In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: Mechanistic considerations

International journal of radiation oncology, biology, physics

Volumn 54, Issue 3, 2002, Pages 886-894

  Raju, Uma ^a   Nakata, Eiko ^a   Yang, Peiying ^a   Newman, Robert A ^a   Ang, Kian K ^a   Milas, Luka ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Cyclins; Cyclooxygenase 2; G2 M phase; Radiation damage; SC 236

Indexed keywords

4 (5 (4 CHLOROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL)BENZENESULFONAMIDE; 4-(5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)BENZENESULFONAMIDE; CCNA1 PROTEIN, MOUSE; COLORING AGENT; CYCLIN A; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DIAGNOSTIC AGENT; ISOENZYME; MESSENGER RNA; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRAZOLE DERIVATIVE; RADIOSENSITIZING AGENT; SULFONAMIDE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; CELL SURVIVAL; DNA DAMAGE; DRUG EFFECT; DRUG SCREENING; METABOLISM; MOUSE; NICK END LABELING; RADIATION DOSE; RADIATION EXPOSURE;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL SURVIVAL; COLORING AGENTS; CYCLIN A; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DNA DAMAGE; DRUG SCREENING ASSAYS, ANTITUMOR; IN SITU NICK-END LABELING; ISOENZYMES; MICE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; RADIATION DOSAGE; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; RNA, MESSENGER; SULFONAMIDES; TETRAZOLIUM SALTS; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0036834430     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(02)03023-7     Document Type: Article

References (52)

1. M Tsujii R.N DuBois Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 Cell 83 1995 493 501
2. M Oshima J.E Dinchuk S.L Kargman Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase (COX-2) Cell 87 1996 803 809
3. M Tsulii S Kawano S Tsuji Cyclooxygenase regulates angiogenesis induced by colon cancer cells Cell 93 1998 705 716
4. H Murata S Kawano S Tsuji Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma Am J Gastroenterol 94 1999 451 455
5. K Kozaki K Koshikawa Y Tatematsu Multifaceted analysis of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis Oncogene 20 2001 4228 4234
6. G Chan J.O Boyle E.K Yang Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck Cancer Res 59 1999 991 994
7. T Hida Y Yatabe H Achiwa Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas Cancer Res 58 1998 3761 3764
8. A Ristimaki N Honkanen H Jankala Expression of cyclooxygenase 2 in human gastric carcinoma Cancer Res 57 1997 1276 1280
9. C.E Eberhart R.J Coffey A Radhika Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas Gastroenterology 107 1994 1183 1188
10. O.N Tucker A.J Dannenberg E.K Yang Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer Cancer Res 59 1999 987 990
11. S Gupta M Srivastava N Ahmad Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma Prostate 42 2000 73 78
12. M.L Parrett R.E Harris F.S Joarder Cyclooxygenase gene expression in human breast cancer Int J Oncol 10 1997 503 507
13. K.C Zimmerman M Sarbia A Weber Cyclooxygenase-2 expression in human esophageal carcinoma Cancer Res 59 1999 198 204
14. A Koki K.M Leahy J.L Masferrer Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy Expert Opinion on Investigational Drugs 8 1999 1623 1638
15. M Ziche S Jones P.M Gullino Role of prostaglandin E and copper in angiogenesis J Natl Cancer Inst 69 1982 475 481
16. S Gately The contributions of cyclooxygenase-2 to tumor angiogenesis Cancer Metastasis Rev 19 2000 19 27
17. T Kawamori C.V Rao K Seibert Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis Cancer Res 58 1998 409 412
18. A.J Dannenberg D Zakim Chemoprevention of colorectal cancer through inhibition of cyclooxygenase-2 Semin Oncol 26 1999 499 504
19. M.M Taketo Cyclooxygenase-2 inhibitors in tumorigenesis (part II) J Natl Cancer Inst 90 1998 1609 1620
20. G Steinbach P.M Lynch R.K.S Phillips The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis N Engl J Med 342 2000 1946 1952
21. L Milas K Kishi N Hunter Enhancement of tumor response to γ-radiation by an inhibitor of cyclooxygenase-2 enzyme J Natl Cancer Inst 91 1999 1501 1504
22. W Dempke C Rie A Grothey Cyclooxygenase-2 A novel target for cancer chemotherapy? J Cancer Res Clin Oncol 127 2001 411 417
23. C Petersen S Petersen L Milas Enhancement of intrinsic tumor cell radiosensitivity induced by a selective cyclooxygenase-2 inhibitor Clin Cancer Res 6 2000 2513 2520
24. T Hida K Kozaki H Muramatsu Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines Clin Cancer Res 6 2000 2006 2011
25. T Kamijo T Sat Y Nagatomi Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines Int J Urol 8 2001 S35 S39
26. M Li X Wu X Xu Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome c-dependent pathway in esophageal cancer cells Int J Cancer 93 2001 218 223
27. K Kishi S Petersen C Petersen Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor Cancer Res 60 2000 1326 1331
28. J.L Masferrer K.M Leahy A.T Koki Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors Cancer Res 60 2000 1306 1311
29. L Milas Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse Semin Radiat Oncol 11 2001 290 299
30. Y Furuta N Hunter T Barkley Increase in radioresponse of murine tumors by treatment with indomethacin Cancer Res 48 1988 3008 3013
31. L Milas Y Furuta N Hunter Dependence on indomethacin-induced potentiation of murine tumor radioresponse on tumor host immunocompetence Cancer Res 50 1990 4473 4477
32. L Milas W.R Hanson Eicosanoids and radiation Eur J Cancer 31A 1995 1580 1585
33. B.A Teicher S.A Holden G Ara Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma Cancer Chemother Pharmacol 38 1996 169 177
34. H Pyo H Choy G.P Amorino A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2 Clin Cancer Res 7 2001 2998 3005
35. A.F Soriano B Helfrich D.C Chan Synergistic effects of new chemopreventive agents and conventional cytotoxic agents against human lung cancer cell lines Cancer Res 59 1999 6178 6184
36. B.A Teicher S.A Holden N.P Dupuis Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma Breast Cancer Treat 36 1995 227 236
37. D.H Gorski H.J Mauceri R.M Salloum Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin Cancer Res 58 1998 5686 5689
38. L Li A Roioni D.W Siemann Targeting the tumor vasculature with combretastatin A-4 disodium phosphate Effects on radiation therapy Int J Radiat Oncol Biol Phys 42 1998 899 903
39. D.H Gorski M.A Beckett N.T Jaskowiak Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation Cancer Res 59 1999 3374 3378
40. B Fertil E.P Malaise Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy Int J Radiat Biol 7 1981 621 629
41. E.C Kempen P Yang E Felix Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high performance liquid chromatography/electrospray ionization tandem mass spectrometry Anal Biochem 297 2001 183 190
42. C.J Torrance P.E Jackson E Montgomery Combinatorial chemoprevention of intestinal neoplasia [see comments] Nat Med 6 2000 1024 1028
43. A.P Dicker T.L Williams D.S Grant Targeting angiogenic processes by combination rofecoxib and ionizing radiation Am J Clin Oncol 24 2001 438 442
44. R.E Meyn L.C Stephens K.K Ang Heterogeneity in the development of apoptosis in irradiated murine tumors of different histologies Int J Radiat Biol 63 1993 583 591
45. T.S Lawrence M.A Davis A Hough A role of apoptosis in 2′,2′-difluoro-2′-deoxycytidine (gemcitabine)-mediated radiosensitization Clin Cancer Res 7 2001 314 319
46. W.K Sinclair R.A Mortan X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells Radiat Res 29 1966 450 474
47. H.C Chang C.F Weng Cyclooxygenase-2 level and culture conditions influence NS398-induced apoptosis and caspase activation in lung cancer cells Oncol Reports 8 2001 1321 1325
48. K Krause M Wasner W Reinhard The tumour suppressor protein p53 can repress transcription of cyclin B Nucleic Acids Res 28 2000 4410 4418
49. F.F Lang W.K Yung R Sawaya Adenovirus-mediated p53 gene therapy for human gliomas [Review] Neurosurgery 45 1999 1093 1104
50. R Schimming K.A Mason N Hunter Lack of correlation between mitotic arrest and antitumor effect of docetaxol Cancer Chemother Pharmacol 43 1999 165 172
51. P van Buul A van Duyn-Goedhart K Sankaranarayanan In vivo and in vitro radioprotective effects of the prostaglandin E1 analogue misoprostol in DNA repair-proficient and -deficient rodent cell systems Radiat Res 152 1999 398 403
52. S.T Palayoor E.A Bump S.K Calderwood Combined antitumor effect of radiation and ibuprofen in human prostate carcinoma cells Clin Cancer Res 4 1998 763 771