Identification of a novel Drosophila gene, beltless, using injectable embryonic and adult RNA interference (RNAi)

BMC Genomics

Volumn 4, Issue , 2003, Pages

  Dzitoyeva, Svetlana ^a   Dimitrijevic, Nikola ^a   Manev, Hari ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; DOUBLE STRANDED RNA; MESSENGER RNA; BELTLESS PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; SMALL INTERFERING RNA;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; DROSOPHILA; EMBRYO; GENE ACTIVITY; GENE DELETION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE INDUCTION; GENOMICS; INSECT DEVELOPMENT; NERVOUS SYSTEM; NONHUMAN; OVARY; PHENOTYPE; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY; SPINAL CORD; AMINO ACID SEQUENCE; ANIMAL; ANIMAL EMBRYO; DROSOPHILA MELANOGASTER; FEMALE; GENE; GENE STRUCTURE; GENETICS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; INJECTION; MALE; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; PRENATAL DEVELOPMENT;

DROSOPHILA MELANOGASTER; MELANOGASTER;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; FEMALE; GENE COMPONENTS; GENES, INSECT; INJECTIONS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 9444254045     PISSN: 14712164     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2164-4-33     Document Type: Article

References (36)

1. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE and Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
2. Carthew RW: Gene silencing by double-stranded RNA. Curr Opin Cell Biol 2001, 13:244-248.
3. Smalheiser NR, Manev H and Costa E: RNAi and brain function: was McConnell on the right track b? Trends Neurosci 2001, 24:216-218.
4. Schmid A, Schindelholz B and Zinn K: Combinatorial RNAi: a method for evaluating the functions of gene families in Drosophila. Trends Neurosci 2002, 25:71-74.
5. Shi Y: Mammalian RNAi for the masses. Trends Genet 2003, 19:9-12.
6. Dzitoyeva S, Dimitrijevic N and Manev H: Intra-abdominal injection of double-stranded RNA into anesthetized adult Drosophila triggers RNA interference in the central nervous system. Mol Psychiatry 2001, 6:665-670.
7. Dzitoyeva S, Dimitrijevic N and Manev H: γ-Aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence. Proc Natl Acad Sci USA 2003, 100:5485-5490.
8. Manev H, Dimitrijevic N and Dzitoyeva S: Fruit flies as models for neuropharmacological research. Trends Pharmacol Sci 2003, 24:41-43.
9. Amdam GV, Simones ZL, Guidugli KR, Norberg K and Omholt SW: Disruption of vitellogenin gene function in adult honeybees by intra-abdominal injection of double-stranded RNA. BMC Biotechnol 2003, 3:1.
10. Korneev SA, Kemenes I, Straub V, Staras K, Korneeva EI, Kemenes G, Benjamin PR and O'Shea M: Suppression of nitric oxide (NO)-dependent behavior by double-stranded RNA-mediated silencing of a neuronal NO synthase gene. J Neurosci 2002, 22:RC227.
11. Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P and Lieberman J: RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003, 9:347-351.
12. Chen M-J and Lai Y-L: Tachykinin dysfunction attenuates monocrotaline-induced pulmonary hypertension. Toxicol Appl Pharmacol 2003, 187:178-185.
13. Roignat J-Y, Carre C, Mugat B, Szymczak D, Lepesant J-A and Antoniewski C: Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. RNA 2003, 9:299-308.
14. Van Roessel P, Hayward NM, Barros CS and Brand AH: Two-color GFP imaging demonstrates cell-autonomy of GAL4-driven RNA interference in Drosophila. Genesis 2002, 34:170-173.
15. Choy RK and Thomas JH: Fluoxetine-resistant mutants in C. elegans define a novel family of transmembrane proteins. Mol Cell 1999, 4:143-152.
16. Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB and Blakely RD: High affinity recognition of serotonin transporter antagonists defined by species-scenning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol. J Biol Chem 1998, 273:19459-19468.
17. Dzitoyeva S, Dimitrijevic N and Manev H: Drosophila as a model for discovering novel therapeutic gene targets. Biol Psychiatry 2002, 51:135S.
18. Bourbon HM, Gonzy-Treboul G, Peronnet F, Alin MF, Ardourel C, Benassayag C, Cribbs D, Deutsch J, Ferrer P, Haenlin M, Lepesant JA, Noselli S and Vincent A: A P-insertion screen identifying novel X-linked essential genes in Drosophila. Mech Dev 2002, 110: 1-83.
19. Falquet L, Pagni M, Bucher P, Hulo N, Sigrist CJ, Hofmann K and Bairoch A: The PROSITE database, its status in 2002. Nucleic Acids Res 2002, 30:235-238.
20. Hofmann K, Bucher P, Falquet L and Bairoch A: The PROSITE database, its status in 1999. Nucleic Acids Res 1999, 27: 15-219.
21. Alexandre C, Lecourtois M and Vincent J-P: Wingless and Hedgehog pattern Drosophila denticle belts by regulating the production of short-range signals. Development 1999, 126:5689-5698.
22. Wiellette EL and McGinnis W: Hox genes differentially regulate Serrate to generate segment-specific structures. Development 1999, 126:1985-1995.
23. Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ and Beachy PA: The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 1995, 374:363-366.
24. Porter JA, Young KE and Beachy PA: Cholesterol modification of hedgehog signaling proteins in animal development. Science 1996, 274:255-259.
25. Chamoun Z, Mann RK, Nellen D, von Kessler DP, Bellotto M, Beachy PA and Basler K: Skinny Hedgehog, an Acyltransferase required for Palmitoylation and Activity of the Hedgehog Signal. Science 2001, 293:2080-2083.
26. Micchelli CA, The I, Selva E, Mogila V and Perrimon N: Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling. Development 2002, 129:843-851.
27. Suzuki Y, Shimozawa N, Imamura A, Fukuda S, Zhang Z, Orii T and Kondo N: Clinical, biochemical and genetic aspects and neuronal migration in peroxisome biogenesis disorders. J Inherit Metab Dis 2001, 24:151-165.
28. Subramani S, Koller A and Snyder WB: Import of peroxisomal matrix and membrane proteins. Annu Rev Biochem 2000, 69: 99-418.
29. Singh I, Carillo O and Namboodiri A: Isolation and biochemical characterization of peroxisomes from cultured rat glial cells. Neurochem Res 2000, 25:197-203.
30. Megias A, Municio AM and Perez-Albarsanz MA: Biochemistry of development in insects. Triacylglycerol and phosphoglyceride biosynthesys by subcellular fractions. Eur J Biochem 1977, 72:9-16.
31. Guichet A, Wucherpfenning T, Dudu V, Etter S, Wilsch-Brauninger M, Hellwig A, Gonzales-Gaitan M, Huttner WB and Schmidt AA: Essential role of endophilin A in synaptic vesicle budding at the Drosophila neuromuscular junction. EMBO J 2002, 21: 661-1672.
32. Hannah MJ, Schmidt AA and Huttner WB: Synaptic vesicle biogenesis. Annu Rev Cell Dev Biol 1999, 15:733-798.
33. Kuhl D and Skehel P: Dendritic localization of mRNAs. Curr Opin Neurobiol 1998, 8:600-606.
34. Whiting P and Dinan L: Formation of apolar ecdysteroid conjugates by ovaries of the house cricket Acheta domesticus in vitro. Biochem J 1988, 15:95-103.
35. Sambrook J and Russel DW: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, Cold Spring Harbor 2001.
36. Sullivian W, Ashburner R and Hawley S: Drosophila Protocols. Cold Spring Harbor: Cold Spring Harbor Laboratory Press 2000.