Formation of endothelial lumens requires a coordinated PKCε-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation

Journal of Cell Science

Volumn 122, Issue 11, 2009, Pages 1812-1822

  Koh, Wonshill ^a   Sachidanandam, Kamakshi ^a   Stratman, Amber N ^a   Sacharidou, Anastasia ^a   Mayo, Anne M ^a   Murphy, Eric A ^b   Cheresh, David A ^b   Davis, George E ^a,c  

^a UNIVERSITY OF MISSOURI   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c University of Missouri   (United States)

Author keywords

Cdc42; Extracellular matrix; Lumen formation; Pak; PKC ; Raf; Rho GTPases; Src

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; P21 ACTIVATED KINASE; P21 ACTIVATED KINASE 2; P21 ACTIVATED KINASE 4; PROTEIN CDC42; PROTEIN KINASE C EPSILON; PROTEIN TYROSINE KINASE; RAF PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MEMBRANE FORMATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

CDC42 GTP-BINDING PROTEIN; CELLS, CULTURED; COLLAGEN; ENDOTHELIAL CELLS; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; ISOENZYMES; MULTIPROTEIN COMPLEXES; P21-ACTIVATED KINASES; PROTEIN KINASE C-EPSILON; RAF KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TISSUE CULTURE TECHNIQUES; TISSUE SCAFFOLDS;

EID: 69449102133     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.045799     Document Type: Article

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