-
1
-
-
28144441826
-
The bacterial ribosome as a target for antibiotics
-
Poehlsgaard J., and Douthwaite S. The bacterial ribosome as a target for antibiotics. Nat. Rev., Microbiol. 3 (2005) 870-881
-
(2005)
Nat. Rev., Microbiol.
, vol.3
, pp. 870-881
-
-
Poehlsgaard, J.1
Douthwaite, S.2
-
2
-
-
33645465733
-
Antibiotics and the ribosome
-
Tenson T., and Mankin A.S. Antibiotics and the ribosome. Mol. Microbiol. 59 (2006) 1664-1677
-
(2006)
Mol. Microbiol.
, vol.59
, pp. 1664-1677
-
-
Tenson, T.1
Mankin, A.S.2
-
3
-
-
20444495201
-
Drugs targeting the ribosome
-
Hermann T. Drugs targeting the ribosome. Curr. Opin. Struct. Biol. 15 (2005) 355-366
-
(2005)
Curr. Opin. Struct. Biol.
, vol.15
, pp. 355-366
-
-
Hermann, T.1
-
4
-
-
0034727834
-
Managing antibiotic resistance
-
Wenzel R.P., and Edmond M.B. Managing antibiotic resistance. N. Engl. J. Med. 343 (2000) 1961-1963
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1961-1963
-
-
Wenzel, R.P.1
Edmond, M.B.2
-
5
-
-
0035957387
-
A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit
-
Belova L., Tenson T., Xiong L., McNicholas P.M., and Mankin A.S. A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit. Proc. Natl Acad. Sci. USA 98 (2001) 3726-3731
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 3726-3731
-
-
Belova, L.1
Tenson, T.2
Xiong, L.3
McNicholas, P.M.4
Mankin, A.S.5
-
6
-
-
10344235275
-
Combinatorial genetic technology for the development of new anti-infectives
-
Laios E., Waddington M., Saraiya A.A., Baker K.A., O'Connor E., Pamarathy D., and Cunningham P.R. Combinatorial genetic technology for the development of new anti-infectives. Arch. Pathol. Lab. Med. 128 (2004) 1351-1359
-
(2004)
Arch. Pathol. Lab. Med.
, vol.128
, pp. 1351-1359
-
-
Laios, E.1
Waddington, M.2
Saraiya, A.A.3
Baker, K.A.4
O'Connor, E.5
Pamarathy, D.6
Cunningham, P.R.7
-
7
-
-
28044462415
-
Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics
-
Yassin A., Fredrick K., and Mankin A.S. Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics. Proc. Natl Acad. Sci. USA 102 (2005) 16620-16625
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 16620-16625
-
-
Yassin, A.1
Fredrick, K.2
Mankin, A.S.3
-
8
-
-
34548236988
-
Potential new antibiotic sites in the ribosome revealed by deleterious mutations in RNA of the large ribosomal subunit
-
Yassin A., and Mankin A.S. Potential new antibiotic sites in the ribosome revealed by deleterious mutations in RNA of the large ribosomal subunit. J. Biol. Chem. 282 (2007) 24329-24342
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24329-24342
-
-
Yassin, A.1
Mankin, A.S.2
-
9
-
-
10744232512
-
Novel antibacterial class
-
Dandliker P.J., Pratt S.D., Nilius A.M., Black-Schaefer C., Ruan X., Towne D.L., et al. Novel antibacterial class. Antimicrob. Agents Chemother. 47 (2003) 3831-3839
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 3831-3839
-
-
Dandliker, P.J.1
Pratt, S.D.2
Nilius, A.M.3
Black-Schaefer, C.4
Ruan, X.5
Towne, D.L.6
-
10
-
-
33745608210
-
Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits
-
Brandi L., Fabbretti A., Di Stefano M., Lazzarini A., Abbondi M., and Gualerzi C.O. Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits. RNA 12 (2006) 1262-1270
-
(2006)
RNA
, vol.12
, pp. 1262-1270
-
-
Brandi, L.1
Fabbretti, A.2
Di Stefano, M.3
Lazzarini, A.4
Abbondi, M.5
Gualerzi, C.O.6
-
11
-
-
30444456799
-
Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic
-
Brandi L., Fabbretti A., La Teana A., Abbondi M., Losi D., Donadio S., and Gualerzi C.O. Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic. Proc. Natl Acad. Sci. USA 103 (2006) 39-44
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 39-44
-
-
Brandi, L.1
Fabbretti, A.2
La Teana, A.3
Abbondi, M.4
Losi, D.5
Donadio, S.6
Gualerzi, C.O.7
-
12
-
-
33645227437
-
Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp
-
Brandi L., Lazzarini A., Cavaletti L., Abbondi M., Corti E., Ciciliato I., et al. Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp. Biochemistry 45 (2006) 3692-3702
-
(2006)
Biochemistry
, vol.45
, pp. 3692-3702
-
-
Brandi, L.1
Lazzarini, A.2
Cavaletti, L.3
Abbondi, M.4
Corti, E.5
Ciciliato, I.6
-
13
-
-
0031933080
-
RNA as a drug target: chemical, modelling, and evolutionary tools
-
Hermann T., and Westhof E. RNA as a drug target: chemical, modelling, and evolutionary tools. Curr. Opin. Biotechnol. 9 (1998) 66-73
-
(1998)
Curr. Opin. Biotechnol.
, vol.9
, pp. 66-73
-
-
Hermann, T.1
Westhof, E.2
-
14
-
-
0038309315
-
Structure-based design of agents targeting the bacterial ribosome
-
Bower J., Drysdale M., Hebdon R., Jordan A., Lentzen G., Matassova N., et al. Structure-based design of agents targeting the bacterial ribosome. Bioorg. Med. Chem. Lett. 13 (2003) 2455-2458
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 2455-2458
-
-
Bower, J.1
Drysdale, M.2
Hebdon, R.3
Jordan, A.4
Lentzen, G.5
Matassova, N.6
-
15
-
-
27644491082
-
Structures of the bacterial ribosome at 3.5 Å resolution
-
Schuwirth B.S., Borovinskaya M.A., Hau C.W., Zhang W., Vila-Sanjurjo A., Holton J.M., and Cate J.H. Structures of the bacterial ribosome at 3.5 Å resolution. Science 310 (2005) 827-834
-
(2005)
Science
, vol.310
, pp. 827-834
-
-
Schuwirth, B.S.1
Borovinskaya, M.A.2
Hau, C.W.3
Zhang, W.4
Vila-Sanjurjo, A.5
Holton, J.M.6
Cate, J.H.7
-
16
-
-
0025737972
-
A functional pseudoknot in 16S ribosomal RNA
-
Powers T., and Noller H.F. A functional pseudoknot in 16S ribosomal RNA. EMBO J. 10 (1991) 2203-2214
-
(1991)
EMBO J.
, vol.10
, pp. 2203-2214
-
-
Powers, T.1
Noller, H.F.2
-
17
-
-
0035805229
-
Recognition of cognate transfer RNA by the 30S ribosomal subunit
-
Ogle J.M., Brodersen D.E., Clemons Jr. W.M., Tarry M.J., Carter A.P., and Ramakrishnan V. Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science 292 (2001) 897-902
-
(2001)
Science
, vol.292
, pp. 897-902
-
-
Ogle, J.M.1
Brodersen, D.E.2
Clemons Jr., W.M.3
Tarry, M.J.4
Carter, A.P.5
Ramakrishnan, V.6
-
18
-
-
0026703121
-
A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA
-
O'Connor M., Goringer H.U., and Dahlberg A.E. A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA. Nucleic Acids Res. 20 (1992) 4221-4227
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 4221-4227
-
-
O'Connor, M.1
Goringer, H.U.2
Dahlberg, A.E.3
-
19
-
-
0027253296
-
Functional effects of a G to U base change at position 530 in a highly conserved loop of Escherichia coli 16S RNA
-
Santer M., Santer U., Nurse K., Bakin A., Cunningham P., Zain M., et al. Functional effects of a G to U base change at position 530 in a highly conserved loop of Escherichia coli 16S RNA. Biochemistry 32 (1993) 5539-5547
-
(1993)
Biochemistry
, vol.32
, pp. 5539-5547
-
-
Santer, M.1
Santer, U.2
Nurse, K.3
Bakin, A.4
Cunningham, P.5
Zain, M.6
-
20
-
-
58549118714
-
Structural basis for cross-resistance to ribosomal PTC antibiotics
-
Davidovich C., Bashan A., and Yonath A. Structural basis for cross-resistance to ribosomal PTC antibiotics. Proc. Natl Acad. Sci. USA 105 (2008) 20665-20670
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 20665-20670
-
-
Davidovich, C.1
Bashan, A.2
Yonath, A.3
-
21
-
-
0026350074
-
Arginine-mediated RNA recognition: the arginine fork
-
Calnan B., Tidor B., Biancalana S., Hudson D., and Frankel A. Arginine-mediated RNA recognition: the arginine fork. Science 252 (1991) 1167-1171
-
(1991)
Science
, vol.252
, pp. 1167-1171
-
-
Calnan, B.1
Tidor, B.2
Biancalana, S.3
Hudson, D.4
Frankel, A.5
-
22
-
-
0032800593
-
Experimental models of protein-RNA interaction: isolation and analyses of tRNA(Phe) and U1 snRNA-binding peptides from bacteriophage display libraries
-
Agris P.F., Marchbank M.T., Newman W., Guenther R., Ingram P., Swallow J., et al. Experimental models of protein-RNA interaction: isolation and analyses of tRNA(Phe) and U1 snRNA-binding peptides from bacteriophage display libraries. J. Protein Chem. 18 (1999) 425-435
-
(1999)
J. Protein Chem.
, vol.18
, pp. 425-435
-
-
Agris, P.F.1
Marchbank, M.T.2
Newman, W.3
Guenther, R.4
Ingram, P.5
Swallow, J.6
-
23
-
-
0011791776
-
In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP-dependent protein kinase
-
Maller J.L., Kemp B.E., and Krebs E.G. In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP-dependent protein kinase. Proc. Natl Acad. Sci. USA 75 (1978) 248-251
-
(1978)
Proc. Natl Acad. Sci. USA
, vol.75
, pp. 248-251
-
-
Maller, J.L.1
Kemp, B.E.2
Krebs, E.G.3
-
24
-
-
0030590258
-
Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation
-
Tan G.T., DeBlasio A., and Mankin A.S. Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation. J. Mol. Biol. 261 (1996) 222-230
-
(1996)
J. Mol. Biol.
, vol.261
, pp. 222-230
-
-
Tan, G.T.1
DeBlasio, A.2
Mankin, A.S.3
-
25
-
-
0033584879
-
Resistance mutations in 23S rRNA identify the site of action of protein synthesis inhibitor, linezolid, in the ribosomal peptidyl transferase center
-
Kloss P., Xiong L., Shinabarger D.L., and Mankin A.S. Resistance mutations in 23S rRNA identify the site of action of protein synthesis inhibitor, linezolid, in the ribosomal peptidyl transferase center. J. Mol. Biol. 294 (1999) 93-101
-
(1999)
J. Mol. Biol.
, vol.294
, pp. 93-101
-
-
Kloss, P.1
Xiong, L.2
Shinabarger, D.L.3
Mankin, A.S.4
-
26
-
-
67651002917
-
Fluorescently-labeled ribosomes as a tool for analyzing antibiotic binding
-
Llano-Sotelo B., Hickerson R.P., Lancaster L., Noller H.F., and Mankin A.S. Fluorescently-labeled ribosomes as a tool for analyzing antibiotic binding. RNA 15 (2009) 1597-1604
-
(2009)
RNA
, vol.15
, pp. 1597-1604
-
-
Llano-Sotelo, B.1
Hickerson, R.P.2
Lancaster, L.3
Noller, H.F.4
Mankin, A.S.5
-
27
-
-
0033642214
-
In vitro reconstitution of 30S ribosomal subunits using complete set of recombinant proteins
-
Culver G.M., and Noller H.F. In vitro reconstitution of 30S ribosomal subunits using complete set of recombinant proteins. Methods Enzymol. 318 (2000) 446-460
-
(2000)
Methods Enzymol.
, vol.318
, pp. 446-460
-
-
Culver, G.M.1
Noller, H.F.2
-
28
-
-
0029028722
-
Structural changes in the 530 loop of Escherichia coli 16S rRNA in mutants with impaired translational fidelity
-
Van Ryk D.I., and Dahlberg A.E. Structural changes in the 530 loop of Escherichia coli 16S rRNA in mutants with impaired translational fidelity. Nucleic Acids Res. 23 (1995) 3563-3570
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3563-3570
-
-
Van Ryk, D.I.1
Dahlberg, A.E.2
-
29
-
-
0028138280
-
Interactions of a small RNA with antibiotic and RNA ligands of the 30S subunit
-
Purohit P., and Stern S. Interactions of a small RNA with antibiotic and RNA ligands of the 30S subunit. Nature 370 (1994) 659-662
-
(1994)
Nature
, vol.370
, pp. 659-662
-
-
Purohit, P.1
Stern, S.2
-
30
-
-
0030774277
-
The ribosome-in-pieces: binding of elongation factor EF-G to oligoribonucleotides that mimic the sarcin/ricin and thiostrepton domains of 23S ribosomal RNA
-
Munishkin A., and Wool I.G. The ribosome-in-pieces: binding of elongation factor EF-G to oligoribonucleotides that mimic the sarcin/ricin and thiostrepton domains of 23S ribosomal RNA. Proc. Natl Acad. Sci. USA 94 (1997) 12280-12284
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 12280-12284
-
-
Munishkin, A.1
Wool, I.G.2
-
31
-
-
0034733382
-
Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA: analysis of the stem nucleotides
-
Morosyuk S.V., Lee K., SantaLucia Jr. J., and Cunningham P.R. Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA: analysis of the stem nucleotides. J. Mol. Biol. 300 (2001) 113-126
-
(2001)
J. Mol. Biol.
, vol.300
, pp. 113-126
-
-
Morosyuk, S.V.1
Lee, K.2
SantaLucia Jr., J.3
Cunningham, P.R.4
-
32
-
-
0031252479
-
Structure of a conserved RNA component of the peptidyl transferase centre
-
Puglisi E.V., Green R., Noller H.F., and Puglisi J.D. Structure of a conserved RNA component of the peptidyl transferase centre. Nat. Struct. Biol. 4 (1997) 775-778
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 775-778
-
-
Puglisi, E.V.1
Green, R.2
Noller, H.F.3
Puglisi, J.D.4
-
33
-
-
0037439087
-
Structure of 23S rRNA hairpin 35 and its interaction with the tylosin-resistance methyltransferase RlmAII
-
Lebars I., Yoshizawa S., Stenholm A.R., Guittet E., Douthwaite S., and Fourmy D. Structure of 23S rRNA hairpin 35 and its interaction with the tylosin-resistance methyltransferase RlmAII. EMBO J. 22 (2003) 183-192
-
(2003)
EMBO J.
, vol.22
, pp. 183-192
-
-
Lebars, I.1
Yoshizawa, S.2
Stenholm, A.R.3
Guittet, E.4
Douthwaite, S.5
Fourmy, D.6
-
34
-
-
33746879536
-
Peptides and peptidomimetics in medicine, surgery and biotechnology
-
Gentilucci L., Tolomelli A., and Squassabia F. Peptides and peptidomimetics in medicine, surgery and biotechnology. Curr. Med. Chem. 13 (2006) 2449-2466
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 2449-2466
-
-
Gentilucci, L.1
Tolomelli, A.2
Squassabia, F.3
|