-
1
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
Amador-Ortiz C., Lin W. L., Ahmed Z., Personett D., Davies P., Duara R., Graff-Radford N.R., Hutton M.L. and Dickson D.W. (2007). TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann. Neurol. 61, 435-445.
-
(2007)
Ann. Neurol
, vol.61
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
2
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T., Hasegawa M., Akiyama H., Ikeda K., Nonaka T., Mori H., Mann D., Tsuchiya K., Yoshida M., Hashizume Y. and Oda T. (2006). TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys Res. Commun. 351, 602-611.
-
(2006)
Biochem. Biophys Res. Commun
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
3
-
-
59549094064
-
Structural determinants of the cellular localization and shuttling of TDP-43
-
Ayala Y.M., Zago P., D'Ambrogio A., Xu Y.F., Petrucelli L., Buratti E. and Baralle F.E. (2008). Structural determinants of the cellular localization and shuttling of TDP-43. J. Cell Sci. 121, 3778-3785.
-
(2008)
J. Cell Sci
, vol.121
, pp. 3778-3785
-
-
Ayala, Y.M.1
Zago, P.2
D'Ambrogio, A.3
Xu, Y.F.4
Petrucelli, L.5
Buratti, E.6
Baralle, F.E.7
-
4
-
-
0035965309
-
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
-
Buratti E. and Baralle F.E. (2001). Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9. J. Biol. Chem. 276, 36337-36343.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 36337-36343
-
-
Buratti, E.1
Baralle, F.E.2
-
5
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
Buratti E. and Baralle F.E. (2008). Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front. Biosci. 13, 867-878.
-
(2008)
Front. Biosci
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
6
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti E., Brindisi A., Giombi M., Tisminetzky S., Ayala Y.M. and Baralle F.E. (2005). TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J. Biol. Chem. 280, 37572-37584.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
Baralle, F.E.6
-
7
-
-
0021867285
-
Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with Hirano bodies
-
Cartier L., Galvez S. and Gajdusek D.C. (1985). Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with Hirano bodies. J. Neurol. Neurosurg. Psychiatry 48, 234-238.
-
(1985)
J. Neurol. Neurosurg. Psychiatry
, vol.48
, pp. 234-238
-
-
Cartier, L.1
Galvez, S.2
Gajdusek, D.C.3
-
8
-
-
0036890486
-
Alzheimer's and prion diseases: Distinct pathologies, common proteolytic denominators
-
Checler F. and Vincent B. (2002). Alzheimer's and prion diseases: distinct pathologies, common proteolytic denominators. Trends Neurosci. 25, 616-620.
-
(2002)
Trends Neurosci
, vol.25
, pp. 616-620
-
-
Checler, F.1
Vincent, B.2
-
9
-
-
34250832784
-
Calpain-cleavage of alpha-synuclein: Connecting proteolytic processing to disease-linked aggregation
-
Dufty B.M., Warner L.R., Hou S.T., Jiang S.X., Gomez-Isla T., Leenhouts K.M., Oxford J.T., Feany M.B., Masliah E. and Rohn T.T. (2007). Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. Am. J. Pathol. 170, 1725-1738.
-
(2007)
Am. J. Pathol
, vol.170
, pp. 1725-1738
-
-
Dufty, B.M.1
Warner, L.R.2
Hou, S.T.3
Jiang, S.X.4
Gomez-Isla, T.5
Leenhouts, K.M.6
Oxford, J.T.7
Feany, M.B.8
Masliah, E.9
Rohn, T.T.10
-
10
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior P. and Salvesen G.S. (2004). The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 384, 201-232.
-
(2004)
Biochem. J
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
11
-
-
0023132179
-
Hirano body filaments contain actin and actin-associated proteins
-
Galloway P.G., Perry G. and Gambetti P. (1987). Hirano body filaments contain actin and actin-associated proteins. J. Neuropathol. Exp. Neurol. 46, 185-199.
-
(1987)
J. Neuropathol. Exp. Neurol
, vol.46
, pp. 185-199
-
-
Galloway, P.G.1
Perry, G.2
Gambetti, P.3
-
13
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
Gamblin T.C., Chen F., Zambrano A., Abraha A., Lagalwar S., Guillozet A.L., Lu M., Fu Y., Garcia-Sierra F., LaPointe N., Miller R., Berry R.W., Binder L.I. and Cryns V.L. (2003). Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc. Natl. Acad. Sci USA 100, 10032-10037.
-
(2003)
Proc. Natl. Acad. Sci USA
, vol.100
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
Lapointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
14
-
-
0017642031
-
Numbers of Hirano bodies in the hippocampus of normal and demented people with Alzheimer's disease
-
Gibson P.H. and Tomlinson B.E. (1977). Numbers of Hirano bodies in the hippocampus of normal and demented people with Alzheimer's disease. J. Neurol. Sci. 33, 199-206.
-
(1977)
J. Neurol. Sci
, vol.33
, pp. 199-206
-
-
Gibson, P.H.1
Tomlinson, B.E.2
-
15
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa M., Arai T., Nonaka T., Kametani F., Yoshida M., Hashizume Y., Beach T.G., Buratti E., Baralle F., Morita M., Nakano I., Oda T., Tsuchiya K. and Akiyama H. (2008). Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann. Neurol. 64, 60-70.
-
(2008)
Ann. Neurol
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
Kametani, F.4
Yoshida, M.5
Hashizume, Y.6
Beach, T.G.7
Buratti, E.8
Baralle, F.9
Morita, M.10
Nakano, I.11
Oda, T.12
Tsuchiya, K.13
Akiyama, H.14
-
16
-
-
0028286860
-
Hirano bodies and related neuronal inclusions
-
Hirano A. (1994). Hirano bodies and related neuronal inclusions. Neuropathol. Appl. Neurobiol. 20, 3-11.
-
(1994)
Neuropathol. Appl. Neurobiol
, vol.20
, pp. 3-11
-
-
Hirano, A.1
-
17
-
-
0014276827
-
The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies and rod-like structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex
-
Hirano A., Dembitzer H.M., Kurland L.T. and Zimmerman H.M. (1968). The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies and rod-like structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex. J. Neuropathol. Exp. Neurol. 27, 167-182.
-
(1968)
J. Neuropathol. Exp. Neurol
, vol.27
, pp. 167-182
-
-
Hirano, A.1
Dembitzer, H.M.2
Kurland, L.T.3
Zimmerman, H.M.4
-
18
-
-
46749138739
-
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Igaz L.M., Kwong L.K., Xu Y., Truax A.C., Uryu K., Neumann M., Clark C.M., Elman L.B., Miller B.L., Grossman M., McCluskey L.F., Trojanowski J.Q. and Lee V.M. (2008). Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am. J. Pathol. 173, 182-194.
-
(2008)
Am. J. Pathol
, vol.173
, pp. 182-194
-
-
Igaz, L.M.1
Kwong, L.K.2
Xu, Y.3
Truax, A.C.4
Uryu, K.5
Neumann, M.6
Clark, C.M.7
Elman, L.B.8
Miller, B.L.9
Grossman, M.10
McCluskey, L.F.11
Trojanowski, J.Q.12
Lee, V.M.13
-
19
-
-
48749088629
-
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
-
Inukai Y., Nonaka T., Arai T., Yoshida M., Hashizume Y., Beach T.G., Buratti E., Baralle F.E., Akiyama H., Hisanaga S. and Hasegawa M. (2008). Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. FEBS Lett. 582, 2899-2904.
-
(2008)
FEBS Lett
, vol.582
, pp. 2899-2904
-
-
Inukai, Y.1
Nonaka, T.2
Arai, T.3
Yoshida, M.4
Hashizume, Y.5
Beach, T.G.6
Buratti, E.7
Baralle, F.E.8
Akiyama, H.9
Hisanaga, S.10
Hasegawa, M.11
-
20
-
-
44049097065
-
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
-
Johnson B.S., McCaffery J.M., Lindquist S. and Gitler A.D. (2008). A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proc. Natl. Acad. Sci. USA 105, 6439-6444.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6439-6444
-
-
Johnson, B.S.1
McCaffery, J.M.2
Lindquist, S.3
Gitler, A.D.4
-
21
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi E., Valdmanis P.N., Dion P., Spiegelman D., McConkey B.J., Vande Velde C., Bouchard J.P., Lacomblez L., Pochigaeva K., Salachas F., Pradat P.F., Camu W., Meininger V., Dupre N. and Rouleau G.A. (2008). TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat. Genet. 40, 572-574.
-
(2008)
Nat. Genet
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
van de Velde, C.6
Bouchard, J.P.7
Lacomblez, L.8
Pochigaeva, K.9
Salachas, F.10
Pradat, P.F.11
Camu, W.12
Meininger, V.13
Dupre, N.14
Rouleau, G.A.15
-
22
-
-
34447103093
-
TDP-43 proteinopathy: The neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease
-
Kwong L.K., Neumann M., Sampathu D.M., Lee V.M. and Trojanowski J.Q. (2007). TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease. Acta Neuropathol. 114, 63-70.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 63-70
-
-
Kwong, L.K.1
Neumann, M.2
Sampathu, D.M.3
Lee, V.M.4
Trojanowski, J.Q.5
-
23
-
-
20744442130
-
A precipitating role for truncated alphasynuclein and the proteasome in alpha-synuclein aggregation: Implications for pathogenesis of Parkinson's disease
-
Liu C.W., Giasson B.I., Lewis K.A., Lee V.M., Demartino G.N. and Thomas P.J. (2005). A precipitating role for truncated alphasynuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson's disease. J. Biol. Chem. 280, 22670-22678.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 22670-22678
-
-
Liu, C.W.1
Giasson, B.I.2
Lewis, K.A.3
Lee, V.M.4
Demartino, G.N.5
Thomas, P.J.6
-
24
-
-
0028803993
-
Two actin binding proteins, actin depolymerizing factor and cofilin, are associated with Hirano bodies
-
Maciver S.K. and Harrington C.R. (1995). Two actin binding proteins, actin depolymerizing factor and cofilin, are associated with Hirano bodies. Neuroreport 6, 1985-1988.
-
(1995)
Neuroreport
, vol.6
, pp. 1985-1988
-
-
Maciver, S.K.1
Harrington, C.R.2
-
25
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., Chou T.T., Bruce J., Schuck T., Grossman M., Clark C.M., McCluskey L.F., Miller B.L., Masliah E., Mackenzie I.R., Feldman H., Feiden W., Kretzschmar H.A., Trojanowski J.Q. and Lee V.M. (2006). Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
26
-
-
0029066110
-
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
-
Ou S.H., Wu F., Harrich D., Garcia-Martinez L.F. and Gaynor R.B. (1995). Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J. Virol. 69, 3584-3596.
-
(1995)
J. Virol
, vol.69
, pp. 3584-3596
-
-
Ou, S.H.1
Wu, F.2
Harrich, D.3
Garcia-Martinez, L.F.4
Gaynor, R.B.5
-
27
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl S.J. and Shi Y. (2004). Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell. Biol. 5, 897-907.
-
(2004)
Nat. Rev. Mol. Cell. Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
28
-
-
3242749074
-
Caspasecleavage of tau is an early event in Alzheimer disease tangle pathology
-
Rissman R.A., Poon W.W., Blurton-Jones M., Oddo S., Torp R., Vitek M.P., LaFerla F.M., Rohn T.T. and Cotman C.W. (2004). Caspasecleavage of tau is an early event in Alzheimer disease tangle pathology. J. Clin. Invest. 114, 121-130.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 121-130
-
-
Rissman, R.A.1
Poon, W.W.2
Blurton-Jones, M.3
Oddo, S.4
Torp, R.5
Vitek, M.P.6
Laferla, F.M.7
Rohn, T.T.8
Cotman, C.W.9
-
29
-
-
49349104833
-
Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease
-
Rohn T.T. (2008). Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease. Brain Res. 1228, 189-198.
-
(2008)
Brain Res
, vol.1228
, pp. 189-198
-
-
Rohn, T.T.1
-
32
-
-
52949094629
-
Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis
-
Rutherford N.J., Zhang Y.J., Baker M., Gass J.M., Finch N.A., Xu Y.F., Stewart H., Kelley B.J., Kuntz K., Crook R.J., Sreedharan J., Vance C., Sorenson E., Lippa C., Bigio E.H., Geschwind D.H., Knopman D.S., Mitsumoto H., Petersen R.C., Cashman N.R., Hutton M., Shaw C.E., Boylan K.B., Boeve B., Graff-Radford N.R., Wszolek Z.K., Caselli R.J., Dickson D.W., Mackenzie I.R., Petrucelli L. and Rademakers R. (2008). Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. PLoS Genet. 4, e1000193.
-
(2008)
PLoS Genet
, vol.4
-
-
Rutherford, N.J.1
Zhang, Y.J.2
Baker, M.3
Gass, J.M.4
Finch, N.A.5
Xu, Y.F.6
Stewart, H.7
Kelley, B.J.8
Kuntz, K.9
Crook, R.J.10
Sreedharan, J.11
Vance, C.12
Sorenson, E.13
Lippa, C.14
Bigio, E.H.15
Geschwind, D.H.16
Knopman, D.S.17
Mitsumoto, H.18
Petersen, R.C.19
Cashman, N.R.20
Hutton, M.21
Shaw, C.E.22
Boylan, K.B.23
Boeve, B.24
Graff-Radford, N.R.25
Wszolek, Z.K.26
Caselli, R.J.27
Dickson, D.W.28
Mackenzie, I.R.29
Petrucelli, L.30
Rademakers, R.31
more..
-
33
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Sreedharan J., Blair I.P., Tripathi V.B., Hu X., Vance C., Rogelj B., Ackerley S., Durnall J.C., Williams K.L., Buratti E., Baralle F., de Belleroche J., Mitchell J.D., Leigh P.N., Al-Chalabi A., Miller C.C., Nicholson G. and Shaw C.E. (2008). TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 319, 1668-1672.
-
(2008)
Science
, vol.319
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
de Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
34
-
-
42449163952
-
TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
-
Wang I.F., Wu L.S., Chang H.Y. and Shen C.K. (2008). TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor. J. Neurochem. 105, 797-806.
-
(2008)
J. Neurochem
, vol.105
, pp. 797-806
-
-
Wang, I.F.1
Wu, L.S.2
Chang, H.Y.3
Shen, C.K.4
-
35
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic TAR DNAbinding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton M.J., Igaz L.M., Wong M.M., Kwong L.K., Trojanowski J.Q. and Lee V.M. (2008). Disturbance of nuclear and cytoplasmic TAR DNAbinding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J. Biol. Chem. 283, 13302-13309.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
Lee, V.M.6
-
36
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
Zhang Y.J., Xu Y.F., Dickey C.A., Buratti E., Baralle F., Bailey R., Pickering-Brown S., Dickson D. and Petrucelli L. (2007). Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J. Neurosci. 27, 10530-10534
-
(2007)
J. Neurosci
, vol.27
, pp. 10530-10534
-
-
Zhang, Y.J.1
Xu, Y.F.2
Dickey, C.A.3
Buratti, E.4
Baralle, F.5
Bailey, R.6
Pickering-Brown, S.7
Dickson, D.8
Petrucelli, L.9
|