Antimalarials: Synthesis of 4-Aminoquinolines that Circumvent Drug Resistance in Malaria Parasites [1]

Journal of Heterocyclic Chemistry

Volumn 34, Issue 1, 1997, Pages 315-320

  De, Dibyendu ^a   Byers, Larry D ^a   Krogstad, Donald J ^a,b  

^a TULANE UNIVERSITY   (United States)

^b TULANE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT; CHLOROQUINE;

ARTICLE; DRUG RESISTANCE; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; PLASMODIUM FALCIPARUM; REACTION ANALYSIS;

EID: 0030888848     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570340149     Document Type: Article

References (25)

1. Presented in part, 211th ACS Meeting, New Orleans LA, March 24, 1996, Medicinal Abstract No. 18, 210th ACS Meeting, Chicago IL, August 20, 1995, Medicinal Abstract No. 215.
2. Presented in part, 211th ACS Meeting, New Orleans LA, March 24, 1996, Medicinal Abstract No. 18, 210th ACS Meeting, Chicago IL, August 20, 1995, Medicinal Abstract No. 215.
3. WHO, Wkly. Epidem. Rec., 69, 309 (1994); S. C. Oaks Jr., V. S. Mitchell, and G. W. Pearson, Malaria: Obstacles and Opportunities, Institute of Medicine, Washington, DC, 1991.
4. WHO, Wkly. Epidem. Rec., 69, 309 (1994); S. C. Oaks Jr., V. S. Mitchell, and G. W. Pearson, Malaria: Obstacles and Opportunities, Institute of Medicine, Washington, DC, 1991.
5. P. B. Boland, E. M. Lackritz, P. N. Kazembe, J. B. O. Were, R. Steketee, and C. C. Campbell, J. Infect. Dis., 167, 932 (1993).
6. K. E. Kinnamon and W. E. Rothe, Am. J. Trop. Med. Hyg., 24, 174 (1975).
7. T. G. Geary and J. B. Jensen, J. Parasitol., 69, 97 (1983).
8. D. De, F. M. Krogstad, F. B. Cogswell, and D. J. Krogstad, Am. J. Trop. Med. Hyg., (in press).
9. [7a] C. C. Price and R. M. Roberts, J. Am. Chem. Soc., 68, 1204 (1946);
10. [b] A. R. Surrey, and H. F. Hammer, J. Am. Chem. Soc., 68, 113 (1946).
11. [8a] N. L. Drake, H. J. Creech, J. A. Garman, S. T. Haywood, R. M. Peck, J. O. Van Hook, and E. Walton, J. Am. Chem. Soc., 68, 1208 (1946);
12. [b] D. S. Tarbell, J. Am. Chem. Soc., 68, 1277 (1946).
13. D. De, M. Seth, S. K. Puri, S. K. Chandra, and A. P. Bhaduri, European Patent EP 562185 A1 (1994); Chem. Abstr., 120, 106757 (1994).
14. [10a] A. M. Spivey and F. H. S. Curd, J. Chem. Soc., 2656 (1949);
15. [b] C. C. Price, N. J. Leonard, and R. H. Rtsema, J. Am. Chem. Soc., 68, 1256 (1946);
16. [c] E. A. Steck, L. L. Hallock, A. J. Holland, and L. T. Fletcher, J. Am. Chem. Soc., 70, 1012 (1948).
17. [11a] E. A. Steck, L. L. Hallock, and A. J. Holland, J. Am. Chem. Soc., 68, 129 (1946);
18. [b] E. A. Steck, L. T. Fletcher, J. Am. Chem. Soc., 81, 129 (1959);
19. [c] D. S. Breslow, M. S. Bloom, J. C. Shivers, J. T. Adams, M. J. Weiss, R. S. Yost, and C. R. Hauser, J. Am. Chem. Soc., 68, 1232 (1946).
20. A. R. Surrey, and R. A. Cutler, J. Am. Chem. Soc., 63, 2623 (1951).
21. R. M. Peck, R. K. Preston, and H. J. Creech, J. Am. Chem. Soc., 81, 3984 (1959).
22. [14a] P. Marchini, G. Liso, A. Reho, F. Liberatore, and F. M. Moracci, J. Org. Chem., 40, 3453 (1975);
23. [b] G. W. Gribble, J. M. Jasinski, J. T. Pellicone, and J. A. Panetta, Synthesis, 766 (1978).
24. G. W. Gribble, P. D. Lord, J. Skotnicki, S. E. Dietz, J. T. Eaton, and J. L. Johnson, J. Am. Chem. Soc., 96, 7812 (1974).
25. F. B. Cogswell, J. Preslan, J. P. Spurlock, P. A. Mack, F. M. Krogstad, D. De, W. J. George, and D. J. Krogstad, 44th Am. Soc. Trop. Med. Hyg. Annual Meeting, San Antonio TX, November 21, 1995, Abstract No. 594.