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Volumn 106, Issue 30, 2009, Pages 12211-12212

The spliceosome as ribozyme hypothesis takes a second step

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME;

EID: 68149147548     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906762106     Document Type: Note
Times cited : (16)

References (31)
  • 1
    • 0033792637 scopus 로고    scopus 로고
    • The question remains: Is the spliceosome a ribozyme?
    • Collins CA, Guthrie C (2000) The question remains: Is the spliceosome a ribozyme? Nat Struct Biol 7:850-854.
    • (2000) Nat Struct Biol , vol.7 , pp. 850-854
    • Collins, C.A.1    Guthrie, C.2
  • 2
    • 0036948420 scopus 로고    scopus 로고
    • Allosteric cascade of spliceosome activation
    • Brow DA (2002) Allosteric cascade of spliceosome activation. Annu Rev Genet 36:333-360.
    • (2002) Annu Rev Genet , vol.36 , pp. 333-360
    • Brow, D.A.1
  • 3
    • 0027488624 scopus 로고
    • Isolation of new ribozymes from a large pool of random sequences
    • Bartel DP, Szostak JW (1993) Isolation of new ribozymes from a large pool of random sequences. Science 261:1411-1418.
    • (1993) Science , vol.261 , pp. 1411-1418
    • Bartel, D.P.1    Szostak, J.W.2
  • 4
    • 58149086405 scopus 로고    scopus 로고
    • Identification and characterization of a short 2′-3′ bond-forming ribozyme
    • Smith DJ, Konarska MM (2009) Identification and characterization of a short 2′-3′ bond-forming ribozyme. RNA 15:8-13.
    • (2009) RNA , vol.15 , pp. 8-13
    • Smith, D.J.1    Konarska, M.M.2
  • 5
    • 58149099850 scopus 로고    scopus 로고
    • The use of simple model systems to study spliceosomal catalysis
    • Valadkhan S, Manley JL (2009) The use of simple model systems to study spliceosomal catalysis. RNA 15:4-7.
    • (2009) RNA , vol.15 , pp. 4-7
    • Valadkhan, S.1    Manley, J.L.2
  • 6
    • 58149088299 scopus 로고    scopus 로고
    • A critical assessment of the utility of protein-free splicing systems
    • Smith DJ, Konarska MM (2009) A critical assessment of the utility of protein-free splicing systems. RNA 15:1-3.
    • (2009) RNA , vol.15 , pp. 1-3
    • Smith, D.J.1    Konarska, M.M.2
  • 7
    • 67749098066 scopus 로고    scopus 로고
    • Protein-free small nuclear RNAs catalyze a two-step splicing reaction
    • Valadkhan S, Mohammadi A, Jaladat Y, Geisler S (2009) Protein-free small nuclear RNAs catalyze a two-step splicing reaction. Proc Natl Acad Sci USA 106:11901-11906.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11901-11906
    • Valadkhan, S.1    Mohammadi, A.2    Jaladat, Y.3    Geisler, S.4
  • 8
    • 36248936068 scopus 로고    scopus 로고
    • Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing
    • Valadkhan S, Mohammadi A, Wachtel C, Manley JL (2007) Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing. RNA 13:2300-2311.
    • (2007) RNA , vol.13 , pp. 2300-2311
    • Valadkhan, S.1    Mohammadi, A.2    Wachtel, C.3    Manley, J.L.4
  • 9
    • 0038719932 scopus 로고    scopus 로고
    • Characterization of the catalytic activity of U2 and U6 snRNAs
    • Valadkhan S, Manley JL (2003) Characterization of the catalytic activity of U2 and U6 snRNAs. RNA 9:892-904.
    • (2003) RNA , vol.9 , pp. 892-904
    • Valadkhan, S.1    Manley, J.L.2
  • 10
    • 0035909314 scopus 로고    scopus 로고
    • Splicing-related catalysis by protein-free snRNAs
    • Valadkhan S, Manley JL (2001) Splicing-related catalysis by protein-free snRNAs. Nature 413:701-707.
    • (2001) Nature , vol.413 , pp. 701-707
    • Valadkhan, S.1    Manley, J.L.2
  • 11
    • 0032568012 scopus 로고    scopus 로고
    • Group II intron splicing in vivo by first-step hydrolysis
    • Podar M, Chu VT, Pyle AM, Perlman PS (1998) Group II intron splicing in vivo by first-step hydrolysis. Nature 391:915-918.
    • (1998) Nature , vol.391 , pp. 915-918
    • Podar, M.1    Chu, V.T.2    Pyle, A.M.3    Perlman, P.S.4
  • 12
    • 0033965261 scopus 로고    scopus 로고
    • Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: Extending the parallels between the spliceosome and group II introns
    • Gordon PM, Sontheimer EJ, Piccirilli JA (2000) Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: Extending the parallels between the spliceosome and group II introns. RNA 6:199-205.
    • (2000) RNA , vol.6 , pp. 199-205
    • Gordon, P.M.1    Sontheimer, E.J.2    Piccirilli, J.A.3
  • 13
    • 41749109563 scopus 로고    scopus 로고
    • Crystal structure of a self-spliced group II intron
    • Toor N, Keating KS, Taylor SD, Pyle AM (2008) Crystal structure of a self-spliced group II intron. Science 320:77-82.
    • (2008) Science , vol.320 , pp. 77-82
    • Toor, N.1    Keating, K.S.2    Taylor, S.D.3    Pyle, A.M.4
  • 15
    • 0027184481 scopus 로고
    • A general two-metal-ion mechanism for catalytic RNA
    • Steitz TA, Steitz JA (1993) A general two-metal-ion mechanism for catalytic RNA. Proc Natl Acad Sci USA 90:6498-6502.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6498-6502
    • Steitz, T.A.1    Steitz, J.A.2
  • 16
  • 18
    • 0034649666 scopus 로고    scopus 로고
    • Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome
    • Yean SL, Wuenschell G, Termini J, Lin RJ (2000) Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature 408:881-884.
    • (2000) Nature , vol.408 , pp. 881-884
    • Yean, S.L.1    Wuenschell, G.2    Termini, J.3    Lin, R.J.4
  • 19
    • 57149111020 scopus 로고    scopus 로고
    • Is the spliceosome a ribonucleoprotein enzyme?
    • Abelson J (2008) Is the spliceosome a ribonucleoprotein enzyme? Nat Struct Mol Biol 15:1235-1237.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 1235-1237
    • Abelson, J.1
  • 20
    • 0034636956 scopus 로고    scopus 로고
    • Structural biology: The ribosome is a ribozyme
    • Cech TR (2000) Structural biology: The ribosome is a ribozyme. Science 289:878-879.
    • (2000) Science , vol.289 , pp. 878-879
    • Cech, T.R.1
  • 21
    • 0026639881 scopus 로고
    • Unusual resistance of peptidyl transferase to protein extraction procedures
    • Noller HF, Hoffarth V, Zimniak L (1992) Unusual resistance of peptidyl transferase to protein extraction procedures. Science 256:1416-1419.
    • (1992) Science , vol.256 , pp. 1416-1419
    • Noller, H.F.1    Hoffarth, V.2    Zimniak, L.3
  • 22
    • 0042671357 scopus 로고    scopus 로고
    • Pre-mRNA splicing: Awash in a sea of proteins
    • Jurica MS, Moore MJ (2003) Pre-mRNA splicing: Awash in a sea of proteins. Mol Cell 12:5-14.
    • (2003) Mol Cell , vol.12 , pp. 5-14
    • Jurica, M.S.1    Moore, M.J.2
  • 23
    • 0033179750 scopus 로고    scopus 로고
    • Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center
    • Siatecka M, Reyes JL, Konarska MM (1999) Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center. Genes Dev 13:1983-1993.
    • (1999) Genes Dev , vol.13 , pp. 1983-1993
    • Siatecka, M.1    Reyes, J.L.2    Konarska, M.M.3
  • 24
    • 0033053502 scopus 로고    scopus 로고
    • The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5′ splice site
    • Reyes JL, Gustafson EH, Luo HR, Moore MJ, Konarska MM (1999) The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5′ splice site. RNA 5:167-179.
    • (1999) RNA , vol.5 , pp. 167-179
    • Reyes, J.L.1    Gustafson, E.H.2    Luo, H.R.3    Moore, M.J.4    Konarska, M.M.5
  • 25
    • 55549143970 scopus 로고    scopus 로고
    • Structure and function of an RNase H domain at the heart of the spliceosome
    • Pena V, Rozov A, Fabrizio P, Luhrmann R, Wahl MC (2008) Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J 27:2929-2940.
    • (2008) EMBO J , vol.27 , pp. 2929-2940
    • Pena, V.1    Rozov, A.2    Fabrizio, P.3    Luhrmann, R.4    Wahl, M.C.5
  • 26
    • 55549121900 scopus 로고    scopus 로고
    • Structural elucidation of a PRP8 core domain from the heart of the spliceosome
    • Ritchie DB, et al. (2008) Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat Struct Mol Biol 15:1199-1205.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 1199-1205
    • Ritchie, D.B.1
  • 27
    • 52949131890 scopus 로고    scopus 로고
    • Crystal structure of the β-finger domain of Prp8 reveals analogy to ribosomal proteins
    • Yang K, Zhang L, Xu T, Heroux A, Zhao R (2008) Crystal structure of the β-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc Natl Acad Sci USA 105:13817-13822.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13817-13822
    • Yang, K.1    Zhang, L.2    Xu, T.3    Heroux, A.4    Zhao, R.5
  • 28
    • 33646004109 scopus 로고    scopus 로고
    • Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release
    • Nowotny M, Yang W (2006) Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. EMBO J 25:1924-1933.
    • (2006) EMBO J , vol.25 , pp. 1924-1933
    • Nowotny, M.1    Yang, W.2
  • 29
    • 1442360371 scopus 로고    scopus 로고
    • Three-dimensional structure of C complex spliceosomes by electron microscopy
    • Jurica MS, Sousa D, Moore MJ, Grigorieff N (2004) Three-dimensional structure of C complex spliceosomes by electron microscopy. Nat Struct Mol Biol 11:265-269.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 265-269
    • Jurica, M.S.1    Sousa, D.2    Moore, M.J.3    Grigorieff, N.4
  • 30
    • 68249149579 scopus 로고    scopus 로고
    • Exon, intron, and splice site locations in the spliceosomal B complex
    • 10.1038/emboj.2009.171
    • Wolf E, et al. (2009) Exon, intron, and splice site locations in the spliceosomal B complex. EMBO J, 10.1038/emboj.2009.171.
    • (2009) EMBO J
    • Wolf, E.1
  • 31
    • 60349110387 scopus 로고    scopus 로고
    • Structural mapping of spliceosomes by electron microscopy
    • Luhrmann R, Stark H (2009) Structural mapping of spliceosomes by electron microscopy. Curr Opin Struct Biol 19:96-102.
    • (2009) Curr Opin Struct Biol , vol.19 , pp. 96-102
    • Luhrmann, R.1    Stark, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.