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Helvetica Chimica Acta

Volumn 92, Issue 7, 2009, Pages 1385-1403

Synthesis and anti-HIV-1 evaluation of new Sonogashira-modified emivirine (MKC-442) analogues

(6) Danel, Krzysztof a,c Jørgensen, Per T a Pedersen, Erik B a La Colla, Paolo b Collu, Gabriella b Loddo, Roberta a

a UNIVERSITY OF SOUTHERN DENMARK (Denmark)

b Dipartimento di Scienze e Tecnologie Biomediche (Italy)

c UNIVERSITY OF AGRICULTURE IN KRAKOW (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE COMPOUNDS; ANTI-HIV; C-COUPLING REACTIONS; CLICK CHEMISTRY; DEPROTECTION; ISOMERIC ALCOHOLS; METHYL DERIVATIVES; METHYL GROUP; PROPARGYL ALCOHOL; RESISTANT MUTANTS; SONOGASHIRA COUPLING; SONOGASHIRA REACTIONS;

ACETYLENE; ALDEHYDES; BROMINE; CHEMICAL BONDS; GRAFTING (CHEMICAL); ORGANIC POLYMERS; PALLADIUM; SILANES;

SYNTHESIS (CHEMICAL);

1 [[(3 (3 [[(TERT BUTYL)DIPHENYLSILYLOXY]METHYL]PHENYL)PROP 2 YNYL)OXY]METHYL) 6 (3,5 DIMETHYLBENZYL)URACIL; 1 [[(3 (4 AMINOPHENYL)PROP 2 YNYL)OXY)METHYL] 5 ETHYL 6 (2 METHYLBENZYL)URACIL; 1 [[(3 (4 AMINOPHENYL)PROP 2 YNYL)OXY)METHYL] 6 (3,5 DIMETHYLBENZYL) 5 ETHYLURACIL; 1 [[(3 [3 [(TERT BUTYL)DIPHENYLSILYLOXY]PHENYL]PROP 2 YNYL)OXY]METHYL] 6 (3,5 DIMETHYLBENZYL) 5 ETHYLURACIL; 1 [[(3 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]PROP 2 YNYL)OXY]METHYL] 6 (3,5 DIMETHYLBENZYL) 5 ETHYLURACIL; 1 [[(3 [4 [(TERT BUTYL)DIPHENYLSILYLOXY]PHENYL]PROP 2 YNYL)OXY]METHYL] 6 (3,5 DIMETHYLBENZYL) 5 ETHYLURACIL; 1 [[(3 [4 [[(TERT BUTYL)DIPHENYLSILYLOXY]METHYL]PHENYL)PROP 2 YNYL]OXY]METHYL] 6 (3,5 DIMETHYLBENZYL) 5 ETHYLURACIL; 1 [[(6 [ (TERT BUTYL)DIPHENYLSILYLOXY]HEXA 2,4 DIYNYL)OXY]METHYL] 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1H PYRIMIDINE 2,4 DIONE; 2 BROMO N [4 (3 [(5 ETHYL 6 (2 METHYLBENZYL) 2,4 DIOXO 3,4 DIHYDRO 2H PYRIMIDIN 1 YL)METHOXY]PROP 1 YNYL)PHENYL]ACETAMIDE; 2 BROMO N [4 (3 [(6 ( 3,5 DIMETHYLBENZYL) 5 ETHYL 2,4 DIOXO 3,4 DIHYDRO 2H PYRIMIDIN 1 YL)METHOXY]PROP 1 YNYL)PHENYL]ACETAMIDE; 2 BROMO N [4 (3 [(6 (3,5 DIMETHYLBENZYL) 5 ETHYL 3,4 DIHYDRO 2,4 DIOXO 2H PYRIMIDIN 1 YL)METHOXY]PROP 1 YNYL)PHENYL]ACETAMIDE; 5 ETHYL 1 [[(3 (9H FLUOREN 2 YL)PROP 2 YNYL)OXY)METHYL] 6 (2 METHYLBENZYL)URACIL; 5 ETHYL 6 (2 METHYLBENZYL) 1 [(PROP 2 YNYLOXY)METHYL]URACIL; 5 ETHYL 6 (2 METHYLBENZYL) 1 [[(3 NAPHTHALEN 1 YLPROP 2 YNYL)OXY]METHYL]URACIL; 5 ETHYL 6 (2 METHYLBENZYL) 1 [[(3 PHENYLPROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 (2 NITROPHENYL)PROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 (3 CYANOPHENYL)PROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 (4 NITROPHENYL)PROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 [(2 METHYLSULFANYL)PHENYL]PROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 [2 (TRIFLUOROMETHYL)PHENYL]PROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 PHENANTHREN 9 YLPROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 PHENYLPROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 PYRAZIN 2 YLPROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 PYRIDIN 3 YLPROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(3 THIEN 2 YLPROP 2 YNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYL 1 [[(6 HYDROXYHEXA 2,4 DIYNYL)OXY]METHYL]URACIL; 6 (3,5 DIMETHYLBENZYL) 5 ETHYLURACIL; EMIVIRINE; N [4 (3 [(5 ETHYL 6 (2 METHYLBENZYL) 3,4 DIHYDRO 2,4 DIOXO 2H PYRIMIDIN 1 YL)METHOXY]PROP 1 YNYL)PHENYL] 2,2,2 TRIFLUOROACETAMIDE; N [4 (3 [(6 (3,5 DIMETHYLBENZYL) 5 ETHYL 3,4 DIHYDRO 2,4 DIOXO 2H PYRIMIDIN 1 YL)METHOXY]PROP 1 YNYL)PHENYL] 2,2,2 TRIFLUOROACETAMIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMISTRY; CONTROLLED STUDY; DEPROTECTION REACTION; EVALUATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTANT; OXIDATION; PRIORITY JOURNAL; SONOGASHIRA REACTION; SYNTHESIS;

EID: 67749116517 PISSN: 0018019X EISSN: None Source Type: Journal
DOI: 10.1002/hlca.200900039 Document Type: Article

Times cited : (5)

References (61)

1
- 0020596551
- F. Barre-Sinoussi, J. C. Chermann, F. Rey, M. T. Nugeyre, S. Chamaret, J. Gruest, C. Dauguet, C. Axler-Blin, F. Vezinet-Brun, C. Rouzioux, W. Rozenbaum, L. Montagnier, Science 1983, 220, 868.
- (1983) Science , vol.220 , pp. 868
- Barre-Sinoussi, F.¹ Chermann, J.C.² Rey, F.³ Nugeyre, M.T.⁴ Chamaret, S.⁵ Gruest, J.⁶ Dauguet, C.⁷ Axler-Blin, C.⁸ Vezinet-Brun, F.⁹ Rouzioux, C.¹⁰ Rozenbaum, W.¹¹ Montagnier, L.¹²

2
- 0021707074
- S. Broder, R. C. Gallo, N. Engl. J. Med. 1984, 311, 1292.
- (1984) N. Engl. J. Med. , vol.311 , pp. 1292
- Broder, S.¹ Gallo, R.C.²

3
- 0036846898
- E. De Clercq, Med. Res. Rev. 2002, 22, 531.
- (2002) Med. Res. Rev. , vol.22 , pp. 531
- De Clercq, E.¹

4
- 2942627670
- E. De Clercq, Int. J. Biochem. Cell Biol. 2004, 36, 1800.
- (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 1800
- De Clercq, E.¹

5
- 0036104758
- G. Campiani, A. Ramunno, G. Maga, V. Nacci, C. Fattorusso, B. Catalanotti, E. Morelli, E. Novellino, Curr. Pharm. Des. 2002, 8, 615.
- (2002) Curr. Pharm. Des. , vol.8 , pp. 615
- Campiani, G.¹ Ramunno, A.² Maga, G.³ Nacci, V.⁴ Fattorusso, C.⁵ Catalanotti, B.⁶ Morelli, E.⁷ Novellino, E.⁸

6
- 2342531101
- E. De Clercq, J. Clin. Virol. 2004, 30, 115.
- (2004) J. Clin. Virol. , vol.30 , pp. 115
- De Clercq, E.¹

7
- 12144265244
- E. De Clercq, Chem. Biodiversity 2004, 1, 44.
- (2004) Chem. Biodiversity , vol.1 , pp. 44
- De Clercq, E.¹

8
- 0035368238
- Y. Hsiou, J. Ding, K. Das, A. D. Clark Jr., P. L. Boyer, P. Lewi, P. A. J. Janssen, J.-P. Kleim, M. Rösner, S. H. Hughes, E. Arnold, J. Mol. Biol. 2001, 309, 437.
- (2001) J. Mol. Biol. , vol.309 , pp. 437
- Hsiou, Y.¹ Ding, J.² Das, K.³ Clark Jr., A.D.⁴ Boyer, P.L.⁵ Lewi, P.⁶ Janssen, P.A.J.⁷ Kleim, J.-P.⁸ Rösner, M.⁹ Hughes, S.H.¹⁰ Arnold, E.¹¹

9
- 0035965124
- J. Ren, C. Nichols, L. Bid, P. Chamberlain, K. Weaver, S. Short, D. I. Stuart, D. K. Stammers, J. Mol. Biol. 2001, 312, 795.
- (2001) J. Mol. Biol. , vol.312 , pp. 795
- Ren, J.¹ Nichols, C.² Bid, L.³ Chamberlain, P.⁴ Weaver, K.⁵ Short, S.⁶ Stuart, D.I.⁷ Stammers, D.K.⁸

10
- 0037137588
- N. R. El-Brollosy, P. T. Jørgensen, B. Dahan, A. M. Boel, E. B. Pedersen, C. Nielsen, J. Med. Chem. 2002, 45, 5721.
- (2002) J. Med. Chem. , vol.45 , pp. 5721
- El-Brollosy, N.R.¹ Jørgensen, P.T.² Dahan, B.³ Boel, A.M.⁴ Pedersen, E.B.⁵ Nielsen, C.⁶

11
- 0033535074
- I. Sugimoto, S. Shuto, S. Mori, S. Shigeta, A. Matsuda, Bioorg. Med. Chem. Lett. 1999, 9, 385;
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 385
- Sugimoto, I.¹ Shuto, S.² Mori, S.³ Shigeta, S.⁴ Matsuda, A.⁵

12
- 4344602617
- H. Hayakawa, S. Kohgo, K. Kitano, N. Ashida, E. Kodama, H. Mitsuya, H. Ohrui, Antiviral Chem. Chemother. 2004, 15, 169.
- (2004) Antiviral Chem. Chemother. , vol.15 , pp. 169
- Hayakawa, H.¹ Kohgo, S.² Kitano, K.³ Ashida, N.⁴ Kodama, E.⁵ Mitsuya, H.⁶ Ohrui, H.⁷

13
- 0037943974
- E.-i. Negishi, L. Anastasia, Chem. Rev. 2003, 103, 1979.
- (2003) Chem. Rev. , vol.103 , pp. 1979
- Negishi, E.-I.¹ Anastasia, L.²

14
- 0037944068
- L. A. Agrofoglio, I. Gillaizeau, Y. Saito, Chem. Rev. 2003, 103, 1875.
- (2003) Chem. Rev. , vol.103 , pp. 1875
- Agrofoglio, L.A.¹ Gillaizeau, I.² Saito, Y.³

15
- 5644293224
- W. Flasche, C. Cismas, A. Herrmann, J. Liebscher, Synthesis 2004, 14, 2335.
- (2004) Synthesis , vol.14 , pp. 2335
- Flasche, W.¹ Cismas, C.² Herrmann, A.³ Liebscher, J.⁴

16
- 11244333172
- A. Ciurea, C. Fossey, D. Gavriliu, Z. Delbederi, E. Sugeac, D. Laduree, S. Schmidt, G. Laumond, A.-M. Aubertin, J. Enzyme Inhib. Med. Chem. 2004, 19, 511.
- (2004) J. Enzyme Inhib. Med. Chem. , vol.19 , pp. 511
- Ciurea, A.¹ Fossey, C.² Gavriliu, D.³ Delbederi, Z.⁴ Sugeac, E.⁵ Laduree, D.⁶ Schmidt, S.⁷ Laumond, G.⁸ Aubertin, A.-M.⁹

17
- 12844249473
- F. Amblard, V. Aucagne, P. Guenot, R. F. Schinazi, L. A. Agrofoglio, Bioorg. Med. Chem. 2005, 13, 1239.
- (2005) Bioorg. Med. Chem. , vol.13 , pp. 1239
- Amblard, F.¹ Aucagne, V.² Guenot, P.³ Schinazi, R.F.⁴ Agrofoglio, L.A.⁵

18
- 18844401130
- G. Arnott, R. Hunter, L. Mbeki, E. Mohamed, Tetrahedron Lett. 2005, 46, 4023.
- (2005) Tetrahedron Lett. , vol.46 , pp. 4023
- Arnott, G.¹ Hunter, R.² Mbeki, L.³ Mohamed, E.⁴

19
- 33947727729
- R. Hunter, C. I. Muhanji, I. Hale, C. M. Bailey, A. Basavapathruni, K. S. Anderson, Bioorg. Med. Chem. Lett. 2007, 17, 2614.
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 2614
- Hunter, R.¹ Muhanji, C.I.² Hale, I.³ Bailey, C.M.⁴ Basavapathruni, A.⁵ Anderson, K.S.⁶

20
- 0031449527
- D. B. Kireev, J. R. Chrétien, D. S. Grierson, C. Monneret, J. Med. Chem. 1997, 40, 4257.
- (1997) J. Med. Chem. , vol.40 , pp. 4257
- Kireev, D.B.¹ Chrétien, J.R.² Grierson, D.S.³ Monneret, C.⁴

21
- 0033524008
- A. L. Hopkins, J. Ren, H. Tanaka, M. Baba, M. Okamato, D. I. Stuart, D. K. Stammers, J. Med. Chem. 1999, 42, 4500.
- (1999) J. Med. Chem. , vol.42 , pp. 4500
- Hopkins, A.L.¹ Ren, J.² Tanaka, H.³ Baba, M.⁴ Okamato, M.⁵ Stuart, D.I.⁶ Stammers, D.K.⁷

22
- 38049054113
- K. Danel, L. M. Larsen, E. B. Pedersen, G. Sanna, P. La Colla, R. Loddo, Bioorg. Med. Chem. 2008, 16, 511.
- (2008) Bioorg. Med. Chem. , vol.16 , pp. 511
- Danel, K.¹ Larsen, L.M.² Pedersen, E.B.³ Sanna, G.⁴ La Colla, P.⁵ Loddo, R.⁶

23
- 67749130718
- M. I. Bardamova, I. L. Kotlyarevskii, Z. P. Trotsenko, Izv. Akad. Nauk. SSSR, Ser. Khim. 1984, 821.
- (1984) Izv. Akad. Nauk. SSSR, Ser. Khim. , pp. 821
- Bardamova, M.I.¹ Kotlyarevskii, I.L.² Trotsenko, Z.P.³

24
- 15444380767
- F. Maya, S. H. Chanteau, L. Cheng, M. P. Stewart, J. M. Tour, Chem. Mater. 2005, 17, 1331.
- (2005) Chem. Mater. , vol.17 , pp. 1331
- Maya, F.¹ Chanteau, S.H.² Cheng, L.³ Stewart, M.P.⁴ Tour, J.M.⁵

25
- 0029939554
- K. Danel, E. Larsen, E. B. Pedersen, B. F. Vestergaard, C. J. Nielsen, J. Med. Chem. 1996, 39, 2427.
- (1996) J. Med. Chem. , vol.39 , pp. 2427
- Danel, K.¹ Larsen, E.² Pedersen, E.B.³ Vestergaard, B.F.⁴ Nielsen, C.J.⁵

26
- 0042564799
- G. Meng, Y.-P. He, F.-E. Chen, Synth. Commun. 2003, 33, 2593.
- (2003) Synth. Commun. , vol.33 , pp. 2593
- Meng, G.¹ He, Y.-P.² Chen, F.-E.³

27
- 0001240638
- A. P. Melissaris, M. H. Litt, J. Org. Chem. 1994, 59, 5818.
- (1994) J. Org. Chem. , vol.59 , pp. 5818
- Melissaris, A.P.¹ Litt, M.H.²

28
- 0034676329
- K. A. Leonard, J. P. Hall, M. I. Nelen, S. R. Davies, S. O. Gollnick, S. Camacho, A. R. Oseroff, S. L. Gibson, R. Hilf, M. R. A. Detty, J. Med. Chem. 2000, 43, 4488.
- (2000) J. Med. Chem. , vol.43 , pp. 4488
- Leonard, K.A.¹ Hall, J.P.² Nelen, M.I.³ Davies, S.R.⁴ Gollnick, S.O.⁵ Camacho, S.⁶ Oseroff, A.R.⁷ Gibson, S.L.⁸ Hilf, R.⁹ Detty, M.R.A.¹⁰

29
- 0030794877
- K. Danel, E. B. Pedersen, C. Nielsen, Synthesis 1997, 9, 1021.
- (1997) Synthesis , vol.9 , pp. 1021
- Danel, K.¹ Pedersen, E.B.² Nielsen, C.³

30
- 0031942724
- K. Danel, E. B. Pedersen, C. Nielsen, J. Med. Chem. 1998, 41, 191.
- (1998) J. Med. Chem. , vol.41 , pp. 191
- Danel, K.¹ Pedersen, E.B.² Nielsen, C.³

31
- 0035073305
- L. Petersen, E. B. Pedersen, C. Nielsen, Synthesis 2001, 4, 559.
- (2001) Synthesis , vol.4 , pp. 559
- Petersen, L.¹ Pedersen, E.B.² Nielsen, C.³

32
- 57249109794
- L. Petersen, T. H. Hansen, N. M. Khalifa, P. T. Jørgensen, E. B. Pedersen, C. Nielsen, Monatsh. Chem. 2002, 133, 1031.
- (2002) Monatsh. Chem. , vol.133 , pp. 1031
- Petersen, L.¹ Hansen, T.H.² Khalifa, N.M.³ Jørgensen, P.T.⁴ Pedersen, E.B.⁵ Nielsen, C.⁶

33
- 0028918824
- M. S. Tang, L. J. Askonas, T. M. Penning, Biochemistry 1995, 34, 808.
- (1995) Biochemistry , vol.34 , pp. 808
- Tang, M.S.¹ Askonas, L.J.² Penning, T.M.³

34
- 0026337650
- L. J. Askonas, T. M. Penning, Biochemistry 1991, 30, 11553.
- (1991) Biochemistry , vol.30 , pp. 11553
- Askonas, L.J.¹ Penning, T.M.²

35
- 3943106081
- L. R. Pottier, J.-F. Peyrat, M. Alami, J.-D. Brion, Synlett 2004, 9, 1503.
- (2004) Synlett , vol.9 , pp. 1503
- Pottier, L.R.¹ Peyrat, J.-F.² Alami, M.³ Brion, J.-D.⁴

36
- 0042159883
- L. M. Antunes, M. G. Organ, Tetrahedron Lett. 2003, 44, 6805.
- (2003) Tetrahedron Lett. , vol.44 , pp. 6805
- Antunes, L.M.¹ Organ, M.G.²

37
- 84983723704
- A. Venturini Moro, C. W. Nogueira, N. B. V. Barbosa, P. H. Menezes, J. B. T. da Rocha, G. Zeni, J. Org. Chem. 2005, 70, 5257.
- (2005) J. Org. Chem. , vol.70 , pp. 5257
- Venturini Moro, A.¹ Nogueira, C.W.² Barbosa, N.B.V.³ Menezes, P.H.⁴ Da Rocha, J.B.T.⁵ Zeni, G.⁶

38
- 1342303394
- V. P. Ananikov, I. P. Beletskaya, Org. Biomol. Chem. 2004, 2, 284.
- (2004) Org. Biomol. Chem. , vol.2 , pp. 284
- Ananikov, V.P.¹ Beletskaya, I.P.²

39
- 8744304751
- A. K. Feldman, B. Colasson, V. V. Fokin, Org. Lett. 2004, 6, 3897.
- (2004) Org. Lett. , vol.6 , pp. 3897
- Feldman, A.K.¹ Colasson, B.² Fokin, V.V.³

40
- 0037099395
- V. V. Rostovtsev, L. G. Grenn, V. V. Fokin, K. B. A. Sharpless, Angew. Chem., Int. Ed. 2002, 41, 2596.
- (2002) Angew. Chem., Int. Ed. , vol.41 , pp. 2596
- Rostovtsev, V.V.¹ Grenn, L.G.² Fokin, V.V.³ Sharpless, K.B.A.⁴

41
- 33947526772
- P. Wu, V. V. Fokin, Aldrichimica Acta 2007, 40, 7.
- (2007) Aldrichimica Acta , vol.40 , pp. 7
- Wu, P.¹ Fokin, V.V.²

42
- 33846703461
- W. H. Binder, R. Sachsenhofer, Macromol. Rapid Commun. 2007, 28, 15.
- (2007) Macromol. Rapid Commun. , vol.28 , pp. 15
- Binder, W.H.¹ Sachsenhofer, R.²

43
- 0345283269
- M. Tourirte, T. Oulih, H. B. Lazrek, J. L. Barascut, J. L. Imbach, N. A. Almasoudi, Nucleosides, Nucleotides Nucleic Acids 2003, 22, 1985.
- (2003) Nucleosides, Nucleotides Nucleic Acids , vol.22 , pp. 1985
- Tourirte, M.¹ Oulih, T.² Lazrek, H.B.³ Barascut, J.L.⁴ Imbach, J.L.⁵ Almasoudi, N.A.⁶

44
- 28544446290
- L. Zhou, A. Amer, M. Korn, R. Burda, J. Balzarini, E, De Clercq, E. R. Kern, P. F. Torrence, Antiviral Chem. Chemother. 2005, 16, 375.
- (2005) Antiviral Chem. Chemother. , vol.16 , pp. 375
- Zhou, L.¹ Amer, A.² Korn, M.³ Burda, R.⁴ Balzarini, J.⁵ De Clercq, E.⁶ Kern, E.R.⁷ Torrence, P.F.⁸

45
- 0034742984
- M. Armengol, J. A. Joule, J. Chem. Soc., Perkin Trans. 1 2001, 978.
- (2001) J. Chem. Soc., Perkin Trans. 1 , pp. 978
- Armengol, M.¹ Joule, J.A.²

46
- 0032912202
- R. Bianchini, C. Chiappe, G. Lo Moro, D. Lenoir, P. Lemmen, N. Goldberg, Chem.-Eur. J. 1999, 5, 1570.
- (1999) Chem.-Eur. J. , vol.5 , pp. 1570
- Bianchini, R.¹ Chiappe, C.² Lo Moro, G.³ Lenoir, D.⁴ Lemmen, P.⁵ Goldberg, N.⁶

47
- 0029976422
- A. L. Hopkins, J. Ren, R. M. Esnouf, B. E. Willcox, E. Y. Jones, C. Ross, T. Miyasaka, R. T. Walker, H. Tanaka, D. K. Stammers, D. I. Stuart, J. Med. Chem. 1996, 39, 1589.
- (1996) J. Med. Chem. , vol.39 , pp. 1589
- Hopkins, A.L.¹ Ren, J.² Esnouf, R.M.³ Willcox, B.E.⁴ Jones, E.Y.⁵ Ross, C.⁶ Miyasaka, T.⁷ Walker, R.T.⁸ Tanaka, H.⁹ Stammers, D.K.¹⁰ Stuart, D.I.¹¹

48
- 0033546262
- M. Frigerio, M. Santagostino, S. Sputore, J. Org. Chem. 1999, 64, 4537.
- (1999) J. Org. Chem. , vol.64 , pp. 4537
- Frigerio, M.¹ Santagostino, M.² Sputore, S.³

49
- 0000234498
- J. D. More, N. S. Finney, Org. Lett. 2002, 17, 3001.
- (2002) Org. Lett. , vol.17 , pp. 3001
- More, J.D.¹ Finney, N.S.²

50
- 33747140370
- R. Pauwels, Antiviral Res. 2006, 71, 77.
- (2006) Antiviral Res. , vol.71 , pp. 77
- Pauwels, R.¹

51
- 0026543676
- H. Tanaka, H. Takashima, M. Ubasawa, K. Sekiya, I. Nitta, M. Baba, S. Shigeta, R. T. Walker, E. De Clercq, T. Miyasaka, J. Med. Chem. 1992, 35, 337.
- (1992) J. Med. Chem. , vol.35 , pp. 337
- Tanaka, H.¹ Takashima, H.² Ubasawa, M.³ Sekiya, K.⁴ Nitta, I.⁵ Baba, M.⁶ Shigeta, S.⁷ Walker, R.T.⁸ De Clercq, E.⁹ Miyasaka, T.¹⁰

52
- 0035324943
- S. Hannongbua, K. Nivesanond, L. Lawtrakul, P. Pungpo, P. Wolschann, J. Chem. Inf. Comput. Sci. 2001, 41, 848.
- (2001) J. Chem. Inf. Comput. Sci. , vol.41 , pp. 848
- Hannongbua, S.¹ Nivesanond, K.² Lawtrakul, L.³ Pungpo, P.⁴ Wolschann, P.⁵

53
- 27744502081
- A. Bak, J. Polanski, Bioorg. Med. Chem. 2006, 14, 273.
- (2006) Bioorg. Med. Chem. , vol.14 , pp. 273
- Bak, A.¹ Polanski, J.²

54
- 34247611805
- M. Radi, A. D. Adema, J. R. Daft, J. H. Cho, E. K. Hoebe, L.-E. M. M. Alexander, G. J. Peters, C. K. Chu, J. Med. Chem. 2007, 50, 2249.
- (2007) J. Med. Chem. , vol.50 , pp. 2249
- Radi, M.¹ Adema, A.D.² Daft, J.R.³ Cho, J.H.⁴ Hoebe, E.K.⁵ Alexander, L.-E.M.M.⁶ Peters, G.J.⁷ Chu, C.K.⁸

55
- 1342343124
- M. Wamberg, E. B. Pedersen, N. R. El-Brollosy, C. Nielsen, Bioorg. Med. Chem. 2004, 12, 1141.
- (2004) Bioorg. Med. Chem. , vol.12 , pp. 1141
- Wamberg, M.¹ Pedersen, E.B.² El-Brollosy, N.R.³ Nielsen, C.⁴

56
- 0038548447
- H. Jian, J. M. Tour, J. Org. Chem. 2003, 68, 5091.
- (2003) J. Org. Chem. , vol.68 , pp. 5091
- Jian, H.¹ Tour, J.M.²

57
- 67749139545
- U.S. Pat. 20070043028
- S.-T. Jan, K.-J. Chang, K. P. Biciunas, X. Ma, U.S. Pat. 20070043028, 2007, p. 9-10.
- (2007) , pp. 9-10
- Jan, S.-T.¹ Chang, K.-J.² Biciunas, K.P.³ Ma, X.⁴

58
- 0037432457
- H. Doi, M. Kinoshita, K. Okumoto, Y. Shirota, Chem. Mater. 2003, 15, 1080.
- (2003) Chem. Mater. , vol.15 , pp. 1080
- Doi, H.¹ Kinoshita, M.² Okumoto, K.³ Shirota, Y.⁴

59
- 0013891645
- G. Shtacher, W. Taub, J. Med. Chem. 1966, 9, 197.
- (1966) J. Med. Chem. , vol.9 , pp. 197
- Shtacher, G.¹ Taub, W.²

60
- 67749101837
- Ph.D. Thesis, The Jagiellonian University, Cracow
- K. Danel, Ph.D. Thesis, The Jagiellonian University, Cracow, 1998.
- (1998)
- Danel, K.¹

61
- 0023687234
- R. Pauwels, J. Balzarini, M. Baba, R. Snoeck, D. Schols, P. Herdewijn, J. Desmyter, E. De Clercq, J. Virol. Methods 1988, 20, 309.
- (1988) J. Virol. Methods , vol.20 , pp. 309
- Pauwels, R.¹ Balzarini, J.² Baba, M.³ Snoeck, R.⁴ Schols, D.⁵ Herdewijn, P.⁶ Desmyter, J.⁷ De Clercq, E.⁸

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