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Volumn 8, Issue 17, 2009, Pages 2844-2849

HIF-1 prevents the overproduction of mitochondrial ROS after cytokine stimulation through induction of PDK-1

Author keywords

Glucose; HIF 1; Mitochondria; PDK 1; ROS; TPO

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; PROTEIN KINASE; PYRUVATE DEHYDROGENASE KINASE 1; REACTIVE OXYGEN METABOLITE; THROMBOPOIETIN; UNCLASSIFIED DRUG;

EID: 69749117834     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.17.9544     Document Type: Article
Times cited : (53)

References (25)
  • 1
    • 53349091768 scopus 로고    scopus 로고
    • TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
    • Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, et al. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 2008; 205:2397-2408
    • (2008) J Exp Med , vol.205 , pp. 2397-2408
    • Chen, C.1    Liu, Y.2    Liu, R.3    Ikenoue, T.4    Guan, K.L.5    Liu, Y.6
  • 3
    • 33344461473 scopus 로고    scopus 로고
    • G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth
    • DOI 10.1182/blood-2005-04-1612
    • Zhu QS, Xia L, Mills GB, Lowell CA, Touw IP, Corey SJ. G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth. Blood 2006; 107:1847-1856 (Pubitemid 43289362)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1847-1856
    • Zhu, Q.-S.1    Xia, L.2    Mills, G.B.3    Lowell, C.A.4    Touw, I.P.5    Corey, S.J.6
  • 4
    • 0033135256 scopus 로고    scopus 로고
    • Hematopoietic growth factors signal through the formation of reactive oxygen species
    • Sattler M, Winkler T, Verma S, Byrne CH, Shrikhande G, Salgia R, et al. Hematopoietic growth factors signal through the formation of reactive oxygen species. Blood 1999; 93:2928-2935 (Pubitemid 29200783)
    • (1999) Blood , vol.93 , Issue.9 , pp. 2928-2935
    • Sattler, M.1    Winkler, T.2    Verma, S.3    Byrne, C.H.4    Shrikhande, G.5    Salgia, R.6    Griffin, J.D.7
  • 5
    • 27344448624 scopus 로고    scopus 로고
    • Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression
    • DOI 10.1016/j.cellsig.2005.04.002, PII S0898656805000793
    • Iiyama M, Kakihana K, Kurosu T, Miura O. Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression. Cell Signal 2006; 18:174-182 (Pubitemid 41527161)
    • (2006) Cellular Signalling , vol.18 , Issue.2 , pp. 174-182
    • Iiyama, M.1    Kakihana, K.2    Kurosu, T.3    Miura, O.4
  • 6
    • 56749105854 scopus 로고    scopus 로고
    • Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species
    • Yoshida K, Kirito K, Yongzhen H, Ozawa K, Kaushansky K, Komatsu N. Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species. Int J Hematol 2008; 88:43-51.
    • (2008) Int J Hematol , vol.88 , pp. 43-51
    • Yoshida, K.1    Kirito, K.2    Yongzhen, H.3    Ozawa, K.4    Kaushansky, K.5    Komatsu, N.6
  • 7
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • DOI 10.1016/j.cmet.2006.02.002, PII S1550413106000623
    • Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006; 3:177-185 (Pubitemid 43316523)
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 177-185
    • Kim, J.-W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 8
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • DOI 10.1016/j.cmet.2006.01.012, PII S155041310600060X
    • Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006; 3:187-197 (Pubitemid 43316524)
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 12
    • 53049103850 scopus 로고    scopus 로고
    • Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
    • Michelakis ED, Webster L, Mackey JR. Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer. Br J Cancer 2008; 99:989-994
    • (2008) Br J Cancer , vol.99 , pp. 989-994
    • Michelakis, E.D.1    Webster, L.2    Mackey, J.R.3
  • 13
    • 6344227760 scopus 로고    scopus 로고
    • Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand
    • Bauer DE, Harris MH, Plas DR, Lum JJ, Hammerman PS, Rathmell JC, et al. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. Faseb J 2004; 18:1303-1305
    • (2004) Faseb J , vol.18 , pp. 1303-1305
    • Bauer, D.E.1    Harris, M.H.2    Plas, D.R.3    Lum, J.J.4    Hammerman, P.S.5    Rathmell, J.C.6
  • 15
    • 50149097983 scopus 로고    scopus 로고
    • Hypoxia, HIF1 and glucose metabolism in the solid tumour
    • Denko NC. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nature Rev 2008; 8:705-713
    • (2008) Nature Rev , vol.8 , pp. 705-713
    • Denko, N.C.1
  • 16
    • 33947724515 scopus 로고    scopus 로고
    • HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
    • DOI 10.1016/j.cell.2007.01.047, PII S0092867407003078
    • Fukuda R, Zhang H, Kim JW, Shimoda L, Dang CV, Semenza GL. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 2007; 129:111-122 (Pubitemid 46507584)
    • (2007) Cell , vol.129 , Issue.1 , pp. 111-122
    • Fukuda, R.1    Zhang, H.2    Kim, J.-W.3    Shimoda, L.4    Dang, C.V.5    Semenza, G.6
  • 17
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
    • DOI 10.1016/j.ccr.2007.04.001, PII S1535610807001158
    • Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI, et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 2007; 11:407-420 (Pubitemid 46670080)
    • (2007) Cancer Cell , vol.11 , Issue.5 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6    Dang, C.7    Semenza, G.L.8
  • 18
    • 43649104579 scopus 로고    scopus 로고
    • Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
    • Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 2008; 283:10892-10903
    • (2008) J Biol Chem , vol.283 , pp. 10892-10903
    • Zhang, H.1    Bosch-Marce, M.2    Shimoda, L.A.3    Tan, Y.S.4    Baek, J.H.5    Wesley, J.B.6
  • 19
    • 34247631690 scopus 로고    scopus 로고
    • The transcription factor HIF-1 plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
    • DOI 10.1101/gad.1529107
    • Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, et al. The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev 2007; 21:1037-1049 (Pubitemid 46686473)
    • (2007) Genes and Development , vol.21 , Issue.9 , pp. 1037-1049
    • Lum, J.J.1    Bui, T.2    Gruber, M.3    Gordan, J.D.4    Deberardinis, R.J.5    Covello, K.L.6    Simon, M.C.7    Thompson, C.B.8
  • 20
    • 35548936968 scopus 로고    scopus 로고
    • A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    • Jang YY, Sharkis SJ. A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 2007; 110:3056-3063
    • (2007) Blood , vol.110 , pp. 3056-3063
    • Jang, Y.Y.1    Sharkis, S.J.2
  • 21
    • 42449145174 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: Implications for poor prognosis in AML
    • Sallmyr A, Fan J, Datta K, Kim KT, Grosu D, Shapiro P, et al. Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML. Blood 2008; 111:3173-3182
    • (2008) Blood , vol.111 , pp. 3173-3182
    • Sallmyr, A.1    Fan, J.2    Datta, K.3    Kim, K.T.4    Grosu, D.5    Shapiro, P.6
  • 23
    • 57649130593 scopus 로고    scopus 로고
    • Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance
    • Lu CW, Lin SC, Chen KF, Lai YY, Tsai SJ. Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance. J Biol Chem 2008; 283:28106-28114
    • (2008) J Biol Chem , vol.283 , pp. 28106-28114
    • Lu, C.W.1    Lin, S.C.2    Chen, K.F.3    Lai, Y.Y.4    Tsai, S.J.5
  • 24
    • 17844408765 scopus 로고    scopus 로고
    • Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1alpha
    • DOI 10.1182/blood-2004-07-2712
    • Kirito K, Fox N, Komatsu N, Kaushansky K. Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1alpha. Blood 2005; 105:4258-4263 (Pubitemid 40720771)
    • (2005) Blood , vol.105 , Issue.11 , pp. 4258-4263
    • Kirito, K.1    Fox, N.2    Komatsu, N.3    Kaushansky, K.4
  • 25
    • 1642329821 scopus 로고    scopus 로고
    • Hypoxia-Inducible Factor-1-Independent Regulation of Vascular Endothelial Growth Factor by Hypoxia in Colon Cancer
    • DOI 10.1158/0008-5472.CAN-03-3017
    • Mizukami Y, Li J, Zhang X, Zimmer MA, Iliopoulos O, Chung DC. Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer. Cancer Res 2004; 64:1765-1772 (Pubitemid 38428700)
    • (2004) Cancer Research , vol.64 , Issue.5 , pp. 1765-1772
    • Mizukami, Y.1    Li, J.2    Zhang, X.3    Zimmer, M.A.4    Iliopoulos, O.5    Chung, D.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.