Synthesis of a novel series of imidazo[1,2-α]pyridines as acyl-CoA: Cholesterol acyltransferase (ACAT) inhibitors

Bulletin of the Korean Chemical Society

Volumn 30, Issue 6, 2009, Pages 1297-1304

  Jin, Yinglan ^a   Rho, Mun Chual ^b   Gajulapati, Kondaji ^c   Jung, Hwa Young ^c   Boovanahalli, Shanthaveerappa K ^a   Lee, Jee Hyun ^d   Song, Gyu Yong ^d   Choi, Jung Ho ^a   Kim, Young Kook ^a   Lee, Kyeong ^a   Choi, Yongseok ^c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology   (South Korea)

^c Korea University   (South Korea)

^d Chungnam National University   (South Korea)

Author keywords

Acyl CoA: cholestrol acyl transferase (ACAT); HepG2 cells; Imidazo 1,2 pyridines; Structure activity relationship

Indexed keywords

ACYL COA: CHOLESTROL ACYL TRANSFERASE (ACAT); ACYL-COA:CHOLESTEROL ACYLTRANSFERASE; CHOLESTERYL ESTERS; HEPG2 CELLS; INHIBITORY ACTIVITY; LEAD OPTIMIZATION; NOVEL SERIES; POTENT INHIBITION; STRUCTURE-ACTIVITY RELATIONSHIP;

CHOLESTEROL; ENZYMES; ESTERS; LEAD COMPOUNDS; SYNTHESIS (CHEMICAL);

PYRIDINE;

EID: 69249186403     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2009.30.6.1297     Document Type: Article

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