TARGETING; MALABSORPTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RABBIT;

ANIMALS; BILE; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT, ACTIVE; BLOTTING, NORTHERN; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CYCLIC N-OXIDES; CYCLOPHILINS; DNA-BINDING PROTEINS; FECES; ILEUM; LIVER; MALE; RABBITS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TROPANES;

EID: 3042662820     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2004.01.017     Document Type: Article

References (31)

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