Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates?

Chemical Biology and Drug Design

Volumn 74, Issue 3, 2009, Pages 317-321

  De Simone, Giuseppina ^a   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a CNR   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Antiepileptic; Brain isoforms; Carbonic anhydrase; Enzyme inhibitor; Zonisamide

Indexed keywords

ANTICONVULSIVE AGENT; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE VII; CARBONATE DEHYDRATASE XII; SULFAMIC ACID; SULFONAMIDE; SULTIAME; TOPIRAMATE; UNCLASSIFIED DRUG; ZONISAMIDE;

ARTICLE; BRAIN; CENTRAL NERVOUS SYSTEM; CORRELATION ANALYSIS; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; MAMMAL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTICONVULSANTS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; HUMANS; MICE; PROTEIN ISOFORMS; RATS; RECOMBINANT PROTEINS; SULFONAMIDES; SULFONIC ACIDS;

MAMMALIA;

EID: 68949199660     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00857.x     Document Type: Article

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