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Volumn 173, Issue 9, 2004, Pages 5697-5703

Rac1 contributes to maximal activation of STAT1 and STAT3 in IFN-γ-stimulated rat astrocytes

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; GAMMA INTERFERON RECEPTOR ALPHA; GLUTATHIONE TRANSFERASE; GUANOSINE TRIPHOSPHATASE; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; P21 ACTIVATED KINASE; PHOSPHOTRANSFERASE; RAC1 PROTEIN; RACN17 PROTEIN; RECEPTOR SUBUNIT; STAT1 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 6344272990     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.9.5697     Document Type: Article
Times cited : (47)

References (37)
  • 1
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: Cellular and molecular cues to biological function
    • Ridet, I. L., S. K. Malhotra, A. Privat, and F. H. Gage. 1997. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci. 20:570.
    • (1997) Trends Neurosci. , vol.20 , pp. 570
    • Ridet, I.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 2
    • 0031874792 scopus 로고    scopus 로고
    • Inflammation in the CNS: Balance between immunological privilege and immune responses
    • Matyszak, M. K. 1998. Inflammation in the CNS: balance between immunological privilege and immune responses. Prog. Neurobiol. 56:19.
    • (1998) Prog. Neurobiol. , vol.56 , pp. 19
    • Matyszak, M.K.1
  • 5
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J. E., Jr., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415.
    • (1994) Science , vol.264 , pp. 1415
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 7
    • 0025734387 scopus 로고
    • γ-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo
    • Yong, V. W., R. Moumdjian, F. P. Yong, T. C. Ruijs, M. S. Freedman, N. Cashman, and J. P. Antel. 1991. γ-Interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo. Proc. Natl. Acad. Sci. USA 88:7016.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7016
    • Yong, V.W.1    Moumdjian, R.2    Yong, F.P.3    Ruijs, T.C.4    Freedman, M.S.5    Cashman, N.6    Antel, J.P.7
  • 8
    • 0025304816 scopus 로고
    • Tumor necrosis factor-α production by astrocytes: Induction by lipopolysaccharide, IFN-γ, and IL-1β
    • Chung, I. Y., and E. N. Benveniste. 1990. Tumor necrosis factor-α production by astrocytes: induction by lipopolysaccharide, IFN-γ, and IL-1β. J. Immunol. 144:2999.
    • (1990) J. Immunol. , vol.144 , pp. 2999
    • Chung, I.Y.1    Benveniste, E.N.2
  • 12
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong, Z., Z. Wen, and J. E. Darnell, Jr. 1994. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264:95.
    • (1994) Science , vol.264 , pp. 95
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 13
    • 0038496288 scopus 로고    scopus 로고
    • Involvement of JAK/STAT (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway
    • Park, E. S., H. Kim, J. M. Sub, S. I. Park, S. H. You, H. K. Chung, K. W. Lee, O. Y. Kwon, B. Y. Cho, Y. K. Kim, et al. 2000. Involvement of JAK/STAT (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway. Mol. Endocrinol. 14:662.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 662
    • Park, E.S.1    Kim, H.2    Sub, J.M.3    Park, S.I.4    You, S.H.5    Chung, H.K.6    Lee, K.W.7    Kwon, O.Y.8    Cho, B.Y.9    Kim, Y.K.10
  • 14
    • 0037313015 scopus 로고    scopus 로고
    • Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors
    • Pelletier, S., F. Duhamel, P. Coulombe, M. R. Popoff, and S. Meloche. 2003. Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. Mol. Cell. Biol. 23:1316.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1316
    • Pelletier, S.1    Duhamel, F.2    Coulombe, P.3    Popoff, M.R.4    Meloche, S.5
  • 16
    • 0037422525 scopus 로고    scopus 로고
    • Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation
    • Horiuchi, M., T. X. Cui, Z. Li, J. M. Li, H. Nakagami, and M. Iwai. 2003. Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation. Circulation 107:106.
    • (2003) Circulation , vol.107 , pp. 106
    • Horiuchi, M.1    Cui, T.X.2    Li, Z.3    Li, J.M.4    Nakagami, H.5    Iwai, M.6
  • 21
    • 0033082165 scopus 로고    scopus 로고
    • Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense
    • Roberts, A. W., C. Kim, L. Zhen, J. B. Lowe, R. Kapur, B. Petryniak, A. Spaetti, J. D. Pollock, J. B. Borneo, G. B. Bradford, et al. 1999. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity 10:183.
    • (1999) Immunity , vol.10 , pp. 183
    • Roberts, A.W.1    Kim, C.2    Zhen, L.3    Lowe, J.B.4    Kapur, R.5    Petryniak, B.6    Spaetti, A.7    Pollock, J.D.8    Borneo, J.B.9    Bradford, G.B.10
  • 22
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Giulian, D., and T. J. Baker. 1986. Characterization of ameboid microglia isolated from developing mammalian brain. J. Neurosci. 6:2163.
    • (1986) J. Neurosci. , vol.6 , pp. 2163
    • Giulian, D.1    Baker, T.J.2
  • 24
    • 0037106353 scopus 로고    scopus 로고
    • Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to β-amyloid in C6 astroglioma cells
    • Lee, M., H. I. You, S. H. Cho, C. H. Woo, M. H. Yoo, E. H. Joe, and J. H. Kim. 2002. Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to β-amyloid in C6 astroglioma cells. Biochem. J. 366:937.
    • (2002) Biochem. J. , vol.366 , pp. 937
    • Lee, M.1    You, H.I.2    Cho, S.H.3    Woo, C.H.4    Yoo, M.H.5    Joe, E.H.6    Kim, J.H.7
  • 25
    • 0032535352 scopus 로고    scopus 로고
    • Two γ-interferon-activation sites (GAS) on the promoter of the human intercellular adhesion molecule (ICAM-1) gene are required for induction of transcription by IFN-γ
    • Tessitore, A., L. Pastore, A. Rispoli, L. Cilenti, E. Toniato, V. Flati, A. R. Farina, L. Frati, A. Gulino, and S. Martinotti. 1998. Two γ-interferon-activation sites (GAS) on the promoter of the human intercellular adhesion molecule (ICAM-1) gene are required for induction of transcription by IFN-γ. Eur. J. Biochem. 258:968.
    • (1998) Eur. J. Biochem. , vol.258 , pp. 968
    • Tessitore, A.1    Pastore, L.2    Rispoli, A.3    Cilenti, L.4    Toniato, E.5    Flati, V.6    Farina, A.R.7    Frati, L.8    Gulino, A.9    Martinotti, S.10
  • 26
    • 2642617812 scopus 로고    scopus 로고
    • IFN-γ induction of the human monocyte chemoattractant protein (hMCP)-1 gene in astrocytoma cells: Functional interaction between an IFN-γ-activated site and a GC-rich element
    • Zhou, Z. H., P. Chaturvedi, Y. L. Han, S. Aras, Y. S. Li, P. E. Kolattukudy, D. Ping, J. M. Boss, and R. M. Ransohoff. 1998. IFN-γ induction of the human monocyte chemoattractant protein (hMCP)-1 gene in astrocytoma cells: functional interaction between an IFN-γ-activated site and a GC-rich element. J. Immunol. 160:3908.
    • (1998) J. Immunol. , vol.160 , pp. 3908
    • Zhou, Z.H.1    Chaturvedi, P.2    Han, Y.L.3    Aras, S.4    Li, Y.S.5    Kolattukudy, P.E.6    Ping, D.7    Boss, J.M.8    Ransohoff, R.M.9
  • 27
    • 0037679015 scopus 로고    scopus 로고
    • Rac proteins and the control of axon development
    • Lundquist, E. A. 2003. Rac proteins and the control of axon development. Curr. Opin. Neurobiol. 13:384.
    • (2003) Curr. Opin. Neurobiol. , vol.13 , pp. 384
    • Lundquist, E.A.1
  • 28
    • 0037215397 scopus 로고    scopus 로고
    • Regulation of neutrophil function by Rac GTPases
    • Dinauer, M. C. 2003. Regulation of neutrophil function by Rac GTPases. Curr. Opin. Hematol. 10:8.
    • (2003) Curr. Opin. Hematol. , vol.10 , pp. 8
    • Dinauer, M.C.1
  • 29
    • 0035575585 scopus 로고    scopus 로고
    • Rho family proteins: Coordinating cell responses
    • Ridley, A. J. 2001. Rho family proteins: coordinating cell responses. Trends Cell Biol. 11:471.
    • (2001) Trends Cell Biol. , vol.11 , pp. 471
    • Ridley, A.J.1
  • 31
    • 0030888167 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the vav proto-oncogene product links FcεRI to the Rac1-JNK pathway
    • Teramoto, H., P. Salem, K. C. Robbins, X. R. Bustelo, and I. S. Gutkind. 1997. Tyrosine phosphorylation of the vav proto-oncogene product links FcεRI to the Rac1-JNK pathway. J. Biol. Chem. 272:10751.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10751
    • Teramoto, H.1    Salem, P.2    Robbins, K.C.3    Bustelo, X.R.4    Gutkind, I.S.5
  • 32
    • 0031456722 scopus 로고    scopus 로고
    • Bacterial LPS and IFN-γ trigger the tyrosine phosphorylation of vav in macrophages: Evidence for involvement of the hck tyrosine kinase
    • English, B. K., S. L. Orlicek, Z. Mei, and E. A. Meals. 1997. Bacterial LPS and IFN-γ trigger the tyrosine phosphorylation of vav in macrophages: evidence for involvement of the hck tyrosine kinase. J. Leukocyte Biol. 62:859.
    • (1997) J. Leukocyte Biol. , vol.62 , pp. 859
    • English, B.K.1    Orlicek, S.L.2    Mei, Z.3    Meals, E.A.4
  • 33
    • 0034688314 scopus 로고    scopus 로고
    • vav associates with the type I interferon (IFN) receptor and contributes to the antiproliferative effect of IFN-γ in megakaryocytic cell lines
    • vav associates with the type I interferon (IFN) receptor and contributes to the antiproliferative effect of IFN-γ in megakaryocytic cell lines. Oncogene 19:387.
    • (2000) Oncogene , vol.19 , pp. 387
    • Micouin, A.1    Wietzerbin, J.2    Steunou, V.3    Martyre, M.C.4
  • 34
    • 0027910431 scopus 로고
    • Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
    • Egan, S. E., B. W. Giddings, M. W. Brooks, L. Buday, A. M. Sizeland, and R. A. Weinberg. 1993. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363:45.
    • (1993) Nature , vol.363 , pp. 45
    • Egan, S.E.1    Giddings, B.W.2    Brooks, M.W.3    Buday, L.4    Sizeland, A.M.5    Weinberg, R.A.6
  • 35
    • 0033828672 scopus 로고    scopus 로고
    • SOCS: Physiological suppressors of cytokine signaling
    • Krebs, D. L., and D. J. Hilton. 2000. SOCS: physiological suppressors of cytokine signaling. J. Cell Sci. 113:2813.
    • (2000) J. Cell Sci. , vol.113 , pp. 2813
    • Krebs, D.L.1    Hilton, D.J.2
  • 36
    • 0038352039 scopus 로고    scopus 로고
    • 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia
    • Park, E. J., S. Y. Park, E. H. Joe, and I. Jou. 2003. 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. J. Biol. Chem. 278:14747.
    • (2003) J. Biol. Chem. , vol.278 , pp. 14747
    • Park, E.J.1    Park, S.Y.2    Joe, E.H.3    Jou, I.4


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