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Volumn 14, Issue 8, 2009, Pages 950-960

Inhibitor of apoptosis proteins in Drosophila: Gatekeepers of death

Author keywords

Apoptosis; Caspase; Drosophila; Inhibitor of apoptosis protein; Ubiquitin

Indexed keywords

CASPASE; INHIBITOR OF APOPTOSIS PROTEIN; UBIQUITIN PROTEIN LIGASE E3;

EID: 68149157524     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0358-2     Document Type: Article
Times cited : (87)

References (83)
  • 2
    • 0034305744 scopus 로고    scopus 로고
    • The Drosophila caspase Dredd is required to resist gram-negative bacterial infection
    • 10.1093/embo-reports/kvd073
    • F Leulier A Rodriguez RS Khush JM Abrams B Lemaitre 2000 The Drosophila caspase Dredd is required to resist gram-negative bacterial infection EMBO Rep 1 353 358 10.1093/embo-reports/kvd073
    • (2000) EMBO Rep , vol.1 , pp. 353-358
    • Leulier, F.1    Rodriguez, A.2    Khush, R.S.3    Abrams, J.M.4    Lemaitre, B.5
  • 3
    • 10644290827 scopus 로고    scopus 로고
    • The apical caspase dronc governs programmed and unprogrammed cell death in drosophila
    • DOI 10.1016/j.devcel.2004.09.016, PII S1534580704003648
    • SK Chew F Akdemir P Chen WJ Lu K Mills T Daish S Kumar A Rodriguez JM Abrams 2004 The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila Dev Cell 7 897 907 10.1016/j.devcel.2004.09.016 (Pubitemid 39654733)
    • (2004) Developmental Cell , vol.7 , Issue.6 , pp. 897-907
    • Chew, S.K.1    Akdemir, F.2    Chen, P.3    Lu, W.-J.4    Mills, K.5    Daish, T.6    Kumar, S.7    Rodriguez, A.8    Abrams, J.M.9
  • 4
    • 10644288480 scopus 로고    scopus 로고
    • Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis
    • DOI 10.1016/j.devcel.2004.09.018, PII S1534580704003740
    • TJ Daish K Mills S Kumar 2004 Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis Dev Cell 7 909 915 10.1016/j.devcel.2004.09.018 (Pubitemid 39654734)
    • (2004) Developmental Cell , vol.7 , Issue.6 , pp. 909-915
    • Daish, T.J.1    Mills, K.2    Kumar, S.3
  • 5
    • 19444366944 scopus 로고    scopus 로고
    • The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila
    • DOI 10.1242/dev.01790
    • D Xu Y Li M Arcaro M Lackey A Bergmann 2005 The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila Development 132 2125 2134 10.1242/dev.01790 (Pubitemid 40744472)
    • (2005) Development , vol.132 , Issue.9 , pp. 2125-2134
    • Xu, D.1    Li, Y.2    Arcaro, M.3    Lackey, M.4    Bergmann, A.5
  • 6
    • 45449093594 scopus 로고    scopus 로고
    • Regulation of apoptosis in Drosophila
    • DOI 10.1038/cdd.2008.50, PII CDD200850, Special Issue to celebrate Richard Lockshin's 70th Birthday
    • H Steller 2008 Regulation of apoptosis in Drosophila Cell Death Differ 15 1132 1138 10.1038/cdd.2008.50 (Pubitemid 351850965)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.7 , pp. 1132-1138
    • Steller, H.1
  • 7
    • 0030683619 scopus 로고    scopus 로고
    • DrlCE is an essential caspase required for apoptotic activity in Drosophila cells
    • DOI 10.1093/emboj/16.20.6192
    • AG Fraser NJ [tmp] McCarthy GI Evan 1997 drICE is an essential caspase required for apoptotic activity in Drosophila cells EMBO J 16 6192 6199 10.1093/emboj/16.20.6192 (Pubitemid 27458339)
    • (1997) EMBO Journal , vol.16 , Issue.20 , pp. 6192-6199
    • Fraser, A.G.1    McCarthy, N.J.2    Evan, G.I.3
  • 8
    • 33749392341 scopus 로고    scopus 로고
    • The Drosphila caspase lce is importance for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process
    • DOI 10.1242/dev.02495
    • I Muro DL Berry JR Huh CH Chen H Huang SJ Yoo M Guo EH Baehrecke BA Hay 2006 The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process Development 133 3305 3315 10.1242/dev.02495 (Pubitemid 44501833)
    • (2006) Development , vol.133 , Issue.17 , pp. 3305-3315
    • Muro, I.1    Berry, D.L.2    Huh, J.R.3    Chen, C.H.4    Huang, H.5    Yoo, S.J.6    Guo, M.7    Baehrecke, E.H.8    Hay, B.A.9
  • 9
    • 33748676654 scopus 로고    scopus 로고
    • The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila
    • DOI 10.1038/sj.cdd.4401920, PII 4401920
    • D Xu Y Wang R Willecke Z Chen T Ding A Bergmann 2006 The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila Cell Death Differ 13 1697 1706 10.1038/sj.cdd.4401920 (Pubitemid 44390857)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.10 , pp. 1697-1706
    • Xu, D.1    Wang, Y.2    Willecke, R.3    Chen, Z.4    Ding, T.5    Bergmann, A.6
  • 10
    • 39449094293 scopus 로고    scopus 로고
    • A biochemical analysis of the activation of the Drosophila caspase DRONC
    • DOI 10.1038/sj.cdd.4402288, PII 4402288
    • L Dorstyn S Kumar 2008 A biochemical analysis of the activation of the Drosophila caspase DRONC Cell Death Differ 15 461 470 10.1038/sj.cdd.4402288 (Pubitemid 351267297)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.3 , pp. 461-470
    • Dorstyn, L.1    Kumar, S.2
  • 11
    • 42149169031 scopus 로고    scopus 로고
    • Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC
    • 10.1038/cdd.2008.23
    • SJ Snipas M Drag HR Stennicke GS Salvesen 2008 Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC Cell Death Differ 15 938 945 10.1038/cdd.2008.23
    • (2008) Cell Death Differ , vol.15 , pp. 938-945
    • Snipas, S.J.1    Drag, M.2    Stennicke, H.R.3    Salvesen, G.S.4
  • 14
    • 33646839270 scopus 로고    scopus 로고
    • Structure and activation mechanism of the Drosophila initiator caspase Dronc
    • DOI 10.1074/jbc.M513232200
    • N Yan JR Huh V Schirf B Demeler BA Hay Y Shi 2006 Structure and activation mechanism of the Drosophila initiator caspase Dronc J Biol Chem 281 8667 8674 10.1074/jbc.M513232200 (Pubitemid 43847971)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.13 , pp. 8667-8674
    • Yan, N.1    Huh, J.R.2    Schirf, V.3    Demeler, B.4    Hay, B.A.5    Shi, Y.6
  • 15
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • DOI 10.1038/nrm1496
    • SJ Riedl Y Shi 2004 Molecular mechanisms of caspase regulation during apoptosis Nat Rev Mol Cell Biol 5 897 907 10.1038/nrm1496 (Pubitemid 39486541)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.11 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 16
    • 43249114217 scopus 로고    scopus 로고
    • Caspase mechanisms
    • 10.1007/978-1-4020-6554-5-2
    • GS Salvesen SJ Riedl 2008 Caspase mechanisms Adv Exp Med Biol 615 13 23 10.1007/978-1-4020-6554-5-2
    • (2008) Adv Exp Med Biol , vol.615 , pp. 13-23
    • Salvesen, G.S.1    Riedl, S.J.2
  • 17
    • 0027537461 scopus 로고
    • An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
    • NE Crook RJ Clem LK Miller 1993 An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif J Virol 67 2168 2174
    • (1993) J Virol , vol.67 , pp. 2168-2174
    • Crook, N.E.1    Clem, R.J.2    Miller, L.K.3
  • 18
    • 0034651791 scopus 로고    scopus 로고
    • Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
    • 10.1093/emboj/19.4.589
    • L Goyal K [tmp] McCall J Agapite E Hartwieg H Steller 2000 Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function EMBO J 19 589 597 10.1093/emboj/19.4.589
    • (2000) EMBO J , vol.19 , pp. 589-597
    • Goyal, L.1    McCall, K.2    Agapite, J.3    Hartwieg, E.4    Steller, H.5
  • 19
    • 0033980888 scopus 로고    scopus 로고
    • Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila
    • S Lisi I Mazzon K White 2000 Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila Genetics 154 669 678
    • (2000) Genetics , vol.154 , pp. 669-678
    • Lisi, S.1    Mazzon, I.2    White, K.3
  • 20
    • 0033588273 scopus 로고    scopus 로고
    • The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
    • DOI 10.1016/S0092-8674(00)81974-1
    • SL Wang CJ Hawkins SJ Yoo HA Muller BA Hay 1999 The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID Cell 98 453 463 10.1016/S0092-8674(00)81974-1 (Pubitemid 29402483)
    • (1999) Cell , vol.98 , Issue.4 , pp. 453-463
    • Wang, S.L.1    Hawkins, C.J.2    Yoo, S.J.3    Muller, H.-A.J.4    Hay, B.A.5
  • 22
    • 43049091895 scopus 로고    scopus 로고
    • IAPs: What's in a Name?
    • DOI 10.1016/j.molcel.2008.03.008, PII S1097276508002086
    • SM Srinivasula JD Ashwell 2008 IAPs: what's in a name? Mol Cell 30 123 135 10.1016/j.molcel.2008.03.008 (Pubitemid 351626688)
    • (2008) Molecular Cell , vol.30 , Issue.2 , pp. 123-135
    • Srinivasula, S.M.1    Ashwell, J.D.2
  • 23
    • 0037046814 scopus 로고    scopus 로고
    • Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death
    • DOI 10.1016/S0960-9822(02)00935-1, PII S0960982202009351
    • SY Vernooy V Chow J Su K Verbrugghe J Yang S Cole MR Olson BA Hay 2002 Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death Curr Biol 12 1164 1168 10.1016/S0960-9822(02)00935-1 (Pubitemid 34766942)
    • (2002) Current Biology , vol.12 , Issue.13 , pp. 1164-1168
    • Vernooy, S.Y.1    Chow, V.2    Su, J.3    Verbrugghe, K.4    Yang, J.5    Cole, S.6    Olson, M.R.7    Hay, B.A.8
  • 24
    • 0034710156 scopus 로고    scopus 로고
    • Cell death regulation in Drosophila: Conservation of mechanism and unique insights
    • 10.1083/jcb.150.2.F69
    • SY Vernooy J Copeland N Ghaboosi EE Griffin SJ Yoo BA Hay 2000 Cell death regulation in Drosophila: conservation of mechanism and unique insights J Cell Biol 150 F69 F76 10.1083/jcb.150.2.F69
    • (2000) J Cell Biol , vol.150
    • Vernooy, S.Y.1    Copeland, J.2    Ghaboosi, N.3    Griffin, E.E.4    Yoo, S.J.5    Hay, B.A.6
  • 25
    • 0034698097 scopus 로고    scopus 로고
    • Deterin, a new inhibitor of apoptosis from Drosophila melanogaster
    • DOI 10.1074/jbc.M000369200
    • G Jones D Jones L Zhou H Steller Y Chu 2000 Deterin, a new inhibitor of apoptosis from Drosophila melanogaster J Biol Chem 275 22157 22165 10.1074/jbc.M000369200 (Pubitemid 30621796)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.29 , pp. 22157-22165
    • Jones, G.1    Jones, D.2    Zhou, L.3    Steller, H.4    Chu, Y.5
  • 26
    • 0033057366 scopus 로고    scopus 로고
    • A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1
    • DOI 10.1073/pnas.96.6.2885
    • CJ Hawkins SL Wang BA Hay 1999 A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1 Proc Natl Acad Sci USA 96 2885 2890 10.1073/pnas.96.6.2885 (Pubitemid 29148813)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.6 , pp. 2885-2890
    • Hawkins, C.J.1    Wang, S.L.2    Hay, B.A.3
  • 27
    • 0032573595 scopus 로고    scopus 로고
    • The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE
    • DOI 10.1016/S0014-5793(98)01465-3, PII S0014579398014653
    • WJ Kaiser D Vucic LK Miller 1998 The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE FEBS Lett 440 243 248 10.1016/S0014-5793(98)01465-3 (Pubitemid 28558774)
    • (1998) FEBS Letters , vol.440 , Issue.1-2 , pp. 243-248
    • Kaiser, W.J.1    Vucic, D.2    Miller, L.K.3
  • 28
    • 0345732684 scopus 로고    scopus 로고
    • IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding
    • DOI 10.1093/emboj/cdg617
    • A Zachariou T Tenev L Goyal J Agapite H Steller P Meier 2003 IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding EMBO J 22 6642 6652 10.1093/emboj/cdg617 (Pubitemid 38009610)
    • (2003) EMBO Journal , vol.22 , Issue.24 , pp. 6642-6652
    • Zachariou, A.1    Tenev, T.2    Goyal, L.3    Agapite, J.4    Steller, H.5    Meier, P.6
  • 29
    • 0034651987 scopus 로고    scopus 로고
    • The Drosophila caspase DRONC is regulated by DIAP1
    • 10.1093/emboj/19.4.598
    • P Meier J Silke SJ Leevers GI Evan 2000 The Drosophila caspase DRONC is regulated by DIAP1 EMBO J 19 598 611 10.1093/emboj/19.4.598
    • (2000) EMBO J , vol.19 , pp. 598-611
    • Meier, P.1    Silke, J.2    Leevers, S.J.3    Evan, G.I.4
  • 30
    • 0036566395 scopus 로고    scopus 로고
    • Unrestrained caspase-dependent cell death caused by loss of Diap 1 function requires the Drosophila Apaf-1 homolog, Dark
    • DOI 10.1093/emboj/21.9.2189
    • A Rodriguez P Chen H Oliver JM Abrams 2002 Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark EMBO J 21 2189 2197 10.1093/emboj/21.9.2189 (Pubitemid 34516778)
    • (2002) EMBO Journal , vol.21 , Issue.9 , pp. 2189-2197
    • Rodriguez, A.1    Chen, P.2    Oliver, H.3    Abrams, J.M.4
  • 31
    • 12344300349 scopus 로고    scopus 로고
    • IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
    • DOI 10.1038/ncb1204
    • T Tenev A Zachariou R Wilson M Ditzel P Meier 2005 IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms Nat Cell Biol 7 70 77 10.1038/ncb1204 (Pubitemid 40123385)
    • (2005) Nature Cell Biology , vol.7 , Issue.1 , pp. 70-77
    • Tencho, T.1    Zachariou, A.2    Wilson, R.3    Ditzel, M.4    Meier, P.5
  • 32
    • 0034700491 scopus 로고    scopus 로고
    • Structural basis of IAP recognition by Smac/DIABLO
    • DOI 10.1038/35050012
    • G Wu J Chai TL Suber JW Wu C Du X Wang Y Shi 2000 Structural basis of IAP recognition by Smac/DIABLO Nature 408 1008 1012 10.1038/35050012 (Pubitemid 32101651)
    • (2000) Nature , vol.408 , Issue.6815 , pp. 1008-1012
    • Wu, G.1    Chai, J.2    Suber, T.L.3    Wu, J.-W.4    Du, C.5    Wang, X.6    Shi, Y.7
  • 33
    • 0034886271 scopus 로고    scopus 로고
    • Structural analysis of a functional DIAP1 fragment bound to Grim and Hid peptides
    • DOI 10.1016/S1097-2765(01)00282-9
    • JW Wu AE Cocina J Chai BA Hay Y Shi 2001 Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides Mol Cell 8 95 104 10.1016/S1097-2765(01)00282-9 (Pubitemid 32772908)
    • (2001) Molecular Cell , vol.8 , Issue.1 , pp. 95-104
    • Wu, J.-W.1    Cocina, A.E.2    Chai, J.3    Hay, B.A.4    Shi, Y.5
  • 34
    • 0242574748 scopus 로고    scopus 로고
    • Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination
    • DOI 10.1038/nsb989
    • J Chai N Yan JR Huh JW Wu W Li BA Hay Y Shi 2003 Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination Nat Struct Biol 10 892 898 10.1038/nsb989 (Pubitemid 37386097)
    • (2003) Nature Structural Biology , vol.10 , Issue.11 , pp. 892-898
    • Chai, J.1    Yan, N.2    Huh, J.R.3    Wu, J.-W.4    Li, W.5    Hay, B.A.6    Shi, Y.7
  • 35
    • 0034296394 scopus 로고    scopus 로고
    • The ubiquitin system
    • DOI 10.1038/80384
    • A Hershko A Ciechanover A Varshavsky 2000 Basic medical research award. The ubiquitin system Nat Med 6 1073 1081 10.1038/80384 (Pubitemid 30792176)
    • (2000) Nature Medicine , vol.6 , Issue.10 , pp. 1073-1081
    • Hershko, A.1    Ciechanover, A.2    Varshavsky, A.3
  • 36
    • 27144529182 scopus 로고    scopus 로고
    • Ubiquitylation and cell signaling
    • DOI 10.1038/sj.emboj.7600808, PII 7600808
    • K Haglund I Dikic 2005 Ubiquitylation and cell signaling EMBO J 24 3353 3359 10.1038/sj.emboj.7600808 (Pubitemid 41486773)
    • (2005) EMBO Journal , vol.24 , Issue.19 , pp. 3353-3359
    • Haglund, K.1    Dikic, I.2
  • 38
    • 33748991453 scopus 로고    scopus 로고
    • Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
    • DOI 10.1038/nrc1994, PII NRC1994
    • D Hoeller CM Hecker I Dikic 2006 Ubiquitin and ubiquitin-like proteins in cancer pathogenesis Nat Rev Cancer 6 776 788 10.1038/nrc1994 (Pubitemid 44450466)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.10 , pp. 776-788
    • Hoeller, D.1    Hecker, C.-M.2    Dikic, I.3
  • 40
    • 0036300214 scopus 로고    scopus 로고
    • The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis
    • DOI 10.1038/ncb799
    • R Wilson L Goyal M Ditzel A Zachariou DA Baker J Agapite H Steller P Meier 2002 The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis Nat Cell Biol 4 445 450 10.1038/ncb799 (Pubitemid 34746163)
    • (2002) Nature Cell Biology , vol.4 , Issue.6 , pp. 445-450
    • Wilson, R.1    Goyal, L.2    Ditzel, M.3    Zachariou, A.4    Baker, D.A.5    Agapite, J.6    Steller, H.7    Meier, P.8
  • 41
    • 57049143644 scopus 로고    scopus 로고
    • Regulation of the Drosophila apoptosome through feedback inhibition
    • 10.1038/ncb1803
    • PJ Shapiro HH Hsu H Jung ES Robbins HD Ryoo 2008 Regulation of the Drosophila apoptosome through feedback inhibition Nat Cell Biol 10 1440 1446 10.1038/ncb1803
    • (2008) Nat Cell Biol , vol.10 , pp. 1440-1446
    • Shapiro, P.J.1    Hsu, H.H.2    Jung, H.3    Robbins, E.S.4    Ryoo, H.D.5
  • 42
    • 0346668315 scopus 로고    scopus 로고
    • The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC
    • DOI 10.1074/jbc.M203464200
    • I Muro BA Hay RJ Clem 2002 The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC J Biol Chem 277 49644 49650 10.1074/jbc.M203464200 (Pubitemid 36014406)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49644-49650
    • Muro, I.1    Hay, B.A.2    Clem, R.J.3
  • 43
    • 33947384611 scopus 로고    scopus 로고
    • Regulation of the Drosophila ubiquitin ligase DIAP1 is mediated via several distinct ubiquitin system pathways
    • DOI 10.1038/sj.cdd.4402079, PII 4402079
    • Y Herman-Bachinsky HD Ryoo A Ciechanover H Gonen 2007 Regulation of the Drosophila ubiquitin ligase DIAP1 is mediated via several distinct ubiquitin system pathways Cell Death Differ 14 861 871 10.1038/sj.cdd.4402079 (Pubitemid 46444523)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.4 , pp. 861-871
    • Herman-Bachinsky, Y.1    Ryoo, H.-D.2    Ciechanover, A.3    Gonen, H.4
  • 44
    • 2342617566 scopus 로고    scopus 로고
    • Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim
    • DOI 10.1038/nsmb764
    • N Yan JW Wu J Chai W Li Y Shi 2004 Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim Nat Struct Mol Biol 11 420 428 10.1038/nsmb764 (Pubitemid 38568945)
    • (2004) Nature Structural and Molecular Biology , vol.11 , Issue.5 , pp. 420-428
    • Yan, N.1    Wu, J.-W.2    Chai, J.3    Li, W.4    Shi, Y.5
  • 45
    • 0037936841 scopus 로고    scopus 로고
    • Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis
    • DOI 10.1038/ncb984
    • M Ditzel R Wilson T Tenev A Zachariou A Paul E Deas P Meier 2003 Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis Nat Cell Biol 5 467 473 10.1038/ncb984 (Pubitemid 36592271)
    • (2003) Nature Cell Biology , vol.5 , Issue.5 , pp. 467-473
    • Ditzel, M.1    Wilson, R.2    Tenev, T.3    Zachariou, A.4    Paul, A.5    Deas, E.6    Meier, P.7
  • 46
    • 21444436375 scopus 로고    scopus 로고
    • Cleavage of the apoptosis inhibitor DIAP1 by the apical caspase DRONC in both normal and apoptotic Drosophila cells
    • DOI 10.1074/jbc.M501206200
    • I Muro JC Means RJ Clem 2005 Cleavage of the apoptosis inhibitor DIAP1 by the apical caspase DRONC in both normal and apoptotic Drosophila cells J Biol Chem 280 18683 18688 10.1074/jbc.M501206200 (Pubitemid 41379568)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.19 , pp. 18683-18688
    • Muro, I.1    Means, J.C.2    Clem, R.J.3
  • 47
    • 38049016966 scopus 로고    scopus 로고
    • DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells
    • 10.1083/jcb.200706027
    • PS Ribeiro E Kuranaga T Tenev F Leulier M Miura P Meier 2007 DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells J Cell Biol 179 1467 1480 10.1083/jcb.200706027
    • (2007) J Cell Biol , vol.179 , pp. 1467-1480
    • Ribeiro, P.S.1    Kuranaga, E.2    Tenev, T.3    Leulier, F.4    Miura, M.5    Meier, P.6
  • 48
    • 0037128923 scopus 로고    scopus 로고
    • The role of ARK in stress-induced apoptosis in Drosophila cells
    • DOI 10.1083/jcb.20112068
    • KC Zimmermann JE Ricci NM Droin DR Green 2002 The role of ARK in stress-induced apoptosis in Drosophila cells J Cell Biol 156 1077 1087 10.1083/jcb.20112068 (Pubitemid 34839856)
    • (2002) Journal of Cell Biology , vol.156 , Issue.6 , pp. 1077-1087
    • Zimmermann, K.C.1    Ricci, J.-E.2    Droin, N.M.3    Green, D.R.4
  • 49
    • 0029583176 scopus 로고
    • Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death
    • DOI 10.1016/0092-8674(95)90150-7
    • BA Hay DA Wassarman GM Rubin 1995 Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death Cell 83 1253 1262 10.1016/0092-8674(95)90150-7 (Pubitemid 26007815)
    • (1995) Cell , vol.83 , Issue.7 , pp. 1253-1262
    • Hay, B.A.1    Wassarman, D.A.2    Rubin, G.M.3
  • 51
    • 19344368275 scopus 로고    scopus 로고
    • Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization
    • DOI 10.1371/journal.pbio.0020015
    • JR Huh SY Vernooy H Yu N Yan Y Shi M Guo BA Hay 2004 Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization PLoS Biol 2 E15 10.1371/journal.pbio.0020015 (Pubitemid 39234585)
    • (2004) PLoS Biology , vol.2 , Issue.1
    • Huh, J.R.1    Vernooy, S.Y.2    Yu, H.3    Yan, N.4    Shi, Y.5    Guo, M.6    Hay, B.A.7
  • 52
    • 0037654554 scopus 로고    scopus 로고
    • Caspase activity and a specific cytochrome C are required for sperm differentiation in Drosophila
    • DOI 10.1016/S1534-5807(03)00120-5, PII S1534580703001205
    • E Arama J Agapite H Steller 2003 Caspase activity and a specific cytochrome C are required for sperm differentiation in Drosophila Dev Cell 4 687 697 10.1016/S1534-5807(03)00120-5 (Pubitemid 36564899)
    • (2003) Developmental Cell , vol.4 , Issue.5 , pp. 687-697
    • Arama, E.1    Agapite, J.2    Steller, H.3
  • 53
    • 52249085861 scopus 로고    scopus 로고
    • Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis
    • 10.1083/jcb.200712091
    • YC Hou S Chittaranjan SG Barbosa K [tmp] McCall SM Gorski 2008 Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis J Cell Biol 182 1127 1139 10.1083/jcb.200712091
    • (2008) J Cell Biol , vol.182 , pp. 1127-1139
    • Hou, Y.C.1    Chittaranjan, S.2    Barbosa, S.G.3    McCall, K.4    Gorski, S.M.5
  • 54
    • 0034993758 scopus 로고    scopus 로고
    • Two kinds of BIR-containing protein - Inhibitors of apoptosis, or required for mitosis
    • J Silke DL Vaux 2001 Two kinds of BIR-containing protein - inhibitors of apoptosis, or required for mitosis J Cell Sci 114 1821 1827
    • (2001) J Cell Sci , vol.114 , pp. 1821-1827
    • Silke, J.1    Vaux, D.L.2
  • 55
  • 56
    • 0037154014 scopus 로고    scopus 로고
    • The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from Reaper, Grim, and Hid
    • DOI 10.1016/S0960-9822(01)00658-3, PII S0960982201006583
    • A Christich S Kauppila P Chen N Sogame SI Ho JM Abrams 2002 The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid Curr Biol 12 137 140 10.1016/S0960-9822(01)00658-3 (Pubitemid 34099138)
    • (2002) Current Biology , vol.12 , Issue.2 , pp. 137-140
    • Christich, A.1    Kauppila, S.2    Chen, P.3    Sogame, N.4    Ho, S.-I.5    Abrams, J.M.6
  • 57
    • 0037154009 scopus 로고    scopus 로고
    • Drosophila sickle is a novel grim-reaper cell death activator
    • DOI 10.1016/S0960-9822(01)00664-9, PII S0960982201006649
    • JP Wing JS Karres JL Ogdahl L Zhou LM Schwartz JR Nambu 2002 Drosophila sickle is a novel grim-reaper cell death activator Curr Biol 12 131 135 10.1016/S0960-9822(01)00664-9 (Pubitemid 34099137)
    • (2002) Current Biology , vol.12 , Issue.2 , pp. 131-135
    • Wing, J.P.1    Karres, J.S.2    Ogdahl, J.L.3    Zhou, L.4    Schwartz, L.M.5    Nambu, J.R.6
  • 58
    • 0036791634 scopus 로고    scopus 로고
    • Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
    • 10.1093/emboj/cdf530
    • T Tenev A Zachariou R Wilson A Paul P Meier 2002 Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1 EMBO J 21 5118 5129 10.1093/emboj/cdf530
    • (2002) EMBO J , vol.21 , pp. 5118-5129
    • Tenev, T.1    Zachariou, A.2    Wilson, R.3    Paul, A.4    Meier, P.5
  • 59
    • 0031572768 scopus 로고    scopus 로고
    • Genes that induce apoptosis: Transcriptional regulation in identified, doomed neurons of the Drosophila CNS
    • DOI 10.1006/dbio.1997.8696
    • S Robinow TA Draizen JW Truman 1997 Genes that induce apoptosis: transcriptional regulation in identified, doomed neurons of the Drosophila CNS Dev Biol 190 206 213 10.1006/dbio.1997.8696 (Pubitemid 27488106)
    • (1997) Developmental Biology , vol.190 , Issue.2 , pp. 206-213
    • Robinow, S.1    Draizen, T.A.2    Truman, J.W.3
  • 60
    • 0031738898 scopus 로고    scopus 로고
    • Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes
    • 10.1038/sj.cdd.4400423
    • JP Wing L Zhou LM Schwartz JR Nambu 1998 Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes Cell Death Differ 5 930 939 10.1038/sj.cdd.4400423
    • (1998) Cell Death Differ , vol.5 , pp. 930-939
    • Wing, J.P.1    Zhou, L.2    Schwartz, L.M.3    Nambu, J.R.4
  • 62
    • 0035831022 scopus 로고    scopus 로고
    • Structural basis of caspase inhibition by XIAP: Differential roles of the linker versus the BIR domain
    • Y Huang YC Park RL Rich D Segal DG Myszka H Wu 2001 Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain Cell 104 781 790
    • (2001) Cell , vol.104 , pp. 781-790
    • Huang, Y.1    Park, Y.C.2    Rich, R.L.3    Segal, D.4    Myszka, D.G.5    Wu, H.6
  • 63
    • 0036307854 scopus 로고    scopus 로고
    • Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1
    • DOI 10.1038/ncb794
    • R Hays L Wickline R Cagan 2002 Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1 Nat Cell Biol 4 425 431 10.1038/ncb794 (Pubitemid 34746160)
    • (2002) Nature Cell Biology , vol.4 , Issue.6 , pp. 425-431
    • Hays, R.1    Wickline, L.2    Cagan, R.3
  • 64
    • 0036303143 scopus 로고    scopus 로고
    • Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition
    • DOI 10.1038/ncb798
    • CL Holley MR Olson DA Colon-Ramos S Kornbluth 2002 Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition Nat Cell Biol 4 439 444 10.1038/ncb798 (Pubitemid 34746162)
    • (2002) Nature Cell Biology , vol.4 , Issue.6 , pp. 439-444
    • Holley, C.L.1    Olson, M.R.2    Colon-Ramos, D.A.3    Kornbluth, S.4
  • 65
    • 0036300083 scopus 로고    scopus 로고
    • Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
    • DOI 10.1038/ncb795
    • HD Ryoo A Bergmann H Gonen A Ciechanover H Steller 2002 Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1 Nat Cell Biol 4 432 438 10.1038/ncb795 (Pubitemid 34746161)
    • (2002) Nature Cell Biology , vol.4 , Issue.6 , pp. 432-438
    • Ryoo, H.D.1    Bergmann, A.2    Gonen, H.3    Ciechanover, A.4    Steller, H.5
  • 68
    • 33746570157 scopus 로고    scopus 로고
    • Drosophila IKK-Related Kinase Regulates Nonapoptotic Function of Caspases via Degradation of IAPs
    • DOI 10.1016/j.cell.2006.05.048, PII S0092867406009093
    • E Kuranaga H Kanuka A Tonoki K Takemoto T Tomioka M Kobayashi S Hayashi M Miura 2006 Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs Cell 126 583 596 10.1016/j.cell.2006.05.048 (Pubitemid 44163604)
    • (2006) Cell , vol.126 , Issue.3 , pp. 583-596
    • Kuranaga, E.1    Kanuka, H.2    Tonoki, A.3    Takemoto, K.4    Tomioka, T.5    Kobayashi, M.6    Hayashi, S.7    Miura, M.8
  • 69
    • 33746574519 scopus 로고    scopus 로고
    • IKKε Regulates F Actin Assembly and Interacts with Drosophila IAP1 in Cellular Morphogenesis
    • DOI 10.1016/j.cub.2006.06.032, PII S0960982206017507
    • K Oshima M Takeda E Kuranaga R Ueda T Aigaki M Miura S Hayashi 2006 IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis Curr Biol 16 1531 1537 10.1016/j.cub.2006.06.032 (Pubitemid 44142978)
    • (2006) Current Biology , vol.16 , Issue.15 , pp. 1531-1537
    • Oshima, K.1    Takeda, M.2    Kuranaga, E.3    Ueda, R.4    Aigaki, T.5    Miura, M.6    Hayashi, S.7
  • 70
    • 34247191134 scopus 로고    scopus 로고
    • Hippo signaling in organ size control
    • DOI 10.1101/gad.1536007
    • D Pan 2007 Hippo signaling in organ size control Genes Dev 21 886 897 10.1101/gad.1536007 (Pubitemid 46625638)
    • (2007) Genes and Development , vol.21 , Issue.8 , pp. 886-897
    • Pan, D.1
  • 71
    • 42049103717 scopus 로고    scopus 로고
    • Yorkie and Scalloped: Partners in growth activation
    • 10.1016/j.devcel.2008.02.010
    • JL Bandura BA Edgar 2008 Yorkie and Scalloped: partners in growth activation Dev Cell 14 315 316 10.1016/j.devcel.2008.02.010
    • (2008) Dev Cell , vol.14 , pp. 315-316
    • Bandura, J.L.1    Edgar, B.A.2
  • 72
    • 34347396981 scopus 로고    scopus 로고
    • Down-regulation of inhibitor of apoptosis levels provides competence for steroid-triggered cell death
    • DOI 10.1083/jcb.200703206
    • VP Yin CS Thummel A Bashirullah 2007 Down-regulation of inhibitor of apoptosis levels provides competence for steroid-triggered cell death J Cell Biol 178 85 92 10.1083/jcb.200703206 (Pubitemid 47026404)
    • (2007) Journal of Cell Biology , vol.178 , Issue.1 , pp. 85-92
    • Yin, V.P.1    Thummel, C.S.2    Bashirullah, A.3
  • 73
    • 57649240267 scopus 로고    scopus 로고
    • Enhanced sensitivity of midline glial cells to apoptosis is achieved by HOW(L)-dependent repression of Diap1
    • 10.1016/j.mod.2008.10.004
    • A Reuveny H Elhanany T Volk 2009 Enhanced sensitivity of midline glial cells to apoptosis is achieved by HOW(L)-dependent repression of Diap1 Mech Dev 126 30 41 10.1016/j.mod.2008.10.004
    • (2009) Mech Dev , vol.126 , pp. 30-41
    • Reuveny, A.1    Elhanany, H.2    Volk, T.3
  • 74
    • 3142598843 scopus 로고    scopus 로고
    • A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration
    • DOI 10.1016/j.cell.2004.06.020, PII S0092867404006221
    • ER Geisbrecht DJ Montell 2004 A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration Cell 118 111 125 10.1016/j.cell.2004.06.020 (Pubitemid 38902818)
    • (2004) Cell , vol.118 , Issue.1 , pp. 111-125
    • Geisbrecht, E.R.1    Montell, D.J.2
  • 75
    • 27344453240 scopus 로고    scopus 로고
    • An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila
    • DOI 10.1038/sj.embor.7400530, PII 7400530
    • V Gesellchen D Kuttenkeuler M Steckel N Pelte M Boutros 2005 An RNA interference screen identifies inhibitor of apoptosis protein 2 as a regulator of innate immune signalling in Drosophila EMBO Rep 6 979 984 10.1038/sj.embor.7400530 (Pubitemid 41521955)
    • (2005) EMBO Reports , vol.6 , Issue.10 , pp. 979-984
    • Gesellchen, V.1    Kuttenkeuler, D.2    Steckel, M.3    Pelte, N.4    Boutros, M.5
  • 76
    • 33847273186 scopus 로고    scopus 로고
    • The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to Gram-negative bacterial infection, and can be negatively regulated by the Reaper/Hid/Grim family of IAP-binding apoptosis inducers
    • DOI 10.1074/jbc.M608051200
    • JR Huh I Foe I Muro CH Chen JH Seol SJ Yoo M Guo JM Park BA Hay 2007 The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers J Biol Chem 282 2056 2068 10.1074/jbc.M608051200 (Pubitemid 47076727)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.3 , pp. 2056-2068
    • Huh, J.R.1    Foe, I.2    Muro, I.3    Chun, H.C.4    Jae, H.S.5    Soon, J.Y.6    Guo, M.7    Jin, M.P.8    Hay, B.A.9
  • 78
    • 33750330952 scopus 로고    scopus 로고
    • The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection
    • DOI 10.1128/MCB.00548-06
    • F Leulier N Lhocine B Lemaitre P Meier 2006 The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection Mol Cell Biol 26 7821 7831 10.1128/MCB.00548-06 (Pubitemid 44630984)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.21 , pp. 7821-7831
    • Leulier, F.1    Lhocine, N.2    Lemaitre, B.3    Meier, P.4
  • 81
    • 54049155149 scopus 로고    scopus 로고
    • C-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
    • 10.1074/jbc.C800128200
    • E Varfolomeev T Goncharov AV Fedorova JN Dynek K Zobel K Deshayes WJ Fairbrother D Vucic 2008 c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation J Biol Chem 283 24295 24299 10.1074/jbc.C800128200
    • (2008) J Biol Chem , vol.283 , pp. 24295-24299
    • Varfolomeev, E.1    Goncharov, T.2    Fedorova, A.V.3    Dynek, J.N.4    Zobel, K.5    Deshayes, K.6    Fairbrother, W.J.7    Vucic, D.8


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