메뉴 건너뛰기




Volumn 63, Issue 8, 2009, Pages 2164-2171

Low frequency of mutations with strongly deleterious but nonlethal fitness effects

Author keywords

Gene deletion; Growth rate; Protein complex; Saccharomyces cerevisiae

Indexed keywords

SACCHAROMYCES CEREVISIAE PROTEIN;

EID: 68149142374     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/j.1558-5646.2009.00713.x     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0346991749 scopus 로고    scopus 로고
    • Evolution in Saccharomyces cerevisiae: Identification of mutations increasing fitness in laboratory populations
    • and
    • Blanc, V., and J. Adams. 2003. Evolution in Saccharomyces cerevisiae: identification of mutations increasing fitness in laboratory populations. Genetics 165 : 975 983.
    • (2003) Genetics , vol.165 , pp. 975-983
    • Blanc, V.1    Adams, J.2
  • 3
    • 34250772513 scopus 로고    scopus 로고
    • Experimental estimate of the abundance and effects of nearly neutral mutations in the RNA virus phi 6
    • and
    • Burch, C. L., S. Guyader, D. Samarov, and H. Shen. 2007. Experimental estimate of the abundance and effects of nearly neutral mutations in the RNA virus phi 6. Genetics 176 : 467 476.
    • (2007) Genetics , vol.176 , pp. 467-476
    • Burch, C.L.1    Guyader, S.2    Samarov, D.3    Shen, H.4
  • 4
    • 0033543507 scopus 로고    scopus 로고
    • High frequency of cryptic deleterious mutations in Caenorhabditis elegans
    • and
    • Davies, E., A. Peters, and P. Keightley. 1999. High frequency of cryptic deleterious mutations in Caenorhabditis elegans. Science 285 : 1748 1751.
    • (1999) Science , vol.285 , pp. 1748-1751
    • Davies, E.1    Peters, A.2    Keightley, P.3
  • 5
    • 3943059570 scopus 로고    scopus 로고
    • High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome
    • and
    • Denver, D., K. Morris, M. Lynch, and W. Thomas. 2004. High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome. Nature 430 : 679 682.
    • (2004) Nature , vol.430 , pp. 679-682
    • Denver, D.1    Morris, K.2    Lynch, M.3    Thomas, W.4
  • 7
    • 0242659154 scopus 로고    scopus 로고
    • Bioinformatics analysis of experimentally determined protein complexes in the yeast Saccharomyces cerevisiae
    • and
    • Dezso, Z., Z. Oltvai, and A. Barabási. 2003. Bioinformatics analysis of experimentally determined protein complexes in the yeast Saccharomyces cerevisiae. Genome Res. 13 : 2450 2454.
    • (2003) Genome Res. , vol.13 , pp. 2450-2454
    • Dezso, Z.1    Oltvai, Z.2    Barabási, A.3
  • 8
    • 0008983173 scopus 로고    scopus 로고
    • Distribution of fitness effects caused by random insertion mutations in Escherichia coli
    • and
    • Elena, S. F., L. Ekunwe, N. Hajela, S. A. Oden, and R. E. Lenski. 1998. Distribution of fitness effects caused by random insertion mutations in Escherichia coli. Genetica 102-103 : 349 358.
    • (1998) Genetica , vol.102-103 , pp. 349-358
    • Elena, S.F.1    Ekunwe, L.2    Hajela, N.3    Oden, S.A.4    Lenski, R.E.5
  • 9
    • 34447546660 scopus 로고    scopus 로고
    • The distribution of fitness effects of new mutations
    • and
    • Eyre-Walker, A., and P. Keightley. 2007. The distribution of fitness effects of new mutations. Nat. Rev. Genet. 8 : 610 618.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 610-618
    • Eyre-Walker, A.1    Keightley, P.2
  • 10
    • 0036900082 scopus 로고    scopus 로고
    • Quantifying the slightly deleterious mutation model of molecular evolution
    • and
    • Eyre-Walker, A., P. Keightley, N. Smith, and D. Gaffney. 2002. Quantifying the slightly deleterious mutation model of molecular evolution. Mol. Biol. Evol. 19 : 2142 2149.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 2142-2149
    • Eyre-Walker, A.1    Keightley, P.2    Smith, N.3    Gaffney, D.4
  • 11
    • 7344234853 scopus 로고    scopus 로고
    • The mutation rate and the distribution of mutational effects of viability and fitness in Drosophila melanogaster
    • and
    • García-Dorado, A., J. Monedero, and C. López-Fanjul. 1998. The mutation rate and the distribution of mutational effects of viability and fitness in Drosophila melanogaster. Genetica 102-103 : 255 265.
    • (1998) Genetica , vol.102-103 , pp. 255-265
    • García-Dorado, A.1    Monedero, J.2    López-Fanjul, C.3
  • 14
    • 0347033256 scopus 로고    scopus 로고
    • Role of duplicate genes in genetic robustness against null mutations
    • DOI 10.1038/nature01198
    • Gu, Z., L. M. Steinmetz, X. Gu, C. Scharfe, R. W. Davis, and W. H. Li. 2003. Role of duplicate genes in genetic robustness against null mutations. Nature 421 : 63 66. (Pubitemid 36077084)
    • (2003) Nature , vol.421 , Issue.6918 , pp. 63-66
    • Gu, Z.1    Steinmetz, L.M.2    Gu, X.3    Scharfe, C.4    Davis, R.W.5    Li, W.-H.6
  • 17
    • 0033565762 scopus 로고    scopus 로고
    • Do essential genes evolve slowly?
    • and
    • Hurst, L. D., and N. G. Smith. 1999. Do essential genes evolve slowly? Curr. Biol. 9 : 747 750.
    • (1999) Curr. Biol. , vol.9 , pp. 747-750
    • Hurst, L.D.1    Smith, N.G.2
  • 18
    • 34047143174 scopus 로고    scopus 로고
    • Epistatic buffering of fitness loss in yeast double deletion strains
    • and
    • Jasnos, L., and R. Korona. 2007. Epistatic buffering of fitness loss in yeast double deletion strains. Nat. Genet. 39 : 550 554.
    • (2007) Nat. Genet. , vol.39 , pp. 550-554
    • Jasnos, L.1    Korona, R.2
  • 19
    • 27644578564 scopus 로고    scopus 로고
    • Resolution and repeatability of phenotypic assays by automated growth curve analysis in yeast and bacteria
    • and
    • Jasnos, L., P. Sliwa, and R. Korona. 2005. Resolution and repeatability of phenotypic assays by automated growth curve analysis in yeast and bacteria. Anal. Biochem. 344 : 138 140.
    • (2005) Anal. Biochem. , vol.344 , pp. 138-140
    • Jasnos, L.1    Sliwa, P.2    Korona, R.3
  • 20
    • 0019869334 scopus 로고
    • The molecular basis of dominance
    • and
    • Kacser, H., and J. Burns. 1981. The molecular basis of dominance. Genetics 97 : 639 666.
    • (1981) Genetics , vol.97 , pp. 639-666
    • Kacser, H.1    Burns, J.2
  • 22
    • 1942452749 scopus 로고    scopus 로고
    • Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae
    • and
    • Kellis, M., B. W. Birren, and E. S. Lander. 2004. Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae. Nature 428 : 617 624.
    • (2004) Nature , vol.428 , pp. 617-624
    • Kellis, M.1    Birren, B.W.2    Lander, E.S.3
  • 24
    • 33748649262 scopus 로고    scopus 로고
    • Inferring the distribution of mutational effects on fitness in Drosophila
    • and
    • Loewe, L., and B. Charlesworth. 2006. Inferring the distribution of mutational effects on fitness in Drosophila. Biol. Lett. 2 : 426 430.
    • (2006) Biol. Lett. , vol.2 , pp. 426-430
    • Loewe, L.1    Charlesworth, B.2
  • 26
    • 78651159254 scopus 로고
    • The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability
    • Mukai, T. 1964. The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability. Genetics 50 : 1 19.
    • (1964) Genetics , vol.50 , pp. 1-19
    • Mukai, T.1
  • 27
    • 0015405272 scopus 로고
    • Mutation rate and dominance of genes affecting viability in Drosophila melanogaster
    • and
    • Mukai, T., S. Chigusa, L. Mettler, and J. Crow. 1972. Mutation rate and dominance of genes affecting viability in Drosophila melanogaster. Genetics 72 : 335 355.
    • (1972) Genetics , vol.72 , pp. 335-355
    • Mukai, T.1    Chigusa, S.2    Mettler, L.3    Crow, J.4
  • 28
    • 0030071902 scopus 로고    scopus 로고
    • From DNA sequence to biological function
    • Oliver, S. 1996. From DNA sequence to biological function. Nature 379 : 597 600.
    • (1996) Nature , vol.379 , pp. 597-600
    • Oliver, S.1
  • 31
    • 2942565781 scopus 로고    scopus 로고
    • The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus
    • and
    • Sanjuán, R., A. Moya, and S. Elena. 2004. The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus. Proc. Natl. Acad. Sci. USA 101 : 8396 8401.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8396-8401
    • Sanjuán, R.1    Moya, A.2    Elena, S.3
  • 32
    • 28644443909 scopus 로고    scopus 로고
    • Deleterious mutation in related species of the plant genus Amsinckia with contrasting mating systems
    • Schoen, D. 2005. Deleterious mutation in related species of the plant genus Amsinckia with contrasting mating systems. Evolution 59 : 2370 2377.
    • (2005) Evolution , vol.59 , pp. 2370-2377
    • Schoen, D.1
  • 33
    • 29144454212 scopus 로고    scopus 로고
    • Loss of dispensable genes is not adaptive in yeast
    • and
    • Sliwa, P., and R. Korona. 2005. Loss of dispensable genes is not adaptive in yeast. Proc. Natl. Acad. Sci. USA 102 : 17670 17674.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17670-17674
    • Sliwa, P.1    Korona, R.2
  • 35
    • 33750959091 scopus 로고    scopus 로고
    • Higher intensity of purifying selection on >90% of the human genes revealed by the intrinsic replacement mutation rates
    • and
    • Subramanian, S., and S. Kumar. 2006. Higher intensity of purifying selection on >90% of the human genes revealed by the intrinsic replacement mutation rates. Mol. Biol. Evol. 23 : 2283 2287.
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 2283-2287
    • Subramanian, S.1    Kumar, S.2
  • 36
    • 0141504246 scopus 로고    scopus 로고
    • Small fitness effects and weak genetic interactions between deleterious mutations in heterozygous loci of the yeast Saccharomyces cerevisiae
    • and
    • Szafraniec, K., D. Wloch, P. Sliwa, R. Borts, and R. Korona. 2003. Small fitness effects and weak genetic interactions between deleterious mutations in heterozygous loci of the yeast Saccharomyces cerevisiae. Genet. Res. 82 : 19 31.
    • (2003) Genet. Res. , vol.82 , pp. 19-31
    • Szafraniec, K.1    Wloch, D.2    Sliwa, P.3    Borts, R.4    Korona, R.5
  • 37
    • 0031890960 scopus 로고    scopus 로고
    • Marginal fitness contributions of nonessential genes in yeast
    • and
    • Thatcher, J., J. Shaw, and W. Dickinson. 1998. Marginal fitness contributions of nonessential genes in yeast. Proc. Natl. Acad. Sci. USA 95 : 253 257.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 253-257
    • Thatcher, J.1    Shaw, J.2    Dickinson, W.3
  • 38
    • 0033229970 scopus 로고    scopus 로고
    • The economics of ribosome biosynthesis in yeast
    • Warner, J. 1999. The economics of ribosome biosynthesis in yeast. Trends Biochem. Sci. 24 : 437 440.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 437-440
    • Warner, J.1
  • 39
    • 0037438569 scopus 로고    scopus 로고
    • Automated screening in environmental arrays allows analysis of quantitative phenotypic profiles in Saccharomyces cerevisiae
    • and
    • Warringer, J., and A. Blomberg. 2003. Automated screening in environmental arrays allows analysis of quantitative phenotypic profiles in Saccharomyces cerevisiae. Yeast 20 : 53 67.
    • (2003) Yeast , vol.20 , pp. 53-67
    • Warringer, J.1    Blomberg, A.2
  • 40
    • 0347994900 scopus 로고    scopus 로고
    • High-resolution yeast phenomics resolves different physiological features in the saline response
    • and
    • Warringer, J., E. Ericson, L. Fernandez, O. Nerman, and A. Blomberg. 2003. High-resolution yeast phenomics resolves different physiological features in the saline response. Proc. Natl. Acad. Sci. USA 100 : 15724 15729.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15724-15729
    • Warringer, J.1    Ericson, E.2    Fernandez, L.3    Nerman, O.4    Blomberg, A.5
  • 41
    • 0034765995 scopus 로고    scopus 로고
    • Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae
    • and
    • Wloch, D., K. Szafraniec, R. Borts, and R. Korona. 2001. Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae. Genetics 159 : 441 452.
    • (2001) Genetics , vol.159 , pp. 441-452
    • Wloch, D.1    Szafraniec, K.2    Borts, R.3    Korona, R.4
  • 42
    • 27844543705 scopus 로고    scopus 로고
    • Human SNPs reveal no evidence of frequent positive selection
    • and
    • Zhang, L., and W. Li. 2005. Human SNPs reveal no evidence of frequent positive selection. Mol. Biol. Evol. 22 : 2504 2507.
    • (2005) Mol. Biol. Evol. , vol.22 , pp. 2504-2507
    • Zhang, L.1    Li, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.