N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: Interaction with α4β2* and α7* Neuronal nicotinic receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 304, Issue 1, 2003, Pages 400-410

  Wilkins Jr , Lincoln H ^a   Grinevich, Vladimir P ^a,b   Ayers, Joshua T ^a,c   Crooks, Peter A ^a   Dwoskin, Linda P ^a  

^a University of Kentucky   (United States)

^b TARGACEPT INC   (United States)

^c ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; N BUTYLNICOTINIUM IODIDE; N DECYLNICOTINIUM IODIDE; N DODECYLNICOTINIUM IODIDE; N ETHYLNICOTINIUM IODIDE; N HEPTYLNICOTINIUM IODIDE; N HEXYLNICOTINIUM IODIDE; N METHYLNICOTINIUM IODIDE; N NONYLNICOTINIUM IODIDE; N OCTYLNICOTINIUM IODIDE; N PENTYLNICOTINIUM IODIDE; N PROPYLNICOTINIUM IODIDE; N UNDECYLNICOTINIUM IODIDE; NICOTINE DERIVATIVE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG ANTAGONISM; DRUG INHIBITION; DRUG SELECTIVITY; MALE; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; STRIATE CORTEX;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BRAIN; DIHYDRO-BETA-ERYTHROIDINE; DOPAMINE; KINETICS; MALE; MEMBRANES; NEOSTRIATUM; NEURONS; NICOTINE; NICOTINIC ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037214393     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.043349     Document Type: Article

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