AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats

Neurochemistry International

Volumn 55, Issue 7, 2009, Pages 529-535

  Kanemaru, Kazuya ^a   Nishi, Kyoko ^a   Diksic, Mirko ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Autoradiography; Serotonin; Synthesis; Tracer; Tryptophan hydroxylase activation inhibitor

Indexed keywords

3 (3 DIMETHYLAMINOPROPYL) 3 (3 METHOXYPHENYL) 4,4 DIMETHYL 2,6 PIPERIDINEDIONE; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DEPRESSION; DISEASE MODEL; ENZYME INHIBITION; EXPERIMENTAL RAT; FLINDERS RESISTANT LINE RAT; FLINDERS SENSITIVE LINE RAT; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN METABOLISM;

ANIMALS; AUTORADIOGRAPHY; BRAIN CHEMISTRY; DEPRESSION; ENZYME ACTIVATION; LINEAR MODELS; PIPERIDONES; RATS; SEROTONIN; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE;

ANIMALIA; RATTUS;

EID: 69349092307     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.05.008     Document Type: Article

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