Increased rewarding properties of morphine in dopamine-transporter knockout mice

European Journal of Neuroscience

Volumn 12, Issue 5, 2000, Pages 1827-1837

  Spielewoy, Cécile ^a   Gonon, François ^b   Roubert, Christine ^a   Fauchey, Valérie ^b   Jaber, Mohamed ^b   Caron, Marc G ^c   Roques, Bernard P ^a   Hamon, Michel ^a   Betancur, Catalina ^a   Maldonado, Rafael ^a,d   Giros, Bruno ^a  

^a INSERM   (France)

^b CNRS   (France)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

c fos expression; Conditioned place preference; In vivo voltammetry; Locomotion; Morphine withdrawal

Indexed keywords

DOPAMINE; DOPAMINE TRANSPORTER; MORPHINE; NALOXONE; OPIATE RECEPTOR;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG WITHDRAWAL; ELECTROSTIMULATION; GENE DISRUPTION; GENETIC TRANSCRIPTION; LIMBIC SYSTEM; LOCOMOTION; MOUSE; MUTANT; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; ONCOGENE C FOS; PLACE PREFERENCE; PRIORITY JOURNAL;

ANALGESIA; ANIMALS; CARRIER PROTEINS; CHOICE BEHAVIOR; CONDITIONING, OPERANT; CROSSES, GENETIC; CUES; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; LIGHT; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; MORPHINE DEPENDENCE; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; PHOTIC STIMULATION; REWARD;

EID: 0034021485     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00063.x     Document Type: Article

References (55)

1. Barrot, M., Marinelli, M., Abrous, D.N., Rougé-Pont, F., Le Moal, M. & Piazza, P.V. (1999) Functional heterogeneity in dopamine release and in the expression of fos-like proteins within the rat striatal complex. Eur. J. Neurosci., 11, 1155-1166.
2. Bontempi, B. & Sharp, F.R. (1997) Systemic morphine-induced fos protein in the rat striatum and nucleus accumbens is regulated by μ opioid receptors in the substantia nigra and ventral tegmental area. J. Neurosci., 17, 8596-8612.
3. Carr, G.D., Fibiger, H.C. & Phillips, A.G. (1989) Conditioned place preference as a measure of drug reward. In Leibman, J.M., Cooper, S.J. (eds), The Neuropharmacological Basis of Reward, Oxford University Press, Oxford, pp. 264-319.
4. Corbett, A.D., Paterson, S.J. & Kosterlitz, H.W. (1993) Selectivity of ligands for opioid receptors. In Herz, A. (ed.), Opioids I, Handbook of Experimental Pharmacology. Springer Verlag, Heidelberg, pp. 645-679.
5. Di Chiara, G. (1995) The role of dopamine in drug abuse viewed from the perspective of its role in motivation. Drug Alcohol. Depend., 38, 95-137.
6. Di Chiara, G. & Imperato, A. (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl Acad. Sci. USA, 85, 5274-5278.
7. Di Chiara, G. & North, R.A. (1992) Neurobiology of opiate abuse. Trends Pharmacol. Sci., 13, 185-193.
8. Dugast, C., Suaud-Chagny, M.F. & Gonon, F. (1994) Continuous in vivo monitoring of evoked dopamine release in the rat nucleus accumbens by amperometry. Neuroscience, 62, 647-654.
9. Ettenberg, A., Pettit, H.O., Bloom, F.E. & Koob, G.F. (1982) Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems. Psychopharmacology. 78, 204-209.
10. Giros, B. & Caron, M.G. (1993) Molecular characterization of the dopamine transporter. Trends Pharmacol. Sci., 14, 43-49.
11. Giros, B., Jaber, M., Jones, S.R., Wightman, R.M. & Caron, M.G. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature, 379, 606-612.
12. Gonon, F.G. & Buda, M.J. (1985) Regulation of dopamine release by impulse flow and by autoreceptors as studied by in vivo voltammetry in the rat striatum. Neuroscience, 14, 765-774.
13. Harris, G.C. & Aston-Jones, G. (1994) Involvement of D2 dopamine receptors in the nucleus accumbens in the opiate withdrawal syndrome. Nature, 371, 155-157.
14. Horn, A.S. (1990) Dopamine uptake: a review of progress in the last decade. Progr. Neurobiol., 34, 387-400.
15. Johnson, S.W. & North, R.A. (1992) Opioids excite dopamine neurons by hyperpolarization of local interneurons. J. Neurosci., 12, 483-488.
16. Jones, S.R., Gainetdinov, R.R., Jaber, M., Giros, B., Wightman, R.M. & Caron, M.G. (1998) Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proc. Natl Acad. Sci. USA, 95, 4029-4034.
17. Jones, S.R., Gainetdinov, R.R., Hu, X.-T., Cooper, D.C., Wightman, R.M., White, F.J. & Caron, M.C. (1999) Loss of autoreceptor functions in the mice lacking the dopamine transporter. Nat. Neurosci., 2, 649-655.
18. Jordan, D., Tafani, J.A., Ries, C., Zajac, J.M., Simmonet, J., Martin, D., Kopp, N. & Allard, M. (1996) Evidence for mutiple opiod receptors in the humans posterior pituitary. J. Neuroendocrinol., 8, 883-887.
19. Kalivas, P.W., Widerlov, E., Stanley, D., Breese, G. & Prange, A.J. (1983) Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity. J. Pharmacol. Exp. Ther., 227, 229-237.
20. Klitenick, M.A., DeWitte, P. & Kalivas, P.W. (1992) Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. J. Neurosci., 12, 2623-2632.
21. Koob, G.F. (1992) Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol. Sci., 13, 177-184.
22. Koob, G.F. & Bloom, F.E. (1988) Cellular and molecular mechanisms of drug dependence. Science, 242, 715-723.
23. Koob, G.F. & Le Moal, M. (1997) Drug abuse: hedonic homeostatic dysregulation. Science, 278, 52-58.
24. Kuhar, M.J., Ritz, M.C. & Boja, J.W. (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci., 14, 299-302.
25. Le Moine, C., Svenningsson, P., Fredholm, B.B. & Bloch, B. (1997) Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2a receptors enhences D1 receptor-mediated effects on c-fos expression. J. Neurosci., 17, 8038-8048.
26. Liu, J., Nickolenko, J. & Sharp, F.R. (1994) Morphine induced c-fos and junB in striatum and nucleus accumbens via D1 and N-methyl-D-aspartate receptors. Proc. Natl Acad. Sci. USA, 91, 8537-8541.
27. Mackey, W.B. & Van Der Kooy, D. (1985) Neuroleptics block the positive reinforcing effects of amphetamine but not of morphine as measured by place conditioning. Pharm. Biochem. Behav., 22, 101-105.
28. Maldonado, R., Saiardi, A., Valverde, O., Samad, T.A., Roques, B.P. & Borrelli, E. (1997) Absence of opiate rewarding effects in mice lacking dopamine D2 receptors. Nature, 388, 586-589.
29. Maldonado, R., Stinus, L. & Koob, G.F. (1996) Neurobiological mechanisms of opiate withdrawal. Medical Intelligence Unit. Springer-Verlag, Heidelberg.
30. Matthes, H.W., Maldonado, R., Simonin, F., Valverde, O., Slowe, S., Kitchen, I., Befort, K., Dierich, A., Le Meur, M., Dolle, P., Tzavara, E., Hanoune, J., Roques, B.P. & Kieffer, B.L. (1996) Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature, 383, 819-823.
31. Matthews, R.T. & German, D.C. (1984) Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine. Neuroscience, 11, 617-625.
32. Michael-Titus, A., Dourmap, N. & Costentin, J. (1989) Mu and delta opioid receptors control differently the horizontal and vertical components of locomotor activity in mice. Neuropeptides, 13, 235-242.
33. Mickley, G.A., Mulvihill, M.A. & Postler, M.A. (1990) Brain μ and δ opioid receptors mediate different locomotor hyperactivity responses of the C57BL/6J mouse. Psychopharmacology, 101, 332-337.
34. Mucha, R.F. & Iversen, S.D. (1984) Reinforcing properties of morphine and naloxone revealed by conditioned place preferences: a procedural examination. Psychopharmacology, 82, 241-247.
35. Mucha, R.F., van der Kooy, D., O'Shaughnessy, M. & Bucenieks, P. (1982) Drug reinforcement studied by the use of place conditioning in rat. Brain Res., 243, 91-105.
36. Nestler, E.J. & Aghajanian, G.K. (1997) Molecular and cellular basis of addiction. Science, 278, 58-63.
37. Nestler, E.J., Berthow, M.T. & Brodkin, E.S. (1996) Molecular mechanisms of drug addiction: adaptations in signal transduction pathways. Mol. Psychiatry, 1, 190-199.
38. Nestler, E.J., Hope, B.T. & Widnell, K.L. (1993) Drug addiction: a model for the molecular basis of neural plasticity. Neuron, 11, 995-1006.
39. Paxinos, G. & Franklin, K.B.J. (1996) The Mouse Brain in Stereotaxic Coordinates. Academic Press, San Diego, USA.
40. Pettit, H.O., Ettenberg, A., Bloom, F.E. & Koob, G.F. (1984) Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology, 84, 167-173.
41. Piepponen, T.P., Honkanen, A., Kivastik, T., Zharkovsky, A., Turtia, A., Mikkola, J.A.V. & Ahtee, L. (1999) Involvement of opioid μ1-receptors in opioid-induced acceleration of striatal and limbic dopaminergic transmission. Pharm. Biochem. Behav., 63, 245-252.
42. Piepponen, T.P., Kivastik, T., Katajamäki, J., Zharkovsky, A. & Ahtee, L. (1997) Involvement of opioid μ1 receptors in morphine-induced conditioned place preference in rats. Pharm. Biochem. Behav., 58, 275-279.
43. Pontieri, F.E., Tanda, G. & Di Chiara, G. (1995) Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the 'shell' as compared with the 'core' of the rat nucleus accumbens. Proc. Natl Acad. Sci. USA, 92, 12304-12308.
44. Rocha, B.A., Fumagalli, F., Gainetdinov, R.R., Jones, S.R., Ator, R., Giros, B., Miller, G.W. & Caron, M.G. (1998) Cocaine self-administration in dopamine-transporter knockout mice. Nat. Neurosci., 1, 132-137.
45. Self, D.W. (1998) Neural substrate of drug craving and relapse in drug addiction. Ann. Med., 30, 379-389.
46. Shippenberg, T.S. & Elmer, G.I. (1998) The neurobiology of opiate reinforcement. Crit. Rev. Neurobiol., 12, 267-303.
47. Shippenberg, T.S., Emmett-Oglesby, M.W., Ayesta, F.J. & Herz, A. (1988) Tolerance and selective cross-tolerance to the motivational effects of opioids. Psychopharmacology, 96, 110-115.
48. Sora, I., Wickems, C., Takahashi, N., Li, X.-F., Zeng, Z., Revay, R., Lesch, K.P., Murphy, D.L. & Uhl, G.R. (1998) Cocaine reward models: conditioned place preference can be established in dopamine-and in serotonin-transporter knockout mice. Proc. Natl Acad. Sci. USA, 9, 7699-7704.
49. Stinus, L., Cador, M. & Le Moal, M. (1992) Interaction between endogenous opioids and dopamine within the nucleus accumbens. Ann. N. Y. Acad. Sci., 654, 254-273.
50. Stinus, L., Winnock, M. & Kelley, A.E. (1985) Chronic neuroleptic treatment and mesolimbic dopamine denervation induce behavioural supersensitivity to opiates. Psychopharmacology, 85, 323-328.
51. Suaud-Chagny, M.F., Chergui, K., Chouvet, G. & Gonon, F. (1992) Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area. Neuroscience, 49, 63-72.
52. Valverde, O., Fournié-Zaluski, M.-C, Roques, B.P. & Maldonado, R. (1995) The CCKB antagonist PD-134,308 facilitates rewarding effects of endogenous enkephalins but does not induce place preference in rats. Psychopharmacology, 123, 119-126.
53. Vezina, P. & Stewart, J. (1987) Conditioned locomotion and place preference elicited by tactile cues paired exclusively with morphine in an open field. Psychopharmacology, 91, 375-380.
54. Wise, R.A. & Bozarth, M.A. (1987) A psychomotor stimulant theory of addiction. Psychol. Rev., 94, 469-492.
55. Wise, R.A. & Rompre, P.-P. (1989) Brain dopamine and reward. Annu. Rev. Psychol., 40, 191-225.