Modulation of indomethacin-induced gastric injury by spermine and taurine in rats

Journal of Biochemical and Molecular Toxicology

Volumn 21, Issue 5, 2007, Pages 280-288

  Motawi, Tarek K ^a   Abd Elgawad, Hanan M ^a   Shahin, Nancy N ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Gastric ulcer; Indomethacin; Neutrophil infiltration; NO; Oxidative stress; Spermine; Taurine

Indexed keywords

GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDOMETACIN; MUCIN; MYELOPEROXIDASE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; SPERMINE; SUPEROXIDE DISMUTASE; TAURINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GASTROINTESTINAL TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; SINGLE DRUG DOSE; STOMACH ACID; STOMACH INJURY; STOMACH JUICE; STOMACH MUCOSA; STOMACH PROTECTION; TISSUE REGENERATION;

ANIMALS; GASTRIC MUCOSA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDOMETHACIN; MALE; MUCINS; RATS; RATS, WISTAR; SPERMINE; STOMACH ULCER; SUPEROXIDE DISMUTASE; TAURINE;

ANIMALIA; RATTUS;

EID: 35548934557     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.20194     Document Type: Article

References (54)

1. Griffin MR, Piper JM, Daugherty JR, Snowden M, Ray WA. Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons, Ann Intern Med 1991;114:257-263.
2. Wallace JL. Pathogenesis of NSAID-induced gastroduodenal mucosal injury. Best Pract Res Clin Gastroenterol 2001;15:691-703.
3. Rainsford KD. Microvascular injury during gastric mucosal damage by anti-inflammatory drugs in pigs and rats. Agents Actions 1983;13:457-460.
4. Andrews FJ, Malcontenti-Wilson C, O'Brien PE. Effect of nonsteroidal anti-inflammatory drugs on LFA-1 and ICAM-1 expression in gastric mucosa. Am J Physiol 1994;266:G657-G664.
5. McCarty MF. The reported clinical utility of taurine in ischemic disorders may reflect a down-regulation of neutrophil activation and adhesion. Med Hypotheses 1999;53:290-299.
6. McCall TB, Boughton-Smith NK, Palmer RM, Whittle BJ, Moncada S. Synthesis of nitric oxide from L-arginine by neutrophils. Biochem J 1989;261:293-296.
7. Slomiany BL, Slomiany A. Role of endothelin-converting enzyme-1 in the suppression of constitutive nitric oxide synthase in rat gastric mucosal injury by indomethacin. Scand J Gastroenterol 2000;35:1131-1136.
8. Zhang M, Caragine T, Wang H, Cohen PS, Botchkina G, Soda K, Bianchi M, Ulrich P, Cerami A, Sherry B, Tracey KJ. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: A counterregulatory mechanism that restrains the immune response. J Exp Med 1997;185:1759-1768.
9. Mössner J, Hammermann R, Racke K. Concomitant down-regulation of L-arginine transport and nitric oxide (NO) synthesis in rat alveolar macrophages by the polyamine spermine. Pulm Pharmacol Ther 2001;14:297-305.
10. Al-shabanah OA, Raza M. Effect of ulceration on rat gastric tissue polyamine contents in response to different procedures; inhibition of these effects by cimetidine. Pharmacol Res 1999;40:75-82.
11. Redmond HP, Stapleton PP, Neary P, Bouchier-Hayes D. Immunonutrition: The role of taurine. Nutrition 1998;14:599-604.
12. McLoughlin DM, Stapleton PP, Bloomfield FJ. Influence of taurine and a substituted taurine on the respiratory burst pathway in the inflammatory response. Biochem Soc Trans 1991;19:73-78.
13. Barua M, Liu Y, Quinn MR. Taurine chloramine inhibits inducible nitric oxide synthase and TNF-alpha gene expression in activated alveolar macrophages: Decreased NF-κB activation and I-κB kinase activity. J Immunol 2001;167: 2275-2281.
14. Asad M, Shewade DG, Koumaravelou K, Abraham BK, Balasinor N, Ramaswamy S. Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats. J Pharm Pharmacol 2001;53:1541-1547.
15. Odabasoglu F, Cakir A, Suleyman H, Asian A, Bayir Y, Halici M, Kazaz C. Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in rats. J Ethnopharmacol 2006;103:59-65.
16. Buzás G, Demel Z, Jozan J, Hamar J. Prevention of indomethacin-induced acute gastric mucosal injury by spermine in the rat. Acta Physiol Hung 1996;84:251-258.
17. Son M, Kim HK, Kim WB, Yang J, Kim BK. Protective effects of taurine on indomethacin-induced gastric mucosal injury. Adv Exp Med Bio 1996; 403:147-155.
18. Valcavi U, Caponi R, Brambilla A, Palmira M, Minoja F, Bernini F, Musanti R, Fumagalli R. Gastric antisecretory, antiulcer and cytoprotective properties of 9-hydroxy-19, 20-bis-nor-prostanoic acid in experimental animals. Arzneimittelforschung 1982;32:657-663.
19. Mancuso P, Whelan J, DeMichele SJ, Snider CC, Guszcza JA, Karlstad MD. Dietary fish oil and fish and borage oil suppress intrapulmonary proinflammatory eicosanoid biosynthesis and attenuate pulmonary neutrophil accumulation in endotoxic rats. Crit Care Med 1997; 25:1198-1206.
20. Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984;87:1344-1350.
21. Miranda KM, Espey MG, Wink DA. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 2001;5:62-71.
22. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can. J Biochem Physiol 1959;37:911-917.
23. Recknagel RO, Glende EA Jr. Spectrophotometric detection of lipid conjugated dienes. Methods Enzymol 1984;105:331-337.
24. Ahmed AE, Hussein GI, Loh JP, Abdel-Rahman SZ. Studies on the mechanism of haloacetonitrile-induced gastrointestinal toxicity: Interaction of dibromoacetonitrile with glutathione and glutathione-S-transferase in rats. J Biochem Toxicol 1991;6:115-121.
25. Moghadasian MH, Godin DV. Gender-related regional antioxidant profiles in the gastrointestinal tract of the rat. Mol Cell Biochem 1996;155:43-49.
26. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J Lab Clin Med 1967;70:158-169.
27. Long WK, Carson PE. Increased erythrocyte glutathione reductase in diabetes mellitus. Biochem Biophys Res Commun 1961;5:394-399.
28. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-474.
29. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
30. Shay H, Sun DC, Gruenstein M. A quantitative method for measuring spontaneous gastric secretion in the rat. Gastroenterology 1954;26:906-913.
31. Grossman MI. Gastric secretion. Physiol Physician 1963;1:1-3.
32. Winzler RJ. Determination of serum glycoproteins. Methods Biochem Anal 1955;2:279-311.
33. Davies NM, Wallace JL. Nonsteroidal anti-inflammatory drug-induced gastrointestinal toxicity: New insights into an old problem. J Gastroenterol 1997;32:127-133.
34. Schubert ML. Gastric secretion. Curr Opin Gastroenterol 2005;21:636-643.
35. 3 receptors in urethane-anaesthetized rats. Br J Pharmacol 1996;117:653-656.
36. Şener G, Sehirli O, Cetinel S, Midillioglu S, Gedik N, Ayanoglu-Dulger G. Protective effect of taurine against alendronate-induced gastric damage in rats. Fundam Clin Pharmacol 2005;19:93-100.
37. Brzozowski T, Drozdowicz D, Majka J, Polonczyk-Pytko J, Konturek SJ. Role of polyamines in gastroprotection induced by epidermal growth factor. J Physiol Pharmacol 1991;42:181-193.
38. Nandi J, Wright MV, Fromm D, Ray TK. Oral administration of spermine inhibits gastric acid secretion in rats. Dig Dis Sci 1983;28:513-517.
39. Khattab MM, Gad MZ, Abdallah D. Protective role of nitric oxide in indomethacin-induced gastric ulceration by a mechanism independent of gastric acid secretion. Pharmacol Res 2001;43:463-467.
40. Greco S, Niepceron E, Hugueny I, George P, Louisot P, Biol MC. Dietary spermidine and spermine participate in the maturation of galactosyltransferase activity and glycoprotein galactosylation in rat small intestine. J Nutr 2001;131:1890-1897.
41. Ray JM, Squires PE, Curtis SB, Meloche MR, Buchan AM. Expression of the calcium-sensing receptor on human antral gastrin cells in culture. J Clin Invest 1997;99:2328-2333.
42. Ichikawa T, Ishihara K, Saigenji K, Hotta K. Stimulation of mucus glycoprotein biosynthesis in rat gastric mucosa by gastrin. Biochem Pharmacol 1993;46:1551-1557.
43. Galijasevic S, Saed GM, Diamond MP, Abu-Soud HM. Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition. Proc Natl Acad Sci USA 2003;100:14766-14771.
44. Hammermann R, Dreissig MD, Mössner J, Fuhrmann M, Berrino L, Gothert M, Racke K. Nuclear factor-κB mediates simultaneous induction of inducible nitric-oxide synthase and up-regulation of the cationic amino acid transporter CAT-2B in rat alveolar macrophages. Mol Pharmacol 2000;58:1294-1302.
45. Fennessy FM, Moneley DS, Wang JH, Kelly CJ, Bouchier-Hayes DJ. Taurine and vitamin C modify monocyte and endothelial dysfunction in young smokers. Circulation 2003;107:410-415.
46. Çetiner M, Sener G, Sehirli AO, Eksioglu-Demiralp E, Ercan F, Sirvanci S, Gedik N, Akpulat S, Tecimer T, Yegen BC. Taurine protects against methotrexate-induced toxicity and inhibits leukocyte death. Toxicol Appl Pharmacol 2005;209:39-50.
47. Galati G, Tafazoli S, Sabzevari O, Chan TS, O'Brien PJ. Idiosyncratic NSAID drug induced oxidative stress. Chem Biol Interact 2002;142:25-41.
48. Villegas I, Alarcon de la Lastra C, La Casa C, Motilva V, Martin MJ. Effects of food intake and oxidative stress on intestinal lesions caused by meloxicam and piroxicam in rats. Eur J Pharmacol 2001;414:79-86.
49. Das KC, Misra HP. Hydroxyl radical scavenging and singlet oxygen quenching properties of polyamines. Mol Cell Biochem 2004;262:127-133.
50. Lovaas E, Carlin G. Spermine: An anti-oxidant and anti-inflammatory agent. Free Radic Biol Med 1991;11:455-461.
51. Chu FF, Esworthy RS, Doroshow JH. Role of Se-dependent glutathione peroxidases in gastrointestinal inflammation and cancer. Free Radic Biol Med 2004;36:1481-1495.
52. Kim C, Park E, Quinn MR, Schuller-Levis G. The production of superoxide anion and nitric oxide by cultured murine leukocytes and the accumulation of TNF-α in the conditioned media is inhibited by taurine chloramine. Immunopharmacology 1996;34:89-95.
53. Wu QD, Wang JH, Fenessy F, Redmond HP, Bouchier-Hayes D. Taurine prevents high glucose induced human vascular endothelial cell apoptosis. Am J Physiol 1999;277:C1229-1238.
54. Nandhini AT, Thirunavukkarasu V, Ravichandran, MK, Anuradha CV. Effect of taurine on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats. Singapore Med J 2005;46:82-87.