Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl-CoA:cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 18, 2004, Pages 4677-4681

  Lee, Sangku ^a   Han, Jong Min ^a   Kim, Hyunjung ^a   Kim, Eungsoo ^a   Jeong, Tae Sook ^a   Lee, Woo Song ^a   Cho, Kyung Hyun ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIHYDROXYHYDROCINNAMIC ACID(ASPARTIC ACID DIBENZYL ESTER)AMIDE; 4 HYDROXYCINNAMIC ACID(PHENYLALANINE METHYL ESTER)AMIDE; 4 HYDROXYCOUMARIN DERIVATIVE; CHOLESTEROL ACYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; MOUSE; NONHUMAN; OXIDATION; PARTICLE SIZE; REACTION ANALYSIS;

ALANINE; ANIMALS; ANTIOXIDANTS; ASPARTIC ACID; CELL LINE; CELL SURVIVAL; CINNAMATES; ELECTROPHORESIS, AGAR GEL; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; MICE; PHENYLALANINE; RATS; STEROL O-ACYLTRANSFERASE; STRUCTURE-ACTIVITY RELATIONSHIP; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS;

EID: 8544221890     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.101     Document Type: Article

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