Identification of potential cellular targets of aloisine A by affinity chromatography

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 15, 2009, Pages 5572-5582

  Corbel, Caroline ^a   Haddoub, Rose ^b   Guiffant, Damien ^a   Lozach, Olivier ^a   Gueyrard, David ^b   Lemoine, Jérôme ^c   Ratin, Morgane ^a   Meijer, Laurent ^a   Bach, Stéphane ^a   Goekjian, Peter ^b  

^a Protein Phosphorylation and Human Disease Group   (France)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

Affinity chromatography; Aloisine; Click chemistry; Cyclin dependent kinase; ERK1; Fuse binding protein 1; Glycogen debranching enzyme; GSK 3; Immobilized protein kinase inhibitor; Mass spectrometry; Pyridoxal kinase; Pyrrolo 2,3 b pyrazine

Indexed keywords

ALOISINE A; PYRAZINE DERIVATIVE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; NONHUMAN;

ANIMALS; BRAIN; CHROMATOGRAPHY, AFFINITY; CYCLIN-DEPENDENT KINASES; GLYCOGEN SYNTHASE KINASE 3; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PYRAZINES; PYRROLES; SACCHAROMYCES CEREVISIAE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SWINE;

EID: 67749110088     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.06.024     Document Type: Article

References (46)

1. Dhavan R., and Tsai L.H. Nat. Rev. Mol. Cell Biol. 2 (2001) 749
2. Malumbres M., Ortega S., and Barbacid M. Biol. Chem. 381 (2000) 827
3. Morgan D.O. Annu. Rev. Cell Dev. Biol. 13 (1997) 261
4. Knockaert M., Greengard P., and Meijer L. Trends Pharmacol. Sci. 23 (2002) 417
5. Mazanetz M.P., and Fischer P.M. Nat. Rev. Drug Discovery 6 (2007) 464
6. Cohen P. Nat. Rev. Drug Discovery 1 (2002) 309
7. Fischer P.M., and Lane D.P. Curr. Med. Chem. 7 (2000) 1213
8. Gray N., Detivaud L., Doerig C., and Meijer L. Curr. Med. Chem. 6 (1999) 859
9. Davies S.P., Reddy H., Caivano M., and Cohen P. Biochem. J. 351 (2000) 95
10. Bach S., Blondel M., and Meijer L. Monographs on Enzyme Inhibitors Vol. 2 (2006), CRC Press, Boca Raton, FL 103
11. Terstappen G.C., Schlupen C., Raggiaschi R., and Gaviraghi G. Nat. Rev. Drug Discovery 6 (2007) 891
12. Guiffant D., Tribouillard D., Gug F., Galons H., Meijer L., Blondel M., and Bach S. Biotechnol. J. 2 (2007) 68
13. Knockaert M., Gray N., Damiens E., Chang Y.T., Grellier P., Grant K., Fergusson D., Mottram J., Soete M., Dubremetz J.F., Le Roch K., Doerig C., Schultz P., and Meijer L. Chem. Biol. 7 (2000) 411
14. Knockaert M., Wieking K., Schmitt S., Leost M., Grant K.M., Mottram J.C., Kunick C., and Meijer L. J. Biol. Chem. 277 (2002) 25493
15. Wan Y., Hur W., Cho C.Y., Liu Y., Adrian F.J., Lozach O., Bach S., Mayer T., Fabbro D., Meijer L., and Gray N.S. Chem. Biol. 11 (2004) 247
16. Brehmer D., Greff Z., Godl K., Blencke S., Kurtenbach A., Weber M., Muller S., Klebl B., Cotten M., Keri G., Wissing J., and Daub H. Cancer Res. 65 (2005) 379
17. Bach S., Knockaert M., Reinhardt J., Lozach O., Schmitt S., Baratte B., Koken M., Coburn S.P., Tang L., Jiang T., Liang D.C., Galons H., Dierick J.F., Pinna L.A., Meggio F., Totzke F., Schachtele C., Lerman A.S., Carnero A., Wan Y., Gray N., and Meijer L. J. Biol. Chem. 280 (2005) 31208
18. Mettey Y., Gompel M., Thomas V., Garnier M., Leost M., Ceballos-Picot I., Noble M., Endicott J., Vierfond J.M., and Meijer L. J. Med. Chem. 46 (2003) 222
19. Mapelli M., Massimiliano L., Crovace C., Seeliger M.A., Tsai L.H., Meijer L., and Musacchio A. J. Med. Chem. 48 (2005) 671
20. Vierfond J.M., Mettey Y., Mascrier-Demagny L., and Miocque M. Tetrahedron Lett. 22 (1981) 1219
21. Davis M., Wakefield B., and Wardell J. Tetrahedron 48 (1992) 939
22. Fuchter M., Beall L., Baum S., Montalban A., Sakellariou E., Mani N., Miller T., Vesper B., White A., Williams D., Barrett A., and Hoffman B. Tetrahedron 61 (2005) 6115
23. Eduardo F.M., Correa J., Irene R.M., and Ricardo R. Macromolecules 39 (2006) 2113
24. Haddoub R., Gueyrard D., and Goekjian P. Tetrahedron Lett. 50 (2009) 741
25. Traxler P., and Furet P. Pharmacol. Therapeut. 82 (1999) 195
26. Mukai F., Ishiguro K., Sano Y., and Fujita S.C. J. Neurochem. 81 (2002) 1073
27. Fischer P.M. Chem. Biol. 10 (2003) 1144
28. Meijer L., Skaltsounis A.L., Magiatis P., Polychronopoulos P., Knockaert M., Leost M., Ryan X.P., Vonica C.A., Brivanlou A., Dajani R., Crovace C., Tarricone C., Musacchio A., Roe S.M., Pearl L., and Greengard P. Chem. Biol. 10 (2003) 1255
29. Watanabe Y., Makino Y., and Omichi K. J. Biochem. 143 (2008) 435
30. Araujo W.L., Nunes-Nesi A., Trenkamp S., Bunik V.I., and Fernie A.R. Plant Physiol. 148 (2008) 1782
31. Lukacs C.M., Oikonomakos N.G., Crowther R.L., Hong L.-N., Kammlott R.U., Levin W., Li S., Liu C.M., McGady D.L., Pietranico S., and Reik L. Proteins: Structure, Function and Bioinformatics 63 (2006) 1123
32. Chung H.J., Liu J., Dundr M., Nie Z., Sanford S., and Levens D. Mol. Cell. Biol. 26 (2006) 6584
33. Berlicki L. Mini.-Rev. Med. Chem. 8 (2008) 869
34. Reprocessing of the data with a recent version of the database led to the possible identification of MEK-1 (Table S2 of the Supplementary data). However, Mettey et al. have shown previously that this kinase is not a target of aloisine (Ref. 18).
35. Wu D., Dou X., Hashmi S.B., and Osmani S.A. J. Biol. Chem. 279 (2004) 37693
36. Huang D., Patrick G., Moffat J., Tsai L.H., and Andrews B. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 14445
37. Huang D., Friesen H., and Andrews B. Mol. Microbiol. 66 (2007) 303
38. Ceccarelli E., and Mann C. J. Biol. Chem. 276 (2001) 41725
39. Kung C., Kenski D.M., Krukenberg K., Madhani H.D., and Shokat K.M. Chem. Biol. 13 (2006) 399
40. Doerig C., Meijer L., and Mottram J.C. Trends Parasitol. 18 (2002) 366
41. Droucheau E., Primot A., Thomas V., Mattei D., Knockaert M., Richardson C., Sallicandro P., Alano P., Jafarshad A., Baratte B., Kunick C., Parzy D., Pearl L., Doerig C., and Meijer L. Biochim. Biophys. Acta 1697 (2004) 181
42. Tang L., Li M.H., Cao P., Wang F., Chang W.R., Bach S., Reinhardt J., Ferandin Y., Galons H., Wan Y., Gray N., Meijer L., Jiang T., and Liang D.C. J. Biol. Chem. 280 (2005) 31220
43. Meijer L., and Raymond E. Acc. Chem. Res. 36 (2003) 417
44. Godl K., Wissing J., Kurtenbach A., Habenberger P., Blencke S., Gutbrod H., Salassidis K., Stein-Gerlach M., Missio A., Cotten M., and Daub H. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 15434
45. Brehmer D., Godl K., Zech B., Wissing J., and Daub H. Mol. Cell. Proteomics 3 (2004) 490
46. Trapp J., Jochum A., Meier R., Saunders L., Marshall B., Kunick C., Verdin E., Goekjian P., Sippl W., and Jung M. J. Med. Chem. 49 (2006) 7307