Acute and chronic morphine treatments and morphine withdrawal differentially regulate GRK2 and GRK5 gene expression in rat brain

Neuropharmacology

Volumn 43, Issue 5, 2002, Pages 809-816

  Fan, X ^a   Zhang, J ^a   Zhang, X ^a   Yue, W ^a   Ma, L ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

G protein coupled receptor kinase; Gene expression; Morphine; Opioid tolerance and dependence

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 5; MESSENGER RNA; MORPHINE; NALOXONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG WITHDRAWAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LOCUS CERULEUS; MALE; NEGATIVE FEEDBACK; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THALAMUS; THALAMUS LATERAL NUCLEUS;

ANALGESICS, OPIOID; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; BRAIN CHEMISTRY; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIGOXIGENIN; IN SITU HYBRIDIZATION; MALE; MORPHINE; OLIGONUCLEOTIDE PROBES; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0036801618     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00147-8     Document Type: Article

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