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Volumn 313, Issue 3, 2005, Pages 1361-1369

Development of a rationally designed, low abuse potential, biogenic amine releaser that suppresses cocaine self-administration

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPTHYL 2 AMINOPROPANE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; BIOGENIC AMINE; CENTRAL STIMULANT AGENT; COCAINE; DOPAMINE; METHAMPHETAMINE; PAL 287; SEROTONIN; SEROTONIN AGONIST; UNCLASSIFIED DRUG;

EID: 19444387962     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.082503     Document Type: Article
Times cited : (80)

References (53)
  • 1
    • 0028968941 scopus 로고
    • Diethylpropion pharmacotherapeutic adjuvant therapy for inpatient treatment of cocaine dependence: A test of the cocaine-agonist hypothesis
    • Alim TN, Rosse RB, Vocci FJ Jr, Lindquist T, and Deutsch SI (1995) Diethylpropion pharmacotherapeutic adjuvant therapy for inpatient treatment of cocaine dependence: a test of the cocaine-agonist hypothesis. Clin Neuropharmacol 18:183-195.
    • (1995) Clin Neuropharmacol , vol.18 , pp. 183-195
    • Alim, T.N.1    Rosse, R.B.2    Vocci Jr., F.J.3    Lindquist, T.4    Deutsch, S.I.5
  • 2
    • 10444238563 scopus 로고    scopus 로고
    • Drug abuse trends among youth in the United States
    • Banken JA (2004) Drug abuse trends among youth in the United States. Ann NY Acad Sci 1025:465-471.
    • (2004) Ann NY Acad Sci , vol.1025 , pp. 465-471
    • Banken, J.A.1
  • 3
    • 0034113934 scopus 로고    scopus 로고
    • Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: Therapeutic implications
    • Baumann MH, Ayestas MA, Dersch CM, Brockington A, Rice KC, and Rothman RB (2000) Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: therapeutic implications. Synapse 36:102-113.
    • (2000) Synapse , vol.36 , pp. 102-113
    • Baumann, M.H.1    Ayestas, M.A.2    Dersch, C.M.3    Brockington, A.4    Rice, K.C.5    Rothman, R.B.6
  • 4
    • 0035083653 scopus 로고    scopus 로고
    • 1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain
    • Baumann MH, Ayestas MA, Dersch CM, and Rothman RB (2001) 1-(m-Chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain. Neuropsychopharmacology 24:492-501.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 492-501
    • Baumann, M.H.1    Ayestas, M.A.2    Dersch, C.M.3    Rothman, R.B.4
  • 5
    • 0032191731 scopus 로고    scopus 로고
    • Alterations in serotonergic responsiveness during cocaine withdrawal in rats: Similarities to major depression in humans
    • Baumann MH and Rothman RB (1998) Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to major depression in humans. Biol Psychiatry 44:578-591.
    • (1998) Biol Psychiatry , vol.44 , pp. 578-591
    • Baumann, M.H.1    Rothman, R.B.2
  • 6
    • 0019025720 scopus 로고
    • Effect of fenfluramine and norfenfluramine stereoisomers on stimulant effects of d-amphetamine and apomorphine in the rat
    • Bendotti C, Borsini F, Zanini MG, Samanin R, and Garattini S (1980) Effect of fenfluramine and norfenfluramine stereoisomers on stimulant effects of d-amphetamine and apomorphine in the rat. Pharmacol Res Commun 12:567-574.
    • (1980) Pharmacol Res Commun , vol.12 , pp. 567-574
    • Bendotti, C.1    Borsini, F.2    Zanini, M.G.3    Samanin, R.4    Garattini, S.5
  • 7
    • 0030762572 scopus 로고    scopus 로고
    • Do recombinant receptor assays provide affinity and potency estimates?
    • Bockaert J, Brand C, and Journot L (1997) Do recombinant receptor assays provide affinity and potency estimates? Ann NY Acad Sci 812:55-70.
    • (1997) Ann NY Acad Sci , vol.812 , pp. 55-70
    • Bockaert, J.1    Brand, C.2    Journot, L.3
  • 8
    • 1642488894 scopus 로고    scopus 로고
    • Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats
    • Burmeister JJ, Lungren EM, Kirschner KF, and Neisewander JL (2004) Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats. Neuropsychopharmacology 29:660-668.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 660-668
    • Burmeister, J.J.1    Lungren, E.M.2    Kirschner, K.F.3    Neisewander, J.L.4
  • 9
    • 0025093520 scopus 로고
    • Fluoxetine reduces intravenous cocaine self-administration in rats
    • Carroll ME, Lac ST, Asencio M, and Kragh R (1990) Fluoxetine reduces intravenous cocaine self-administration in rats. Pharmacol Biochem Behav 35:237-244.
    • (1990) Pharmacol Biochem Behav , vol.35 , pp. 237-244
    • Carroll, M.E.1    Lac, S.T.2    Asencio, M.3    Kragh, R.4
  • 10
    • 0036175937 scopus 로고    scopus 로고
    • Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys
    • Czoty PW, Ginsburg BC, and Howell LL (2002) Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys. J Pharmacol Exp Ther 300:831-837.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 831-837
    • Czoty, P.W.1    Ginsburg, B.C.2    Howell, L.L.3
  • 11
    • 0022405110 scopus 로고
    • New concepts in cocaine addiction: The dopamine depletion hypothesis
    • Dackis CA and Gold MS (1985) New concepts in cocaine addiction: the dopamine depletion hypothesis. Neurosci Biobehav Rev 9:469-477.
    • (1985) Neurosci Biobehav Rev , vol.9 , pp. 469-477
    • Dackis, C.A.1    Gold, M.S.2
  • 12
    • 0036592008 scopus 로고    scopus 로고
    • Opponent interactions between serotonin and dopamine
    • Daw ND, Kakade S, and Dayan P (2002) Opponent interactions between serotonin and dopamine. Neural Netw 15:603-616.
    • (2002) Neural Netw , vol.15 , pp. 603-616
    • Daw, N.D.1    Kakade, S.2    Dayan, P.3
  • 15
    • 0022591327 scopus 로고
    • Abstinence symptomatology and psychiatric diagnosis in cocaine abusers
    • Gawin FH and Kleber HD (1986) Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Arch Gen Psychiatry 43:107-113.
    • (1986) Arch Gen Psychiatry , vol.43 , pp. 107-113
    • Gawin, F.H.1    Kleber, H.D.2
  • 17
    • 0031006690 scopus 로고    scopus 로고
    • Phentermine/fenfluramine decreases cocaine self-administration in rhesus monkeys
    • Glowa JR, Rice KC, Matecka D, and Rothman RB (1997) Phentermine/ fenfluramine decreases cocaine self-administration in rhesus monkeys. Neuroreport 8:1347-1351.
    • (1997) Neuroreport , vol.8 , pp. 1347-1351
    • Glowa, J.R.1    Rice, K.C.2    Matecka, D.3    Rothman, R.B.4
  • 18
    • 0001684077 scopus 로고    scopus 로고
    • The rate hypothesis and agonist substitution approaches to cocaine abuse treatment
    • Gorelick DA (1998) The rate hypothesis and agonist substitution approaches to cocaine abuse treatment. Adv Pharmacol 42:995-997.
    • (1998) Adv Pharmacol , vol.42 , pp. 995-997
    • Gorelick, D.A.1
  • 20
  • 22
    • 0028849333 scopus 로고
    • Nicotine medications for smoking cessation
    • Henningfield JE (1995) Nicotine medications for smoking cessation. N Engl J Med 333:1196-1203.
    • (1995) N Engl J Med , vol.333 , pp. 1196-1203
    • Henningfield, J.E.1
  • 23
    • 0029549859 scopus 로고
    • Serotonergic modulation of the behavioral effects of cocaine in the squirrel monkey
    • Howell LL and Byrd LD (1995) Serotonergic modulation of the behavioral effects of cocaine in the squirrel monkey. J Pharmacol Exp Ther 275:1551-1559.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1551-1559
    • Howell, L.L.1    Byrd, L.D.2
  • 25
    • 0037488246 scopus 로고    scopus 로고
    • The validity of the reinstatement model of craving and relapse to drug use
    • Katz JL and Higgins ST (2003) The validity of the reinstatement model of craving and relapse to drug use. Psychopharmacology (Berl) 168:21-30.
    • (2003) Psychopharmacology (Berl) , vol.168 , pp. 21-30
    • Katz, J.L.1    Higgins, S.T.2
  • 26
    • 0030179225 scopus 로고    scopus 로고
    • Opiates, opioids and addiction
    • Kreek MJ (1996) Opiates, opioids and addiction. Mol Psychiatry 1:232-254.
    • (1996) Mol Psychiatry , vol.1 , pp. 232-254
    • Kreek, M.J.1
  • 27
    • 2942536131 scopus 로고    scopus 로고
    • Addressing the need for treatment paradigms for drug-abusing patients with multiple morbidities
    • Kresina TF, Normand J, Khalsa J, Mitty J, Flanigan T, and Francis H (2004) Addressing the need for treatment paradigms for drug-abusing patients with multiple morbidities. Clin Infect Dis 38 (Suppl 5):S398-S401.
    • (2004) Clin Infect Dis , vol.38 , Issue.SUPPL. 5
    • Kresina, T.F.1    Normand, J.2    Khalsa, J.3    Mitty, J.4    Flanigan, T.5    Francis, H.6
  • 28
    • 0142153196 scopus 로고    scopus 로고
    • Neurobiology of suicidal behaviour
    • Mann JJ (2003) Neurobiology of suicidal behaviour. Nat Rev Neurosci 4:819-828.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 819-828
    • Mann, J.J.1
  • 29
    • 0036181586 scopus 로고    scopus 로고
    • Effects of n-opioid agonists on cocaine- and food-maintained responding and cocaine discrimination in rhesus monkeys: Role of μ-agonist efficacy
    • Negus SS and Mello NK (2002) Effects of n-opioid agonists on cocaine- and food-maintained responding and cocaine discrimination in rhesus monkeys: role of μ-agonist efficacy. J Pharmacol Exp Ther 300:1111-1121.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 1111-1121
    • Negus, S.S.1    Mello, N.K.2
  • 30
    • 0012739591 scopus 로고    scopus 로고
    • Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a progressive-ratio schedule in rhesus monkeys
    • Negus SS and Mello NK (2003a) Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a progressive-ratio schedule in rhesus monkeys. Psychopharmacology (Bert) 167:324-332.
    • (2003) Psychopharmacology (Bert) , vol.167 , pp. 324-332
    • Negus, S.S.1    Mello, N.K.2
  • 31
    • 0037401754 scopus 로고    scopus 로고
    • Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a second-order schedule in rhesus monkeys
    • Negus SS and Mello NK (2003b) Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a second-order schedule in rhesus monkeys. Drug Alcohol Depend 70:39-52.
    • (2003) Drug Alcohol Depend , vol.70 , pp. 39-52
    • Negus, S.S.1    Mello, N.K.2
  • 32
    • 0031854682 scopus 로고    scopus 로고
    • Evaluation of the conditioned reinforcing effects of phentermine and fenfluramine in the rat: Concordance with clinical studies
    • Rea WP, Rothman RB, and Shippenberg TS (1998) Evaluation of the conditioned reinforcing effects of phentermine and fenfluramine in the rat: concordance with clinical studies. Synapse 30:107-111.
    • (1998) Synapse , vol.30 , pp. 107-111
    • Rea, W.P.1    Rothman, R.B.2    Shippenberg, T.S.3
  • 34
    • 0035993478 scopus 로고    scopus 로고
    • Therapeutic and adverse actions of serotonin transporter substrates
    • Rothman RB and Baumann M (2002) Therapeutic and adverse actions of serotonin transporter substrates. Pharmacol Ther 95:73-88.
    • (2002) Pharmacol Ther , vol.95 , pp. 73-88
    • Rothman, R.B.1    Baumann, M.2
  • 35
    • 0034517918 scopus 로고    scopus 로고
    • Neurochemical mechanisms of phentermine and fenfluramine: Therapeutic and adverse effects
    • Rothman RB and Baumann MH (2000) Neurochemical mechanisms of phentermine and fenfluramine: therapeutic and adverse effects. Drug Dev Res 51:52-65.
    • (2000) Drug Dev Res , vol.51 , pp. 52-65
    • Rothman, R.B.1    Baumann, M.H.2
  • 36
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman RB, Baumann MH, Dersch CM, Romero DV, Rice KC, Carroll FI, and Partilla JS (2001) Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39:32-41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1    Baumann, M.H.2    Dersch, C.M.3    Romero, D.V.4    Rice, K.C.5    Carroll, F.I.6    Partilla, J.S.7
  • 38
    • 0036296867 scopus 로고    scopus 로고
    • Appetite suppressants as agonist substitution therapies for stimulant dependence
    • Rothman RB, Blough BE, and Baumann MH (2002a) Appetite suppressants as agonist substitution therapies for stimulant dependence. Ann NY Acad Sci 965:109-126.
    • (2002) Ann NY Acad Sci , vol.965 , pp. 109-126
    • Rothman, R.B.1    Blough, B.E.2    Baumann, M.H.3
  • 39
    • 0028434555 scopus 로고
    • Combined use of fenfluramine and phentermine in the treatment of cocaine addiction: A pilot case series
    • Rothman RB, Gendron TM, and Hitzig P (1994) Combined use of fenfluramine and phentermine in the treatment of cocaine addiction: a pilot case series. J Subst Abuse Treat 11:273-275.
    • (1994) J Subst Abuse Treat , vol.11 , pp. 273-275
    • Rothman, R.B.1    Gendron, T.M.2    Hitzig, P.3
  • 40
    • 0037188748 scopus 로고    scopus 로고
    • Interaction of the anorectic medication, phendimetrazine and its metabolites with monoamine transporters in rat brain
    • Rothman RB, Katsnelson M, Vu N, Partilla JS, Dersch CM, Blough BE, and Baumann MH (2002b) Interaction of the anorectic medication, phendimetrazine and its metabolites with monoamine transporters in rat brain. Eur J Pharmacol 447:51-57.
    • (2002) Eur J Pharmacol , vol.447 , pp. 51-57
    • Rothman, R.B.1    Katsnelson, M.2    Vu, N.3    Partilla, J.S.4    Dersch, C.M.5    Blough, B.E.6    Baumann, M.H.7
  • 41
    • 0038779278 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro
    • Setola V, Hufeisen SJ, Grande-Allen KJ, Vesely I, Glennon RA, Blough B, Rothman RB, and Roth BL (2003) 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. Mol Pharmacol 63:1223-1229.
    • (2003) Mol Pharmacol , vol.63 , pp. 1223-1229
    • Setola, V.1    Hufeisen, S.J.2    Grande-Allen, K.J.3    Vesely, I.4    Glennon, R.A.5    Blough, B.6    Rothman, R.B.7    Roth, B.L.8
  • 42
    • 3142680841 scopus 로고    scopus 로고
    • Pharmacotherapies for problematic psychostimulant use: A review of current research
    • Shearer J and Cowing LR (2004) Pharmacotherapies for problematic psychostimulant use: a review of current research. Drug Alcohol Rev 23:203-211.
    • (2004) Drug Alcohol Rev , vol.23 , pp. 203-211
    • Shearer, J.1    Cowing, L.R.2
  • 43
    • 0041703183 scopus 로고    scopus 로고
    • Pilot randomized double blind placebo-controlled study of dexamphetamine for cocaine dependence
    • Shearer J, Wodak A, van Seek I, Mattick RP, and Lewis J (2003) Pilot randomized double blind placebo-controlled study of dexamphetamine for cocaine dependence. Addiction 98:1137-1141.
    • (2003) Addiction , vol.98 , pp. 1137-1141
    • Shearer, J.1    Wodak, A.2    Van Seek, I.3    Mattick, R.P.4    Lewis, J.5
  • 45
    • 0242467864 scopus 로고    scopus 로고
    • Pharmacological treatments for heroin and cocaine addiction
    • van den Brink W and van Ree JM (2003) Pharmacological treatments for heroin and cocaine addiction. Eur Neuropsychopharmacol 13:476-487.
    • (2003) Eur Neuropsychopharmacol , vol.13 , pp. 476-487
    • Van Den Brink, W.1    Van Ree, J.M.2
  • 46
    • 0032962859 scopus 로고    scopus 로고
    • Reduced satiating effect of d-fenfluramine in serotonin 5-HTE(2C) receptor mutant mice
    • Vickers SP, Clifton PG, Dourish CT, and Tecott LH (1999) Reduced satiating effect of d-fenfluramine in serotonin 5-HTE(2C) receptor mutant mice. Psychopharmacology 143:309-314.
    • (1999) Psychopharmacology , vol.143 , pp. 309-314
    • Vickers, S.P.1    Clifton, P.G.2    Dourish, C.T.3    Tecott, L.H.4
  • 47
    • 0031037946 scopus 로고    scopus 로고
    • Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine
    • Walsh SL and Cunningham KA (1997) Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology 130:41-58.
    • (1997) Psychopharmacology , vol.130 , pp. 41-58
    • Walsh, S.L.1    Cunningham, K.A.2
  • 48
    • 0033942030 scopus 로고    scopus 로고
    • Modulation of intravenous cocaine effects by chronic oral cocaine in humans
    • Walsh SL, Haberny KA, and Bigelow GE (2000) Modulation of intravenous cocaine effects by chronic oral cocaine in humans. Psychopharmacology 150:361-373.
    • (2000) Psychopharmacology , vol.150 , pp. 361-373
    • Walsh, S.L.1    Haberny, K.A.2    Bigelow, G.E.3
  • 50
    • 2942518236 scopus 로고    scopus 로고
    • Reinforcing effect of pseudoephedrine isomers and the mechanism of action
    • Wee S, Ordway GA, and Woolverton WL (2004) Reinforcing effect of pseudoephedrine isomers and the mechanism of action. Eur J Pharmacol 493:117-125.
    • (2004) Eur J Pharmacol , vol.493 , pp. 117-125
    • Wee, S.1    Ordway, G.A.2    Woolverton, W.L.3
  • 51
    • 0029888444 scopus 로고    scopus 로고
    • Neurobiology of addiction
    • Wise RA (1996) Neurobiology of addiction. Curr Opin Neurobiol 6:243-251.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 243-251
    • Wise, R.A.1
  • 52
    • 0032988931 scopus 로고    scopus 로고
    • Effects of phentermine on responding maintained under multiple fixed-ratio schedules of food-presentation and cocaine-delivery in the rhesus monkey
    • Wojnicki FHE, Rothman RB, Rice KC, and Glowa JR (1999) Effects of phentermine on responding maintained under multiple fixed-ratio schedules of food-presentation and cocaine-delivery in the rhesus monkey. J Pharmacol Exp Ther 288:550-560.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 550-560
    • Wojnicki, F.H.E.1    Rothman, R.B.2    Rice, K.C.3    Glowa, J.R.4
  • 53
    • 0016398566 scopus 로고
    • Fenfluramine: Amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey
    • Woods JH and Tessel RE (1974) Fenfluramine: amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey. Science (Wash DC) 185:1067-1069.
    • (1974) Science (Wash DC) , vol.185 , pp. 1067-1069
    • Woods, J.H.1    Tessel, R.E.2


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