Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives

Journal of Biological Chemistry

Volumn 280, Issue 35, 2005, Pages 31220-31229

  Tang, Lin ^a,e   Li, Ming Hui ^a   Cao, Peng ^a,e   Wang, Feng ^a,e   Chang, Wen Rui ^a   Bach, Stéphane ^b   Reinhardt, Jens ^b   Ferandin, Yoan ^b   Galons, Hervé ^c   Wan, Yoagqin ^d   Gray, Nathanael ^d   Meijer, Laurent ^b   Jiang, Tao ^a   Liang, Dong Cai ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b STATION BIOLOGIQUE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOCHEMISTRY; DERIVATIVES; STRUCTURAL ANALYSIS;

PYRIDOXAL 5′-PHOSPHATE (PLP); PYRIDOXAL KINASE (PDXK); STRUCTURAL INFORMATION;

CRYSTAL STRUCTURE;

6 N METHYLROSCOVITINE; 6 O ROSCOVITINE; ADENOSINE TRIPHOSPHATE; CYCLIN DEPENDENT KINASE INHIBITOR; PYRIDOXAL; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAL KINASE; PYRIDOXAMINE; PYRIDOXINE; ROSCOVITINE; ROSCOVITINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING SITE; CANCER; CATALYSIS; CRYSTAL STRUCTURE; DEGENERATIVE DISEASE; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; KIDNEY DISEASE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; STRUCTURE ANALYSIS; VIRUS INFECTION;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PURINES; PYRIDOXAL KINASE; SWINE;

EID: 24744461692     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500805200     Document Type: Article

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