Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems

Analytical Chemistry

Volumn 81, Issue 16, 2009, Pages 6581-6589

  Robinette, Steven L ^a   Veselkov, Kirill A ^a   Bohus, Eszter ^a,b   Coen, Muireann ^a   Keun, Hector C ^a   Ebbels, Timothy M D ^a   Beckonert, Olaf ^a   Holmes, Elaine C ^a   Lindon, John C ^a   Nicholson, Jeremy K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL INFORMATION; BIOFLUID MIXTURES; BIOFLUIDS; BIOLOGICAL INFORMATION; CO-EXPRESSION; FUNCTIONAL GENOMICS; GALACTOSAMINE; GLOBAL CORRELATION; GRAPHICAL FORMAT; H NMR SPECTRA; HIGH-THROUGHPUT; INFORMATION RECOVERY; INTERPRETABILITY; L-ARGININE; METABOLIC DATA; MICROBIAL FERMENTATION; NEW APPROACHES; PATHOLOGICAL PROCESS; QUANTITATIVE CHANGES; SPECTRAL DATA; SPECTRAL PEAK; TEMPORAL DYNAMICS; UNSUPERVISED APPROACHES; URINE SAMPLE;

AMINO ACIDS; BIOCHEMISTRY; BIOLOGICAL SYSTEMS; BIOMOLECULES; CLUSTER ANALYSIS; COORDINATION REACTIONS; METABOLITES; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RESONANCE;

METABOLISM;

2 BROMOETHYLAMINE; ARGININE; GALACTOSAMINE; PARACETAMOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CLUSTER ANALYSIS; CONTROLLED STUDY; METABOLITE; NONHUMAN; PANCREATITIS; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; URINALYSIS;

CLUSTER ANALYSIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SPECTRUM ANALYSIS;

EID: 68849110493     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac901240j     Document Type: Article

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