Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a Nanopore

Journal of the American Chemical Society

Volumn 131, Issue 10, 2009, Pages 3772-3778

  Hurt, Nicholas ^a   Wang, Hongyun ^b   Akeson, Mark ^b   Lieberman, Kate R ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California Santa Cruz   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APPLIED ELECTRIC FIELD; AVERAGE DWELL TIME; CATALYTIC ACTIVITY; CONCENTRATION OF; DNA COMPLEX; DNA POLYMERASE; DNA SYNTHESISS; DWELL TIME; EQUILIBRIUM DISSOCIATION CONSTANT; KLENOW FRAGMENT; LINEAR REGIME; LINEAR RELATIONSHIPS; NANO-SCALE PORES; NUCLEOTIDE BINDING; ORDERS OF MAGNITUDE; REAL TIME; RNA PROCESSING; SINGLE-MOLECULE ANALYSIS; TRIPHOSPHATE; TWO-REGIME; TWO-STATE MODEL;

CATALYSTS; CONCENTRATION (PROCESS); DISSOCIATION; DNA; ELECTRIC FIELDS; ENZYMES; ESCHERICHIA COLI; GENES; NANOPORES; RNA; TIME MEASUREMENT; TITRATION;

NUCLEIC ACIDS;

ALPHA HEMOLYSIN; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; NUCLEOTIDE; DEOXYGUANOSINE PHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; PROTEIN BINDING;

ARTICLE; CATALYSIS; DNA BINDING; DNA SEQUENCE; DNA SYNTHESIS; ESCHERICHIA COLI; NANOPORE; DNA REPLICATION; ENZYMOLOGY; METABOLISM;

DEOXYGUANINE NUCLEOTIDES; DNA POLYMERASE I; DNA REPLICATION; ESCHERICHIA COLI; NUCLEOTIDES; PROTEIN BINDING;

EID: 67749111706     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja809663f     Document Type: Article

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