Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: Proliferative and inflammatory disorders and a possible role of androgens

Toxicology

Volumn 262, Issue 3, 2009, Pages 215-223

  Scarano, Wellerson Rodrigo ^a   Toledo, Fabíola Choqueta de ^b   Guerra, Marina Trevizan ^a   Campos, Silvana Gisele Pegorin de ^a   Júnior, Luís Antonio Justulin ^b   Felisbino, Sérgio Luis ^a   Anselmo Franci, Janete A ^c   Taboga, Sebastião Roberto ^a   Kempinas, Wilma De Grava ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

AR expression; DBP; Epithelial proliferation; Inflammation; Prostate

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; COLLAGEN FIBRIL; CORN OIL; GELATINASE A; GELATINASE B; KI 67 ANTIGEN; PHTHALIC ACID DIBUTYL ESTER; TESTOSTERONE;

ANIMAL EUTHANASIA; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FEMALE; FETUS DEVELOPMENT; GESTATION PERIOD; GONAD DEVELOPMENT; HISTOCHEMISTRY; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; LACTATION; MALE; NONHUMAN; ORGAN WEIGHT; PERINATAL PERIOD; PRIORITY JOURNAL; PROSTATE EPITHELIUM; PROSTATECTOMY; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN EXPRESSION; RAT; ZYMOGRAPHY;

ANIMALS; CELL PROLIFERATION; DIBUTYL PHTHALATE; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROSTATE; PROSTATIC INTRAEPITHELIAL NEOPLASIA; RATS; RATS, WISTAR; RECEPTORS, ANDROGEN; STROMAL CELLS; TESTIS; TESTOSTERONE; TIME FACTORS;

ANIMALIA; RATTUS; ZEA MAYS;

EID: 67651042490     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.06.011     Document Type: Article

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