Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6

Drug and Alcohol Dependence

Volumn 104, Issue 3, 2009, Pages 187-196

  Raehal, Kirsten M ^a   Schmid, Cullen L ^a,b   Medvedev, Ivan O ^c   Gainetdinov, Raul R ^d   Premont, Richard T ^e   Bohn, Laura M ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c ST ELIZABETH'S MEDICAL CENTER   (United States)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Constipation; G protein coupled receptor kinase; Locomotor activity; Morphine; Mu opioid receptor; Sensitization

Indexed keywords

BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR KINASE 6; MORPHINE SULFATE; MU OPIATE RECEPTOR;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BEHAVIORAL RESEARCH; CONSTIPATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG TOLERANCE; ENZYME ACTIVITY; GENE REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOCOMOTION; MORPHINE ADDICTION; MOUSE; NEUROPATHOLOGY; NEUROPHYSIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLACE PREFERENCE; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANALGESICS, OPIOID; ANIMALS; CELLS, CULTURED; CONDITIONING (PSYCHOLOGY); DRUG TOLERANCE; G-PROTEIN-COUPLED RECEPTOR KINASES; GASTROINTESTINAL TRACT; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; MOTOR ACTIVITY; PAIN MEASUREMENT; RECEPTORS, OPIOID, MU; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS;

ANIMALIA; MUS;

EID: 68349137968     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2009.04.011     Document Type: Article

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