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Volumn , Issue 24, 2009, Pages 4085-4090

Enantioselective halogenation of β-oxo esters catalyzed by a chiral sulfoximine-copper complex

Author keywords

Asymmetric catalysis; Copper; Enantioselectivity; Halogenation; Sulfoximines

Indexed keywords


EID: 68349119284     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.200900467     Document Type: Article
Times cited : (57)

References (100)
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    • Both enantiomers of 4a are commercially available from Sigma-Aldrich (CAS numbers 825612-43-9 and 948831-14-9).
    • Both enantiomers of 4a are commercially available from Sigma-Aldrich (CAS numbers 825612-43-9 and 948831-14-9).
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    • The absolute configurations of the chlorinated oxo esters 9b,df and the brominated products 15b and 15f were determined to be (JR) by comparison of the values of the optical, rotations with those reported in the literature. The absolute configurations of the fluorinated products 16d and 16e were determined to be (S) by comparison with literature data. The absolute configurations of other halogenated products were assigned by analogy.
    • The absolute configurations of the chlorinated oxo esters 9b,df and the brominated products 15b and 15f were determined to be (JR) by comparison of the values of the optical, rotations with those reported in the literature. The absolute configurations of the fluorinated products 16d and 16e were determined to be (S) by comparison with literature data. The absolute configurations of other halogenated products were assigned by analogy.


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