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Volumn 159, Issue 1, 1997, Pages 279-289

Refocusing Neutralizing Antibody Response by Targeted Dampening of an Immunodominant Epitope

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; VIRUS ANTIBODY;

EID: 0031180974     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (139)

References (76)
  • 1
    • 0025833615 scopus 로고
    • Strategies of obligate intracellular parasites for evading host defenses
    • Hall, B. F., and K. A. Joiner. 1991. Strategies of obligate intracellular parasites for evading host defenses. Immunol. Today 12:A22.
    • (1991) Immunol. Today , vol.12
    • Hall, B.F.1    Joiner, K.A.2
  • 2
    • 0028117165 scopus 로고
    • Subversion of the immune system by pathogens
    • Marrack, P., and J. Kappler. 1994. Subversion of the immune system by pathogens. Cell 76:323.
    • (1994) Cell , vol.76 , pp. 323
    • Marrack, P.1    Kappler, J.2
  • 3
    • 0030070476 scopus 로고    scopus 로고
    • Compositional similarities between the human immunodeficiency virus and surface antigens of pathogens
    • Fitzgerald, D. J., E. D. Bronson, and J. N. Anderson. 1996. Compositional similarities between the human immunodeficiency virus and surface antigens of pathogens. AIDS Res. Hum. Retroviruses 12:99.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 99
    • Fitzgerald, D.J.1    Bronson, E.D.2    Anderson, J.N.3
  • 4
    • 0022550776 scopus 로고
    • Genetic variation in AIDS viruses
    • Coffin, J. M. 1986. Genetic variation in AIDS viruses. Cell 46:1.
    • (1986) Cell , vol.46 , pp. 1
    • Coffin, J.M.1
  • 6
    • 0025851330 scopus 로고
    • Neutralization of HIV-1: A paradox of humoral proportions
    • Nara, P. L., R. R. Garrity, and J. Goudsmit, 1991. Neutralization of HIV-1: a paradox of humoral proportions. FASEB J. 5:2437.
    • (1991) FASEB J. , vol.5 , pp. 2437
    • Nara, P.L.1    Garrity, R.R.2    Goudsmit, J.3
  • 7
    • 0342798713 scopus 로고
    • Site-directed mutations introduced into the V3 domain of HIV-1 gp120 result in an augmented humoral response to other epitopes
    • E. Norrby, F. Brown, R. M. Chanock, and H. S. Ginsberg, eds. CSH Press, Cold Spring Harbor, NY
    • Garrity, R. R., G. Rimmelzwaan, A. Minassian, W-P. Tsai, G. Lin, S. Conley, N. Dunlop, J. de Jong, W. Keulen, J. Moore, J. Goudsmit, and P. Nara. 1994. Site-directed mutations introduced into the V3 domain of HIV-1 gp120 result in an augmented humoral response to other epitopes. In Vaccines 94. E. Norrby, F. Brown, R. M. Chanock, and H. S. Ginsberg, eds. CSH Press, Cold Spring Harbor, NY. pp. 261-267.
    • (1994) Vaccines 94 , pp. 261-267
    • Garrity, R.R.1    Rimmelzwaan, G.2    Minassian, A.3    Tsai, W.-P.4    Lin, G.5    Conley, S.6    Dunlop, N.7    De Jong, J.8    Keulen, W.9    Moore, J.10    Goudsmit, J.11    Nara, P.12
  • 9
    • 0043080631 scopus 로고
    • Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees
    • Goudsmit, J., C. Debouck, R. H. Meloen, L. Smit, M. Bakker, D. M. Asher, A. V. Wolff, C. J. Gibbs, Jr., and D. C. Gajdusek. 1988. Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees. Proc. Natl. Acad. Sci. USA 85: 4478.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4478
    • Goudsmit, J.1    Debouck, C.2    Meloen, R.H.3    Smit, L.4    Bakker, M.5    Asher, D.M.6    Wolff, A.V.7    Gibbs Jr., C.J.8    Gajdusek, D.C.9
  • 10
    • 0025362335 scopus 로고
    • Emergence of viruses resistant to neutralizution by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees
    • Nara, P. L., L. Smit, N. Dunlop, W. Hatch, M. Merges, D. Waters, J. Kelliher, R. C. Gallo, P. J. Fischinger, and J. Goudsmit. 1990. Emergence of viruses resistant to neutralizution by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees. J. Virol. 64:3779.
    • (1990) J. Virol. , vol.64 , pp. 3779
    • Nara, P.L.1    Smit, L.2    Dunlop, N.3    Hatch, W.4    Merges, M.5    Waters, D.6    Kelliher, J.7    Gallo, R.C.8    Fischinger, P.J.9    Goudsmit, J.10
  • 13
    • 8944248384 scopus 로고
    • Clinical trials of candidate AIDS vaccines
    • Walker M. C., and P. E. Fast. 1994. Clinical trials of candidate AIDS vaccines. AIDS 8(Suppl. 1):S213.
    • (1994) AIDS , vol.8 , Issue.SUPPL. 1
    • Walker, M.C.1    Fast, P.E.2
  • 17
    • 0023107134 scopus 로고
    • Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: Prediction of antigenic epitopes in conserved and variable regions
    • Modrow, S., B. H. Hahn, G. M. Shaw, R. C. Gallo, F. Wong-Staal, and H. Wolf. 1987. Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions. J. Virol. 61:570.
    • (1987) J. Virol. , vol.61 , pp. 570
    • Modrow, S.1    Hahn, B.H.2    Shaw, G.M.3    Gallo, R.C.4    Wong-Staal, F.5    Wolf, H.6
  • 18
    • 0030031567 scopus 로고    scopus 로고
    • Kernel density analysis of variable and conserved regions of the envelope proteins of human immunodeficiency virus type 1 and associated epilopes
    • Lauder, I. J., J. L. Hsiang, J. Lin, E. B. Siwak, and F. B. Hollinger. 1996. Kernel density analysis of variable and conserved regions of the envelope proteins of human immunodeficiency virus type 1 and associated epilopes. AIDS Res. Hum. Retroviruses 12:91.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 91
    • Lauder, I.J.1    Hsiang, J.L.2    Lin, J.3    Siwak, E.B.4    Hollinger, F.B.5
  • 19
    • 0026595148 scopus 로고
    • Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120
    • Fung, M. S., C. R. Sun, W. L. Gordon, R. S. Liou, T. W. Chang, W. N. Sun, E. S. Daar, and D. D. Ho. 1992. Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120. J. Virol. 66:848.
    • (1992) J. Virol. , vol.66 , pp. 848
    • Fung, M.S.1    Sun, C.R.2    Gordon, W.L.3    Liou, R.S.4    Chang, T.W.5    Sun, W.N.6    Daar, E.S.7    Ho, D.D.8
  • 20
    • 0027204667 scopus 로고
    • Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody
    • Sullivan, N., M. Thali, C. Furman, D. D. Ho, and J. Sodroski. 1993. Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody. J. Virol. 67:3674.
    • (1993) J. Virol. , vol.67 , pp. 3674
    • Sullivan, N.1    Thali, M.2    Furman, C.3    Ho, D.D.4    Sodroski, J.5
  • 21
    • 0027170414 scopus 로고
    • Strain specificity and binding affinity requirements of neutralizing monoclonal antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1
    • Nakamura, G. R., R. Byrn, D. M. Wilkes, J. A. Fox, M. R. Hobbs, R. Hastings, H. C. Wessling, M. A. Norcross, B. M. Fendly, and P. W. Berman. 1993. Strain specificity and binding affinity requirements of neutralizing monoclonal antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1. J. Virol. 67:6179.
    • (1993) J. Virol. , vol.67 , pp. 6179
    • Nakamura, G.R.1    Byrn, R.2    Wilkes, D.M.3    Fox, J.A.4    Hobbs, M.R.5    Hastings, R.6    Wessling, H.C.7    Norcross, M.A.8    Fendly, B.M.9    Berman, P.W.10
  • 24
    • 0027159948 scopus 로고
    • Construction of an HIV-1 peptide vaccine containing a multi-determinant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations
    • Ahlers, J. D., C. D. Pendleton, N. Dunlop, A. Minassian, P. L. Nara. and J. A. Berzofsky. 1993. Construction of an HIV-1 peptide vaccine containing a multi-determinant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations. J. Immunol. 150:5647.
    • (1993) J. Immunol. , vol.150 , pp. 5647
    • Ahlers, J.D.1    Pendleton, C.D.2    Dunlop, N.3    Minassian, A.4    Nara, P.L.5    Berzofsky, J.A.6
  • 25
    • 0028092161 scopus 로고
    • Antibodies to the HIV-1 V3 loop in serum from infected persons contribute a major proportion of immune effector functions including complement activation, antibody binding, and neutralization
    • Spear, G. T., D. M. Takefman, S. Sharpe, M. Ghassemi, and S. Zolla-Pazner. 1994. Antibodies to the HIV-1 V3 loop in serum from infected persons contribute a major proportion of immune effector functions including complement activation, antibody binding, and neutralization. Virology 204:609.
    • (1994) Virology , vol.204 , pp. 609
    • Spear, G.T.1    Takefman, D.M.2    Sharpe, S.3    Ghassemi, M.4    Zolla-Pazner, S.5
  • 26
    • 0028174548 scopus 로고
    • Frequent and early HIV-1 MN neutralizing capacity in sera from Dutch HIV-1 seroconverters is related to antibody reactivity to peptides from the gp120 V3 domain
    • Zwart, G., N. K. Back, C. Ramautarsing, M. Valk, L. van der Hoek, and J. Goudsmit. 1994. Frequent and early HIV-1 MN neutralizing capacity in sera from Dutch HIV-1 seroconverters is related to antibody reactivity to peptides from the gp120 V3 domain. AIDS Res. Hum. Retroviruses 10:245.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 245
    • Zwart, G.1    Back, N.K.2    Ramautarsing, C.3    Valk, M.4    Van der Hoek, L.5    Goudsmit, J.6
  • 27
    • 0026444130 scopus 로고
    • Clonal dominance: Cause for a limited and failing immune response to HIV-1 infection and vaccination
    • Kohler, H., J. Goudsmit, and P. Nara. 1992. Clonal dominance: cause for a limited and failing immune response to HIV-1 infection and vaccination. J. Acquired Immune Defic. Syndr. 5:158.
    • (1992) J. Acquired Immune Defic. Syndr. , vol.5 , pp. 158
    • Kohler, H.1    Goudsmit, J.2    Nara, P.3
  • 28
    • 0027488833 scopus 로고
    • B-cell abnormalities in AIDS: Stable and clonally restricted antibody response in HIV-1 infection
    • Muller, S., H. Wang, G. J. Silverman, G. Bramlet, N. Haigwood, and H. Kohler. 1993. B-cell abnormalities in AIDS: stable and clonally restricted antibody response in HIV-1 infection. Scand. J. Immunol. 38:327.
    • (1993) Scand. J. Immunol. , vol.38 , pp. 327
    • Muller, S.1    Wang, H.2    Silverman, G.J.3    Bramlet, G.4    Haigwood, N.5    Kohler, H.6
  • 29
    • 0028969888 scopus 로고
    • Does the HIV-1 manipulate immune network via gp120 immunoglobulin-like domain involving V3 loop?
    • Metlas, R., and V. Veljkovic. 1995. Does the HIV-1 manipulate immune network via gp120 immunoglobulin-like domain involving V3 loop? Vaccine 13:355.
    • (1995) Vaccine , vol.13 , pp. 355
    • Metlas, R.1    Veljkovic, V.2
  • 30
    • 0025958022 scopus 로고
    • Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody
    • Ho, D. D., J. A. McKeating, X. L. Li, T. Moudgil, H. S. Daar, NC. Sun, and J. E. Robinson. 1991. Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody. J. Virol. 65:489.
    • (1991) J. Virol. , vol.65 , pp. 489
    • Ho, D.D.1    McKeating, J.A.2    Li, X.L.3    Moudgil, T.4    Daar, H.S.5    Sun, N.C.6    Robinson, J.E.7
  • 31
    • 0025775863 scopus 로고
    • Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/CD4 binding in human immunodeficiency virus 1-infected humans
    • Kang, C. Y., P. Nara, S. Chamat, V. Caralli, T. Ryskamp, N. Haigwood, R. Newman, and H. Kohler. 1991. Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/CD4 binding in human immunodeficiency virus 1-infected humans. Proc. Natl. Acad. Sci. USA 88:6171.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6171
    • Kang, C.Y.1    Nara, P.2    Chamat, S.3    Caralli, V.4    Ryskamp, T.5    Haigwood, N.6    Newman, R.7    Kohler, H.8
  • 32
    • 0024794173 scopus 로고
    • Human immunodeficiency virus 1: Predominance of a group-specific neutralizing epitope that persists despite genetic variation
    • Berkower, I., G. E. Smith, C. Giri, and D. Murphy, 1989. Human immunodeficiency virus 1: predominance of a group-specific neutralizing epitope that persists despite genetic variation. J. Exp. Med. 170:681.
    • (1989) J. Exp. Med. , vol.170 , pp. 681
    • Berkower, I.1    Smith, G.E.2    Giri, C.3    Murphy, D.4
  • 33
    • 0025292473 scopus 로고
    • Epitopes recognized by the neutralizing antibodies of un HIV-1-infected individual
    • Profy, A. T., P. A. Salinas, L. I. Eckler, N. M. Dunlop, P. L. Nuru, and S. D. Putney. 1990. Epitopes recognized by the neutralizing antibodies of un HIV-1-infected individual. J. Immunol. 144:4641.
    • (1990) J. Immunol. , vol.144 , pp. 4641
    • Profy, A.T.1    Salinas, P.A.2    Eckler, L.I.3    Dunlop, N.M.4    Nuru, P.L.5    Putney, S.D.6
  • 34
    • 0027397052 scopus 로고
    • Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans
    • Moore, J. P., and D. D. Ho. 1993. Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans. J. Virol. 67:863.
    • (1993) J. Virol. , vol.67 , pp. 863
    • Moore, J.P.1    Ho, D.D.2
  • 35
    • 0025066116 scopus 로고
    • Identification of conserved and variant epitopes of human immunodeficiency virus type 1 (HIV-1) gp120 by human monoclonal antibodies produced by EBV-transformed cell lines
    • Robinson, J. E., D. Holton, S. Pacheco-Morell, J. Liu, and H. McMurdo. 1990. Identification of conserved and variant epitopes of human immunodeficiency virus type 1 (HIV-1) gp120 by human monoclonal antibodies produced by EBV-transformed cell lines. AIDS Res. Hum. Retroviruses 6:567.
    • (1990) AIDS Res. Hum. Retroviruses , vol.6 , pp. 567
    • Robinson, J.E.1    Holton, D.2    Pacheco-Morell, S.3    Liu, J.4    McMurdo, H.5
  • 36
    • 0026001658 scopus 로고
    • An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection
    • Posner, M. R., T. Hideshima, T. Cannon, M. Mukherjee, K. H. Mayer, and R. A. Byrn. 1991. An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection. J. Immunol. 146:4325.
    • (1991) J. Immunol. , vol.146 , pp. 4325
    • Posner, M.R.1    Hideshima, T.2    Cannon, T.3    Mukherjee, M.4    Mayer, K.H.5    Byrn, R.A.6
  • 37
    • 0028001662 scopus 로고
    • Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120
    • Bagley, J., P. J. Dillon, C. Rosen, J. Robinson, J. Sodroski, and W. A. Marasco. 1994. Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120. Mol. Immunol. 31:1149.
    • (1994) Mol. Immunol. , vol.31 , pp. 1149
    • Bagley, J.1    Dillon, P.J.2    Rosen, C.3    Robinson, J.4    Sodroski, J.5    Marasco, W.A.6
  • 38
    • 0023275999 scopus 로고
    • Persistent infection of chimpanzees with human immunodeficiency virus: Serological responses and properties of reisolated viruses
    • Nara, P. L., W. G. Robey, L. O. Arthur, D. M. Asher, A. V. Wolff, C. J. Gibbs, Jr., D. C. Gajdusek, and P. J. Fischinger. 1987. Persistent infection of chimpanzees with human immunodeficiency virus: serological responses and properties of reisolated viruses. J. Virol. 61:3173.
    • (1987) J. Virol. , vol.61 , pp. 3173
    • Nara, P.L.1    Robey, W.G.2    Arthur, L.O.3    Asher, D.M.4    Wolff, A.V.5    Gibbs Jr., C.J.6    Gajdusek, D.C.7    Fischinger, P.J.8
  • 39
    • 0023889606 scopus 로고
    • Temporal development of cross-neutralization between HTLV-III B and HTLV-HI RF in experimentally infected chimpanzees
    • Goudsmit, J., C. Thiriart, L. Smit, C. Bruck, and C. J. Gibbs. 1988. Temporal development of cross-neutralization between HTLV-III B and HTLV-HI RF in experimentally infected chimpanzees. Vaccine 6:229.
    • (1988) Vaccine , vol.6 , pp. 229
    • Goudsmit, J.1    Thiriart, C.2    Smit, L.3    Bruck, C.4    Gibbs, C.J.5
  • 40
    • 0024512861 scopus 로고
    • Prospects for prevention of and early intervention against HIV
    • Bolognesi, D. P. 1989. Prospects for prevention of and early intervention against HIV. J. Am. Med. Assoc. 261:3007.
    • (1989) J. Am. Med. Assoc. , vol.261 , pp. 3007
    • Bolognesi, D.P.1
  • 42
    • 0026501677 scopus 로고
    • Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity
    • de Jong, J. J., J. Goudsmit, W. Keulen, B. Klaver, W. Krone, M. Tersmette, and A. de Ronde. 1992. Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity. J. Virol. 66:757.
    • (1992) J. Virol. , vol.66 , pp. 757
    • De Jong, J.J.1    Goudsmit, J.2    Keulen, W.3    Klaver, B.4    Krone, W.5    Tersmette, M.6    De Ronde, A.7
  • 43
    • 0000498346 scopus 로고
    • Expression of proteins in mammalian cells using vaccinia
    • F. M. Ausubet, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, eds. Greene Publishing Associates and Wiley-Interscience, New York
    • Earl, P., and B. Moss. 1990. Expression of proteins in mammalian cells using vaccinia. In Current Protocols in Molecular Biology, Vol 2, F. M. Ausubet, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, eds. Greene Publishing Associates and Wiley-Interscience, New York, pp. 16.15.1-16.18.9.
    • (1990) Current Protocols in Molecular Biology , vol.2 , pp. 16151-16189
    • Earl, P.1    Moss, B.2
  • 44
    • 0024412748 scopus 로고
    • Human immunodeficiency virus glycoproteins: Lectin binding properties
    • Hammar, L., S. Eriksson, and B. Morein. 1989. Human immunodeficiency virus glycoproteins: lectin binding properties. AIDS Res. Hum. Retroviruses 5:495.
    • (1989) AIDS Res. Hum. Retroviruses , vol.5 , pp. 495
    • Hammar, L.1    Eriksson, S.2    Morein, B.3
  • 47
    • 0023853928 scopus 로고
    • Quantitative infectivity assay for HIV-1 and-2
    • Nara, P. L., and P. J. Fischinger. 1988. Quantitative infectivity assay for HIV-1 and-2. Nature 332:469.
    • (1988) Nature , vol.332 , pp. 469
    • Nara, P.L.1    Fischinger, P.J.2
  • 48
    • 0021891884 scopus 로고
    • Assembly of asparagine-linked oligosaccharides
    • Kornfeld, R., and S. Kornfeld. 1985. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 54:631.
    • (1985) Annu. Rev. Biochem. , vol.54 , pp. 631
    • Kornfeld, R.1    Kornfeld, S.2
  • 50
    • 0023684064 scopus 로고
    • A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions
    • Higuchi, R., B. Krummel, and R. K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res, 16:7351.
    • (1988) Nucleic Acids Res , vol.16 , pp. 7351
    • Higuchi, R.1    Krummel, B.2    Saiki, R.K.3
  • 52
    • 0345016834 scopus 로고
    • Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: Role of carbohydrate in binding and cell fusion
    • Matthews, T. J., K. J. Weinhold, H. K. Lyerly, A. J. Langlois, H. Wigzell, and D. P. Bolognesi. 1987. Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion. Proc. Natl. Acad. Sci. USA 84:5424.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 5424
    • Matthews, T.J.1    Weinhold, K.J.2    Lyerly, H.K.3    Langlois, A.J.4    Wigzell, H.5    Bolognesi, D.P.6
  • 53
    • 0025292252 scopus 로고
    • Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type I recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
    • Leonard, C. K., M. W. Spellman, L. Riddle, R. J. Harris, J. N. Thomas, and T. J. Gregory. 1990. Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type I recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J. Biol. Chem. 265:10,373.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10373
    • Leonard, C.K.1    Spellman, M.W.2    Riddle, L.3    Harris, R.J.4    Thomas, J.N.5    Gregory, T.J.6
  • 55
    • 85045798086 scopus 로고
    • Structural requirements of N-glycosylation of proteins: Studies with proline peptides as conformational probes
    • Bause, E. 1983. Structural requirements of N-glycosylation of proteins: studies with proline peptides as conformational probes. Biochem. J. 209:33.
    • (1983) Biochem. J. , vol.209 , pp. 33
    • Bause, E.1
  • 56
    • 0026002948 scopus 로고
    • Solution conformational preferences of immunogenic peptides derived from the principal neutralizing determinant of the HIV-1 envelope glycoprotein gp120
    • Chandrasekhar, K., A. T. Profy, and H. J. Dyson. 1991. Solution conformational preferences of immunogenic peptides derived from the principal neutralizing determinant of the HIV-1 envelope glycoprotein gp120. Biochemistry 30:9187.
    • (1991) Biochemistry , vol.30 , pp. 9187
    • Chandrasekhar, K.1    Profy, A.T.2    Dyson, H.J.3
  • 57
    • 0025525792 scopus 로고
    • Peptide component vaccine engineering: Targeting the AIDS virus
    • Cease, K. B. 1990. Peptide component vaccine engineering: targeting the AIDS virus. Int. Rev. Immunol. 7:85.
    • (1990) Int. Rev. Immunol. , vol.7 , pp. 85
    • Cease, K.B.1
  • 59
    • 0027234624 scopus 로고
    • Evidence that the structural conformation of envelope gp120 affects human immunodeficiency virus type 1 infectivity, host range, and syncytium-forming ability
    • Stamatatos, L., and C. Cheng-Mayer. 1993. Evidence that the structural conformation of envelope gp120 affects human immunodeficiency virus type 1 infectivity, host range, and syncytium-forming ability. J. Virol. 67:5635.
    • (1993) J. Virol. , vol.67 , pp. 5635
    • Stamatatos, L.1    Cheng-Mayer, C.2
  • 61
    • 0028296816 scopus 로고
    • HIV-1 gp41 shares a common immunologic determinant with human T, B and monocyte cell lines
    • Chen, Y. H., A. Susanna, G. Bock, F. Steindl, H. Katinger, and M. P. Dierich. 1994. HIV-1 gp41 shares a common immunologic determinant with human T, B and monocyte cell lines. Immunol. Lett. 39:219.
    • (1994) Immunol. Lett. , vol.39 , pp. 219
    • Chen, Y.H.1    Susanna, A.2    Bock, G.3    Steindl, F.4    Katinger, H.5    Dierich, M.P.6
  • 62
    • 0028244285 scopus 로고
    • An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization
    • Back, N. K., L. Smit, J. J. De Jong, W. Keulen, M. Schutten, J. Goudsmit, and M. Tersmette. 1994. An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. Virology 199:431.
    • (1994) Virology , vol.199 , pp. 431
    • Back, N.K.1    Smit, L.2    De Jong, J.J.3    Keulen, W.4    Schutten, M.5    Goudsmit, J.6    Tersmette, M.7
  • 63
    • 0027194743 scopus 로고
    • Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions
    • Wyatt, R., N. Sullivan, M. Thali, H. Repke, D. Ho, J. Robinson, M. Posner, and J. Sodroski. 1993. Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions. J. Virol. 67:4557.
    • (1993) J. Virol. , vol.67 , pp. 4557
    • Wyatt, R.1    Sullivan, N.2    Thali, M.3    Repke, H.4    Ho, D.5    Robinson, J.6    Posner, M.7    Sodroski, J.8
  • 64
    • 0025253819 scopus 로고
    • Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
    • Olshevsky, U., E. Helseth, C. Furman, J. Li, W. Haseltine, and J. Sodroski. 1990. Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding. J. Virol. 64:5701.
    • (1990) J. Virol. , vol.64 , pp. 5701
    • Olshevsky, U.1    Helseth, E.2    Furman, C.3    Li, J.4    Haseltine, W.5    Sodroski, J.6
  • 65
    • 0026801056 scopus 로고
    • Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glyco-protein
    • Thali, M., C. Furman, D. D. Ho, J. Robinson, S. Tilley, A. Pinter, and J. Sodroski. 1992. Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glyco-protein. J. Virol. 66:5635.
    • (1992) J. Virol. , vol.66 , pp. 5635
    • Thali, M.1    Furman, C.2    Ho, D.D.3    Robinson, J.4    Tilley, S.5    Pinter, A.6    Sodroski, J.7
  • 67
    • 0028321596 scopus 로고
    • Temporal analysis of the antibody response to HIV envelope protein in HIV-infected laboratory workers
    • Pincus, S. H., K. G. Messer, P. L. Nara, W. A. Blattner, G. Colclough, and M. Reitz. 1994. Temporal analysis of the antibody response to HIV envelope protein in HIV-infected laboratory workers. J. Clin. Invest. 93:2505.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2505
    • Pincus, S.H.1    Messer, K.G.2    Nara, P.L.3    Blattner, W.A.4    Colclough, G.5    Reitz, M.6
  • 68
    • 0027311936 scopus 로고
    • Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120
    • Gorny, M. K., J. Y. Xu, S. Karwowska, A. Buchbinder, and S. Zolla-Pazner. 1993. Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120. J. Immunol. 150:635.
    • (1993) J. Immunol. , vol.150 , pp. 635
    • Gorny, M.K.1    Xu, J.Y.2    Karwowska, S.3    Buchbinder, A.4    Zolla-Pazner, S.5
  • 69
    • 0025139114 scopus 로고
    • B cell epitope mapping of human immunodeficiency virus envelope glycoproteins with long (19- to 36-residue) synthetic peptides
    • Neurath, A. R., N. Strick, and E. S. Lee. 1990. B cell epitope mapping of human immunodeficiency virus envelope glycoproteins with long (19- to 36-residue) synthetic peptides. J. Gen. Virol. 71:85.
    • (1990) J. Gen. Virol. , vol.71 , pp. 85
    • Neurath, A.R.1    Strick, N.2    Lee, E.S.3
  • 71
    • 0028107775 scopus 로고
    • Antigen-specific early primary humoral responses modulate immunodominance of B cell epitopes
    • Vijayakrishnan, L., V. Kumar, J. N. Agrewala, G. C. Mishra, and K. V. Rao. 1994. Antigen-specific early primary humoral responses modulate immunodominance of B cell epitopes. J. Immunol. 153:1613.
    • (1994) J. Immunol. , vol.153 , pp. 1613
    • Vijayakrishnan, L.1    Kumar, V.2    Agrewala, J.N.3    Mishra, G.C.4    Rao, K.V.5
  • 73
    • 1542584708 scopus 로고
    • Mapping neutralizing epitopes near the fusion segment of HIV gp41
    • F. Brown, R. M. Chanock, H. S. Ginsberg, and R. A. Lerner, eds. CSH Press, Cold Spring Harbor, NY
    • Cease, K. B., W. S. Probert, L. M. Groenveld, N. M. Dunlop, and P. L. Nara. 1992. Mapping neutralizing epitopes near the fusion segment of HIV gp41. In Vaccines 92. F. Brown, R. M. Chanock, H. S. Ginsberg, and R. A. Lerner, eds. CSH Press, Cold Spring Harbor, NY. pp. 201-204.
    • (1992) Vaccines 92 , pp. 201-204
    • Cease, K.B.1    Probert, W.S.2    Groenveld, L.M.3    Dunlop, N.M.4    Nara, P.L.5
  • 74
    • 0020516865 scopus 로고
    • Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome
    • Lane, H. C., H. Masur, L. C. Edgar, G. Whalen, A. H. Rook, and A. S. Fauci. 1983. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 309:453.
    • (1983) N. Engl. J. Med. , vol.309 , pp. 453
    • Lane, H.C.1    Masur, H.2    Edgar, L.C.3    Whalen, G.4    Rook, A.H.5    Fauci, A.S.6
  • 75
    • 0023240958 scopus 로고
    • Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity
    • Martinez-Maza, O., E. Crabb, R. T. Mitsuyasu, J. L. Fahey, and J. V. Giorgi. 1987. Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity. J. Immunol. 138:138.
    • (1987) J. Immunol. , vol.138 , pp. 138
    • Martinez-Maza, O.1    Crabb, E.2    Mitsuyasu, R.T.3    Fahey, J.L.4    Giorgi, J.V.5
  • 76
    • 43949157657 scopus 로고
    • Deceptive imprinting in the immune response against HIV-1
    • Kohler, H., Müller, S. and P. L. Nara. 1994. Deceptive imprinting in the immune response against HIV-1. Immunol. Today 15:475.
    • (1994) Immunol. Today , vol.15 , pp. 475
    • Kohler, H.1    Müller, S.2    Nara, P.L.3


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