Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp.

Biochemistry

Volumn 45, Issue 11, 2006, Pages 3692-3702

  Brandi, Letizia ^b,d   Lazzarini, Ameriga ^a   Cavaletti, Linda ^b   Abbondi, Monica ^a   Corti, Emiliana ^a   Ciciliato, Ismaela ^a   Gastaldo, Luciano ^a   Marazzi, Alessandra ^a   Feroggio, Marina ^a   Fabbretti, Attilio ^d   Maio, Alessandro ^d   Colombo, Luigi ^a   Donadio, Stefano ^b   Marinelli, Flavia ^a,c   Losi, Daniele ^a   Gualerzi, Claudio O ^d   Selva, Enrico ^a  

^a Vicuron Pharmaceuticals   (Italy)

^b Vicuron Pharmaceuticals   (Italy)

^c UNIVERSITY OF INSUBRIA   (Italy)

^d UNIVERSITY OF CAMERINO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOASSAY; CELLS; RNA; SPECTROSCOPIC ANALYSIS; SYNTHESIS (CHEMICAL);

CHEMICAL STRUCTURES; MICROBIAL PRODUCT SCREENING; PROTEIN SYNTHESIS; TETRAPEPTIDES;

PROTEINS;

ANTIBIOTIC AGENT; BLASTICIDIN S; BORRELIDIN; CARBOMYCIN; CHLORAMPHENICOL; ERYTHROMYCIN; FUSIDIC ACID; GE 2270; GE 2270A; GE 81112 A; GE 81112 B; GE 81112 B1; GENTAMICIN; KASUGAMYCIN; LINCOMYCIN; MESSENGER RNA; MOCIMYCIN; NEOMYCIN; NOSIHEPTIDE; PACTAMYCIN; PAROMOMYCIN; PROTEIN SYNTHESIS INHIBITOR; PSEUDOMONIC ACID; RIBOSOME PROTEIN; SPARSOMYCIN; STREPTOMYCIN; TETRACYCLINE; TETRAPEPTIDE; TETRAPEPTIDE INHIBITOR; THIOSTREPTON; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINO ACID SEQUENCE; ANTIBIOTIC SENSITIVITY; ARTICLE; DRUG DESIGN; DRUG DETERMINATION; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STREPTOMYCES; STRUCTURE ANALYSIS;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; BACTERIAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ESCHERICHIA COLI; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PEPTIDES; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES; RNA, MESSENGER; STREPTOMYCES; TIME FACTORS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; STREPTOMYCES; STREPTOMYCES SP.;

EID: 33645227437     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052540k     Document Type: Article

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