-
1
-
-
24644439190
-
Trends in the leading causes of death in the United States, 1970-2002
-
Jemal A, Ward E, Hao Y, Thun M. Trends in the leading causes of death in the United States, 1970-2002. J Am Med Assoc 2005;294:1255-9.
-
(2005)
J Am Med Assoc
, vol.294
, pp. 1255-1259
-
-
Jemal, A.1
Ward, E.2
Hao, Y.3
Thun, M.4
-
2
-
-
0035906213
-
Guidelines 2000 for colon and rectal cancer surgery
-
Nelson H, Petrelli N, Carlin A, Couture J, Fleshman J, Guillem J, et al. Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst 2001;93:583-96.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 583-596
-
-
Nelson, H.1
Petrelli, N.2
Carlin, A.3
Couture, J.4
Fleshman, J.5
Guillem, J.6
-
4
-
-
0032939619
-
Rho GTPases are over-expressed in human tumors
-
Fritz G, Just I, Kaina B. Rho GTPases are over-expressed in human tumors. Int J Cancer 1999;81:682-7.
-
(1999)
Int J Cancer
, vol.81
, pp. 682-687
-
-
Fritz, G.1
Just, I.2
Kaina, B.3
-
5
-
-
0032497699
-
Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway
-
Esteve P, Embade N, Perona R, Jiménez B, del Peso L, León J, et al. Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway. Oncogene 1998;17:1855-69.
-
(1998)
Oncogene
, vol.17
, pp. 1855-1869
-
-
Esteve, P.1
Embade, N.2
Perona, R.3
Jiménez, B.4
del Peso, L.5
León, J.6
-
6
-
-
33750594388
-
Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma
-
Bellovin DI, Simpson KJ, Danilov T, Maynard E, Rimm DL, Oettgen P, et al. Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma. Oncogene 2006;25:6959-67.
-
(2006)
Oncogene
, vol.25
, pp. 6959-6967
-
-
Bellovin, D.I.1
Simpson, K.J.2
Danilov, T.3
Maynard, E.4
Rimm, D.L.5
Oettgen, P.6
-
7
-
-
38649118554
-
The activity of RhoA is correlated with lymph node metastasis in human colorectal cancer
-
Takami Y, Higashi M, Kumagai S, Kuo PC, Kawana H, Koda K, et al. The activity of RhoA is correlated with lymph node metastasis in human colorectal cancer. Dig Dis Sci 2008;53:467-73.
-
(2008)
Dig Dis Sci
, vol.53
, pp. 467-473
-
-
Takami, Y.1
Higashi, M.2
Kumagai, S.3
Kuo, P.C.4
Kawana, H.5
Koda, K.6
-
8
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001;25:402-8.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
10
-
-
0942268723
-
Rho GTPases have diverse effects on the organization of the actin filament system
-
Aspenstrom P, Fransson A, Saras J. Rho GTPases have diverse effects on the organization of the actin filament system. Biochem J 2004;377:327-37.
-
(2004)
Biochem J
, vol.377
, pp. 327-337
-
-
Aspenstrom, P.1
Fransson, A.2
Saras, J.3
-
11
-
-
0028863142
-
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
-
Leung T, Manser E, Tan L, Lim L. A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem 1995;270:29051-4.
-
(1995)
J Biol Chem
, vol.270
, pp. 29051-29054
-
-
Leung, T.1
Manser, E.2
Tan, L.3
Lim, L.4
-
12
-
-
9244257348
-
Rho-associated kinase, a novel serine/ threonine kinase, as a putative target for small GTP binding protein Rho
-
Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, et al. Rho-associated kinase, a novel serine/ threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 1996;15:2208-16.
-
(1996)
EMBO J
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuku, M.5
Ito, M.6
-
13
-
-
33749347923
-
Mobility and invasiveness of metastatic esophageal cancer are potentiated by shear stress in a ROCK- and Ras-depend- ent manner
-
Lawler K, Foran E, O'Sullivan G, Long A, Kenny D. Mobility and invasiveness of metastatic esophageal cancer are potentiated by shear stress in a ROCK- and Ras-depend- ent manner. Am J Physiol Cell Physiol 2006;291: C668-77.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Lawler, K.1
Foran, E.2
O'Sullivan, G.3
Long, A.4
Kenny, D.5
-
14
-
-
0033864069
-
Y-27632, an inhibitor of Rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase
-
Imamura F, Mukai M, Ayaki M, Akedo H. Y-27632, an inhibitor of Rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase. Jpn J Cancer Res 2000;91:811-6.
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 811-816
-
-
Imamura, F.1
Mukai, M.2
Ayaki, M.3
Akedo, H.4
-
15
-
-
0034708373
-
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells
-
Somlyo AV, Bradshaw D, Ramos S, Murphy C, Myers CE, Somlyo AP. Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells. Biochem Biophys Res Commun 2000;269:652-9.
-
(2000)
Biochem Biophys Res Commun
, vol.269
, pp. 652-659
-
-
Somlyo, A.V.1
Bradshaw, D.2
Ramos, S.3
Murphy, C.4
Myers, C.E.5
Somlyo, A.P.6
-
16
-
-
9944251987
-
Rho GTPases in human cancer: An unresolved link to upstream and downstream transcriptional regulation
-
Benitah SA, Valeron PF, van Aelst L, Marshall CJ, Lacal JC. Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochem Biophys Acta 2004;1705:121-32.
-
(2004)
Biochem Biophys Acta
, vol.1705
, pp. 121-132
-
-
Benitah, S.A.1
Valeron, P.F.2
van Aelst, L.3
Marshall, C.J.4
Lacal, J.C.5
-
17
-
-
33645516549
-
PRL tyrosine phospha- tases regulate rho family GTPases to promote invasion and motility
-
Fiordalisi JJ, Keller PJ, Cox AD. PRL tyrosine phospha- tases regulate rho family GTPases to promote invasion and motility. Cancer Res 2006;66:3153-61.
-
(2006)
Cancer Res
, vol.66
, pp. 3153-3161
-
-
Fiordalisi, J.J.1
Keller, P.J.2
Cox, A.D.3
-
18
-
-
0036158675
-
3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis
-
Kusama T, Mukai M, Iwasaki T, Tatsuta M, Matsumoto Y, Akedo H, et al. 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. Gastroenterology 2002; 122:308-17.
-
(2002)
Gastroenterology
, vol.122
, pp. 308-317
-
-
Kusama, T.1
Mukai, M.2
Iwasaki, T.3
Tatsuta, M.4
Matsumoto, Y.5
Akedo, H.6
-
19
-
-
19944432271
-
Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo
-
Pille JY, Denoyelle C, Varet J, Bertrand JR, Soria J, Opo- lon P, et al. Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo. Mol Ther 2005;11: 267-74.
-
(2005)
Mol Ther
, vol.11
, pp. 267-274
-
-
Pille, J.Y.1
Denoyelle, C.2
Varet, J.3
Bertrand, J.R.4
Soria, J.5
Opo- lon, P.6
-
20
-
-
34247468418
-
IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway
-
Lin MT, Lin BR, Chang CC, Chu CY, Su HJ, Chen ST, et al. IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway. Int J Cancer 2007;120:2600-8.
-
(2007)
Int J Cancer
, vol.120
, pp. 2600-2608
-
-
Lin, M.T.1
Lin, B.R.2
Chang, C.C.3
Chu, C.Y.4
Su, H.J.5
Chen, S.T.6
-
21
-
-
0035865137
-
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
-
Sahai E, Olson MF, Marshall CJ. Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility. EMBO J 2001; 20:755-66.
-
(2001)
EMBO J
, vol.20
, pp. 755-766
-
-
Sahai, E.1
Olson, M.F.2
Marshall, C.J.3
-
22
-
-
1042278714
-
A definitive role of RhoC in metastasis of ortho- topic lung cancer in mice
-
Ikoma T, Takahashi T, Nagano S, Li YM, Ohon Y, Ando K, et al. A definitive role of RhoC in metastasis of ortho- topic lung cancer in mice. Clin Cancer Res 2004;10: 1192-200.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1192-1200
-
-
Ikoma, T.1
Takahashi, T.2
Nagano, S.3
Li, Y.M.4
Ohon, Y.5
Ando, K.6
-
23
-
-
3042739357
-
Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis
-
Wang W, Yang LY, Huang GW, Lu WQ, Yang ZL, Yang JQ, et al. Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis. Br J Cancer 2004;90:2349-55.
-
(2004)
Br J Cancer
, vol.90
, pp. 2349-2355
-
-
Wang, W.1
Yang, L.Y.2
Huang, G.W.3
Lu, W.Q.4
Yang, Z.L.5
Yang, J.Q.6
-
24
-
-
0035944830
-
GTPases as early markers for tumour progression
-
Keely PJ. Rho GTPases as early markers for tumour progression. Lancet 2001;358:1744-5.
-
(2001)
Lancet
, vol.358
, pp. 1744-1745
-
-
Rho, K.P.J.1
-
25
-
-
0034601487
-
Genomic analysis of metastasis reveals an essential role for RhoC
-
Clark EA, Golub TR, Lander ES, Hynes RO. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 2000;406:532-5.
-
(2000)
Nature
, vol.406
, pp. 532-535
-
-
Clark, E.A.1
Golub, T.R.2
Lander, E.S.3
Hynes, R.O.4
-
26
-
-
41549155644
-
Correlation of expression of RhoC with invasiveness of prostate cancer cell line PC-3M in vitro
-
Yuan Z, Su J, You JF, Wang JL, Cui XL, Zheng J. Correlation of expression of RhoC with invasiveness of prostate cancer cell line PC-3M in vitro. Zhonghua Yi Xue Za Zhi 2008;88:51-5.
-
(2008)
Zhonghua Yi Xue Za Zhi
, vol.88
, pp. 51-55
-
-
Yuan, Z.1
Su, J.2
You, J.F.3
Wang, J.L.4
Cui, X.L.5
Zheng, J.6
-
27
-
-
67849115457
-
Effect of retrovirus- mediated RhoC-siRNA on biological behaviors of human high-metastatic liver cancer cells
-
Tang NH, Wang XQ, Li XJ, Chen YL. Effect of retrovirus- mediated RhoC-siRNA on biological behaviors of human high-metastatic liver cancer cells. Chinese J Exp Surg 2006;23:1299-301.
-
(2006)
Chinese J Exp Surg
, vol.23
, pp. 1299-1301
-
-
Tang, N.H.1
Wang, X.Q.2
Li, X.J.3
Chen, Y.L.4
-
28
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29:e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
29
-
-
0036581160
-
Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
-
Pfaffl MW, Horgan GW, Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 2002;30:e36.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Pfaffl, M.W.1
Horgan, G.W.2
Dempfle, L.3
-
30
-
-
34547427442
-
RhoA and RhoC-siRNA inhibit the proliferation and inva- siveness activity of human gastric carcinoma by Rho/ PI3K/Akt pathway
-
Sun HW, Tong SL, He J, Wang Q, Zou L, Ma SJ, et al. RhoA and RhoC-siRNA inhibit the proliferation and inva- siveness activity of human gastric carcinoma by Rho/ PI3K/Akt pathway. World J Gastroenterol 2007;13:3517- 22.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 3517-3522
-
-
Sun, H.W.1
Tong, S.L.2
He, J.3
Wang, Q.4
Zou, L.5
Ma, S.J.6
-
31
-
-
36348997060
-
Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma
-
Faried A, Faried LS, Usman N, Kato H, Kuwano H. Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma. Ann Surg Oncol 2007;14:3593-601.
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 3593-3601
-
-
Faried, A.1
Faried, L.S.2
Usman, N.3
Kato, H.4
Kuwano, H.5
-
32
-
-
34948824840
-
Involvement of RhoA in progression of human hepato- cellular carcinoma
-
Wang D, Dou K, Xiang H, Song Z, Zhao Q, Chen Y, et al. Involvement of RhoA in progression of human hepato- cellular carcinoma. J Gastroenterol Hepatol 2007;22: 1916-20.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 1916-1920
-
-
Wang, D.1
Dou, K.2
Xiang, H.3
Song, Z.4
Zhao, Q.5
Chen, Y.6
-
33
-
-
0038679226
-
Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
-
Horiuchi A, Imai T, Wang C, Ohira S, Feng Y, Nikaido T, et al. Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma. Lab Invest 2003;83:861-70.
-
(2003)
Lab Invest
, vol.83
, pp. 861-870
-
-
Horiuchi, A.1
Imai, T.2
Wang, C.3
Ohira, S.4
Feng, Y.5
Nikaido, T.6
-
34
-
-
0242694457
-
Higher expression of RhoC is related to invasiveness in non-small cell lung carcinoma
-
Shikada Y, Yoshino I, Okamoto T, Fukuyama S, Kameya- ma T, Maehara Y. Higher expression of RhoC is related to invasiveness in non-small cell lung carcinoma. Clin Cancer Res 2003;9:5282-6.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5282-5286
-
-
Shikada, Y.1
Yoshino, I.2
Okamoto, T.3
Fukuyama, S.4
Kameya- ma, T.5
Maehara, Y.6
|