A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization

Cellular Signalling

Volumn 21, Issue 11, 2009, Pages 1663-1671

  Zhang, Meilin ^a   Feng, Xiuyan ^a   Guan, Rongbin ^a   Hébert, Terence E ^b   Segaloff, Deborah L ^a  

^a UNIVERSITY OF IOWA   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Bioluminescence resonance energy transfer; Dimerization; G protein coupled receptor; Lutropin receptor

Indexed keywords

CHORIONIC GONADOTROPIN; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; HETERODIMER; LUTEINIZING HORMONE RECEPTOR; MELANOCORTIN 3 RECEPTOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CELL MEMBRANE; CELL STIMULATION; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION; WILD TYPE;

AMINO ACID SUBSTITUTION; CELL LINE; CHORIONIC GONADOTROPIN; CYCLIC AMP; DIMERIZATION; HUMANS; MUTATION; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTORS, LH; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 69049102935     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.07.003     Document Type: Article

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