-
1
-
-
0028787766
-
Bupropion: a review of its mechanism of antidepressant activity
-
Ascher J.A., Cole J.O., Colin J.N., Feighner J.P., Ferris R.M., Fibiger H.C., Golden R.N., Martin P., Potter W.Z., and Richelson E. Bupropion: a review of its mechanism of antidepressant activity. J. Clin. Psychiatry 56 (1995) 395-401
-
(1995)
J. Clin. Psychiatry
, vol.56
, pp. 395-401
-
-
Ascher, J.A.1
Cole, J.O.2
Colin, J.N.3
Feighner, J.P.4
Ferris, R.M.5
Fibiger, H.C.6
Golden, R.N.7
Martin, P.8
Potter, W.Z.9
Richelson, E.10
-
2
-
-
47549110809
-
-
Brunton L.L., Lazo J.S., and Parker K.L. (Eds), McGraw-Hill, New York
-
Baldessarini R.J. In: Brunton L.L., Lazo J.S., and Parker K.L. (Eds). Goodman & Gilman's the Pharmacological Basis of Therapeutics. 11th ed. (2006), McGraw-Hill, New York 443
-
(2006)
Goodman & Gilman's the Pharmacological Basis of Therapeutics. 11th ed.
, pp. 443
-
-
Baldessarini, R.J.1
-
3
-
-
0027368993
-
Fluoxetine compared with imipramine in the treatment of inpatient depression. A multicenter trial
-
Beasley Jr. C.M., Holman S.L., and Potvin J.H. Fluoxetine compared with imipramine in the treatment of inpatient depression. A multicenter trial. Ann. Clin. Psychiatry 5 (1993) 199-207
-
(1993)
Ann. Clin. Psychiatry
, vol.5
, pp. 199-207
-
-
Beasley Jr., C.M.1
Holman, S.L.2
Potvin, J.H.3
-
4
-
-
0037338273
-
The pharmacology of putative early-onset antidepressant strategies
-
Blier P. The pharmacology of putative early-onset antidepressant strategies. Eur. Neuropsychopharmacol. 13 (2003) 57-66
-
(2003)
Eur. Neuropsychopharmacol.
, vol.13
, pp. 57-66
-
-
Blier, P.1
-
5
-
-
0031690668
-
New approaches to rapid onset antidepressants
-
Briner K., and Dodel R.C. New approaches to rapid onset antidepressants. Curr. Pharm. Des. 4 (1998) 291-302
-
(1998)
Curr. Pharm. Des.
, vol.4
, pp. 291-302
-
-
Briner, K.1
Dodel, R.C.2
-
6
-
-
0036787072
-
The role of noradrenaline and selective noradrenaline reuptake inhibition in depression
-
Brunello N., Mendlewicz J., Kasper S., Leonard B., Montgomery S., Nelson J., Paykel E., Versiani M., and Racagni G. The role of noradrenaline and selective noradrenaline reuptake inhibition in depression. Eur. Neuropsychopharmacol. 12 (2002) 461-475
-
(2002)
Eur. Neuropsychopharmacol.
, vol.12
, pp. 461-475
-
-
Brunello, N.1
Mendlewicz, J.2
Kasper, S.3
Leonard, B.4
Montgomery, S.5
Nelson, J.6
Paykel, E.7
Versiani, M.8
Racagni, G.9
-
7
-
-
0038102798
-
Noradrenaline in mood and anxiety disorders: basic and clinical studies
-
Brunello N., Blier P., Judd L.L., Mendlewicz J., Nelson C.J., Souery D., Zohar J., and Racagni G. Noradrenaline in mood and anxiety disorders: basic and clinical studies. Int. Clin. Psychopharmacol. 18 (2003) 191-202
-
(2003)
Int. Clin. Psychopharmacol.
, vol.18
, pp. 191-202
-
-
Brunello, N.1
Blier, P.2
Judd, L.L.3
Mendlewicz, J.4
Nelson, C.J.5
Souery, D.6
Zohar, J.7
Racagni, G.8
-
8
-
-
0015861774
-
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
-
Cheng Y., and Prusoff W.H. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 22 (1973) 3099-3108
-
(1973)
Biochem. Pharmacol.
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.1
Prusoff, W.H.2
-
9
-
-
0027263837
-
Side-effects of antidepressants
-
Suppl
-
Cookson J. Side-effects of antidepressants. Br. J. Psychiatry (1993) 20-24 Suppl
-
(1993)
Br. J. Psychiatry
, pp. 20-24
-
-
Cookson, J.1
-
10
-
-
0034007549
-
Comparison of pramipexole, fluoxetine, and placebo in patients with major depression
-
Corrigan M.H., Denahan A.Q., Wright C.E., Ragual R.J., and Evans D.L. Comparison of pramipexole, fluoxetine, and placebo in patients with major depression. Depress. Anxiety 11 (2000) 58-65
-
(2000)
Depress. Anxiety
, vol.11
, pp. 58-65
-
-
Corrigan, M.H.1
Denahan, A.Q.2
Wright, C.E.3
Ragual, R.J.4
Evans, D.L.5
-
11
-
-
0036570222
-
Assessing antidepressant activity in rodents: recent developments and future needs
-
Cryan J.F., Markou A., and Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol. Sci. 23 (2002) 238-245
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 238-245
-
-
Cryan, J.F.1
Markou, A.2
Lucki, I.3
-
12
-
-
2542602316
-
Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors
-
Cryan J.F., O'Leary O.F., Jin S.H., Friedland J.C., Ouyang M., Hirsch B.R., Page M.E., Dalvi A., Thomas S.A., and Lucki I. Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 8186-8191
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 8186-8191
-
-
Cryan, J.F.1
O'Leary, O.F.2
Jin, S.H.3
Friedland, J.C.4
Ouyang, M.5
Hirsch, B.R.6
Page, M.E.7
Dalvi, A.8
Thomas, S.A.9
Lucki, I.10
-
13
-
-
0034730472
-
The role of dopamine in the mechanism of action of antidepressant drugs
-
D'Aquila P.S., Collu M., Gessa G.L., and Serra G. The role of dopamine in the mechanism of action of antidepressant drugs. Eur. J. Pharmacol. 405 (2000) 365-373
-
(2000)
Eur. J. Pharmacol.
, vol.405
, pp. 365-373
-
-
D'Aquila, P.S.1
Collu, M.2
Gessa, G.L.3
Serra, G.4
-
14
-
-
0037228029
-
The neural substrates of affective processing in depressed patients treated with venlafaxine
-
Davidson R.J., Irwin W., Anderle M.J., and Kalin N.H. The neural substrates of affective processing in depressed patients treated with venlafaxine. Am. J. Psychiatry 160 (2003) 64-75
-
(2003)
Am. J. Psychiatry
, vol.160
, pp. 64-75
-
-
Davidson, R.J.1
Irwin, W.2
Anderle, M.J.3
Kalin, N.H.4
-
15
-
-
0028037784
-
Suicidality in patients with pure and depressive mania
-
Dilsaver S.C., Chen Y.W., Swann A.C., Shoaib A.M., and Krajewski K.J. Suicidality in patients with pure and depressive mania. Am. J. Psychiatry 151 (1994) 1312-1315
-
(1994)
Am. J. Psychiatry
, vol.151
, pp. 1312-1315
-
-
Dilsaver, S.C.1
Chen, Y.W.2
Swann, A.C.3
Shoaib, A.M.4
Krajewski, K.J.5
-
16
-
-
0242408732
-
Dopamine transporter as target for drug development of cocaine dependence medications
-
Dutta A.K., Zhang S., Kolhatkar R., and Reith M.E. Dopamine transporter as target for drug development of cocaine dependence medications. Eur. J. Pharmacol. 479 (2003) 93-106
-
(2003)
Eur. J. Pharmacol.
, vol.479
, pp. 93-106
-
-
Dutta, A.K.1
Zhang, S.2
Kolhatkar, R.3
Reith, M.E.4
-
17
-
-
0032927199
-
Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type
-
Eshleman A.J., Carmolli M., Cumbay M., Martens C.R., Neve K.A., and Janowsky A. Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type. J. Pharmacol. Exp. Ther. 289 (1999) 877-885
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 877-885
-
-
Eshleman, A.J.1
Carmolli, M.2
Cumbay, M.3
Martens, C.R.4
Neve, K.A.5
Janowsky, A.6
-
18
-
-
0031732861
-
Selective serotonin reuptake inhibitors in the treatment of affective disorders-III. Tolerability, safety and pharmacoeconomics
-
Goldstein B.J., and Goodnick P.J. Selective serotonin reuptake inhibitors in the treatment of affective disorders-III. Tolerability, safety and pharmacoeconomics. J. Psychopharmacol. 12 (1998) S55-87
-
(1998)
J. Psychopharmacol.
, vol.12
-
-
Goldstein, B.J.1
Goodnick, P.J.2
-
19
-
-
0030590656
-
Plasma dopamine and norepinephrine correlations with psychomotor retardation, anxiety, and depression in non-psychotic depressed patients: a pilot study
-
Hamner M.B., and Diamond B.I. Plasma dopamine and norepinephrine correlations with psychomotor retardation, anxiety, and depression in non-psychotic depressed patients: a pilot study. Psychiatry. Res. 64 (1996) 209-211
-
(1996)
Psychiatry. Res.
, vol.64
, pp. 209-211
-
-
Hamner, M.B.1
Diamond, B.I.2
-
20
-
-
0034130015
-
Noradrenaline and serotonin reuptake inhibition as clinical principles: a review of antidepressant efficacy
-
Humble M. Noradrenaline and serotonin reuptake inhibition as clinical principles: a review of antidepressant efficacy. Acta Psychiatr. Scand. Suppl. 402 (2000) 28-36
-
(2000)
Acta Psychiatr. Scand. Suppl.
, vol.402
, pp. 28-36
-
-
Humble, M.1
-
21
-
-
0033938105
-
Neurotransmitter transporters: fruitful targets for CNS drug discovery
-
Iversen L. Neurotransmitter transporters: fruitful targets for CNS drug discovery. Mol. Psychiatry 5 (2000) 357-362
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 357-362
-
-
Iversen, L.1
-
22
-
-
0036791096
-
Dopaminergic abnormalities in amygdaloid nuclei in major depression: a postmortem study
-
Klimek V., Schenck J.E., Han H., Stockmeier C.A., and Ordway G.A. Dopaminergic abnormalities in amygdaloid nuclei in major depression: a postmortem study. Biol. Psychiatry 52 (2002) 740-748
-
(2002)
Biol. Psychiatry
, vol.52
, pp. 740-748
-
-
Klimek, V.1
Schenck, J.E.2
Han, H.3
Stockmeier, C.A.4
Ordway, G.A.5
-
23
-
-
0142059144
-
Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats
-
Koch S., Hemrick-Luecke S.K., Thompson L.K., Evans D.C., Threlkeld P.G., Nelson D.L., Perry K.W., and Bymaster F.P. Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats. Neuropharmacology 45 (2003) 935-944
-
(2003)
Neuropharmacology
, vol.45
, pp. 935-944
-
-
Koch, S.1
Hemrick-Luecke, S.K.2
Thompson, L.K.3
Evans, D.C.4
Threlkeld, P.G.5
Nelson, D.L.6
Perry, K.W.7
Bymaster, F.P.8
-
24
-
-
0031789272
-
The global burden of disease, 1990-2020
-
Lopez A.D., and Murray C.C. The global burden of disease, 1990-2020. Nat. Med. 4 (1998) 1241-1243
-
(1998)
Nat. Med.
, vol.4
, pp. 1241-1243
-
-
Lopez, A.D.1
Murray, C.C.2
-
25
-
-
0034203663
-
Strategies for managing depression refractory to selective serotonin reuptake inhibitor treatment: a survey of clinicians
-
Mischoulon D., Nierenberg A.A., Kizilbash L., Rosenbaum J.F., and Fava M. Strategies for managing depression refractory to selective serotonin reuptake inhibitor treatment: a survey of clinicians. Can. J. Psychiatry 45 (2000) 476-481
-
(2000)
Can. J. Psychiatry
, vol.45
, pp. 476-481
-
-
Mischoulon, D.1
Nierenberg, A.A.2
Kizilbash, L.3
Rosenbaum, J.F.4
Fava, M.5
-
26
-
-
0036018492
-
Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction
-
Montgomery S.A., Baldwin D.S., and Riley A. Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction. J. Affect. Disord. 69 (2002) 119-140
-
(2002)
J. Affect. Disord.
, vol.69
, pp. 119-140
-
-
Montgomery, S.A.1
Baldwin, D.S.2
Riley, A.3
-
27
-
-
0032192374
-
Psychopharmacology of affective disorders in the 21st century
-
Nemeroff C.B. Psychopharmacology of affective disorders in the 21st century. Biol. Psychiatry 44 (1998) 517-525
-
(1998)
Biol. Psychiatry
, vol.44
, pp. 517-525
-
-
Nemeroff, C.B.1
-
28
-
-
0025365966
-
Treatment-resistant depression: definition and treatment approaches
-
discussion
-
Nierenberg A.A., and Amsterdam J.D. Treatment-resistant depression: definition and treatment approaches. J. Clin. Psychiatry 51 Suppl 39-47 (1990) 48-50 discussion
-
(1990)
J. Clin. Psychiatry
, vol.51
, Issue.SUPPL. 39-47
, pp. 48-50
-
-
Nierenberg, A.A.1
Amsterdam, J.D.2
-
29
-
-
1942452347
-
Placebo-controlled continuation treatment with mirtazapine: acute pattern of response predicts relapse
-
Nierenberg A.A., Quitkin F.M., Kremer C., Keller M.B., and Thase M.E. Placebo-controlled continuation treatment with mirtazapine: acute pattern of response predicts relapse. Neuropsychopharmacology 29 (2004) 1012-1018
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1012-1018
-
-
Nierenberg, A.A.1
Quitkin, F.M.2
Kremer, C.3
Keller, M.B.4
Thase, M.E.5
-
30
-
-
0031456987
-
Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites
-
Owens M.J., Morgan W.N., Plott S.J., and Nemeroff C.B. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J. Pharmacol. Exp. Ther. 283 (1997) 1305-1322
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.283
, pp. 1305-1322
-
-
Owens, M.J.1
Morgan, W.N.2
Plott, S.J.3
Nemeroff, C.B.4
-
31
-
-
0030013434
-
Antidepressants and cognitive impairment in the elderly
-
Oxman T.E. Antidepressants and cognitive impairment in the elderly. J. Clin. Psychiatry. 57 Suppl 5 (1996) 38-44
-
(1996)
J. Clin. Psychiatry.
, vol.57
, Issue.SUPPL. 5
, pp. 38-44
-
-
Oxman, T.E.1
-
32
-
-
33745676287
-
Dopaminergic-based pharmacotherapies for depression
-
Papakostas G.I. Dopaminergic-based pharmacotherapies for depression. Eur. Neuropsychopharmacol. 16 (2006) 391-402
-
(2006)
Eur. Neuropsychopharmacol.
, vol.16
, pp. 391-402
-
-
Papakostas, G.I.1
-
33
-
-
0027399143
-
Third-generation antidepressants
-
Pinder R.M., and Wieringa J.H. Third-generation antidepressants. Med. Res. Rev. 13 (1993) 259-325
-
(1993)
Med. Res. Rev.
, vol.13
, pp. 259-325
-
-
Pinder, R.M.1
Wieringa, J.H.2
-
34
-
-
34247575765
-
Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677
-
Popik P., Krawczyk M., Golembiowska K., Nowak G., Janowsky A., Skolnick P., Lippa A., and Basile A.S. Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677. Cell. Mol. Neurobiol. 26 (2006) 857-873
-
(2006)
Cell. Mol. Neurobiol.
, vol.26
, pp. 857-873
-
-
Popik, P.1
Krawczyk, M.2
Golembiowska, K.3
Nowak, G.4
Janowsky, A.5
Skolnick, P.6
Lippa, A.7
Basile, A.S.8
-
35
-
-
0017618768
-
Depression: a new animal model sensitive to antidepressant treatments
-
Porsolt R.D., Le Pichon M., and Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 266 (1977) 730-732
-
(1977)
Nature
, vol.266
, pp. 730-732
-
-
Porsolt, R.D.1
Le Pichon, M.2
Jalfre, M.3
-
36
-
-
0022397753
-
Plasma norepinephrine level in affective disorders. Relationship to melancholia
-
Roy A., Pickar D., Linnoila M., and Potter W.Z. Plasma norepinephrine level in affective disorders. Relationship to melancholia. Arch. Gen. Psychiatry 42 (1985) 1181-1185
-
(1985)
Arch. Gen. Psychiatry
, vol.42
, pp. 1181-1185
-
-
Roy, A.1
Pickar, D.2
Linnoila, M.3
Potter, W.Z.4
-
37
-
-
0031837488
-
The serotonin transporter: a primary target for antidepressant drugs
-
Schloss P., and Williams D.C. The serotonin transporter: a primary target for antidepressant drugs. J. Psychopharmacol. 12 (1998) 115-121
-
(1998)
J. Psychopharmacol.
, vol.12
, pp. 115-121
-
-
Schloss, P.1
Williams, D.C.2
-
38
-
-
0023248852
-
Preclinical evaluation of McN-5707 as a potential antidepressant
-
Shank R.P., Gardocki J.F., Schneider C.R., Vaught J.L., Setler P.E., Maryanoff B.E., and McComsey D.F. Preclinical evaluation of McN-5707 as a potential antidepressant. J. Pharmacol. Exp. Ther. 242 (1987) 74-84
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.242
, pp. 74-84
-
-
Shank, R.P.1
Gardocki, J.F.2
Schneider, C.R.3
Vaught, J.L.4
Setler, P.E.5
Maryanoff, B.E.6
McComsey, D.F.7
-
39
-
-
0024241568
-
McN-5652: a highly potent inhibitor of serotonin uptake
-
Shank R.P., Vaught J.L., Pelley K.A., Setler P.E., McComsey D.F., and Maryanoff B.E. McN-5652: a highly potent inhibitor of serotonin uptake. J. Pharmacol. Exp. Ther. 247 (1988) 1032-1038
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.247
, pp. 1032-1038
-
-
Shank, R.P.1
Vaught, J.L.2
Pelley, K.A.3
Setler, P.E.4
McComsey, D.F.5
Maryanoff, B.E.6
-
40
-
-
33845804288
-
Antidepressant-like effects of novel triple reuptake inhibitors, PRC025 and PRC050
-
Shaw A.M., Boules M., Zhang Y., Williams K., Robinson J., Carlier P.R., and Richelson E. Antidepressant-like effects of novel triple reuptake inhibitors, PRC025 and PRC050. Eur. J. Pharmacol. 555 (2007) 30-36
-
(2007)
Eur. J. Pharmacol.
, vol.555
, pp. 30-36
-
-
Shaw, A.M.1
Boules, M.2
Zhang, Y.3
Williams, K.4
Robinson, J.5
Carlier, P.R.6
Richelson, E.7
-
41
-
-
12244291291
-
Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor
-
Skolnick P., Popik P., Janowsky A., Beer B., and Lippa A.S. Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor. Eur. J. Pharmacol. 461 (2003) 99-104
-
(2003)
Eur. J. Pharmacol.
, vol.461
, pp. 99-104
-
-
Skolnick, P.1
Popik, P.2
Janowsky, A.3
Beer, B.4
Lippa, A.S.5
-
42
-
-
0141961847
-
"Broad spectrum" antidepressants: is more better for the treatment of depression?
-
Skolnick P., Popik P., Janowsky A., Beer B., and Lippa A.S. "Broad spectrum" antidepressants: is more better for the treatment of depression?. Life Sci. 73 (2003) 3175-3179
-
(2003)
Life Sci.
, vol.73
, pp. 3175-3179
-
-
Skolnick, P.1
Popik, P.2
Janowsky, A.3
Beer, B.4
Lippa, A.S.5
-
43
-
-
0033862666
-
Pramipexole augmentation in the treatment of unipolar and bipolar depression: a retrospective chart review
-
Sporn J., Ghaemi S.N., Sambur M.R., Rankin M.A., Recht J., Sachs G.S., Rosenbaum J.F., and Fava M. Pramipexole augmentation in the treatment of unipolar and bipolar depression: a retrospective chart review. Ann. Clin. Psychiatry 12 (2000) 137-140
-
(2000)
Ann. Clin. Psychiatry
, vol.12
, pp. 137-140
-
-
Sporn, J.1
Ghaemi, S.N.2
Sambur, M.R.3
Rankin, M.A.4
Recht, J.5
Sachs, G.S.6
Rosenbaum, J.F.7
Fava, M.8
-
44
-
-
0021990491
-
The tail suspension test: a new method for screening antidepressants in mice
-
Steru L., Chermat R., Thierry B., and Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology (Berl.) 85 (1985) 367-370
-
(1985)
Psychopharmacology (Berl.)
, vol.85
, pp. 367-370
-
-
Steru, L.1
Chermat, R.2
Thierry, B.3
Simon, P.4
-
46
-
-
0031565115
-
Pharmacological profile of antidepressants and related compounds at human monoamine transporters
-
Tatsumi M., Groshan K., Blakely R.D., and Richelson E. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur. J. Pharmacol. 340 (1997) 249-258
-
(1997)
Eur. J. Pharmacol.
, vol.340
, pp. 249-258
-
-
Tatsumi, M.1
Groshan, K.2
Blakely, R.D.3
Richelson, E.4
-
47
-
-
1642441739
-
Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity
-
Vaishnavi S.N., Nemeroff C.B., Plott S.J., Rao S.G., Kranzler J., and Owens M.J. Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity. Biol. Psychiatry 55 (2004) 320-322
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 320-322
-
-
Vaishnavi, S.N.1
Nemeroff, C.B.2
Plott, S.J.3
Rao, S.G.4
Kranzler, J.5
Owens, M.J.6
-
48
-
-
0032822775
-
Precision and comparability of adverse event rates of newer antidepressants
-
Vida S., and Looper K. Precision and comparability of adverse event rates of newer antidepressants. J. Clin. Psychopharmacol. 19 (1999) 416-426
-
(1999)
J. Clin. Psychopharmacol.
, vol.19
, pp. 416-426
-
-
Vida, S.1
Looper, K.2
-
49
-
-
12444329713
-
Design, synthesis, and activity of novel cis- and trans-3,6-disubstituted pyran biomimetics of 3,6-disubstituted piperidine as potential ligands for the dopamine transporter
-
Zhang S., Reith M.E., and Dutta A.K. Design, synthesis, and activity of novel cis- and trans-3,6-disubstituted pyran biomimetics of 3,6-disubstituted piperidine as potential ligands for the dopamine transporter. Bioorg. Med. Chem. Lett. 13 (2003) 1591-1595
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 1591-1595
-
-
Zhang, S.1
Reith, M.E.2
Dutta, A.K.3
-
50
-
-
7444243985
-
Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters
-
Zhang S., Zhen J., Reith M.E., and Dutta A.K. Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters. Bioorg. Med. Chem. 12 (2004) 6301-6315
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 6301-6315
-
-
Zhang, S.1
Zhen, J.2
Reith, M.E.3
Dutta, A.K.4
-
51
-
-
22844451687
-
Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner
-
Zhang S., Zhen J., Reith M.E., and Dutta A.K. Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner. J. Med. Chem. 48 (2005) 4962-4971
-
(2005)
J. Med. Chem.
, vol.48
, pp. 4962-4971
-
-
Zhang, S.1
Zhen, J.2
Reith, M.E.3
Dutta, A.K.4
-
52
-
-
33745865926
-
Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters
-
Zhang S., Fernandez F., Hazeldine S., Deschamps J., Zhen J., Reith M.E., and Dutta A.K. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters. J. Med. Chem. 49 (2006) 4239-4247
-
(2006)
J. Med. Chem.
, vol.49
, pp. 4239-4247
-
-
Zhang, S.1
Fernandez, F.2
Hazeldine, S.3
Deschamps, J.4
Zhen, J.5
Reith, M.E.6
Dutta, A.K.7
|