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Volumn 3, Issue 6, 2003, Pages 995-1000

Therapeutic value of alpha-4 integrin blockade in inflammatory bowel disease: The role of natalizumab

Author keywords

4 integrin; Crohn's disease; MADCAM 1; Natalizumab

Indexed keywords

ALICAFORSEN; ALPHA4 INTEGRIN; ANTIBIOTIC AGENT; AZATHIOPRINE; C REACTIVE PROTEIN; CORTICOSTEROID; INFLIXIMAB; INTERCELLULAR ADHESION MOLECULE 1; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; MLN 02; MONOCLONAL ANTIBODY; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; NATALIZUMAB; PLACEBO; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 0041334132     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/eobt.3.6.995.21264     Document Type: Review
Times cited : (23)

References (11)
  • 1
    • 0032576359 scopus 로고    scopus 로고
    • Acquired increase in leukocyte binding by intestinal microvascular endothelium in inflammatory bowel disease
    • BINION DG, WEST GA, VOLK EE et al.: Acquired increase in leukocyte binding by intestinal microvascular endothelium in inflammatory bowel disease. Lancet (1998) 352:1742-1746.
    • (1998) Lancet , vol.352 , pp. 1742-1746
    • Binion, D.G.1    West, G.A.2    Volk, E.E.3
  • 2
    • 0036110371 scopus 로고    scopus 로고
    • A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin
    • GORDON FH, HAMILTON MI, DONOGHUE S et al.: A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin. Aliment Pharmacol. Ther. (2002) 16:699-705.
    • (2002) Aliment Pharmacol. Ther. , vol.16 , pp. 699-705
    • Gordon, F.H.1    Hamilton, M.I.2    Donoghue, S.3
  • 3
    • 0034903450 scopus 로고    scopus 로고
    • A randomised placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease
    • GORDON FH, LAI CWY, HAMILTON MI et al.: A randomised placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease. Gastroenterology (2001) 121:268-274.
    • (2001) Gastroenterology , vol.121 , pp. 268-274
    • Gordon, F.H.1    Lai, C.W.Y.2    Hamilton, M.I.3
  • 4
    • 0027248939 scopus 로고
    • Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody
    • PODOLSKY DK, LOBB R, KING N et al.: Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody. J. Clin. Invest. (1993) 92:372-380.
    • (1993) J. Clin. Invest. , vol.92 , pp. 372-380
    • Podolsky, D.K.1    Lobb, R.2    King, N.3
  • 6
    • 0037413468 scopus 로고    scopus 로고
    • Natalizumab for active Crohn's disease
    • GHOSH S, GOLDIN E, GORDON F et al.: Natalizumab for active Crohn's disease. N. Engl. J. Med. (2003) 348:24-32.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 24-32
    • Ghosh, S.1    Goldin, E.2    Gordon, F.3
  • 7
    • 0031782392 scopus 로고    scopus 로고
    • A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease
    • YACYCHYN BR, BOWEN-YACYSHYN MB, JEWELL L et al.: A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. Gastroenterology (1998) 114:1133-1142.
    • (1998) Gastroenterology , vol.114 , pp. 1133-1142
    • Yacychyn, B.R.1    Bowen-Yacyshyn, M.B.2    Jewell, L.3
  • 8
    • 0035045185 scopus 로고    scopus 로고
    • Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease
    • SCHREIBER S, NIKOLAUS S, MALCHOW H et al.: Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease. Gastroenterology (2001) 120:1339-1346.
    • (2001) Gastroenterology , vol.120 , pp. 1339-1346
    • Schreiber, S.1    Nikolaus, S.2    Malchow, H.3
  • 10
    • 0042651174 scopus 로고    scopus 로고
    • homepage
    • http://www.elan.com Elan Corp. homepage
  • 11
    • 0042150289 scopus 로고    scopus 로고
    • homepage
    • http://www.biogen.com Biogen homepage


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.