Biological significance of DNA adducts investigated by simultaneous analysis of different endpoints of genotoxicity in L5178Y mouse lymphoma cells treated with methyl methanesulfonate

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 625, Issue 1-2, 2007, Pages 94-101

  Brink, Andreas ^a   Schulz, Berta ^a   Stopper, Helga ^a   Lutz, Werner K ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

7 Methylguanine; Background and increment; Comet assay; DNA damage; Dose response relationships; Micronucleus test; O6 Methyl 2 deoxyguanosine; Risk assessment

Indexed keywords

MESYLIC ACID METHYL ESTER; XENOBIOTIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA ADDUCT; DNA METHYLATION; DOSE RESPONSE; GENOTOXICITY; LYMPHOMA CELL; MICRONUCLEUS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; DNA BREAKS; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE; LEUKEMIA L5178; METHYL METHANESULFONATE; MICE; MODELS, BIOLOGICAL; MUTAGENS; TANDEM MASS SPECTROMETRY;

EID: 35548947522     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.05.007     Document Type: Article

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