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Volumn 4, Issue 7, 2009, Pages 1075-1085

Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy) ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters

(6) Kharkar, Prashant S a,d Batman, Angela M b Zhen, Juan c Beardsley, Patrick M b Reith, Maarten E A c Dutta, Aloke K a

a WAYNE STATE UNIVERSITY (United States)

b VIRGINIA COMMONWEALTH UNIVERSITY (United States)

c NEW YORK UNIVERSITY (United States)

d Piramal Enterprises Limited (India)

Author keywords

Cocaine; Dopamine; Monoamine transporters; Structure activity relationships

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 4 (2 (BENZHYDRYLOXY)ETHYL) 1 (2 (4 FLUOROPHENYL) 2 HYDROXYETHYL)PIPERIDIN 3 OL; 4 (2 (BENZHYDRYLOXY)ETHYL) 1 (2 HYDROXY 2 PHENYLETHYL)PIPERIDIN 3 OL; 4 VINYLPYRIDINE; COCAINE; DOPAMINE TRANSPORTER; MONOAMINE; NORADRENALIN TRANSPORTER; PIPERIDINE DERIVATIVE; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; VANOXERINE;

AMINE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOISOMERISM;

ANIMALS; BENZHYDRYL COMPOUNDS; BRAIN; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; MICE; MOTOR ACTIVITY; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PIPERIDINES; RATS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STEREOISOMERISM;

EID: 67749137583 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200900085 Document Type: Article

Times cited : (13)

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