Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release

EMBO Journal

Volumn 25, Issue 9, 2006, Pages 1924-1933

  Nowotny, Marcin ^a   Yang, Wei ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Ca2+; Mg2+; Mn2+; RNA DNA; Two metal ion catalysis

Indexed keywords

CALCIUM ION; DNA; MAGNESIUM ION; MANGANESE; METAL ION; RIBONUCLEASE H; RNA;

ARTICLE; CATALYSIS; CONCENTRATION (PARAMETERS); DISSOCIATION; DNA RNA HYBRIDIZATION; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; PRIORITY JOURNAL; REACTION ANALYSIS; RNA DEGRADATION;

BACILLUS; CATALYSIS; CATIONS, DIVALENT; CRYSTALLOGRAPHY; MAGNESIUM; MANGANESE; PROTEIN CONFORMATION; RIBONUCLEASE H, CALF THYMUS;

EID: 33646004109     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601076     Document Type: Article

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