New methodology for 2-alkylation of 3-furoic acids: Application to the synthesis of tethered UC-781/d4T bifunctional HIV reverse-transcriptase inhibitors

Tetrahedron Letters

Volumn 46, Issue 23, 2005, Pages 4023-4026

  Arnott, Gareth ^a   Hunter, Roger ^a   Mbeki, Linda ^a   Mohamed, Ebrahim ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Alkylated UC 781; Bifunctional HIV reverse transcriptase inhibitors; Furan alkylation; Wittig reaction of 2 furanylphosphonium salt

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; FURAN DERIVATIVE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE PLUS STAVUDINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CONJUGATE; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS; TECHNIQUE; WITTIG REACTION;

EID: 18844401130     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.04.034     Document Type: Article

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