Regulation of cyclooxygenase enzymes by nitric oxide

Cellular and Molecular Life Sciences

Volumn 53, Issue 7, 1997, Pages 576-582

  Salvemini, D ^a  

^a PFIZER INC   (United States)

Author keywords

Cyclooxygenase; Inflammation; Nitric oxide; Prostaglandins

Indexed keywords

ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID; ARGININE; CYTOKINE; GUANYLATE CYCLASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE; PROSTACYCLIN; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; STEROID; THROMBOXANE A2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APOPTOSIS; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; INFLAMMATION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PHYSIOLOGY; PROSTAGLANDIN SYNTHESIS; RAT; REVIEW;

ANIMALS; CARDIOVASCULAR DISEASES; CYCLOOXYGENASE INHIBITORS; ENZYME ACTIVATION; HUMANS; INFLAMMATION; NITRIC OXIDE; PLATELET AGGREGATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; SIGNAL TRANSDUCTION; THROMBOSIS; VASODILATION;

ANIMALIA;

EID: 0030921169     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180050074     Document Type: Review

References (60)

1. Moncada S. and Higgs E. A. (1995) Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J. 9: 1319-1330
2. Clancy R. M. and Abramson S. B. (1995) Nitric oxide: a novel mediator of inflammation. Soc. Expl Biol. Med. 23: 93-101
3. Kroncke K.-D., Fehsel K. and Kolb-Bachofen V. (1995) Inducible nitric oxide synthase and its product nitric oxide, a small molecule with complex biological activities. Biol. Chem. 376: 327-343
4. Needleman P., Turk J., Jakschik B. A., Morrison, A. R. and Lefkowith J. B. (1986) Arachidonic Acid Metabolism. Annu. Rev. Biochem. 55: 69-102
5. Miyamoto T., Ogino N., Yamamoto S. and Hayaishi O. (1976) Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J. Biol. Chem. 251: 2629-2636
6. VanDerOuderaa F., Buyenhek M., Nugteren D. and VanDorp D. (1977) Purification and characterisation of prostaglandin endoperoxide synthase from sheep vesicular glands. Biochim. Biophys. Acta 367: 315
7. DeWitt D. L. and Smith W. L. (1988) Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc. Natl Acad. Sci. USA 85: 1412-1416
8. Merlie J. P., Fagan D., Mudd J. and Needleman P. (1988) Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). J. Biol. Chem. 263: 3550-3553
9. Bailey J. M., Muza B., Hla T. and Salata K. (1985) Restoration of prostacyclin synthase in vascular smooth muscle cells after aspirin treatment: regulation by epidermal growth factor. J. Lipid Res. 26: 54-61
10. DeWitt D. L. (1991) Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim. Biophys. Acta 1083: 121-134
11. Sano H., Hla T., Maier J. A. M., Crofford L. J., Case J. P. Maciag T. et al. (1992) In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis. J. Clin. Invest. 89: 97-10
12. Wu K K. (1995) Inducible cyclooxygenase and nitric oxide synthase. Adv. Pharmacol. 33: 179-207
13. Seibert K., Zhang Y., Leahy K., Hauser S., Masferrer J. L., Perkins W. et al. (1994) Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc. Natl Acad. Sci. USA 91: 12013-12017
14. Masferrer J. L., Zweifel B. S., Manning P. T., Hauser S. D., Leahy K. M., Smith W. G. et al. (1994) Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc. Natl Acad. Sci. USA 91: 3228-3232
15. Masferrer J. L. and Seibert K. (1994) Regulation of prostaglandin synthesis by glucocorticoids. Receptor 94: 25-30
16. Salvemini D., Misko T. P., Masferrer J. L., Seibert K., Currie M. G. and Needleman P. (1993) Nitric oxide activates cyclooxygenase enzymes. Proc. Natl Acad. Sci. USA 90: 7240-7244
17. Salvemini D. and Masferrer J. L. (1996) Interactions of nitric oxide with cyclooxygenase: in vitro, ex vivo and in vivo studies. Meth. Enzymol. 269: 15-26
18. Salvemini D., Misko T. P., Masferrer J., Seibert K., Currie M. G. and Needleman P. (1995) In: Biology of Nitric Oxide Enzymology Biochemistry and Immunology, ch. 4. pp. 304-309, Moncada S., Feelish M. and Busse R. (eds), Role of nitric oxide in the regulation of cyclooxygenase. Portland Press. London
19. Corbett J. A., Tilton R. G., Chang K., Hasan K. S., Ido Y., Wang J. L. et al. (1992) Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes 41: 552-556
20. Misko T. P., Moore W. M., Kasten T. P., Nickols G. A., Corbelt J. A., Tilton R. G. et al. (1993) Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol. 233: 119-125
21. Moore W. M., Webber R. K., Jerome G. M., Tjoeng F. S., Misko T. P. and Currie M. G. (1994) L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J. Med. Chem. 37: 3886-3888
22. Connor J., Manning P. T., Settle S. L., Moore W. M., Jerome G. M., Webber R. K. et al. (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur. J. Pharmacol. 273: 15-24
23. Tsai A. L., Wei C. and Kulmacz R. J. (1994) Interaction between nitric oxide and prostaglandin H synthase. Arch. Biochem. Biophys. 313: 367-372
24. Egan R. W., Paxton J. and Kuehl F. A. Jr. (1976) Mechanism for irreversible self-deactivalion of prostaglandin synthetase. J. Biol. Chem. 251: 7329-7335
25. Gryglweski R. J., Palmer R. M. J. and Moncada S. (1987) Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320: 454-456
26. Hajjar D. P., Lander H. M., Pearce F. S., Upmacis R. K. and Pomerantz K. B. (1995) Nitric oxide enhances prostaglandin-H synthase activity by a heme-independent mechanism: evidence implicating nitrosothiols. J. Am. Chem. Soc. 117: 3340-3346
27. Beckman J. S., Beckman T. W., Chen T. W., Marshall P. A. and Freeman B. A. (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and Superoxide. Proc. Natl Acad. Sci. USA 87: 1620-1624
28. Landino L. M., Crews B. C., Timmons M. D., Morrow J. D. and Marnett L. J. (1996) Peroxynitrite, the coupling product of nitric oxide and Superoxide, activates prostaglandin biosynthesis. Proc. Natl Acad. Sci. USA 93: 15069-15074
29. Bharadwaj L. A. and Prasad K. (1997) Mechanism of hydroxyl radical-induced modulation of vascular tone. Free Radical Biol. Med. 22: 381-390
30. 2 release from the hypothalamus. Proc. Natl Acad. Sci. USA 89: 11543-11546
31. Franchi A. M. Chaud M., Rettori V., Suburu A., McCann S. M. and Gimeno M. (1994) Role of nitric oxide in cicosanoid synthesis and uterine motility in estrogen-treated rat uteri. Proc. Natl Acad. Sci. USA 91: 539-543
32. Anggard E. E. (1991) Endogenous nitrates-implications for treatment and prevention. Eur. Heart. J. 12: 5-8
33. Luscher T. F., Richard V. and Yang Z. (1990) Interaction between endothelium-derived nitric oxide and SIN-1 in human and porcine blood vessels. J. Cardiovasc, Pharmacol, 14: 76-80
34. Parker J. O. (1987) Nitrate therapy in stable angina pectoris. New. Engl. J. Med. 31: 1635-1642
35. Stamler J. S. and Loscalzo J. (1991) The antiplatelet effects of organic nitrates and related nitrous compounds in vitro and in vivo and their relevance to cardiovascular disorders. J. Am. Coll. Cardiol. 18: 1529-1536
36. Davidge S. T., Baker P. N., Mclaughlin M. K. and Roberts J. M. (1995) Nitric oxide produced by endothelial cells increases production of eicosanoids through activation of prostaglandin H synthase. Circ. Res. 77: 274-283
37. Salvemini D., Currie M. G. and Mollace V. (1996) Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators. J. Clin. Invest. 97: 2562-2568
38. Salvemini D., Seibert K., Masferrer J. L., Misko T. P., Currie M. G. and Needleman P. (1994) Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J. Clin. Invest. 93: 1940-1947
39. Salvemini D., Settle S. L., Masferrer J. L., Seibert K., Currie M. G. and Needleman P. (1995) Regulation of prostaglandin production by nitric oxide: an in vivo analysis. Br. J. Pharmacol. 114: 1171-1178
40. Salvemini D., Manning P. T., Zweifel B. S., Seibert K., Connor J., Currie M. G. et al. (1995) Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. J. Clin. Invest. 96: 301-308
41. Salvemini D., Wang Z. Q., Wyatt P. S., Bourdon D. M., Marino M. H., Manning P. T. et al. (1996) Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol. 118: 829-838
42. Vane J. R., Mitchell J. A., Appleton I., Tomlinson A., Bishop-Bailey D., Croxtall J. et al. (1994) Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc. Natl Acad. Sci. USA 91: 2046-2050
43. Sautebin L., Ialenti A., Ianaro A. and Di Rosa M. (1995) Modulation by nitric oxide of prostaglandin biosynthesis in the rat. Br. J. pharmacol. 114: 323-328
44. Sautebin L. and Di Rosa M. (1994) Nitric oxide modulates prostacyclin biosynthesis in the lung of endotoxin-treated rats. Eur. J. Pharmacol. 262: 193-196
45. Closa D., Hotter G., Prats N., Bulbena O., Rosello-Catafau J., Fernandez-Cruz L. et al. (1994) Prostanoid generation in early stages of acute pancreatis: a role for nitric oxide. Inflammation 18: 469-480
46. Marotta P., Santebin L. and Di Rosa M. (1992) Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774 Br. J. Pharmacol. 107: 640-641
47. 2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774. Prostaglandins 49: 105-115
48. Flynn B. L. (1994) Rheumatoid arthritis and osteoarthritis: current and future therapies. Am. Pharm. NS34: 31-42
49. Corbett J. A., Kwon G., Turk J. and McDaniel M. L. (1993) IL1β induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of langerhans: activation of cyclooxygenase by nitric oxide. Biochemistry 32: 13767-13770
50. 2 production by vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 194: 420-424
51. Mollace V., Colasanti V., Rodino P., Lauro G. M., Rotiroti D. and Nistico G. (1995) NMDA-dependent prostaglandin E2 release by human cultured astroglial cells is driven by nitric oxide. Biochem. Biophys. Res. Commun. 215: 793-799
52. Misko T. P., Trotter J. L. and Cross A. H. (1995) Mediation of inflammation by encephalitogenic cells: Interferon γ induction of nitric oxide and cyclooxygenase 2. J. Neuroimmunol. 61: 195-204
53. Swierkosz T. A., Mitchell J. A., Warner T. D., Bolting R. M. and Vane R. (1995) Co-induction of nitric oxide synthase and cyclooxygenase: interactions between nitric oxide and prostanoids. Br. J. Pharmacol. 114: 1335-1342
54. Stadier J., Harbrecht B. C., DiSilvio M., Cumin R. D., Jordan M. L., Simmons R. L. et al. (1993) Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kuppfer cells. J. Leukocyte Biol. 53: 165-172
55. Habib A., Bernard C., Tedgui A. and Maclouf J. (1994) Evidence of cross- talks between inducible nitric oxide synthase and cyclooxygenase II in rat peritoneal macrophages. Abstracts of the 9th International Conference on Prostaglandins and Related Compounds Florence (Italy), June 6 10: 57
56. Raddassi K., Petit J. F. and Lemaire G. (1993) LPS-induced activation of primed murine peritoneal macrophages is modulated by prostaglandins and cyclic nucleotides. Cell. Immunol. 149: 50-64
57. Bulut V., Severn A. and Liew F. Y. (1993) Nitric oxide production by murine macrophages is inhibited by prolonged elevation of cyclic AMP, Biochem. Biophys. Res. Commun. 195: 1134-1138
58. 2 of cytokine-elicited nitric oxide synthesis in rat liver macrophages. Biol. Chem. 373: 897-902
59. Ima T., Hirata Y., Kanno K. and Marumo F. (1994) Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells. J. Clin. Invest. 93: 543-549
60. Hirokawa K., O'Shaughnessy K., Moore K., Ramrakha P. and Wilkins M. R. (1994) Induction of nitric oxide synthase in cultured vascular smooth muscle cells: the role of cyclic AMP. Br. J. Pharmacol. 112: 396-402