Higher intensity of purifying selection on >90% of the human genes revealed by the intrinsic replacement mutation rates

Molecular Biology and Evolution

Volumn 23, Issue 12, 2006, Pages 2283-2287

  Subramanian, Sankar ^a,b,c   Kumar, Sudhir ^a,b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

Adaptive evolution; Comparative genomics; Mutation rate; Test of selection

Indexed keywords

DINUCLEOTIDE; MUTANT PROTEIN;

ARTICLE; CODON; CPG ISLAND; GENE MUTATION; GENE NUMBER; GENE SEQUENCE; GENETIC SELECTION; GENETIC VARIABILITY; GENOME; HUMAN; INTRON; MOLECULAR EVOLUTION; MUTATION RATE; NATURAL SELECTION;

ANIMALS; CPG ISLANDS; EVOLUTION, MOLECULAR; GENES; HUMANS; INTRONS; MODELS, GENETIC; MUTATION; PAN TROGLODYTES; SELECTION (GENETICS); VARIATION (GENETICS);

EID: 33750959091     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msl123     Document Type: Article

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