Carbonic anhydrase inhibitors: Aromatic and heterocyclic sulfonamides incorporating adamantyl moieties with strong anticonvulsant activity

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 10, 2004, Pages 2717-2726

  Ilies, Marc A ^a,e   Masereel, Bernard ^b   Rolin, Stéphanie ^b   Scozzafava, Andrea ^c   Câmpeanu, Gheorghe ^a   Cîmpeanu, Valentin ^d   Supuran, Claudiu T ^c  

^a UNIVERSITY OF AGRONOMIC SCIENCES AND VETERINARY MEDICINE OF BUCHAREST   (Romania)

^b UNIVERSITY OF NAMUR   (Belgium)

^c UNIVERSITY OF FLORENCE   (Italy)

^d INSTITUTE OF ORGANIC CHEMISTRY   (Romania)

^e TEXAS A AND M UNIVERSITY AT GALVESTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (ADAMANTAN 1 YLCARBOXAMIDO) 1,3,4 THIDIAZOLE 2 SULFONAMIDE; 5 (ADAMANTAN 1 YLCARBOXIMIDO) 4 METHYL 2DELTA 1,3,4 THIDIAZOLINE 2 SULFONAMIDE; ACETIC ACID; ADAMANTANE DERIVATIVE; AMANTADINE DERIVATIVE; ANTICONVULSIVE AGENT; AROMATIC COMPOUND; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBOXYL GROUP; CARBOXYLIC ACID DERIVATIVE; HETEROCYCLIC COMPOUND; SULFONAMIDE; UNCLASSIFIED DRUG;

ACYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CONVULSION; DERIVATIZATION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ELECTRICITY; LIPOPHILICITY; MATHEMATICAL COMPUTING; MOUSE; NEUROPROTECTION; NONHUMAN; REACTION ANALYSIS;

ANIMALS; ANTICONVULSANTS; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; ELECTROSHOCK; MALE; MEMBRANES, ARTIFICIAL; MICE; MICE, INBRED STRAINS; SULFONAMIDES;

EID: 2142808112     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.008     Document Type: Article

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