메뉴 건너뛰기




Volumn 29, Issue 15, 2009, Pages 4156-4166

Rac1 signaling modulates BCL-6-mediated repression of gene transcription

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; HERMES ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; P21 ACTIVATED KINASE 1; PROTEIN BCL 6; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE;

EID: 67651204601     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01813-08     Document Type: Article
Times cited : (23)

References (73)
  • 2
    • 0031684844 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-κB p50
    • Baer, M., A. Dillner, R. C. Schwartz, C. Sedon, S. Nedospasov, and P. F. Johnson. 1998. Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-κB p50. Mol. Cell. Biol. 18:5678-5689.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 5678-5689
    • Baer, M.1    Dillner, A.2    Schwartz, R.C.3    Sedon, C.4    Nedospasov, S.5    Johnson, P.F.6
  • 3
    • 9944251987 scopus 로고    scopus 로고
    • Rho GTPases in human cancer: An unresolved link to upstream and downstream transcriptional regulation
    • Benitah, S. A., P. F. Valeron, L. van Aelst, C. J. Marshall, and J. C. Lacal. 2004. Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochim. Biophys. Acta 1705:121-132.
    • (2004) Biochim. Biophys. Acta , vol.1705 , pp. 121-132
    • Benitah, S.A.1    Valeron, P.F.2    van Aelst, L.3    Marshall, C.J.4    Lacal, J.C.5
  • 4
    • 0036898253 scopus 로고    scopus 로고
    • Acetylation inactivates the transcriptional repressor BCL6
    • Bereshchenko, O. R., W. Gu, and R. Dalla-Favera. 2002. Acetylation inactivates the transcriptional repressor BCL6. Nat. Genet. 32:606-613.
    • (2002) Nat. Genet , vol.32 , pp. 606-613
    • Bereshchenko, O.R.1    Gu, W.2    Dalla-Favera, R.3
  • 5
    • 0033053617 scopus 로고    scopus 로고
    • Reactive oxygen intermediate-dependent NF-κB activation by interleukin-1β requires 5-lipoxygenase or NADPH oxidase activity
    • Bonizzi, G., J. Piette, S. Schoonbroodt, R. Greimers, L. Havard, M. P. Merville, and V. Bours. 1999. Reactive oxygen intermediate-dependent NF-κB activation by interleukin-1β requires 5-lipoxygenase or NADPH oxidase activity. Mol. Cell. Biol. 19:1950-1960.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 1950-1960
    • Bonizzi, G.1    Piette, J.2    Schoonbroodt, S.3    Greimers, R.4    Havard, L.5    Merville, M.P.6    Bours, V.7
  • 6
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: Critical elements in the control of small G proteins
    • Bos, J. L., H. Rehmann, and A. Wittinghofer. 2007. GEFs and GAPs: critical elements in the control of small G proteins. Cell 129:865-877.
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 7
    • 33845868501 scopus 로고    scopus 로고
    • Evolution of the Rho family of ras-like GTPases in eukaryotes
    • Boureux, A., E. Vignal, S. Faure, and P. Fort. 2007. Evolution of the Rho family of ras-like GTPases in eukaryotes. Mol. Biol. Evol. 24:203-216.
    • (2007) Mol. Biol. Evol , vol.24 , pp. 203-216
    • Boureux, A.1    Vignal, E.2    Faure, S.3    Fort, P.4
  • 10
    • 0029902260 scopus 로고    scopus 로고
    • BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor
    • Chang, C. C., B. H. Ye, R. S. Chaganti, and R. Dalla-Favera. 1996. BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor. Proc. Natl. Acad. Sci. USA 93:6947-6952.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6947-6952
    • Chang, C.C.1    Ye, B.H.2    Chaganti, R.S.3    Dalla-Favera, R.4
  • 11
    • 0027195210 scopus 로고    scopus 로고
    • Cogswell, P. C., R. I. Scheinman, and A. S. Baldwin, Jr. 1993. Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL. J. Immunol. 150:2794-2804.
    • Cogswell, P. C., R. I. Scheinman, and A. S. Baldwin, Jr. 1993. Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL. J. Immunol. 150:2794-2804.
  • 13
  • 14
    • 21744432683 scopus 로고    scopus 로고
    • GDIs: Central regulatory molecules in Rho GTPase activation
    • DerMardirossian, C., and G. M. Bokoch. 2005. GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol. 15:356-363.
    • (2005) Trends Cell Biol , vol.15 , pp. 356-363
    • DerMardirossian, C.1    Bokoch, G.M.2
  • 15
    • 0034649504 scopus 로고    scopus 로고
    • Dhordain, P., O. Albagli, N. Honore, F. Guidez, D. Lantoine, M. Schmid, H. D. The, A. Zelent, and M. H. Koken. 2000. Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF. Oncogene 19:6240-6250.
    • Dhordain, P., O. Albagli, N. Honore, F. Guidez, D. Lantoine, M. Schmid, H. D. The, A. Zelent, and M. H. Koken. 2000. Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF. Oncogene 19:6240-6250.
  • 16
    • 0029670083 scopus 로고    scopus 로고
    • Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation
    • DiDonato, J., F. Mercurio, C. Rosette, J. Wu-Li, H. Suyang, S. Ghosh, and M. Karin. 1996. Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1295-1304.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 1295-1304
    • DiDonato, J.1    Mercurio, F.2    Rosette, C.3    Wu-Li, J.4    Suyang, H.5    Ghosh, S.6    Karin, M.7
  • 17
    • 0347949510 scopus 로고    scopus 로고
    • Molecular mechanisms of interleukin-10-mediated inhibition of NFkappaB activity: A role for p50
    • Driessler, F., K. Venstrom, R. Sabat, K. Asadullah, and A. J. Schottelius. 2004. Molecular mechanisms of interleukin-10-mediated inhibition of NFkappaB activity: a role for p50. Clin. Exp. Immunol. 135:64-73.
    • (2004) Clin. Exp. Immunol , vol.135 , pp. 64-73
    • Driessler, F.1    Venstrom, K.2    Sabat, R.3    Asadullah, K.4    Schottelius, A.J.5
  • 18
    • 8844264528 scopus 로고    scopus 로고
    • Cross-talk between Rac1 and dysregulated Wnt signaling pathway leads to cellular redistribution of β-catenin and TCF/LEF-mediated transcriptional activation
    • Esufali, S., and B. Bapat. 2004. Cross-talk between Rac1 and dysregulated Wnt signaling pathway leads to cellular redistribution of β-catenin and TCF/LEF-mediated transcriptional activation. Oncogene 23:8260-8271.
    • (2004) Oncogene , vol.23 , pp. 8260-8271
    • Esufali, S.1    Bapat, B.2
  • 19
    • 34047269793 scopus 로고    scopus 로고
    • Activation of tumor-specific splice variant Rac1b by Dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells
    • Esufali, S., G. S. Charames, V. V. Pethe, P. Buongiorno, and B. Bapat. 2007. Activation of tumor-specific splice variant Rac1b by Dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. Cancer Res. 67:2469-2479.
    • (2007) Cancer Res , vol.67 , pp. 2469-2479
    • Esufali, S.1    Charames, G.S.2    Pethe, V.V.3    Buongiorno, P.4    Bapat, B.5
  • 20
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S., and A. Hall. 2002. Rho GTPases in cell biology. Nature 420:629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 22
    • 0027184023 scopus 로고
    • The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers
    • Fujita, T., G. P. Nolan, H. C. Liou, M. L. Scott, and D. Baltimore. 1993. The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers. Genes Dev. 7:1354-1363.
    • (1993) Genes Dev , vol.7 , pp. 1354-1363
    • Fujita, T.1    Nolan, G.P.2    Liou, H.C.3    Scott, M.L.4    Baltimore, D.5
  • 23
    • 0035651254 scopus 로고    scopus 로고
    • Rho-family GTPases in cadherin-mediated cell-cell adhesion
    • Fukata, M., and K. Kaibuchi. 2001. Rho-family GTPases in cadherin-mediated cell-cell adhesion. Nat. Rev. Mol. Cell Biol. 2:887-897.
    • (2001) Nat. Rev. Mol. Cell Biol , vol.2 , pp. 887-897
    • Fukata, M.1    Kaibuchi, K.2
  • 24
    • 2442664118 scopus 로고    scopus 로고
    • Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
    • Gao, Y., J. B. Dickerson, F. Guo, J. Zheng, and Y. Zheng. 2004. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc. Natl. Acad. Sci. USA 101:7618-7623.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7618-7623
    • Gao, Y.1    Dickerson, J.B.2    Guo, F.3    Zheng, J.4    Zheng, Y.5
  • 25
    • 0030055727 scopus 로고    scopus 로고
    • Alternatively spliced variants of the cell adhesion molecule CD44 and tumour progression in colorectal cancer
    • Gotley, D. C., J. Fawcett, M. D. Walsh, J. A. Reeder, D. L. Simmons, and T. M. Antalis. 1996. Alternatively spliced variants of the cell adhesion molecule CD44 and tumour progression in colorectal cancer. Br. J. Cancer 74:342-351.
    • (1996) Br. J. Cancer , vol.74 , pp. 342-351
    • Gotley, D.C.1    Fawcett, J.2    Walsh, M.D.3    Reeder, J.A.4    Simmons, D.L.5    Antalis, T.M.6
  • 26
    • 15444363021 scopus 로고    scopus 로고
    • DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit
    • Guan, H., S. Hou, and R. P. Ricciardi. 2005. DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit. J. Biol. Chem. 280:9957-9962.
    • (2005) J. Biol. Chem , vol.280 , pp. 9957-9962
    • Guan, H.1    Hou, S.2    Ricciardi, R.P.3
  • 27
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. 1998. Rho GTPases and the actin cytoskeleton. Science 279:509-513.
    • (1998) Science , vol.279 , pp. 509-513
    • Hall, A.1
  • 28
    • 27844604200 scopus 로고    scopus 로고
    • Rho GTPases and the control of cell behaviour
    • Hall, A. 2005. Rho GTPases and the control of cell behaviour. Biochem. Soc. Trans. 33:891-895.
    • (2005) Biochem. Soc. Trans , vol.33 , pp. 891-895
    • Hall, A.1
  • 30
    • 34547699507 scopus 로고    scopus 로고
    • Expression of STAT3 and Bcl-6 oncoprotein in sodium arsenite-treated SV-40 immortalized human uroepithelial cells
    • Huang, Y. C., W. C. Hung, W. Y. Kang, W. T. Chen, and C. Y. Chai. 2007. Expression of STAT3 and Bcl-6 oncoprotein in sodium arsenite-treated SV-40 immortalized human uroepithelial cells. Toxicol. Lett. 173:57-65.
    • (2007) Toxicol. Lett , vol.173 , pp. 57-65
    • Huang, Y.C.1    Hung, W.C.2    Kang, W.Y.3    Chen, W.T.4    Chai, C.Y.5
  • 31
    • 0032511890 scopus 로고    scopus 로고
    • The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT
    • Huynh, K. D., and V. J. Bardwell. 1998. The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT. Oncogene 17:2473-2484.
    • (1998) Oncogene , vol.17 , pp. 2473-2484
    • Huynh, K.D.1    Bardwell, V.J.2
  • 32
    • 0034661112 scopus 로고    scopus 로고
    • BCoR, a novel corepressor involved in BCL-6 repression
    • Huynh, K. D., W. Fischle, E. Verdin, and V. J. Bardwell. 2000. BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev. 14:1810-1823.
    • (2000) Genes Dev , vol.14 , pp. 1810-1823
    • Huynh, K.D.1    Fischle, W.2    Verdin, E.3    Bardwell, V.J.4
  • 33
    • 0033581944 scopus 로고    scopus 로고
    • Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
    • Jordan, P., R. Brazão, M. G. Boavida, C. Gespach, and E. Chastre. 1999. Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors. Oncogene 18:6835-6839.
    • (1999) Oncogene , vol.18 , pp. 6835-6839
    • Jordan, P.1    Brazão, R.2    Boavida, M.G.3    Gespach, C.4    Chastre, E.5
  • 34
    • 0030801729 scopus 로고    scopus 로고
    • Expression of bcl-6 protein in normal skin and epidermal neoplasms
    • Kanazawa, N., M. Moriyama, T. Onizuka, K. Sugawara, and S. Mori. 1997. Expression of bcl-6 protein in normal skin and epidermal neoplasms. Pathol. Int. 47:600-607.
    • (1997) Pathol. Int , vol.47 , pp. 600-607
    • Kanazawa, N.1    Moriyama, M.2    Onizuka, T.3    Sugawara, K.4    Mori, S.5
  • 35
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: From innocent bystander to major culprit
    • Karin, M., Y. Cao, F. R. Greten, and Z. W. Li. 2002. NF-κB in cancer: from innocent bystander to major culprit. Nat. Rev. Cancer 2:301-310.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 37
    • 0033529715 scopus 로고    scopus 로고
    • Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A
    • Kazansky, A. V., E. B. Kabotyanski, S. L. Wyszomierski, M. A. Mancini, and J. M. Rosen. 1999. Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A. J. Biol. Chem. 274:22484-22492.
    • (1999) J. Biol. Chem , vol.274 , pp. 22484-22492
    • Kazansky, A.V.1    Kabotyanski, E.B.2    Wyszomierski, S.L.3    Mancini, M.A.4    Rosen, J.M.5
  • 39
    • 0027521432 scopus 로고
    • Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation
    • Lernbecher, T., U. Müller, and T. Wirth. 1993. Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature 365:767-770.
    • (1993) Nature , vol.365 , pp. 767-770
    • Lernbecher, T.1    Müller, U.2    Wirth, T.3
  • 41
    • 0141457523 scopus 로고    scopus 로고
    • The expression of bcl-2 and bcl-6 protein in normal and malignant transitional epithelium
    • Lin, Z., H. Kim, H. Park, Y. Kim, J. Cheon, and I. Kim. 2003. The expression of bcl-2 and bcl-6 protein in normal and malignant transitional epithelium. Urol. Res. 31:272-275.
    • (2003) Urol. Res , vol.31 , pp. 272-275
    • Lin, Z.1    Kim, H.2    Park, H.3    Kim, Y.4    Cheon, J.5    Kim, I.6
  • 43
    • 0347379871 scopus 로고    scopus 로고
    • Tumour-related alternativespliced Rac1b is not regulated by Rho-GDI and exhibits selective downstream signalling
    • Matos, P., J. Collard, and P. Jordan. 2003. Tumour-related alternativespliced Rac1b is not regulated by Rho-GDI and exhibits selective downstream signalling. J. Biol. Chem. 278:50442-50448.
    • (2003) J. Biol. Chem , vol.278 , pp. 50442-50448
    • Matos, P.1    Collard, J.2    Jordan, P.3
  • 44
    • 33744965194 scopus 로고    scopus 로고
    • RAC1, but not RAC1B, stimulates RELB-mediated gene transcription in colorectal cancer cells
    • Matos, P., and P. Jordan. 2006. RAC1, but not RAC1B, stimulates RELB-mediated gene transcription in colorectal cancer cells. J. Biol. Chem. 281: 13724-13732.
    • (2006) J. Biol. Chem , vol.281 , pp. 13724-13732
    • Matos, P.1    Jordan, P.2
  • 45
    • 33646548968 scopus 로고    scopus 로고
    • The 20S proteasome processes NFkappaB1 p105 into p50 in a translation-independent manner
    • Moorthy, A. K., O. V. Savinova, J. Q. Ho, V. Y. Wang, D. Vu, and G. Ghosh. 2006. The 20S proteasome processes NFkappaB1 p105 into p50 in a translation-independent manner. EMBO J. 25:1945-1956.
    • (2006) EMBO J , vol.25 , pp. 1945-1956
    • Moorthy, A.K.1    Savinova, O.V.2    Ho, J.Q.3    Wang, V.Y.4    Vu, D.5    Ghosh, G.6
  • 46
    • 0032128002 scopus 로고    scopus 로고
    • Antigen receptor signaling induces MAP kinase mediated phosphorylation and degradation of the BCL-6 transcription factor
    • Niu, H., B. H. Ye, and R. Dalla-Favera. 1998. Antigen receptor signaling induces MAP kinase mediated phosphorylation and degradation of the BCL-6 transcription factor. Genes Dev. 12:1953-1961.
    • (1998) Genes Dev , vol.12 , pp. 1953-1961
    • Niu, H.1    Ye, B.H.2    Dalla-Favera, R.3
  • 47
    • 0036937410 scopus 로고    scopus 로고
    • The proto-oncogene BCL-6 in normal and malignant B cell development
    • Niu, H. 2002. The proto-oncogene BCL-6 in normal and malignant B cell development. Hematol. Oncol. 20:155-166.
    • (2002) Hematol. Oncol , vol.20 , pp. 155-166
    • Niu, H.1
  • 48
    • 24044453683 scopus 로고    scopus 로고
    • The proto-oncogene BCL-6 is expressed in olfactory sensory neurons
    • Otaki, J. M., D. T. Fearon, and H. Yamamoto. 2005. The proto-oncogene BCL-6 is expressed in olfactory sensory neurons. Neurosci. Res. 53:189-200.
    • (2005) Neurosci. Res , vol.53 , pp. 189-200
    • Otaki, J.M.1    Fearon, D.T.2    Yamamoto, H.3
  • 49
    • 6344272990 scopus 로고    scopus 로고
    • Rac1 contributes to maximal activation of STAT1 and STAT3 in IFN-gamma-stimulated rat astrocytes
    • Park, E. J., K. A. Ji, S. B. Jeon, W. H. Choi, I. O. Han, H. J. You, J. H. Kim, I. Jou, and E. H. Joe. 2004. Rac1 contributes to maximal activation of STAT1 and STAT3 in IFN-gamma-stimulated rat astrocytes. J. Immunol. 173:5697-5703.
    • (2004) J. Immunol , vol.173 , pp. 5697-5703
    • Park, E.J.1    Ji, K.A.2    Jeon, S.B.3    Choi, W.H.4    Han, I.O.5    You, H.J.6    Kim, J.H.7    Jou, I.8    Joe, E.H.9
  • 50
    • 34548706562 scopus 로고    scopus 로고
    • Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells
    • Phan, R. T., M. Saito, Y. Kitagawa, A. R. Means, and R. Dalla-Favera. 2007. Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. Nat. Immunol. 8:1132-1139.
    • (2007) Nat. Immunol , vol.8 , pp. 1132-1139
    • Phan, R.T.1    Saito, M.2    Kitagawa, Y.3    Means, A.R.4    Dalla-Favera, R.5
  • 51
    • 0037227965 scopus 로고    scopus 로고
    • CD44: From adhesion molecules to signalling regulators
    • Ponta, H., L. Sherman, and P. A. Herrlich. 2003. CD44: from adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell Biol. 4:33-45.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 52
    • 0037119423 scopus 로고    scopus 로고
    • Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype
    • Rennefahrt, U. E., B. Illert, E. Kerkhoff, J. Troppmair, and U. R. Rapp. 2002. Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype. J. Biol. Chem. 277:29510-29518.
    • (2002) J. Biol. Chem , vol.277 , pp. 29510-29518
    • Rennefahrt, U.E.1    Illert, B.2    Kerkhoff, E.3    Troppmair, J.4    Rapp, U.R.5
  • 53
    • 0035575585 scopus 로고    scopus 로고
    • Rho family proteins: Coordinating cell responses
    • Ridley, A. J. 2001. Rho family proteins: coordinating cell responses. Trends Cell Biol. 11:471-477.
    • (2001) Trends Cell Biol , vol.11 , pp. 471-477
    • Ridley, A.J.1
  • 54
    • 0031972103 scopus 로고    scopus 로고
    • Expression of CD44 and variant proteins in human colorectal cancer and its relevance for prognosis
    • Ropponen, K. M., M. J. Eskelinen, P. K. Lipponen, E. Alhava, and V. M. Kosma. 1998. Expression of CD44 and variant proteins in human colorectal cancer and its relevance for prognosis. Scand. J. Gastroenterol. 33:301-309.
    • (1998) Scand. J. Gastroenterol , vol.33 , pp. 301-309
    • Ropponen, K.M.1    Eskelinen, M.J.2    Lipponen, P.K.3    Alhava, E.4    Kosma, V.M.5
  • 55
    • 67651213890 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted.
  • 57
    • 0035920174 scopus 로고    scopus 로고
    • Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase C delta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation
    • Schuringa, J. J., L. V. Dekker, E. Vellenga, and W. Kruijer. 2001. Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase C delta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation. J. Biol. Chem. 276:27709-27715.
    • (2001) J. Biol. Chem , vol.276 , pp. 27709-27715
    • Schuringa, J.J.1    Dekker, L.V.2    Vellenga, E.3    Kruijer, W.4
  • 58
    • 0031105660 scopus 로고    scopus 로고
    • Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
    • Sells, M. A., U. G. Knaus, S. Bagrodia, D. M. Ambrose, G. M. Bokoch, and J. Chernoff. 1997. Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr. Biol. 7:202-210.
    • (1997) Curr. Biol , vol.7 , pp. 202-210
    • Sells, M.A.1    Knaus, U.G.2    Bagrodia, S.3    Ambrose, D.M.4    Bokoch, G.M.5    Chernoff, J.6
  • 59
    • 0029899571 scopus 로고    scopus 로고
    • Transcriptional repression by the proto-oncogene BCL-6
    • Seyfert, V. L., D. Allman, Y. He, and L. M. Staudt. 1996. Transcriptional repression by the proto-oncogene BCL-6. Oncogene 12:2331-2342.
    • (1996) Oncogene , vol.12 , pp. 2331-2342
    • Seyfert, V.L.1    Allman, D.2    He, Y.3    Staudt, L.M.4
  • 60
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • Shaffer, A. L., X. Yu, Y. He, J. Boldrick, E. P. Chan, and L. M. Staudt. 2000. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 13:199-212.
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1    Yu, X.2    He, Y.3    Boldrick, J.4    Chan, E.P.5    Staudt, L.M.6
  • 62
    • 11244313840 scopus 로고    scopus 로고
    • Singh, A., A. E. Karnoub, T. R. Palmby, E. Lengyel, J. Sondek, and J. C. Der. 2004. Rac1b, a tumour associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene 23:9369-9380.
    • Singh, A., A. E. Karnoub, T. R. Palmby, E. Lengyel, J. Sondek, and J. C. Der. 2004. Rac1b, a tumour associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene 23:9369-9380.
  • 63
    • 0037059745 scopus 로고    scopus 로고
    • RelB cellular regulation and transcriptional activity are regulated by p100
    • Solan, N. J., H. Miyoshi, E. M. Carmona, G. D. Bren, and C. V. Paya. 2002. RelB cellular regulation and transcriptional activity are regulated by p100. J. Biol. Chem. 277:1405-1418.
    • (2002) J. Biol. Chem , vol.277 , pp. 1405-1418
    • Solan, N.J.1    Miyoshi, H.2    Carmona, E.M.3    Bren, G.D.4    Paya, C.V.5
  • 64
    • 0032773607 scopus 로고    scopus 로고
    • Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6
    • Staudt, L. M., A. L. Dent, A. L. Shaffer, and X. Yu. 1999. Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6. Int. Rev. Immunol. 18:381-403.
    • (1999) Int. Rev. Immunol , vol.18 , pp. 381-403
    • Staudt, L.M.1    Dent, A.L.2    Shaffer, A.L.3    Yu, X.4
  • 67
    • 9444254649 scopus 로고    scopus 로고
    • GTPaseactivating protein binds STAT3 and is required for IL-6-induced STAT3 activation and for differentiation of a leukemic cell line
    • Tonozuka, Y., Y. Minoshima, Y. C. Bao, Y. Moon, Y. Tsubono, T. Hatori, H. Nakajima, T. Nosaka, T. Kawashima, and T. A. Kitamura. 2004. GTPaseactivating protein binds STAT3 and is required for IL-6-induced STAT3 activation and for differentiation of a leukemic cell line. Blood 104:3550-3557.
    • (2004) Blood , vol.104 , pp. 3550-3557
    • Tonozuka, Y.1    Minoshima, Y.2    Bao, Y.C.3    Moon, Y.4    Tsubono, Y.5    Hatori, T.6    Nakajima, H.7    Nosaka, T.8    Kawashima, T.9    Kitamura, T.A.10
  • 68
    • 9644268197 scopus 로고    scopus 로고
    • BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages
    • Wessells, J., M. Baer, H. A. Young, E. Claudio, K. Brown, U. Siebenlist, and P. F. Johnson. 2004. BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages. J. Biol. Chem. 279: 49995-50003.
    • (2004) J. Biol. Chem , vol.279 , pp. 49995-50003
    • Wessells, J.1    Baer, M.2    Young, H.A.3    Claudio, E.4    Brown, K.5    Siebenlist, U.6    Johnson, P.F.7
  • 69
    • 0037081677 scopus 로고    scopus 로고
    • The Rho GTPase family: A Racs to Wrchs story
    • Wherlock, M., and M. Mellor. 2002. The Rho GTPase family: a Racs to Wrchs story. J. Cell Sci. 115:239-240.
    • (2002) J. Cell Sci , vol.115 , pp. 239-240
    • Wherlock, M.1    Mellor, M.2
  • 72
    • 33846117134 scopus 로고    scopus 로고
    • The signaling mechanism of ROS in tumor progression
    • Wu, W. S. 2006. The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev. 25:695-705.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 695-705
    • Wu, W.S.1
  • 73
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
    • Zhong, H., M. J. May, E. Jimi, and S. Ghosh. 2002. The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 9:625-636.
    • (2002) Mol. Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.