Early-onset endocrine disruptor-induced prostatitis in the rat

Environmental Health Perspectives

Volumn 116, Issue 7, 2008, Pages 923-929

  Cowin, Prue A ^a   Foster, Paul ^b   Pedersen, John ^c   Hedwards, Shelley ^a   McPherson, Stephen J ^a   Risbridger, Gail P ^a  

^a MONASH UNIVERSITY   (Australia)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c Tissupath Pty Ltd   (Australia)

Author keywords

Antiandrogen; Endocrine disruptors; Inflammation; Prostate; Prostatitis; Vinclozolin

Indexed keywords

ANDROGEN RECEPTOR; ENDOCRINE DISRUPTOR; FIBROBLAST GROWTH FACTOR 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; TRANSFORMING GROWTH FACTOR BETA1; VINCLOZOLIN;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; BRANCHING MORPHOGENESIS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; FETUS; GONAD DEVELOPMENT; HISTOPATHOLOGY; MALE; NEWBORN PERIOD; NONHUMAN; PRECANCER; PRENATAL EXPOSURE; PREPUBERTY; PRIORITY JOURNAL; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATITIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ACTIVE TRANSPORT, CELL NUCLEUS; ANDROGEN ANTAGONISTS; ANIMALS; CELL NUCLEUS; EPITHELIUM; FEMALE; HUMANS; INTERLEUKIN-8; MALE; MATERNAL-FETAL EXCHANGE; MORPHOGENESIS; NF-KAPPA B; OXAZOLES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROSTATE; PROSTATITIS; RATS; RATS, SPRAGUE-DAWLEY; SEXUAL MATURATION; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA; RATTUS;

EID: 46749131542     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.11239     Document Type: Article

References (41)

1. Almahbobi G, Hall PF. 1993. Indirect immunofluorescence modified to display two antigens with one light filter. Histochem J 25(1):14-18.
2. Almahbobi G, Hedwards S, Fricout G, Jeulin D, Bertram JF, Risbridger GP. 2005. Computer-based detection of neonatal changes to branching morphogenesis reveals different mechanisms of and predicts prostate enlargement in mice haplo-insufficient for bone morphogenetic protein 4. J Pathol 206(1):52-61.
3. Anway MD, Cupp AS, Uzumcu M, Skinner MK. 2005. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308(5727):1466-1469.
4. Anway MD, Leathers C, Skinner MK. 2006. Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology 147(12):5515-5523.
5. Balanathan P, Ball EM, Wang H, Harris SE, Shelling AN, Risbridger GP. 2004. Epigenetic regulation of inhibin alpha-subunit gene in prostate cancer cell lines. J Mol Endocrinol 32(1):55-67.
6. Bertram JF. 1995. Analyzing renal glomeruli with the new stereology. Int Rev Cytol 161:111-172.
7. Bianco JJ, Handelsman DJ, Pedersen JS, Risbridger GP. 2002. Direct response of the murine prostate gland and seminal vesicles to estradiol. Endocrinology 143(12):4922-4933.
8. Calhoun EA, McNaughton Collins M, Pontari MA, O'Leary M, Leiby BE, Landis RJ, et al. 2004. The economic impact of chronic prostatitis. Arch Intern Med 164(11):1231-1236.
9. Coffey DS. 2001. Similarities of prostate and breast cancer: evolution, diet, and estrogens. Urology 57(4 suppl 1):31-38.
10. Cullen-McEwen LA, Fricout G, Harper IS, Jeulin D, Bertram JF. 2002. Quantitation of 3D ureteric branching morphogenesis in cultured embryonic mouse kidney. Int J Dev Biol 46(8):1049-1055.
11. Cunha G, Alarid E, Turner T, Donjacour A, Boutin E, Foster B. 1992. Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors. J Androl 13(6):465-475.
12. De Bosscher K, Vanden Berghe W, Haegeman G. 2006. Cross-talk between nuclear receptors and nuclear factor kappaB. Oncogene 25(51):6868-6886.
13. Foster PM. 2006. Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters. Int J Androl 29(1):140-147.
14. Foster PM, McIntyre BS. 2002. Endocrine active agents: implications of adverse and non-adverse changes. Toxicol Pathol 30(1):59-65.
15. Fricout G, Cullen-McEwen L, Harper IS, Jeulin D, Bertram JF. 2001. A quantitative method for analysing 3D branching in embryonic kidneys: development of a technique and preliminary data. Image Anal Stereol 20(suppl 1):36-41.
16. Gray LE Jr, Ostby JS, Kelce WR. 1994. Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat. Toxicol Appl Pharmacol 129(1):46-52.
17. Harkonen PL, Makela SI. 2004. Role of estrogens in development of prostate cancer. J Steroid Biochem Mol Biol 92(4):297-305.
18. Huang L, Pu Y, Alam S, Birch L, Prins GS. 2005. The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens. Dev Biol 278(2):396-414.
19. Keice WR, Monosson E, Gamcsik MP, Laws SC, Gray LE Jr. 1994. Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites. Toxicol Appl Pharmacol 126(2):276-285.
20. Kelce WR, Wilson EM. 1997. Environmental antiandrogens: developmental effects, molecular mechanisms, and clinical implications. J Mol Med 75(3):198-207.
21. Korenbrot CC, Huhtaniemi IT, Weiner RI. 1977. Preputial separation as an external sign of pubertal development in the male rat. Biol Reprod 17(2):298-303
22. Laczkó I, Hudson DL, Freeman A, Feneley MR, Masters JR. 2004. Comparison of the zones of the human prostate with the seminal vesicle: morphology, immunohistochemistry, and cell kinetics. Prostate 62:260-266.
23. Litwin M, Saigal C, eds. 2007. Urologic Diseases in America. Bethesda, MD:National Institutes of Health. Available: http://kidney.niddk.nih.gov/ statistics/uda/index.htm [accessed 4 June 2008].
24. Ly LP, Jimenez M, Zhuang TN, Celermajer DS, Conway AJ, Handelsman DJ. 2001. A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency. J Clin Endocrinol Metab 86(9):4078-4088.
25. McNaughton-Collins M, Joyce G, Wise M, Pontari M. 2007. Prostatitis. In: Urologic Diseases in America (Litwin M, Saigal C, eds). Bethesda, MD:National Institutes of Health, 11-41. Available: http://kidney.niddk.nih.gov/statistics/uda/Prostatitis-Chapter01.pdf [accessed 4 June 2008].
26. McNaughton Collins M, Pontari MA, O'Leary MP, Calhoun EA, Santanna J, Landis JR, et al, 2001. Quality of life is impaired in man with chronic prostatitis: the Chronic Prostatitis Collaborative Research Network. J Gen Intern Med 16(10):656-662.
27. McPherson S, Wang H, Jones M, Pederson J, Iismaa T, Wreford N, et al. 2001. Elevated androgens and prolactin in aromatase deficient (ArKO) mice cause enlargement but not malignancy of the prostate gland. Endocrinology 142(6):2458-2467.
28. Meachem SJ, McLachlan RI, de Kretser DM, Robertson DM, Wreford NG. 1996. Neonatal exposure of rats to recombinant follicle stimulating hormone increases adult Sertoli and spermatogenic cell numbers. Biol Reprod 54(1):36-44.
29. Naslund MJ, Strandberg JD, Coffey DS. 1988. The role of androgens and estrogens in the pathogenesis of experimental nonbacterial prostatitis. J Urol 140(5):1049-1053.
30. National Center for Biotechnology Information. 2008. Unigene. Available: http://www.ncbi.nlm.nih.gov/sites/entrez?db=unigene [accessed 3 June 2008].
31. Prins G. 1997. Developmental estrogenization of the prostate gland. In: Prostate: Basic and Clinical Aspects (Naz R, ed). New York: CRC Press, 245-263.
32. Prins G, Birch L. 1995. The developmental pattern at androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen. Endocrinology 136(3):1303-1314.
33. Risbridger GP, Wang H, Frydenberg M, Cunha G. 2001. The metaplastic effects of estrogen on mouse prostate epithelium: proliferation of cells with basal cell phenotype. Endocrinology 142(6):2443-2450.
34. Singh J, Zhu Q, Handelsman DJ. 1999. Stereological evaluation of mouse prostate development. J Androl 20(2):251-258.
35. Stoker TE, Laws SC, Guidici DL, Cooper RL. 2000. The effect of atrazine on puberty in male Wistar rats: an evaluation in the protocol for the assessmant of pubertal development and thyroid function. Toxicol Sci 58(1):50-59.
36. Stoker TE, Robinette CL, Cooper RL. 1999. Perinatal exposure to estrogenic compounds and the subsequent effects an the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes. Reprod Toxicol 13(6):463-472.
37. Szeto SY, Burlinson NE, Rahe JE, Oloffs PC. 1989. Kinetics of hydrolysis of the dicarboximide fungicide vinclozolin. J Agric Food Chem 37:525-529.
38. Turner JA, Ciol MA, Von Korff M, Berger R. 2005. Health concerns of patients with nonbacterial prostatitis/pelvic pain. Arch Intern Med 165(9):1054-1059.
39. Wang Y, Hayward S, Cao M, Thayer K, Cunha G. 2001. Cell differentiation lineage in the prostate. Differentiation 68(4-5):270-279.
40. Wolf CJ, LeBlanc GA, Ostby JS, Gray LE Jr. 2000. Characterization of the period of sensitivity of fetal male sexual development to vinclozolin. Toxicol Sci 55(1):152-161.
41. Wong C, Kelce WR, Sar M, Wilson EM. 1995. Androgen receptor antagonist versus aganist activities of the fungicide vinclozolin relative to hydroxyflutamide. J Biol Chem 270(34):19998-20003.