The pharmacology of ageing in drosophila

Current Drug Targets

Volumn 7, Issue 11, 2006, Pages 1479-1483

  Jafari, Mahtab ^a   Long, Anthony D ^b   Mueller, Laurence D ^b   Rose, Michael R ^b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging pathways; Anti aging; Drosophila; Drug testing; Lifespan; Pharmaceuticals

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ARYLBUTYRIC ACID DERIVATIVE; CYTOCHROME P450 3A4; ETHOSUXIMIDE; EUKARIAN 134; EUKARIAN 8; GINKGO BILOBA EXTRACT; HUMAN GROWTH HORMONE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; RESVERATROL; SUPEROXIDE DISMUTASE; THIOCTIC ACID; TRIMETHADIONE; UNCLASSIFIED DRUG;

AGING; CITRIC ACID CYCLE; DNA REPAIR; DOSE RESPONSE; DROSOPHILA; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; ENZYMATIC ASSAY; FOOD INTAKE; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; INSECT CELL CULTURE; LIFESPAN; LONGEVITY; MASS SPECTROMETRY; NATURAL SELECTION; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PROTEIN MICROARRAY; REVIEW; SYSTEMATIC REVIEW;

EID: 33750865187     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450110607011479     Document Type: Review

References (53)

1. Pletcher, S.D., Macdonald, S.J., Margueri, R., Certa, U., Stearns, S.C., Goldstein, D.B., Partridge, L. (2002) Curr. Biol., 12, 712-723.
2. Rose, M.R., Long, D.A. (2002) Curr. Biol., 12 (9), R311-R312.
3. Fleming, J.E., Spicer G.S., Garrison R.C., Rose M.R. (1993). Genetica, 91, 183-198.
4. Maynard Smith, J. (1959) J. Genet., 56,1-9.
5. Lin, Y.J., Seroud, L., Benzer, S. (1998) Science, 282,943-946.
6. Rogina, B., Reenan, R.B., Nilsen, S.P., Helfand, S.L. (2000) Science, 290, 2137-2140.
7. Marden, J.H., Rogina, B., Montooth, K.L., Helfand, S.L. Proc. Natl. Acad. Sci. USA, 100(6), 3369-3373.
8. Tatar, M., Kopelman, A., Epstein, D., Tu, M-P., Yin, C-M., Garofalo, R.S (2001) Science, 292, 107-109.
9. Rose, M.R (1991) Evolutionary Biology of Aging, Oxford University Press, New York.
10. Rose, M.R (1984) Evolution, 38(5), 1004-1010.
11. Luckinbill, L.S., Arking, R., Clare, M.J., Cirocco, W.C., Buck, S.A (1984) Evolution, 38,996-1003.
12. Rose, M.R., Passananti, H.B., Matos, M (2004) Methuselah Flies: A Cse Study in the Evolution of Aging, World Scientific Publishing Co. Pte, Ltd, Singapore.
13. Van Voorhies, W.A., Ward, S (1999) Proc. Natl. Acad. Sci. USA, 96(11), 399-403.
14. Djawdan, M., Sugiyama, T., Schlaeger L., Bradley T.J., Rose M.R (1996) Physiol. Zool., 69, 1175-1195.
15. Lints, F.A., Soliman, M.H (1988) Drosophila as a model Organism for Aging Studies, Blackie and Son Ltd, London, pp. 17-27.
16. Loeb, J., Northrup, J.H. (1916) Proc. Natl. Acad. Sci. USA, 2, 456-57.
17. Loeb, J., Northrup, J.H. (1917) J. Biol. Chem., 32, 103-121.
18. Miquel, J., Lundgren, P.R., Bensch, K.G., Atlan, H. (1976) Mech. Ageing Dev., 5,347-370.
19. Chippindale, A.K., Leroi, A. M., Saing, H., Borash, D.J., Rose, M.R. (1997) J. Evolutionary Biol., 10, 269-293.
20. Charlesworth, B., Partridge, L. (1997) Curr. Biol., 7,R440-R442.
21. Rose, M., Charlesworth, B. (1980) Nature, 287,141-142.
22. Curtsinger, J. W., Fukui, H. H., Townsend, D. R., Vaupel, J. W. (1992). Science, 258, 461-463.
23. Rose, M. R, Drapeau, M. D., Yazdi, P. G., Shah, K. H., Moise, D. B., Thakar, R. R., Rauser, C. L., Mueller, L. D. (2002) Evolution, 56,1982-1991.
24. Mueller, L.D., Nusbaum, T.J., Rose, M.R. (1995) Exp. Gerontol., 30,553-569.
25. Nusbaum, T. J., Mueller, L.D., Rose, M.R. (1996) Exp. Gerontol., 31, 507-516.
26. Lints, F.A., Soliman, M.H. (1988) Drosophila as a model Organism for Aging Studies, Blackie and Son Ltd, London, pp. 59-70
27. Rose, M.R., Passananti, H.B., Mato, M (2004) Methuselah Flies A Case Study in the Evolution of Aging. World Scientific Publishing, Singapore.
28. Burnet, B., Sewell, D., Bos, M (1977) Genet. Res., 30, 149-61.
29. Joshi, A., Mueller, L.D. (1988) Evolution, 42,1090-1093.
30. Santos, M., Borash, D.J., Joshi, A., Bounlutay, N., Mueller, L.D (1997) Evolution, 51, 420-432.
31. Mueller, L.D., Folk, D.G., Nguyen, N., Nguyen, P., Lam, P., Rose, M.R., Bradley, T. (in press) Physiol. Entomol.
32. Feyereisen, R. (1999) Ann. Rev. Entomol., 44, 507-533.
33. Dzitoyeva, S., Dimitrijevic, N., Manev, H. (2003) Proc. Natl. Acad. Sci. USA, 100(9), 5485-5490.
34. Danielson, P.B., Foster, J.L.M, McMahill, M.M., Smith, M.K., Fogleman, J.C. (1998) Mol. Gen. Genet., 259, 54-59.
35. Johns Cupp, M., Tracy, T.S. (1998) Am. Fam. Physician 57(1), 107-115.
36. Wood, J.G., Rogina, B., Lavu, S., Howitz, K., Helfand, S.L., Tatar, M., Sinclair, D. (2004) Nature, 430, 686-689.
37. Kang, H.L., Benzer, S., Min, K.T. (2002) Proc. Natl. Acad. Sci. USA, 99(2), 838-843.
38. Bauer, H. J., Goupil, S., Garber, B., Helfand, S.L. (2004) Proc. Natl. Acad. Sci. USA, 101(35), 12980-12985.
39. Melov, S., Ravenscroft, J., Malik, S., Gill, M.S., Walker, D.W., Clayton, P.E., Wallace, D.C., Malfroy, B., Doctrow, S.R., Lithgow, G.J. (2000) Science, 289,1567-1569.
40. Melov, S., Doctrow, S.R., Schneider, J.A., Haberson, J., Patel, M., Coskun, P.E., Huffman, K., Wallace, D.C., Malfroy, B. (2001) J. Neurosci., 21(21), 8348-8353.
41. Evason, K., Huang, C., Yamben, I., Covey, D.F., Kornfeld, K. (2005) Science, 307, 258-262.
42. Driver, C., Geiorgeou, A. (2003) Biogerontology, 4, 91-95.
43. Lonn, E., Yusuf, S., Hoogwerf, B., Pogue, J., Yi, Q., Zinman, B., Bosch, J., Dagenais, G., Man, J., Gerstein, H.C. (2002) Diabetes Care, 25(11), 1919-1927.
44. Shekelle, P.G., Morton, S.C., Jungvig, L.K., Udani, J., Spar, M., Tu, W. (2004) J. Gen. Internal Med., 19(4), 380-389.
45. Miller, E.R., Pastor-Barriuso, R., Dalal, D., Riemersma, R.A., Appel, L.J., Guallar, E. (2005) Am. Coll. Physicians 142, 37-46
46. Kaeberlein, M., McDonagh, T., Heltweg, B., Hixon, J., Westman, E.A., Caldwell, S.D., Napper, A., Curtis, R., DiStefano, P.S., Fields, S., Bedalov, A., Kennedy, B.K. (2005) J. Biol. Chem., 31, 2005.
47. Picard, F., Guarente, L. (2005) Int. J. Obesity, 29, S36-S39.
48. Buhler, M., Kahn, B.B., Kahn, C.R. (2003) Science, 299, 572-574.
49. Missirlis, F., Phillips, J.P., Jackle, H. (2001) Curr. Biol., 11, 1272-1277.
50. Landis, G.N., Tower, J. (2005) Mechanism Aging Develop., 126, 365-379.
51. Parkes, T.L., Elia, A.J., Dickinson, D., Hilliker, A.J., Phillips, J.P., Boulianne, G.L. (1998) Nature, 19, 171-174.
52. Guarante, L., Kenyon, C. (2000) Nature, 408(6809), 255-262.
53. Johnson T.E. (2001) Gerontologist, 41, 2-2sp.