Modulation of Ionizing Radiation-Induced G2 Arrest by Cyclooxygenase-2 and its Inhibitor Celecoxib

International Journal of Radiation Oncology Biology Physics

Volumn 75, Issue 1, 2009, Pages 225-234

  Jun, Hyun Jung ^a   Kim, Young Mee ^a   Park, Soo Yeon ^a   Park, Ji Sun ^a,b   Lee, Eun Jung ^a   Choi, Shin Ae ^a   Pyo, Hongryull ^a  

^a National Cancer Center   (South Korea)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

ATR; celecoxib; COX 2; G2 arrest; radiation

Indexed keywords

AFTER-TREATMENT; ATAXIA TELANGIECTASIA; ATR; CANCER CELLS; CELECOXIB; CELL LINES; COX-2; CYCLOOXYGENASE 2; DOWN-REGULATION; FLUORESCENCE-ACTIVATED CELL SORTERS; G2 ARREST; MOLECULAR MECHANISM; OVER-EXPRESSION; PRE-TREATMENT; REVERSE TRANSCRIPTASE- POLYMERASE CHAIN REACTION; SELECTIVE INHIBITORS; WESTERN BLOTS;

CELL CULTURE; CONFOCAL MICROSCOPY; IONIZING RADIATION; RADIATION SHIELDING; RADIOACTIVITY;

CELL MEMBRANES;

ATM PROTEIN; CELECOXIB; CHECKPOINT KINASE RAD3; CYCLOOXYGENASE 2;

ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

CELL CYCLE PROTEINS; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DNA REPAIR; DOWN-REGULATION; FLOW CYTOMETRY; G2 PHASE; HCT116 CELLS; HUMANS; MITOSIS; PROTEIN-SERINE-THREONINE KINASES; PYRAZOLES; RADIATION TOLERANCE; RNA, MESSENGER; SULFONAMIDES; TIME FACTORS; UP-REGULATION;

EID: 68649117124     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.04.086     Document Type: Article

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