Can Drosophila melanogaster represent a model system for the detection of reproductive adverse drug reactions?

Drug Discovery Today

Volumn 14, Issue 15-16, 2009, Pages 761-766

  Avanesian, Agnesa ^a   Semnani, Sahar ^a   Jafari, Mahtab ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE; RNA; SEX HORMONE; STEROIDOGENIC FACTOR 1;

ALTERNATIVE RNA SPLICING; COST EFFECTIVENESS ANALYSIS; DISEASE MODEL; DROSOPHILA MELANOGASTER; DRUG RESEARCH; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; EGG PRODUCTION; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HORMONE ACTION; HUMAN; MAMMAL; MOLECULAR MECHANICS; NONHUMAN; PROTEIN FUNCTION; REPRODUCTIVE TOXICITY; REVIEW; SEX DIFFERENTIATION; SPECIES DIFFERENCE; TERATOGENESIS; VALIDATION PROCESS;

ANIMALS; COST-BENEFIT ANALYSIS; DROSOPHILA MELANOGASTER; DRUG DESIGN; FEMALE; HUMANS; MALE; METHOTREXATE; MODELS, ANIMAL; PHARMACEUTICAL PREPARATIONS; REPRODUCTION; SPECIES SPECIFICITY;

EID: 67651222112     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2009.05.010     Document Type: Review

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