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Volumn 84, Issue 4, 2009, Pages 617-629

Metabolism of fluoroorganic compounds in microorganisms: Impacts for the environment and the production of fine chemicals

Author keywords

Biodegradation; Biotransformation; Drug metabolism; F 19 NMR; Mutasynthesis; Natural products

Indexed keywords

BIOTRANSFORMATION; DRUG METABOLISM; F-19 NMR; MUTASYNTHESIS; NATURAL PRODUCTS;

EID: 69949169225     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2127-0     Document Type: Short Survey
Times cited : (54)

References (125)
  • 1
    • 0028558554 scopus 로고
    • Directed biosynthesis of 5″-fluoropactamycin in Streptomyces pactum
    • ES Adams KL Rinehart 1994 Directed biosynthesis of 5″- fluoropactamycin in Streptomyces pactum J Antibiot 47 1456 1465
    • (1994) J Antibiot , vol.47 , pp. 1456-1465
    • Adams, E.S.1    Rinehart, K.L.2
  • 2
    • 0032807198 scopus 로고    scopus 로고
    • Biodegradability of cefotiam, ciprofloxacin, meropenem, penicillin G, and sulfamethoxazole and inhibition of waste water bacteria
    • A Al-Ahmad FD Daschner K Kummerer 1999 Biodegradability of cefotiam, ciprofloxacin, meropenem, penicillin G, and sulfamethoxazole and inhibition of waste water bacteria Arch Environ Con Tox 37 158 163
    • (1999) Arch Environ Con Tox , vol.37 , pp. 158-163
    • Al-Ahmad, A.1    Daschner, F.D.2    Kummerer, K.3
  • 3
    • 46249123248 scopus 로고    scopus 로고
    • Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues
    • B Amir-Heidari J Thirlway J Micklefield 2008 Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues Org Biomol Chem 6 975 978
    • (2008) Org Biomol Chem , vol.6 , pp. 975-978
    • Amir-Heidari, B.1    Thirlway, J.2    Micklefield, J.3
  • 5
    • 33748934565 scopus 로고    scopus 로고
    • Preparation of erythromycin analogs having functional groups at C-15
    • GW Ashley, et al. 2006 Preparation of erythromycin analogs having functional groups at C-15 J Antibiot 59 392 401
    • (2006) J Antibiot , vol.59 , pp. 392-401
    • Ashley, G.W.1
  • 7
    • 33845351827 scopus 로고    scopus 로고
    • Fluorine: An invaluable tool in medicinal chemistry
    • Begue JP, Bonnet-Delpon D (2006a) Fluorine: an invaluable tool in medicinal chemistry. Actual Chimique:83-87
    • (2006) Actual Chimique , pp. 83-87
    • Begue, J.P.1    Bonnet-Delpon, D.2
  • 8
    • 33746356860 scopus 로고    scopus 로고
    • Recent advances (1995-2005) in fluorinated pharmaceuticals based on natural products
    • JP Begue D Bonnet-Delpon 2006 Recent advances (1995-2005) in fluorinated pharmaceuticals based on natural products J Fluorine Chem 127 992 1012
    • (2006) J Fluorine Chem , vol.127 , pp. 992-1012
    • Begue, J.P.1    Bonnet-Delpon, D.2
  • 9
    • 0346080764 scopus 로고
    • Biosynthesis of penicillins. 4. New crystalline biosynthetic penicillins
    • OK Behrens, et al. 1948 Biosynthesis of penicillins. 4. New crystalline biosynthetic penicillins J Biol Chem 175 793 809
    • (1948) J Biol Chem , vol.175 , pp. 793-809
    • Behrens, O.K.1
  • 11
    • 0023757118 scopus 로고
    • Pharmacokinetics and human-tissue penetration of flurithromycin
    • G Benoni, et al. 1988 Pharmacokinetics and human-tissue penetration of flurithromycin Antimicrob Agents Chemother 32 1875 1878
    • (1988) Antimicrob Agents Chemother , vol.32 , pp. 1875-1878
    • Benoni, G.1
  • 15
    • 0027527424 scopus 로고
    • The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. 4. Preparation of fluorinated squalestatins by directed biosynthesis
    • RJP Cannell, et al. 1993 The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. 4. Preparation of fluorinated squalestatins by directed biosynthesis J Antibiot 46 1381 1389
    • (1993) J Antibiot , vol.46 , pp. 1381-1389
    • Cannell, R.J.P.1
  • 17
    • 0029994409 scopus 로고    scopus 로고
    • Initial oxidative and subsequent conjugative metabolites produced during the metabolism of phenanthrene by fungi
    • RP Casillas SA Crow TM Heinze J Deck CE Cerniglia 1996 Initial oxidative and subsequent conjugative metabolites produced during the metabolism of phenanthrene by fungi J Ind Microbiol 16 205 215
    • (1996) J Ind Microbiol , vol.16 , pp. 205-215
    • Casillas, R.P.1    Crow, S.A.2    Heinze, T.M.3    Deck, J.4    Cerniglia, C.E.5
  • 19
    • 0028077274 scopus 로고
    • The preparation of zaragozic acid analogs by directed biosynthesis
    • TS Chen, et al. 1994 The preparation of zaragozic acid analogs by directed biosynthesis J Antibiot 47 1290 1294
    • (1994) J Antibiot , vol.47 , pp. 1290-1294
    • Chen, T.S.1
  • 20
    • 84957943700 scopus 로고
    • H.T. Clarke J.R. Johnson R. Robinson (eds). Princeton University Press Princeton
    • Clarke HT, Johnson JR, Robinson R (eds) (1949) The chemistry of penicillin. Princeton University Press, Princeton
    • (1949)
  • 21
    • 0035543764 scopus 로고    scopus 로고
    • The potential of F-19 NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism
    • O Corcoran JC Lindon R Hall IM Ismail JK Nicholson 2001 The potential of F-19 NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism Analyst 126 2103 2106
    • (2001) Analyst , vol.126 , pp. 2103-2106
    • Corcoran, O.1    Lindon, J.C.2    Hall, R.3    Ismail, I.M.4    Nicholson, J.K.5
  • 22
    • 0032473856 scopus 로고    scopus 로고
    • Evidence for an octanoate synthase operating during the biosynthesis of piliformic acid in Poronia piliformis
    • H Culceth J Fuchser SJ Moss J Nieschalk D O'Hagan 1998 Evidence for an octanoate synthase operating during the biosynthesis of piliformic acid in Poronia piliformis Tetrahedron Lett 39 1949 1952
    • (1998) Tetrahedron Lett , vol.39 , pp. 1949-1952
    • Culceth, H.1    Fuchser, J.2    Moss, S.J.3    Nieschalk, J.4    O'Hagan, D.5
  • 23
    • 0038070590 scopus 로고    scopus 로고
    • γ-Fluorinated analogues of glutamic acid and glutamine
    • R Dave B Badet P Meffre 2003 γ-Fluorinated analogues of glutamic acid and glutamine Amino Acids 24 245 261
    • (2003) Amino Acids , vol.24 , pp. 245-261
    • Dave, R.1    Badet, B.2    Meffre, P.3
  • 24
    • 53849101806 scopus 로고    scopus 로고
    • The fluorinase, the chlorinase and the Duf-62 enzymes
    • H Deng D O'Hagan 2008 The fluorinase, the chlorinase and the Duf-62 enzymes Curr Opin Chem Biol 12 582 592
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 582-592
    • Deng, H.1    O'Hagan, D.2
  • 25
    • 11144334620 scopus 로고    scopus 로고
    • Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya
    • H Deng D O'Hagan C Schaffrath 2004 Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya Nat Prod Rep 21 773 784
    • (2004) Nat Prod Rep , vol.21 , pp. 773-784
    • Deng, H.1    O'Hagan, D.2    Schaffrath, C.3
  • 26
    • 33645460289 scopus 로고    scopus 로고
    • Fluorinase mediated C-F-18 bond formation, an enzymatic tool for PET labeling
    • Deng H et al (2006) Fluorinase mediated C-F-18 bond formation, an enzymatic tool for PET labelling. Chem Commun 652-654
    • (2006) Chem Commun , pp. 652-654
    • Deng, H.1
  • 27
    • 10044258574 scopus 로고    scopus 로고
    • Improved bioconversion of 15-fluoro-6-deoxyerythronolide B to 15-fluoro-erythromycin A by overexpression of the eryK gene in Saccharopolyspora erythraea
    • RP Desai E Rodriguez JL Galazzo P Licari 2004 Improved bioconversion of 15-fluoro-6-deoxyerythronolide B to 15-fluoro-erythromycin A by overexpression of the eryK gene in Saccharopolyspora erythraea Biotechnol Prog 20 1660 1665
    • (2004) Biotechnol Prog , vol.20 , pp. 1660-1665
    • Desai, R.P.1    Rodriguez, E.2    Galazzo, J.L.3    Licari, P.4
  • 28
    • 1142310932 scopus 로고    scopus 로고
    • Crystal structure and mechanism of a bacterial fluorinating enzyme
    • CJ Dong, et al. 2004 Crystal structure and mechanism of a bacterial fluorinating enzyme Nature 427 561 565
    • (2004) Nature , vol.427 , pp. 561-565
    • Dong, C.J.1
  • 29
    • 36248957567 scopus 로고    scopus 로고
    • Bacterial defluorination of 4-fluoroglutamic acid
    • C Donnelly CD Murphy 2007 Bacterial defluorination of 4-fluoroglutamic acid Appl Microbiol Biotechnol 77 699 703
    • (2007) Appl Microbiol Biotechnol , vol.77 , pp. 699-703
    • Donnelly, C.1    Murphy, C.D.2
  • 30
    • 58149197803 scopus 로고    scopus 로고
    • Purification and properties of fluoroacetate dehalogenase from Pseudomonas fluorescens DSM 8341
    • C Donnelly CD Murphy 2009 Purification and properties of fluoroacetate dehalogenase from Pseudomonas fluorescens DSM 8341 Biotechnol Lett 31 245 250
    • (2009) Biotechnol Lett , vol.31 , pp. 245-250
    • Donnelly, C.1    Murphy, C.D.2
  • 31
    • 0023758106 scopus 로고
    • Bacterial metabolism of side-chain fluorinated aromatics - Co-metabolism of 3-trifluoromethyl(TFM)-benzoate by Pseudomonas putida (Arvilla) MT-2 and Rhodococcus rubropertinctus N657
    • KH Engesser RB Cain HJ Knackmuss 1988 Bacterial metabolism of side-chain fluorinated aromatics - co-metabolism of 3-trifluoromethyl(TFM)-benzoate by Pseudomonas putida (Arvilla) MT-2 and Rhodococcus rubropertinctus N657 Arch Microbiol 149 188 197
    • (1988) Arch Microbiol , vol.149 , pp. 188-197
    • Engesser, K.H.1    Cain, R.B.2    Knackmuss, H.J.3
  • 32
    • 0025264137 scopus 로고
    • Bacterial metabolism of side-chain fluorinated aromatics - Unproductive meta-cleavage of 3-trifluoromethylcatechol
    • KH Engesser MA Rubio HJ Knackmuss 1990 Bacterial metabolism of side-chain fluorinated aromatics - unproductive meta-cleavage of 3-trifluoromethylcatechol Appl Microbiol Biotechnol 32 600 608
    • (1990) Appl Microbiol Biotechnol , vol.32 , pp. 600-608
    • Engesser, K.H.1    Rubio, M.A.2    Knackmuss, H.J.3
  • 33
    • 45749125659 scopus 로고    scopus 로고
    • Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome
    • AS Eustaquio BS Moore 2008 Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome Angew Chem Int Edit 47 3936 3938
    • (2008) Angew Chem Int Edit , vol.47 , pp. 3936-3938
    • Eustaquio, A.S.1    Moore, B.S.2
  • 34
    • 37249024344 scopus 로고    scopus 로고
    • Discovery and characterization of a marine bacterial SAM-dependent chlorinase
    • AS Eustaquio F Pojer JP Noe BS Moore 2008 Discovery and characterization of a marine bacterial SAM-dependent chlorinase Nat Chem Biol 4 69 74
    • (2008) Nat Chem Biol , vol.4 , pp. 69-74
    • Eustaquio, A.S.1    Pojer, F.2    Noe, J.P.3    Moore, B.S.4
  • 35
    • 0037455147 scopus 로고    scopus 로고
    • Salinosporamide A: A highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus Salinospora
    • RH Feling GO Buchanan TJ Mincer CA Kauffman PR Jensen W Fenical 2003 Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus Salinospora Angew Chem Int Edit 42 355 357
    • (2003) Angew Chem Int Edit , vol.42 , pp. 355-357
    • Feling, R.H.1    Buchanan, G.O.2    Mincer, T.J.3    Kauffman, C.A.4    Jensen, P.R.5    Fenical, W.6
  • 37
    • 0027485481 scopus 로고
    • The atmospheric degradation and impact of 1, 1, 1, 2-tetrafluoroethane (hydrofluorocarbon 134a)
    • J Franklin 1993 The atmospheric degradation and impact of 1, 1, 1, 2-tetrafluoroethane (hydrofluorocarbon 134a) Chemosphere 27 1565 1601
    • (1993) Chemosphere , vol.27 , pp. 1565-1601
    • Franklin, J.1
  • 38
    • 0014408998 scopus 로고
    • Preparation of substituted phenyl pyrroles through metabolism of tryptophan analogues
    • M Gorman RL Hamill RP Elander J Mabe 1968 Preparation of substituted phenyl pyrroles through metabolism of tryptophan analogues Biochem Biophys Res Commun 31 294 299
    • (1968) Biochem Biophys Res Commun , vol.31 , pp. 294-299
    • Gorman, M.1    Hamill, R.L.2    Elander, R.P.3    Mabe, J.4
  • 39
    • 23944437163 scopus 로고    scopus 로고
    • A novel fluorinated erythromycin antibiotic
    • Goss RJM, Hong H (2005) A novel fluorinated erythromycin antibiotic. Chem Commun 3983-3985
    • (2005) Chem Commun , pp. 3983-3985
    • Goss, R.J.M.1    Hong, H.2
  • 40
    • 0032866767 scopus 로고    scopus 로고
    • Degradation of 4-fluorobiphenyl by mycorrhizal fungi as determined by F-19 nuclear magnetic resonance spectroscopy and C-14 radiolabelling analysis
    • NA Green AA Meharg C Till J Troke JK Nicholson 1999 Degradation of 4-fluorobiphenyl by mycorrhizal fungi as determined by F-19 nuclear magnetic resonance spectroscopy and C-14 radiolabelling analysis Appl Environ Microbiol 65 4021 4027
    • (1999) Appl Environ Microbiol , vol.65 , pp. 4021-4027
    • Green, N.A.1    Meharg, A.A.2    Till, C.3    Troke, J.4    Nicholson, J.K.5
  • 41
    • 0031664574 scopus 로고    scopus 로고
    • Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning
    • K Gregg B Hamdorf K Henderson J Kopecny C Wong 1998 Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning Appl Environ Microbiol 64 3496 3498
    • (1998) Appl Environ Microbiol , vol.64 , pp. 3496-3498
    • Gregg, K.1    Hamdorf, B.2    Henderson, K.3    Kopecny, J.4    Wong, C.5
  • 42
    • 0034042860 scopus 로고    scopus 로고
    • Studies of precursor-directed biosynthesis with streptomyces, 3-structural diversity of 1-O-acyl alpha-L-rhamnopyranosides by precursor-directed biosynthesis with Streptomyces griseoviridis
    • S Grond I Papastavrou A Zeeck 2000 Studies of precursor-directed biosynthesis with streptomyces, 3-structural diversity of 1-O-acyl alpha-L-rhamnopyranosides by precursor-directed biosynthesis with Streptomyces griseoviridis Eur J Org Chem 2000 1875 1881
    • (2000) Eur J Org Chem , vol.2000 , pp. 1875-1881
    • Grond, S.1    Papastavrou, I.2    Zeeck, A.3
  • 43
    • 0014785428 scopus 로고
    • Metabolism of tryptophan by Pseudomonas aureofaciens. 3. Production of substituted pyrrolnitrins from tryptophan analogues
    • RL Hamill RP Elander JA Mabe M Gorman 1970 Metabolism of tryptophan by Pseudomonas aureofaciens. 3. Production of substituted pyrrolnitrins from tryptophan analogues Appl Microbiol 19 721 725
    • (1970) Appl Microbiol , vol.19 , pp. 721-725
    • Hamill, R.L.1    Elander, R.P.2    Mabe, J.A.3    Gorman, M.4
  • 44
    • 65549084218 scopus 로고    scopus 로고
    • Comparison of planktonic and biofilm cultures of Pseudomonas fluorescens DSM8341 cells grown on fluoroacetate
    • B Heffernan CD Murphy E Casey AA Patchett 2009 Comparison of planktonic and biofilm cultures of Pseudomonas fluorescens DSM8341 cells grown on fluoroacetate Appl Environ Microbiol 75 2899 2907
    • (2009) Appl Environ Microbiol , vol.75 , pp. 2899-2907
    • Heffernan, B.1    Murphy, C.D.2    Casey, E.3    Patchett, A.A.4
  • 46
    • 0037703072 scopus 로고    scopus 로고
    • Novel soraphens from precursor directed biosynthesis
    • Hill AM, Thompson BL (2003) Novel soraphens from precursor directed biosynthesis. Chem Commun 1360-1361
    • (2003) Chem Commun , pp. 1360-1361
    • Hill, A.M.1    Thompson, B.L.2
  • 47
    • 0023721770 scopus 로고
    • On the biosynthesis of asperlicin and the directed biosynthesis of analogs in Aspergillus alliaceus
    • DR Houck J Ondeyka DL Zink E Inamine MA Goetz OD Hensens 1988 On the biosynthesis of asperlicin and the directed biosynthesis of analogs in Aspergillus alliaceus J Antibiot 41 882 891
    • (1988) J Antibiot , vol.41 , pp. 882-891
    • Houck, D.R.1    Ondeyka, J.2    Zink, D.L.3    Inamine, E.4    Goetz, M.A.5    Hensens, O.D.6
  • 48
    • 10044251967 scopus 로고    scopus 로고
    • Directed biosynthesis of fluorinated pseurotin A, synerazol and gliotoxin
    • Y Igarashi, et al. 2004 Directed biosynthesis of fluorinated pseurotin A, synerazol and gliotoxin J Antibiot 57 748 754
    • (2004) J Antibiot , vol.57 , pp. 748-754
    • Igarashi, Y.1
  • 49
    • 33645454126 scopus 로고    scopus 로고
    • Fluorine in medicinal chemistry: A review of anti-cancer agents
    • C Isanbor D O'Hagan 2006 Fluorine in medicinal chemistry: a review of anti-cancer agents J Fluorine Chem 127 303 319
    • (2006) J Fluorine Chem , vol.127 , pp. 303-319
    • Isanbor, C.1    O'Hagan, D.2
  • 52
    • 0017161152 scopus 로고
    • 4′-Substituted nucleosides. 2. Synthesis of nucleoside antibiotic nucleocidin
    • ID Jenkins JPH Verheyden JG Moffatt 1976 4′-Substituted nucleosides. 2. Synthesis of nucleoside antibiotic nucleocidin J Am Chem Soc 98 3346 3357
    • (1976) J Am Chem Soc , vol.98 , pp. 3346-3357
    • Jenkins, I.D.1    Verheyden, J.P.H.2    Moffatt, J.G.3
  • 53
    • 65249098870 scopus 로고    scopus 로고
    • X-ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp Strain FA1
    • K Jitsumori, et al. 2009 X-ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp Strain FA1 J Bacteriol 191 2630 2637
    • (2009) J Bacteriol , vol.191 , pp. 2630-2637
    • Jitsumori, K.1
  • 54
    • 0142011978 scopus 로고    scopus 로고
    • Incorporation of fluorinated fatty acids into emulsan by Acinetobacter calcoaceticus RAG-1
    • AK Johri M Yalpani DL Kaplan 2003 Incorporation of fluorinated fatty acids into emulsan by Acinetobacter calcoaceticus RAG-1 Biochem Eng J 16 175 181
    • (2003) Biochem Eng J , vol.16 , pp. 175-181
    • Johri, A.K.1    Yalpani, M.2    Kaplan, D.L.3
  • 56
    • 33744492329 scopus 로고    scopus 로고
    • Outlines of an "exploding" network of metabolites generated from the fluoroquinolone enrofloxacin by the brown rot fungus Gloeophyllum striatum
    • W Karl J Schneider HG Wetzstein 2006 Outlines of an "exploding" network of metabolites generated from the fluoroquinolone enrofloxacin by the brown rot fungus Gloeophyllum striatum Appl Microbiol Biotechnol 71 101 113
    • (2006) Appl Microbiol Biotechnol , vol.71 , pp. 101-113
    • Karl, W.1    Schneider, J.2    Wetzstein, H.G.3
  • 57
    • 0004813217 scopus 로고
    • Purification, crystallization and properties of haloacetate halidohydrolase from Pseudomonas species
    • H Kawasaki K Miyoshi K Tonomura 1981 Purification, crystallization and properties of haloacetate halidohydrolase from Pseudomonas species Agric Biol Chem 45 543 544
    • (1981) Agric Biol Chem , vol.45 , pp. 543-544
    • Kawasaki, H.1    Miyoshi, K.2    Tonomura, K.3
  • 58
    • 0022414293 scopus 로고
    • 19F NMR spectroscopy. I. Fluorinated vulgamycins
    • A Kawashima H Seto M Kato K Uchida N Otake 1985 Preparation of fluorinated antibiotics followed by F-19 NMR-spectroscopy. 1. Fluorinated vulgamycins J Antibiot 38 1499 1505 (Pubitemid 16217838)
    • (1985) Journal of Antibiotics , vol.38 , Issue.11 , pp. 1499-1505
    • Kawashima, A.1    Seto, H.2    Kato, M.3
  • 59
    • 0022354195 scopus 로고
    • 19F NMR spectroscopy. II. Fluorinated actinomycins
    • A Kawashima H Seto M Kato A Yasuda K Uchida N Otake 1985 Preparation of fluorinated antibiotics followed by F-19 NMR-spectroscopy. 2. Fluorinated actinomycins J Antibiot 38 1625 1628 (Pubitemid 16217856)
    • (1985) Journal of Antibiotics , vol.38 , Issue.11 , pp. 1625-1628
    • Kawashima, A.1    Seto, H.2    Kato, M.3
  • 60
    • 0023255380 scopus 로고
    • Preparation of fluorinated antibiotics followed by F-19-NMR spectroscopy. 4. Fluorinated blasticidin-S
    • A Kawashima H Seto T Ishiyama M Kato K Uchida N Otake 1987 Preparation of fluorinated antibiotics followed by F-19-NMR spectroscopy. 4. Fluorinated blasticidin-S Agric Biol Chem 51 1183 1184
    • (1987) Agric Biol Chem , vol.51 , pp. 1183-1184
    • Kawashima, A.1    Seto, H.2    Ishiyama, T.3    Kato, M.4    Uchida, K.5    Otake, N.6
  • 61
    • 0013851902 scopus 로고
    • Isolation of bacteria able to metabolize fluoroacetate or fluoracetamide
    • M Kelly 1965 Isolation of bacteria able to metabolize fluoroacetate or fluoracetamide Nature 208 809
    • (1965) Nature , vol.208 , pp. 809
    • Kelly, M.1
  • 62
    • 38849174356 scopus 로고    scopus 로고
    • Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: Combining synthetic chemistry and biosynthetic engineering for diversifying natural products
    • J Kennedy 2008 Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products Nat Prod Rep 25 25 34
    • (2008) Nat Prod Rep , vol.25 , pp. 25-34
    • Kennedy, J.1
  • 65
    • 33746372978 scopus 로고    scopus 로고
    • Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules
    • KL Kirk 2006 Fluorine in medicinal chemistry: recent therapeutic applications of fluorinated small molecules J Fluorine Chem 127 1013 1029
    • (2006) J Fluorine Chem , vol.127 , pp. 1013-1029
    • Kirk, K.L.1
  • 66
    • 0017850445 scopus 로고
    • Molecular toxicology of (-)-erythro-fluorocitrate - Selective-inhibition of citrate transport in mitochondria and binding of fluorocitrate to mitochondrial proteins.15
    • E Kirsten ML Sharma E Kun 1978 Molecular toxicology of (-)-erythro-fluorocitrate - selective-inhibition of citrate transport in mitochondria and binding of fluorocitrate to mitochondrial proteins.15 Mol Pharm 14 172 184
    • (1978) Mol Pharm , vol.14 , pp. 172-184
    • Kirsten, E.1    Sharma, M.L.2    Kun, E.3
  • 67
    • 2442471994 scopus 로고    scopus 로고
    • Degradation of 2-fluorophenol by the brown-rot fungus Gloeophyllum striatum: Evidence for the involvement of extracellular Fenton chemistry
    • C Kramer G Kreisel K Fahr J Kassbohrer D Schlosser 2004 Degradation of 2-fluorophenol by the brown-rot fungus Gloeophyllum striatum: evidence for the involvement of extracellular Fenton chemistry Appl Microbiol Biotechnol 64 387 395
    • (2004) Appl Microbiol Biotechnol , vol.64 , pp. 387-395
    • Kramer, C.1    Kreisel, G.2    Fahr, K.3    Kassbohrer, J.4    Schlosser, D.5
  • 68
    • 0042433495 scopus 로고    scopus 로고
    • Purification, characterization, and gene cloning of a novel fluoroacetate dehalogenase from Burkholderia sp FA1
    • T Kurihara T Yamauchi S Ichiyama H Takahata N Esaki 2003 Purification, characterization, and gene cloning of a novel fluoroacetate dehalogenase from Burkholderia sp FA1 J Mol Catal B-Enzym 23 347 355
    • (2003) J Mol Catal B-Enzym , vol.23 , pp. 347-355
    • Kurihara, T.1    Yamauchi, T.2    Ichiyama, S.3    Takahata, H.4    Esaki, N.5
  • 69
    • 0035130401 scopus 로고    scopus 로고
    • Production, isolation and structure determination of novel fluoroindolocarbazoles from Saccharothrix aercolonigenes ATCC 39243
    • KS Lam, et al. 2001 Production, isolation and structure determination of novel fluoroindolocarbazoles from Saccharothrix aercolonigenes ATCC 39243 J Antibiot 54 1 9
    • (2001) J Antibiot , vol.54 , pp. 1-9
    • Lam, K.S.1
  • 70
    • 33746860311 scopus 로고    scopus 로고
    • Special applications of fluorinated organic compounds
    • G Lewandowski E Meissner E Milchert 2006 Special applications of fluorinated organic compounds J Hazard Mater 136 385 391
    • (2006) J Hazard Mater , vol.136 , pp. 385-391
    • Lewandowski, G.1    Meissner, E.2    Milchert, E.3
  • 71
    • 0032553311 scopus 로고    scopus 로고
    • Reaction mechanism of fluoroacetate dehalogenase from Moraxella sp. B
    • JQ Liu, et al. 1998 Reaction mechanism of fluoroacetate dehalogenase from Moraxella sp. B J Biol Chem 273 30897 30902
    • (1998) J Biol Chem , vol.273 , pp. 30897-30902
    • Liu, J.Q.1
  • 72
    • 37049076001 scopus 로고
    • Synthetic approaches towards nucleocidin and selected analogs - Anti-HIV activity in 4′-fluorinated nucleoside derivatives
    • AR Maguire WD Meng SM Roberts AJ Willetts 1993 Synthetic approaches towards nucleocidin and selected analogs - anti-HIV activity in 4′-fluorinated nucleoside derivatives J Chem Soc Perkin Trans 1 1795 1808
    • (1993) J Chem Soc Perkin Trans , vol.1 , pp. 1795-1808
    • Maguire, A.R.1    Meng, W.D.2    Roberts, S.M.3    Willetts, A.J.4
  • 74
    • 0030069422 scopus 로고    scopus 로고
    • Biosynthesis of norsolorinic acid and averufin: Substrate specificity of norsolorinic acid synthase
    • McKeown DSJ, McNicholas C, Simpson TJ, Willett NJ (1996) Biosynthesis of norsolorinic acid and averufin: substrate specificity of norsolorinic acid synthase. Chem Commun 301-302
    • (1996) Chem Commun , pp. 301-302
    • McKeown, D.S.J.1    McNicholas, C.2    Simpson, T.J.3    Willett, N.J.4
  • 75
    • 59849123570 scopus 로고    scopus 로고
    • Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp
    • S Moran DK Rai BR Clark CD Murphy 2009 Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp Org Biomol Chem 7 644 646
    • (2009) Org Biomol Chem , vol.7 , pp. 644-646
    • Moran, S.1    Rai, D.K.2    Clark, B.R.3    Murphy, C.D.4
  • 76
    • 59949088495 scopus 로고    scopus 로고
    • Metabolism of hydroxylated and fluorinated benzoates by Syntrophus aciditrophicus and detection of a fluorodiene metabolite
    • H Mouttaki MA Nanny MJ [tmp] McInerney 2009 Metabolism of hydroxylated and fluorinated benzoates by Syntrophus aciditrophicus and detection of a fluorodiene metabolite Appl Environ Microbiol 75 998 1004
    • (2009) Appl Environ Microbiol , vol.75 , pp. 998-1004
    • Mouttaki, H.1    Nanny, M.A.2    McInerney, M.J.3
  • 77
    • 34648822319 scopus 로고    scopus 로고
    • The application of F-19 nuclear magnetic resonance to investigate microbial biotransformations of organofluorine compounds
    • CD Murphy 2007 The application of F-19 nuclear magnetic resonance to investigate microbial biotransformations of organofluorine compounds Omics 11 314 324
    • (2007) Omics , vol.11 , pp. 314-324
    • Murphy, C.D.1
  • 78
    • 33845632032 scopus 로고    scopus 로고
    • Fluorophenol oxidation by a fungal chloroperoxidase
    • CD Murphy 2007 Fluorophenol oxidation by a fungal chloroperoxidase Biotechnol Lett 29 45 49
    • (2007) Biotechnol Lett , vol.29 , pp. 45-49
    • Murphy, C.D.1
  • 79
    • 47849101635 scopus 로고    scopus 로고
    • Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenes KF707
    • CD Murphy S Quirke O Balogun 2008 Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenes KF707 FEMS Microbiol Lett 286 45 49
    • (2008) FEMS Microbiol Lett , vol.286 , pp. 45-49
    • Murphy, C.D.1    Quirke, S.2    Balogun, O.3
  • 80
    • 31944449518 scopus 로고    scopus 로고
    • C. fumago chloroperoxidase is also a dehaloperoxidase: Oxidative dehalogenation of halophenols
    • RL Osborne GM Raner LP Hager JH Dawson 2006 C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols J Am Chem Soc 128 1036 1037
    • (2006) J Am Chem Soc , vol.128 , pp. 1036-1037
    • Osborne, R.L.1    Raner, G.M.2    Hager, L.P.3    Dawson, J.H.4
  • 83
    • 0035051410 scopus 로고    scopus 로고
    • Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus
    • IA Parshikov, et al. 2001 Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus J Ind Microbiol Biotech 26 140 144
    • (2001) J Ind Microbiol Biotech , vol.26 , pp. 140-144
    • Parshikov, I.A.1
  • 85
    • 0026557370 scopus 로고
    • Analogs of cyclosporin A modified at the D-Ala position
    • AA Patchett, et al. 1992 Analogs of cyclosporin A modified at the D-Ala position J Antibiot 45 94 102
    • (1992) J Antibiot , vol.45 , pp. 94-102
    • Patchett, A.A.1
  • 86
    • 62749133986 scopus 로고    scopus 로고
    • A first global production, emission, and environmental inventory for perfluorooctane sulfonate
    • AG Paul KC Jones AJ Sweetman 2009 A first global production, emission, and environmental inventory for perfluorooctane sulfonate Environ Sci Technol 43 386 392
    • (2009) Environ Sci Technol , vol.43 , pp. 386-392
    • Paul, A.G.1    Jones, K.C.2    Sweetman, A.J.3
  • 87
    • 47149109617 scopus 로고    scopus 로고
    • Synthesis and analytical follow-up of the mineralization of a new fluorosurfactant prototype
    • M Peschka, et al. 2008 Synthesis and analytical follow-up of the mineralization of a new fluorosurfactant prototype Chemosphere 72 1534 1540
    • (2008) Chemosphere , vol.72 , pp. 1534-1540
    • Peschka, M.1
  • 88
    • 77951358085 scopus 로고
    • Biochemistry of fluoroacetate poisoning-the isolation and some properties of the fluorotricarboxylic acid inhibitor of citrate metabolism
    • R Peters RW Wakelin P Buffa LC Thomas 1953 Biochemistry of fluoroacetate poisoning-the isolation and some properties of the fluorotricarboxylic acid inhibitor of citrate metabolism Proc R Soc B-Biol Sci 140 497 507
    • (1953) Proc R Soc B-Biol Sci , vol.140 , pp. 497-507
    • Peters, R.1    Wakelin, R.W.2    Buffa, P.3    Thomas, L.C.4
  • 89
    • 34347263411 scopus 로고    scopus 로고
    • Precursor-directed biosynthesis of nonribosomal lipopeptides with modified glutamate residues
    • DOI 10.1039/b706224a
    • Powell A, Al Nakeeb M, Wilkinson B, Micklefield J (2007) Precursor-directed biosynthesis of nonribosomal lipopeptides with modified glutamate residues. Chem Commun 2683-2685 (Pubitemid 47000805)
    • (2007) Chemical Communications , Issue.26 , pp. 2683-2685
    • Powell, A.1    Al Nakeeb, M.2    Wilkinson, B.3    Micklefield, J.4
  • 90
    • 0035286746 scopus 로고    scopus 로고
    • Fungal metabolism of toluene: Monitoring of fluorinated analogs by F-19 nuclear magnetic resonance spectroscopy
    • FX Prenafeta-Boldu D Luykx J Vervoort JAM de Bont 2001 Fungal metabolism of toluene: monitoring of fluorinated analogs by F-19 nuclear magnetic resonance spectroscopy Appl Environ Microbiol 67 1030 1034
    • (2001) Appl Environ Microbiol , vol.67 , pp. 1030-1034
    • Prenafeta-Boldu, F.X.1    Luykx, D.2    Vervoort, J.3    De Bont, J.A.M.4
  • 92
    • 33745191846 scopus 로고    scopus 로고
    • Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5
    • S Rachid, et al. 2006 Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5 Chem Biol 13 667 681
    • (2006) Chem Biol , vol.13 , pp. 667-681
    • Rachid, S.1
  • 93
    • 65249180102 scopus 로고    scopus 로고
    • Evaluating indole-related derivatives as precursors in the directed biosynthesis of diazepinomicin analogues
    • AS Ratnayake JE Janso X Feng G Schlingmann I Goljer GT Carter 2009 Evaluating indole-related derivatives as precursors in the directed biosynthesis of diazepinomicin analogues J Nat Prod 72 496 499
    • (2009) J Nat Prod , vol.72 , pp. 496-499
    • Ratnayake, A.S.1    Janso, J.E.2    Feng, X.3    Schlingmann, G.4    Goljer, I.5    Carter, G.T.6
  • 94
    • 0030438856 scopus 로고    scopus 로고
    • Biotransformation of halophenols by a thermophilic Bacillus sp
    • UM Reinscheid MP Bauer R Muller 1997 Biotransformation of halophenols by a thermophilic Bacillus sp Biodegradation 7 455 461
    • (1997) Biodegradation , vol.7 , pp. 455-461
    • Reinscheid, U.M.1    Bauer, M.P.2    Muller, R.3
  • 96
    • 0022652498 scopus 로고
    • Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya
    • M Sanada, et al. 1986 Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya J Antibiot 39 259 265
    • (1986) J Antibiot , vol.39 , pp. 259-265
    • Sanada, M.1
  • 97
    • 0021982903 scopus 로고
    • Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria
    • U Schennen K Braun HJ Knackmuss 1985 Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria J Bacteriol 161 321 325
    • (1985) J Bacteriol , vol.161 , pp. 321-325
    • Schennen, U.1    Braun, K.2    Knackmuss, H.J.3
  • 98
    • 0027376920 scopus 로고
    • Biodegradation and transformation of 4, 4′-dihalodiphenyl and 2, 4-dihalodiphenyl ethers by Sphingomonas sp strain ss33
    • S Schmidt P Fortnagel RM Wittich 1993 Biodegradation and transformation of 4, 4′-dihalodiphenyl and 2, 4-dihalodiphenyl ethers by Sphingomonas sp strain ss33 Appl Environ Microbiol 59 3931 3933
    • (1993) Appl Environ Microbiol , vol.59 , pp. 3931-3933
    • Schmidt, S.1    Fortnagel, P.2    Wittich, R.M.3
  • 99
    • 0014663511 scopus 로고
    • Synthesis of adenine 5′-O-sulfamoyl nucleosides related to nucleocidin
    • DA Shuman RK Robins MJ Robins 1969 Synthesis of adenine 5′-O-sulfamoyl nucleosides related to nucleocidin J Am Chem Soc 91 3391 3392
    • (1969) J Am Chem Soc , vol.91 , pp. 3391-3392
    • Shuman, D.A.1    Robins, R.K.2    Robins, M.J.3
  • 103
    • 46649116337 scopus 로고    scopus 로고
    • Highly active ansamitocin derivatives: Mutasynthesis using an AHBA-blocked mutant
    • F Taft, et al. 2008 Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant ChemBioChem 9 1057 1060
    • (2008) ChemBioChem , vol.9 , pp. 1057-1060
    • Taft, F.1
  • 104
    • 2942648245 scopus 로고    scopus 로고
    • Microbial synthesis and characterization of polyhydroxyalkanoates with fluorinated phenoxy side groups from Pseudomonas putida
    • Y Takagi R Yasuda A Maehara T Yamane 2004 Microbial synthesis and characterization of polyhydroxyalkanoates with fluorinated phenoxy side groups from Pseudomonas putida Eur Polym J 40 1551 1557
    • (2004) Eur Polym J , vol.40 , pp. 1551-1557
    • Takagi, Y.1    Yasuda, R.2    Maehara, A.3    Yamane, T.4
  • 105
    • 0029744664 scopus 로고    scopus 로고
    • Precursor directed biosynthesis of aureobasidins
    • K Takesako, et al. 1996 Precursor directed biosynthesis of aureobasidins J Antibiot 49 676 681
    • (1996) J Antibiot , vol.49 , pp. 676-681
    • Takesako, K.1
  • 106
    • 33746611885 scopus 로고    scopus 로고
    • Fluorinated natural products with clinical significance
    • CJ Thomas 2006 Fluorinated natural products with clinical significance Curr Top Med Chem 6 1529 1543
    • (2006) Curr Top Med Chem , vol.6 , pp. 1529-1543
    • Thomas, C.J.1
  • 107
    • 84961016205 scopus 로고
    • Nucleocidin, a new antibiotic with activity against trypanosomes
    • Thomas SO et al (1957) Nucleocidin, a new antibiotic with activity against trypanosomes. Antibiot Ann 716-721
    • (1957) Antibiot Ann , pp. 716-721
    • Thomas, S.O.1
  • 110
    • 0028450629 scopus 로고
    • Degradation of trifluoroacetate in oxic and anoxic sediments
    • PT Visscher CW Culbertson RS Oremland 1994 Degradation of trifluoroacetate in oxic and anoxic sediments Nature 369 729 731
    • (1994) Nature , vol.369 , pp. 729-731
    • Visscher, P.T.1    Culbertson, C.W.2    Oremland, R.S.3
  • 111
    • 0001109771 scopus 로고
    • Metabolism of fluoroacetate by a soil Pseudomonas sp and Fusarium solani
    • JRL Walker BC Lien 1981 Metabolism of fluoroacetate by a soil Pseudomonas sp and Fusarium solani Soil Biol Biochem 13 231 235
    • (1981) Soil Biol Biochem , vol.13 , pp. 231-235
    • Walker, J.R.L.1    Lien, B.C.2
  • 112
    • 33845621530 scopus 로고    scopus 로고
    • Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase
    • SL Ward RP Desai ZH Hu H Gramajo L Katz 2007 Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase J Ind Microbiol Biotechnol 34 9 15
    • (2007) J Ind Microbiol Biotechnol , vol.34 , pp. 9-15
    • Ward, S.L.1    Desai, R.P.2    Hu, Z.H.3    Gramajo, H.4    Katz, L.5
  • 113
    • 0037119714 scopus 로고    scopus 로고
    • Fluorobalhimycin-a new chapter in glycopeptide antibiotic research
    • S Weist, et al. 2002 Fluorobalhimycin-a new chapter in glycopeptide antibiotic research Angew Chem Int Edit 41 3383 3385
    • (2002) Angew Chem Int Edit , vol.41 , pp. 3383-3385
    • Weist, S.1
  • 114
    • 23444460405 scopus 로고    scopus 로고
    • Mutational biosynthesis-a tool for the generation of structural diversity in the biosynthesis of antibiotics
    • S Weist RD Sussmuth 2005 Mutational biosynthesis-a tool for the generation of structural diversity in the biosynthesis of antibiotics Appl Microbiol Biotechnol 68 141 150
    • (2005) Appl Microbiol Biotechnol , vol.68 , pp. 141-150
    • Weist, S.1    Sussmuth, R.D.2
  • 115
    • 0030721747 scopus 로고    scopus 로고
    • Degradation of the fluoroquinolone enrofloxacin by the brown rot fungus Gloeophyllum striatum: Identification of metabolites
    • HG Wetzstein N Schmeer W Karl 1997 Degradation of the fluoroquinolone enrofloxacin by the brown rot fungus Gloeophyllum striatum: identification of metabolites Appl Environ Microbiol 63 4272 4281
    • (1997) Appl Environ Microbiol , vol.63 , pp. 4272-4281
    • Wetzstein, H.G.1    Schmeer, N.2    Karl, W.3
  • 116
    • 0032957077 scopus 로고    scopus 로고
    • Degradation of ciprofloxacin by basidiomycetes and identification of metabolites generated by the brown rot fungus Gloeophyllum striatum
    • HG Wetzstein M Stadler HV Tichy A Dalhoff W Karl 1999 Degradation of ciprofloxacin by basidiomycetes and identification of metabolites generated by the brown rot fungus Gloeophyllum striatum Appl Environ Microbiol 65 1556 1563
    • (1999) Appl Environ Microbiol , vol.65 , pp. 1556-1563
    • Wetzstein, H.G.1    Stadler, M.2    Tichy, H.V.3    Dalhoff, A.4    Karl, W.5
  • 117
    • 33744499951 scopus 로고    scopus 로고
    • Patters of metabolites produced from the fluoroquinolone enrofloxacin in basidiomycetes indigenous to agricultural sites
    • HG Wetzstein J Schneider W Karl 2006 Patters of metabolites produced from the fluoroquinolone enrofloxacin in basidiomycetes indigenous to agricultural sites Appl Microbiol Biotechnol 71 90 100
    • (2006) Appl Microbiol Biotechnol , vol.71 , pp. 90-100
    • Wetzstein, H.G.1    Schneider, J.2    Karl, W.3
  • 118
    • 32644473666 scopus 로고    scopus 로고
    • Natural and directed biosynthesis of communesin alkaloids
    • LJ Wigley PG Mantle DA Perry 2006 Natural and directed biosynthesis of communesin alkaloids Phytochemistry 67 561 569
    • (2006) Phytochemistry , vol.67 , pp. 561-569
    • Wigley, L.J.1    Mantle, P.G.2    Perry, D.A.3
  • 119
    • 0031369263 scopus 로고    scopus 로고
    • Transformation of difluorinated phenols by Penicillium frequentans Bi 7/2
    • U Wunderwald M Hofrichter G Kreisel W Fritsche 1997 Transformation of difluorinated phenols by Penicillium frequentans Bi 7/2 Biodegradation 8 379 385
    • (1997) Biodegradation , vol.8 , pp. 379-385
    • Wunderwald, U.1    Hofrichter, M.2    Kreisel, G.3    Fritsche, W.4
  • 120
    • 22944438036 scopus 로고    scopus 로고
    • Biotransformation of pantoprazole by the fungus Cunninghamella blakesleeana
    • ZY Xie HH Huang DF Zhong 2005 Biotransformation of pantoprazole by the fungus Cunninghamella blakesleeana Xenobiotica 35 467 477
    • (2005) Xenobiotica , vol.35 , pp. 467-477
    • Xie, Z.Y.1    Huang, H.H.2    Zhong, D.F.3
  • 121
    • 35348843398 scopus 로고    scopus 로고
    • Cytotoxic and antihaptotactic beauvericin analogues from precursor-directed biosynthesis with the insect pathogen Beauveria bassiana ATCC 7159
    • Y Xu J Zhan EMK Wijeratne AM Burns AAL Gunatilaka I Molnar 2007 Cytotoxic and antihaptotactic beauvericin analogues from precursor-directed biosynthesis with the insect pathogen Beauveria bassiana ATCC 7159 J Nat Prod 70 1467 1471
    • (2007) J Nat Prod , vol.70 , pp. 1467-1471
    • Xu, Y.1    Zhan, J.2    Wijeratne, E.M.K.3    Burns, A.M.4    Gunatilaka, A.A.L.5    Molnar, I.6
  • 122
    • 0030909863 scopus 로고    scopus 로고
    • Further metabolic studies of indole and sugar derivatives using the staurosporine producer Streptomyces staurosporeus
    • SW Yang GA Cordell 1997 Further metabolic studies of indole and sugar derivatives using the staurosporine producer Streptomyces staurosporeus J Nat Prod 60 230 235
    • (1997) J Nat Prod , vol.60 , pp. 230-235
    • Yang, S.W.1    Cordell, G.A.2
  • 123
    • 0031024036 scopus 로고    scopus 로고
    • Metabolism studies of indole derivatives using a staurosporine producer, Streptomyces staurosporeus
    • SW Yang GA Cordell 1997 Metabolism studies of indole derivatives using a staurosporine producer, Streptomyces staurosporeus J Na Prod 60 44 48
    • (1997) J Na Prod , vol.60 , pp. 44-48
    • Yang, S.W.1    Cordell, G.A.2
  • 124
    • 0029945423 scopus 로고    scopus 로고
    • Phase i and phase II enzymes produced by Cunninghamella elegans for the metabolism of xenobiotics
    • DL Zhang YF Yang JEA Leakey CE Cerniglia 1996 Phase I and phase II enzymes produced by Cunninghamella elegans for the metabolism of xenobiotics FEMS Microbiol Lett 138 221 226
    • (1996) FEMS Microbiol Lett , vol.138 , pp. 221-226
    • Zhang, D.L.1    Yang, Y.F.2    Leakey, J.E.A.3    Cerniglia, C.E.4


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